1. University of Heidelberg

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    1. Mentioned In 55 Articles

    2. Diagnostic Accuracy of 870-nm Spectral-Domain OCT with Enhanced Depth Imaging for the Detection of Caries beneath Ceramics

      Diagnostic Accuracy of 870-nm Spectral-Domain OCT with Enhanced Depth Imaging for the Detection of Caries beneath Ceramics
      Abstract Objectives To evaluate the diagnostic accuracy of optical coherence tomography (OCT) for the non-invasive detection of caries adjacent to ceramic materials. Methods Disks made from five ceramic materials (hybrid ceramic, feldspathic ceramic, zirconia-reinforced lithium silicate, lithium disilicate, and high-translucent zirconia) were ground to the recommended material thickness for single crown restorations and laminated with a 100m thick layer of one of three adhesive cements. The disks were fixed to ...
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    3. OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

      OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial
      Objectives The aim of this single-center randomized controlled trial (NCT03753256) was to assess orthodontic surface sealant layer thickness and integrity in vivo during a 12-month follow-up by optical coherence tomography (OCT). Materials and methods Using a split-mouth design, quadrants of 20 patients treated with fixed orthodontic appliances were included. Quadrants were randomly assigned to the sealants Pro Seal (PS) or Opal Seal (OS). OCT scans were performed immediately after the ...
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    4. Demineralization detection in orthodontics using an ophthalmic optical coherence tomography device equipped with a multicolor fluorescence module

      Demineralization detection in orthodontics using an ophthalmic optical coherence tomography device equipped with a multicolor fluorescence module
      Objectives Demineralizations such as white spot lesions are among the most prevalent side effects during orthodontic treatment. Fluorescence devices, including quantitative light-induced fluorescence (QLF), exploiting the intrinsic fluorescence of enamel and teeth and most recently optical coherence tomography (OCT) were introduced for early demineralization detection. In addition to near-infrared OCT scanning, multicolor modules allow for imaging with different laser wavelengths and the detection of reflective- and fluorescent light. The aim ...
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    5. Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction

      Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction
      Multimodal imaging techniques were performed in a patient with a newly emerged visual field defect; a missing retinal lesion on fundus examination made the diagnosis challenging but infrared imaging showed a larger area of retinal abnormality temporal to the fovea. Indocyanine green angiography (IA) showed late hypofluorescence and there was mild hyperautofluorescence which is known from acute zonal occult outer retinopathy (AZOOR). Despite normal fluorescein angiography (FA) results, a perfusion ...
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    6. Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis

      Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis
      Background The broad spectrum of uveitis disorders requires a multimodal imaging approach in the daily practice of an ophthalmologist. As inflammatory conditions, they have in common an alteration in leukocyte migration. In this context, optical coherence tomography angiography (OCTA) might be of great value for diagnosing or following up patients with these disorders. To date, OCTA has rather been used as an additional tool besides the well-established diagnostic imaging tools ...
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    7. OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes

      OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes
      Purpose To assess anterior scleral canal opening (ASCO) offset relative to Bruchs membrane opening (BMO) (ASCO/BMO offset) so as to determine neural canal direction, obliqueness, and minimum cross-sectional area (NCMCA) in 362 healthy eyes. Design Cross-sectional study Methods After OCT optic nerve head (ONH) and retinal nerve fiber layer thickness (RNFLT) imaging, BMO and ASCO were manually segmented and planes, centroids, size and shape were calculated. Neural canal direction ...
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    8. Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study

      Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study
      Purpose : To quantify peripapillary choroidal thickness (PCT) and the factors that influence it in healthy participants who represent the racial and ethnic composition of the U.S. population. Methods : A total of 362 healthy participants underwent optical coherence tomography (OCT) enhanced depth imaging of the optic nerve head with a 24 radial B-scan pattern aligned to the fovea to Bruch's membrane opening axis. Bruch's membrane, anterior scleral canal ...
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    9. Evaluation of Optical Coherence Tomography in Dentistry

      Evaluation of Optical Coherence Tomography in Dentistry
      Optical coherence tomography (OCT) is a medical diagnostic tool, providing non-invasive, non-radiative and high resolution imaging. OCT has been established since many years in ophthalmology. In dentistry the diagnostic potential of OCT is currently increasingly being noticed. This clinical study includes two individual trials: (i) Longitudinal assessment of surface sealant thickness using optical coherence tomography and (ii) comparison of crevicular fluid levels of inflammatory cytokines after the application of surface ...
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    10. Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule

      Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule
      Purpose : To investigate structural features of the posterior episclera and Tenon's capsule in patients with high myopia. Methods : This hospital-based observational study included highly myopic eyes (myopic refractive error 8 diopters or axial length 26.5 mm) in which the posterior sclera in its full thickness could be visualized on swept-source optical coherence tomography (OCT) images in all 12 radial scans centered on the fovea. We assessed the posterior ...
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    11. Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus | Neurology

      Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus | Neurology
      Purpose: Characterized by a progressive onset of gait disturbances, dementia, and urinary incontinence, idiopathic normal pressure hydrocephalus (iNPH) is considered a rare, but under-diagnosed disease. Non-invasive diagnostic markers are still insufficient to enable the diagnosis of iNPH with certainty and yet early treatment with ventriculoperitoneal (VP) shunting can reverse symptoms and stop disease progression. Vascular circulation abnormalities in iNPH may be reflected by changes in subfoveal and peripapillary choroidal thickness ...
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    12. Features Of Optical Coherence Tomography For The Diagnosis Of Vogt–Koyanagi–Harada Disease

      Features Of Optical Coherence Tomography For The Diagnosis Of Vogt–Koyanagi–Harada Disease
      Background/Purpose: To examine the diagnostic value of optical coherence tomography (OCT) for the detection of acute VogtKoyanagiHarada (VKH) disease. Methods: Clinical charts and OCT images were retrospectively reviewed for patients consecutively diagnosed with acute VKH, subacute VKH, multifocal central serous chorioretinopathy (CSCR), and posterior scleritis. All patients underwent OCT, fundus photography, and fluorescein angiography (FA) before treatment. The characteristics of OCT and FA were analyzed and recorded. Results: The ...
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    13. PERIPAPILLARY ARTERIAL RING OF ZINN-HALLER IN HIGHLY MYOPIC EYES AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      PERIPAPILLARY ARTERIAL RING OF ZINN-HALLER IN HIGHLY MYOPIC EYES AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To visualize the arterial circle of Zinn-Haller (ZHAC) in highly myopic patients by using OCT-A. Methods: Two hundred and fifty-three eyes of 146 consecutive patients with axial length =26.5 mm who underwent OCT-A centered onto the optic disk were studied. Results: Arterial circle of Zinn-Haller was detectable on OCT-A images within the area of the parapapillary myopic conus in 26 (10%) of 253 eyes. The ZHAC was annular ...
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    14. Central Corneal Thickness in Spectral-Domain OCT and Associations with Ocular and Systemic Parameters

      Central Corneal Thickness in Spectral-Domain OCT and Associations with Ocular and Systemic Parameters
      Background . Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods . A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry ...
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    15. Adding Papillomacular Bundle Measurements to Standard Optical Coherence Tomography Does Not Increase Sensitivity to Detect Prior Optic Neuritis in Patients with Multiple Sclerosis

      Adding Papillomacular Bundle Measurements to Standard Optical Coherence Tomography Does Not Increase Sensitivity to Detect Prior Optic Neuritis in Patients with Multiple Sclerosis
      ...rd, full-field visual evoked potentials (VEP). The study protocol was approved by the ethics committee of the University of Heidelberg, Germany (statement S-310/2011) and the study was conducted in accordance with the De...
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    16. Optical Coherence Tomography Angiography of the Foveal Avascular Zone in Retinal Vein Occlusion

      Optical Coherence Tomography Angiography of the Foveal Avascular Zone in Retinal Vein Occlusion
      Purpose: The aim of the study was to visualize and to quantify pathological foveal avascular zone (FAZ) alterations through optical coherence tomography angiography (OCT-A) in eyes with retinal vein occlusion (RVO) in comparison to the unaffected fellow eyes. Procedures: OCT-A was conducted with the Avanti RTVue 100 XR system (Optovue Inc., Fremont, Calif., USA). The borders of the superficial vascular layer (SVL) were defined as 3 m below the internal ...
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  2. About University of Heidelberg

    University of Heidelberg

    University of Heidelberg.  The Ruprecht Karl University of Heidelberg is a public, comprehensive research university located in Heidelberg, Baden-Württemberg, Germany. Commonly referred to as University of Heidelberg, Ruperto Carola, or simply Heidelberg, it is the oldest university in Germany. The University of Heidelberg consists of twelve faculties and offers degree programs at undergraduate, graduate and postdoctoral level in a wide array of disciplines. It is a German Excellence University, and a founding member of the League of European Research Universities, the Coimbra Group, and the European University Association.