1. University of Heidelberg

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    1. Mentioned In 47 Articles

    2. Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule

      Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule
      Purpose : To investigate structural features of the posterior episclera and Tenon's capsule in patients with high myopia. Methods : This hospital-based observational study included highly myopic eyes (myopic refractive error 8 diopters or axial length 26.5 mm) in which the posterior sclera in its full thickness could be visualized on swept-source optical coherence tomography (OCT) images in all 12 radial scans centered on the fovea. We assessed the posterior ...
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    3. Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus | Neurology

      Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus | Neurology
      Purpose: Characterized by a progressive onset of gait disturbances, dementia, and urinary incontinence, idiopathic normal pressure hydrocephalus (iNPH) is considered a rare, but under-diagnosed disease. Non-invasive diagnostic markers are still insufficient to enable the diagnosis of iNPH with certainty and yet early treatment with ventriculoperitoneal (VP) shunting can reverse symptoms and stop disease progression. Vascular circulation abnormalities in iNPH may be reflected by changes in subfoveal and peripapillary choroidal thickness ...
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    4. Features Of Optical Coherence Tomography For The Diagnosis Of Vogt–Koyanagi–Harada Disease

      Features Of Optical Coherence Tomography For The Diagnosis Of Vogt–Koyanagi–Harada Disease
      Background/Purpose: To examine the diagnostic value of optical coherence tomography (OCT) for the detection of acute VogtKoyanagiHarada (VKH) disease. Methods: Clinical charts and OCT images were retrospectively reviewed for patients consecutively diagnosed with acute VKH, subacute VKH, multifocal central serous chorioretinopathy (CSCR), and posterior scleritis. All patients underwent OCT, fundus photography, and fluorescein angiography (FA) before treatment. The characteristics of OCT and FA were analyzed and recorded. Results: The ...
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    5. PERIPAPILLARY ARTERIAL RING OF ZINN-HALLER IN HIGHLY MYOPIC EYES AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      PERIPAPILLARY ARTERIAL RING OF ZINN-HALLER IN HIGHLY MYOPIC EYES AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To visualize the arterial circle of Zinn-Haller (ZHAC) in highly myopic patients by using OCT-A. Methods: Two hundred and fifty-three eyes of 146 consecutive patients with axial length =26.5 mm who underwent OCT-A centered onto the optic disk were studied. Results: Arterial circle of Zinn-Haller was detectable on OCT-A images within the area of the parapapillary myopic conus in 26 (10%) of 253 eyes. The ZHAC was annular ...
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    6. Central Corneal Thickness in Spectral-Domain OCT and Associations with Ocular and Systemic Parameters

      Central Corneal Thickness in Spectral-Domain OCT and Associations with Ocular and Systemic Parameters
      Background . Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods . A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry ...
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    7. Adding Papillomacular Bundle Measurements to Standard Optical Coherence Tomography Does Not Increase Sensitivity to Detect Prior Optic Neuritis in Patients with Multiple Sclerosis

      Adding Papillomacular Bundle Measurements to Standard Optical Coherence Tomography Does Not Increase Sensitivity to Detect Prior Optic Neuritis in Patients with Multiple Sclerosis
      ...rd, full-field visual evoked potentials (VEP). The study protocol was approved by the ethics committee of the University of Heidelberg, Germany (statement S-310/2011) and the study was conducted in accordance with the De...
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    8. Optical Coherence Tomography Angiography of the Foveal Avascular Zone in Retinal Vein Occlusion

      Optical Coherence Tomography Angiography of the Foveal Avascular Zone in Retinal Vein Occlusion
      Purpose: The aim of the study was to visualize and to quantify pathological foveal avascular zone (FAZ) alterations through optical coherence tomography angiography (OCT-A) in eyes with retinal vein occlusion (RVO) in comparison to the unaffected fellow eyes. Procedures: OCT-A was conducted with the Avanti RTVue 100 XR system (Optovue Inc., Fremont, Calif., USA). The borders of the superficial vascular layer (SVL) were defined as 3 m below the internal ...
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    9. FEATURES OF OPTICAL COHERENCE TOMOGRAPHY FOR THE DIAGNOSIS OF VOGT-KOYANAGI-HARADA DISEASE

      FEATURES OF OPTICAL COHERENCE TOMOGRAPHY FOR THE DIAGNOSIS OF VOGT-KOYANAGI-HARADA DISEASE
      Background/Purpose: To examine the diagnostic value of optical coherence tomography (OCT) for the detection of acute Vogt-Koyanagi-Harada (VKH) disease. Methods: Clinical charts and OCT images were retrospectively reviewed for patients consecutively diagnosed with acute VKH, subacute VKH, multifocal central serous chorioretinopathy (CSCR), and posterior scleritis. All patients underwent OCT, fundus photography, and fluorescein angiography (FA) before treatment. The characteristics of OCT and FA were analyzed and recorded. Results: The ...
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    10. Macular Bruch’s Membrane Holes in Choroidal Neovascularization-Related Myopic Macular Atrophy by Swept-Source Optical Coherence Tomography

      Macular Bruch’s Membrane Holes in Choroidal Neovascularization-Related Myopic Macular Atrophy by Swept-Source Optical Coherence Tomography
      Purpose To determine frequency and associations of macular Bruchs membrane defects in the region of macular atrophy developing after the onset of myopic choroidal neovascularization (CNV). Design Retrospective observational case series. Methods The study included all patients who were consecutively examined for high myopia (axial length 26.5mm) and CNV-related macular atrophy in the study period from June to July 2015. The patients underwent a comprehensive ophthalmologic examination including swept-source ...
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    11. Clinical Experience With the First Commercially Available Intraoperative Optical Coherence Tomography System

      Clinical Experience With the First Commercially Available Intraoperative Optical Coherence Tomography System
      BACKGROUND AND OBJECTIVE: A retrospective, single-center case-series was initiated to evaluate initial clinical experience with the first commercially available intraoperative optical coherence tomography system (iOCT). PATIENTS AND METHODS: The Rescan 700 iOCT (Zeiss, Oberkochen, Germany), a spectral-domain OCT system integrated into a surgical microscope, was used in 40 consecutive cases. A standardized review was used to assess whether iOCT imaging resulted in additional information and/or altered decision-making. RESULTS: The ...
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    12. Optical coherence tomography angiography of the foveal avascular zone in diabetic retinopathy

      Optical coherence tomography angiography of the foveal avascular zone in diabetic retinopathy
      Purpose To analyze foveal avascular zone (FAZ) dimensions and symmetry in patients with diabetic retinopathy (DR) compared to healthy controls using optical coherence tomography angiography (OCT angiography). Methods OCT angiography was performed via an Avanti RTVue 100 XR OCT system (Optovue, Inc., Fremont, CA, USA) in patients with diabetes mellitus (DM) and healthy adults. A frame centered on the fovea was used for FAZ measurements. The borders of the superficial ...
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    13. Optical coherence tomography detects structural abnormalities of the nasal mucosa in patients with cystic fibrosis

      Optical coherence tomography detects structural abnormalities of the nasal mucosa in patients with cystic fibrosis
      Background Chronic inflammation and remodeling of the airways remain a hallmark of cystic fibrosis (CF). However, knowledge of the associated mucosal micro-anatomical changes is limited. We evaluated the potential of optical coherence tomography (OCT) for in vivo imaging of the upper airway mucosa in CF patients. Methods A flexible OCT probe was used for cross-sectional imaging of the nasal mucosa in 25 CF patients and 25 healthy controls. Results OCT ...
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    14. Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography

      Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography
      Objective: The aim of this non-interventional study was to characterize retinal layer pathology in Susac syndrome (SuS), a disease with presumably autoimmune-mediated microvessel occlusions in the retina, brain, and inner ear, in comparison to the most important differential diagnosis multiple sclerosis (MS). Methods: Seventeen patients with SuS and 17 age- and sex-matched patients with relapsing-remitting MS (RRMS) and healthy controls (HC) were prospectively investigated by spectral-domain optical coherence tomography (OCT ...
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  2. About University of Heidelberg

    University of Heidelberg

    University of Heidelberg.  The Ruprecht Karl University of Heidelberg is a public, comprehensive research university located in Heidelberg, Baden-Württemberg, Germany. Commonly referred to as University of Heidelberg, Ruperto Carola, or simply Heidelberg, it is the oldest university in Germany. The University of Heidelberg consists of twelve faculties and offers degree programs at undergraduate, graduate and postdoctoral level in a wide array of disciplines. It is a German Excellence University, and a founding member of the League of European Research Universities, the Coimbra Group, and the European University Association.