1. University of Freiburg

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    1. Mentioned In 23 Articles

    2. Optic Nerve Head Volumetry by Optical Coherence Tomography in Papilledema Related to Idiopathic Intracranial Hypertension

      Optic Nerve Head Volumetry by Optical Coherence Tomography in Papilledema Related to Idiopathic Intracranial Hypertension
      Purpose : Idiopathic intracranial hypertension (IIH) leads to optic nerve head swelling and optic atrophy if left untreated. We wanted to assess an easy to perform volumetric algorithm to detect and quantify papilledema in comparison to retinal nerve fiber layer (RNFL) analysis using optical coherence tomography (OCT). Methods : Participants with and without IIH underwent visual acuity testing at different contrast levels and static perimetry. Spectralis-OCT measurements comprised standard imaging of the ...
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    3. Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas

      Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas
      Purpose : To compare spectral-domain (SD) and swept-source (SS) optical coherence tomography angiography (OCTA) for imaging retinal capillary hemangioblastomas (RCHs) in von Hippel-Lindau disease (VHLD). Methods : Prospective single-center cross-sectional study. Tumor size (TS) of perfused RCHs was assessed clinically in relation to the optic disc size. For both technologies, SD-OCTA and SS-OCTA, corresponding images with a scan size of 3 3 mm 2 and 6 6 mm 2 , respectively, were overlaid ...
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    4. Indications for intraoperative anterior segment optical coherence tomography in corneal surgery

      Indications for intraoperative anterior segment optical coherence tomography in corneal surgery
      Purpose Recently, intraoperative optical coherence tomography (iOCT) has evolved in the field of ophthalmic surgery. So far, the use of iOCT was mainly focused to lamellar keratoplasty, especially deep anterior lamellar keratoplasty (DALK) and Descemet membrane endothelial keratoplasty (DMEK). The aim of this study was to report our experiences with iOCT to introduce new possibilities of this application. Methods We used iOCT in 18 patients who underwent the following surgeries ...
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    5. Swept-source optical coherence tomography angiography alleviates shadowing artifacts caused by subretinal fluid

      Swept-source optical coherence tomography angiography alleviates shadowing artifacts caused by subretinal fluid
      Purpose To characterize the choriocapillaris (CC) structure in relation to subretinal fluid (SRF) as a possible systematic error source using spectral domain (SD-OCTA) compared to swept-source optical coherence tomography angiography (SS-OCTA). Methods This is a prospective case-control study of 23 eyes. Ten patients with acute central serous chorioretinopathy (CSC), three patients with partial macular-off retinal detachment (RD) and ten healthy, age-matched controls were included. Abnormal CC decorrelation signals were quantitatively ...
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    6. Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscop

      Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscop
      Non-muscle-invasive bladder cancer affects millions of people worldwide, resulting in significant discomfort to the patient and potential death. Today, cystoscopy is the gold standard for bladder cancer assessment, using white light endoscopy to detect tumor suspected lesion areas, followed by resection of these areas and subsequent histopathological evaluation. Not only does the pathological examination take days, but due to the invasive nature, the performed biopsy can result in significant harm ...
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    7. Characterisation of vascular changes in different stages of Stargardt disease using double swept-source optical coherence tomography angiography

      Characterisation of vascular changes in different stages of Stargardt disease using double swept-source optical coherence tomography angiography
      Objective To describe vascular changes in different stages of Stargardt disease (STGD) via double swept-source optical coherence tomography angiography. Methods and analysis Prospective, cross-sectional casecontrol study. Twenty-three patients (45 eyes) with ABCA4 mutations graded according to the Fishman STGD classification and 23 controls (23 eyes) were included. Two independent investigators quantified the foveal avascular zone (FAZ) in the superficial and deep capillary plexus (SCP/DCP) and the areas presenting rarefied ...
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    8. Reduction of periodic noise in Fourier domain optical coherence tomography images by frequency domain filtering

      Reduction of periodic noise in Fourier domain optical coherence tomography images by frequency domain filtering
      In Fourier domain optical coherence tomography (FDOCT) coherence noise is caused by interference of light waves back-reflected or scattered from different spots within a measuring depth or from optical components within the OCT system such as a bended optical fibre. This coherence noise appears as periodic stripe patterns along the axial direction in resulting images. Background subtraction and physical segmentation are used to degrade the periodic coherence noise in previous ...
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    9. Value of Optical Coherence Tomography Angiography Imaging in Diagnosis and Treatment of Hemangioblastomas in von Hippel-Lindau Disease

      Value of Optical Coherence Tomography Angiography Imaging in Diagnosis and Treatment of Hemangioblastomas in von Hippel-Lindau Disease
      BACKGROUND AND OBJECTIVE: The introduction of optical coherence tomography angiography (OCTA) provides new insights into the retinal vasculature. The aim of this study was to explore the value of OCTA in imaging retinal hemangioblastomas and monitoring laser treatment in patients with von Hippel-Lindau (VHL) disease. PATIENTS AND METHODS: Ten eyes of 10 patients with VHL disease were included in this retrospective case series. All patients underwent complete ophthalmological work-up including ...
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    10. Quasi-Bessel beams from asymmetric and astigmatic illumination sources

      Quasi-Bessel beams from asymmetric and astigmatic illumination sources
      We study the spatial intensity distribution and the self-reconstruction of quasi-Bessel beams produced from refractive axicon lenses with edge emitting laser diodes as asymmetric and astigmatic illumination sources. Comparing these to a symmetric mono-mode fiber source, we find that the asymmetry results in a transition of a quasi-Bessel beam into a bow-tie shaped pattern and eventually to a line shaped profile at a larger distance along the optical axis. Furthermore ...
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    11. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

      The APOSTEL recommendations for reporting quantitative optical coherence tomography studies
      Objective: To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. Methods: A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several meetings of the coordinating group. Results: We ...
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    12. Bimodal endoscopic probe combining white-light microscopy and optical coherence tomography

      Bimodal endoscopic probe combining white-light microscopy and optical coherence tomography
      We present a novel bimodal endoscopic imaging probe that can simultaneously provide full-field white-light video microscopy and confocal optical coherence tomography (OCT) depth scans. The two modalities rely on spectrally separated optical paths that run partially in parallel through a micro-optical bench system, which has a cross-section of only 2 mm 2.76 mm and is realized via standard silicon micromachining techniques. With a numerical aperture of 0.061, the ...
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    13. Coronal in vivo forward-imaging of rat brain morphology with an ultra-small optical coherence tomography fiber probe

      Coronal in vivo forward-imaging of rat brain morphology with an ultra-small optical coherence tomography fiber probe
      A well-established navigation method is one of the key conditions for successful brain surgery: it should be accurate, safe and online operable. Recent research shows that optical coherence tomography (OCT) is a potential solution for this application by providing a high resolution and small probe dimension. In this study a fiber-based spectral-domain OCT system utilizing a super-luminescent-diode with the center wavelength of 840 nm providing 14.5 m axial resolution ...
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    14. A Tunable Optofluidic Silicon Optical Bench

      A Tunable Optofluidic Silicon Optical Bench
      A miniaturized optical bench, based on silicon micromachining and with high modularity and flexibility, is presented. This optical microsystem integrates optics, fluidics, high-precision mechanics, and focal length tunable lenses and allows the realization of numerous optical arrangements, such as telephoto and retrofocus systems. Due to its dimensions, the technology may be used for designing a variety of endoscopic imaging probes, including those for optical coherence tomography. As the measuring beam ...
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    15. 1-15 of 23 1 2 »
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  2. About University of Freiburg

    University of Freiburg

    University of Freiburg was founded 1457 is one of the oldest universities in Germany, it has a long tradition of teaching the humanities, social sciences and natural sciences. The university is one of Germany's most prestigious and a leading research and teaching institution in Europe. The University of Freiburg was designated a German "University of Excellence" in 2007. Institute of Microsystem Technology (IMTEK) at the University of Freiburg is unique in Europe. The scientific scope of the institute, with 18 faculty and over 200 research and technical staff, encompasses nearly all technical fields relevant to the highly interdisciplinary world of microsystem technology. Through the depth and range of our activities, we are one of the internationally leading academic research departments in this dynamic and innovative field.