1. University of Graz

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    1. Mentioned In 29 Articles

    2. The Diagnostic Capability of Swept Source OCT Angiography in Treatment-Naive Exudative Neovascular Age-Related Macular Degeneration

      The Diagnostic Capability of Swept Source OCT Angiography in Treatment-Naive Exudative Neovascular Age-Related Macular Degeneration
      Purpose: To evaluate the capability of swept source-optical coherence tomography angiography (SS-OCTA) in the detection and localization of treatment-naive macular neovascularization (MNV) secondary to exudative neovascular age-related macular degeneration (nAMD). Methods: In this prospective, observational case series, 158 eyes of 142 patients were diagnosed with exudative nAMD using fluorescein (FA) and indocyanine green angiography (ICGA) and evaluated by SS-OCTA in a tertiary retina center (Rudolf Foundation Hospital Vienna, Austria). The ...
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    3. Swept Source-Optical Coherence Tomography Angiography for Management of Secondary Choroidal Neovascularization in Punctate Inner Choroidopathy

      Swept Source-Optical Coherence Tomography Angiography for Management of Secondary Choroidal Neovascularization in Punctate Inner Choroidopathy
      The purpose was to demonstrate the diagnostic and therapeutic feasibility of swept source-optical coherence tomography angiography (SS-OCTA) by picturing neovascular changes secondary to a rare white dot syndrome following long-term intravitreal ranibizumab (IVR). A 28-year-old Caucasian myopic female presented with visual loss in her right eye only. The clinical examination and multimodal imaging including spectral domain (SD)-OCT, blue-peak autofluorescence, fluorescein, and indocyanine green angiography (HRA Spectralis, Heidelberg Engineering; Heidelberg ...
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    4. Deep convolutional neural networks: Outperforming established algorithms in the evaluation of industrial optical coherence tomography (OCT) images of pharmaceutical coatings

      Deep convolutional neural networks: Outperforming established algorithms in the evaluation of industrial optical coherence tomography (OCT) images of pharmaceutical coatings
      This paper presents a novel evaluation approach for optical coherence tomography (OCT) image analysis of pharmaceutical solid dosage forms based on deep convolutional neural networks (CNNs). As a proof of concept, CNNs were applied to image data from both, in- and at-line OCT implementations, monitoring film-coated tablets as well as single- and multi-layered pellets. CNN results were compared against results from established algorithms based on ellipse-fitting, as well as to ...
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    5. Detection rate of diabetic macular microaneurysms comparing dye-based angiography and optical coherence tomography angiography

      Detection rate of diabetic macular microaneurysms comparing dye-based angiography and optical coherence tomography angiography
      Diabetic maculopathy (DM) is a microvascular dysfunction clinically characterized by microaneurysms (MA) leading to edema and central visual deprivation. This prospective explorative study investigated 27 eyes of 17 patients with DM by fluorescein/indocyanine green angiography (FA/ICGA; SPECTRALIS HRA-OCT, Heidelberg Engineering) and by swept source-optical coherence tomography angiography (SS-OCTA; DRI-OCT Triton Plus, Topcon) to identify clinically relevant MAs. The SS-OCTA cubes were split into the superficial capillary plexus (SCP ...
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    6. Comparison of macular neovascularization lesion size by the use of Spectral‐Domain Optical Coherence Tomography Angiography and Swept‐Source Optical Coherence Tomography Angiography versus Indocyanine Green Angiography

      Comparison of macular neovascularization lesion size by the use of Spectral‐Domain Optical Coherence Tomography Angiography and Swept‐Source Optical Coherence Tomography Angiography versus Indocyanine Green Angiography
      Purpose To compare the lesion sizes of macular neovascularization (MNV) imaged with spectral‐domain (SD) and swept‐source (SS) optical coherence tomography angiography (OCTA) as well as indocyanine green angiography (ICGA). Methods In this prospective, observational case series, patients showing a secured diagnosis of MNV on ICGA or Fluorescein Angiography, were imaged by SD‐OCTA and SS‐OCTA on the same day. Lesion size was measured on 3 3‐mm ...
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    7. At-line Validation of Optical Coherence Tomography as In-line/At-line Coating Thickness Measurement Method

      At-line Validation of Optical Coherence Tomography as In-line/At-line Coating Thickness Measurement Method
      Optical Coherence Tomography (OCT) is a promising technology for monitoring of pharmaceutical coating processes. However, the pharmaceutical development and manufacturing require a periodic validation of the sensors accuracy. For this purpose, we propose polyethylene terephthalate (PET) films as a model system, which can be periodically measured during manufacturing coating monitoring via OCT. This study proposes a new approach addressing the method validation requirement in the pharmaceutical industry and presents results ...
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    8. Measurement of granule layer thickness in a spouted bed coating process via optical coherence tomography

      Measurement of granule layer thickness in a spouted bed coating process via optical coherence tomography
      In this work a recently developed in-line measurement technique for monitoring of coating thickness was applied to a spray-coating process in a three-dimensional prismatic spouted bed. The layer thickness was quantified with an optical coherence tomography (OCT) sensor positioned in front of the observation window of the process chamber. The time-dependent layer thickness was measured directly and in real-time from the OCT images, with no chemometric calibration being needed. To ...
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    9. Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration

      Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration
      Purpose . To assess the relationship between signs of activity in exudative neovascular age-related macular degeneration (nAMD) following anti-vascular endothelial growth factor (anti-VEGF) treatment and morphology of choroidal neovascularization (CNV) based on neovascular density as imaged using swept source-optical coherence tomography angiography (SS-OCTA) in a qualitative manner. Methods . A single-cohort retrospective data analysis from one tertiary eye care center. Seventy-seven eyes of 72 patients were included and their charts reviewed which ...
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    10. How to Measure Coating Thickness of Tablets: Method Comparison of Optical Coherence Tomography, Near-infrared Spectroscopy and Weight-, Height- and Diameter Gain

      How to Measure Coating Thickness of Tablets: Method Comparison of Optical Coherence Tomography, Near-infrared Spectroscopy and Weight-, Height- and Diameter Gain
      Film coating of pharmaceutical dosage forms, such as tablets and pellets, can be used to tailor the drug release profile. With that regard, a uniform coating thickness of a single tablet (intra-tablet), all tablets (inter-tablet) and subsequent batches (inter-batch) is crucial. We present a method comparison between in-line (optical coherence tomography and near-infrared spectroscopy) and well-established off-line (height-, weight- and diameter-gain) approaches to determining the coating thickness of tablets. We ...
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    11. Dynamic intraoperative optical coherence tomography for inverted internal limiting membrane flap technique in large macular hole surgery

      Dynamic intraoperative optical coherence tomography for inverted internal limiting membrane flap technique in large macular hole surgery
      Background/objectives To assess the efficacy of dynamic intraoperative spectral-domain optical coherence tomography (iSD-OCT) imaging for inverted internal limiting membrane (ILM) flap technique (IILMFT) in large macular hole (MH) surgery. Subjects/methods Prospective, non-randomized, observational study was conducted on 8 eyes of 7 patients with large, chronic and recurrent MHs, which were treated by pars plana vitrectomy (PPV) with IILMFT. All patients underwent standard pre- and postoperative examination. The iSD-OCT ...
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    12. Influence of optic media of the human eye on the imaging of Argus® II retinal prosthesis with intraoperative spectral-domain optical coherence tomography

      Influence of optic media of the human eye on the imaging of Argus® II retinal prosthesis with intraoperative spectral-domain optical coherence tomography
      Background This study aimed to evaluate the influence of the optic media of the human eye on intraoperative spectral-domain optical coherence tomography (iSD-OCT) of an Argus II retinal prosthesis (AIIRP) during its implantation. Methods One AIIRP was implanted in a human eye with end-stage retinitis pigmentosa and another one in a test eye. Intraoperative imaging was performed using the Rescan 700, a microscope-integrated iSD-OCT system. The feasibility of iSD-OCT imaging ...
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    13. Introduction to swept source optical coherence tomography angiography

      Introduction to swept source optical coherence tomography angiography
      Swept source optical coherence tomography (OCT) technology and OCT-angiography (OCT-A) are two recent developments that have the potential to significantly change our understanding of retinal pathology and retinal vascular pathophysiology. In order to correctly use these technologies to their full diagnostic potential, a thorough understanding of the technology as well as its benefits and limitations is essential. The aim of this review article is to provide an introductory understanding of ...
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    14. 1-15 of 29 1 2 »
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  2. About University of Graz

    University of Graz

    University of Graz is a university located in Graz , Austria , is the largest and oldest university in Styria , as well as the second-largest and second-oldest university in Austria.