1. University of Erlangen

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    1. Mentioned In 85 Articles

    2. In-Process Analysis of Melt Pool Fluctuations with Scanning Optical Coherence Tomography for Laser Welding of Copper for Quality Monitoring

      In-Process Analysis of Melt Pool Fluctuations with Scanning Optical Coherence Tomography for Laser Welding of Copper for Quality Monitoring
      Optical coherence tomography (OCT) is an inline process monitoring technology for laser welding with various applications in the pre-, in-, and post-process. In-process monitoring with OCT focuses on the measurement of weld depth by the placement of a singular measurement beam into the keyhole. A laterally scanned measurement beam gives the opportunity to measure the keyhole and melt pool width. The processing region can be identified by separating higher signal ...
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    3. Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide

      Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide
      We report a novel technique to overcome the depth-of-focus limitation in optical coherence tomography using chromatic dispersion of zinc selenide lens. Optical coherence tomography is an established method of optical imaging, which found numerous biomedical applications. However, the depth scanning range of high-resolution optical coherence tomography is limited by its depth of focus. Chromatic dispersion of zinc selenide lens allows to get high lateral resolution along extended depth of focus ...
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    4. Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles

      Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles
      Label-free detection of nanoparticles is essential for a thorough evaluation of their cellular effects. In particular, nanoparticles intended for medical applications must be carefully analyzed in terms of their interactions with cells, tissues, and organs. Since the labeling causes a strong change in the physicochemical properties and thus also alters the interactions of the particles with the surrounding tissue, the use of fluorescently labeled particles is inadequate to characterize the ...
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    5. Clinical presentation does not affect acute mechanical performance of the Novolimus-eluting bioresorbable vascular scaffold as assessed by optical coherence tomography

      Clinical presentation does not affect acute mechanical performance of the Novolimus-eluting bioresorbable vascular scaffold as assessed by optical coherence tomography
      Introduction: Initial trials of bioresorbable vascular scaffolds (BVS) have mostly excluded patients presenting with acute coronary syndrome (ACS). However, these patients might benefit from a BVS platform, in particular as they are often younger and have been less frequently treated than patients with chronic disease. Aim: To compare the acute performance of a Novolimus eluting BVS in ACS and non-ACS patients using optical coherence tomography (OCT) in patients presenting with ...
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    6. Portable Optical Coherence Elastography System With Flexible and Phase Stable Common Path Optical Fiber Probe

      Portable Optical Coherence Elastography System With Flexible and Phase Stable Common Path Optical Fiber Probe
      Biomechanical properties drive the functioning of cells and tissue. Measurement of such properties in the clinic is quite challenging, however. Optical coherence elastography is an emerging technique in this field that can measure the biomechanical properties of the tissue. Unfortunately, such systems have been limited to benchtop configuration with limited clinical applications. A truly portable system with a flexible probe that could probe different sample sites with ease is still ...
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    7. Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography

      Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography
      Purpose: To quantify retinal vasculature changes in Stargardt disease1 with volume-rendered optical coherence tomography angiography (OCTA). Methods: OCTA volumes from heathy subjects and two subgroups of STGD1 patients with the presence/absence of definitely decreased autofluorescence (DDAF) areas were compared. OCTA vessel surface area (VSA) and vessel volume (VV) were measured in central zones (Z) of 1, 2 and 3mm diameter. Results: 29 eyes of 15 STGD1 patients (20/9 ...
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    8. Efficient and high accuracy 3-D OCT angiography motion correction in pathology

      Efficient and high accuracy 3-D OCT angiography motion correction in pathology
      We describe a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features such as retinal layers as well as transverse angiographic vascular features in a joint optimization. Combined with orthogonal scanning and favorization of kinematically more plausible displacements, subpixel alignment and micrometer-scale distortion correction is achieved in all 3 dimensions. As no specific ...
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    9. Maximum A Posteriori Signal Recovery for Optical Coherence Tomography Angiography Image Generation and Denoising

      Maximum A Posteriori Signal Recovery for Optical Coherence Tomography Angiography Image Generation and Denoising
      Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed over time and used to compute OCTA image data. OCTA data are prone to noise and artifacts caused by variations in flow speed and patientmovement. We propose a novel iterativemaximuma posteriori signal recovery algorithm in order to generate OCTA ...
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    10. N2NSR‐OCT: Simultaneous denoising and super‐resolution in optical coherence tomography images using semi‐supervised deep learning

      N2NSR‐OCT: Simultaneous denoising and super‐resolution in optical coherence tomography images using semi‐supervised deep learning
      Optical coherence tomography (OCT) imaging shows a significant potential in clinical routines due to its noninvasive property. However, the quality of OCT images is generally limited by inherent speckle noise of OCT imaging and low sampling rate. To obtain high signal‐to‐noise ratio (SNR) and high‐resolution (HR) OCT images within a short scanning time, we presented a learning‐based method to recover high‐quality OCT images from noisy ...
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    11. Retinal choroidal vessel imaging based on multi-wavelength fundus imaging with the guidance of optical coherence tomography

      Retinal choroidal vessel imaging based on multi-wavelength fundus imaging with the guidance of optical coherence tomography
      A multispectral fundus camera (MSFC), as a novel noninvasive technology, uses an extensive range of monochromatic light sources that enable the view of different sectional planes of the retinal and choroidal structures. However, MSFC imaging involves complex processes affected by various factors, and the recognized theory based on light absorption above the choroid is not sufficient. In an attempt to supplement the relevant explanations, in this study, we used optical ...
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    12. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

      Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
      Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to Doppler and other phase-based approaches. However, the high axial resolution of OCT makes it very sensitive to the pulsatile bulk motion noise in the axial direction. To overcome this limitation, we developed split-spectrum amplitude-decorrelation angiography (SSADA) to improve the signal-to-noise ratio (SNR) of flow detection. The full OCT spectrum was split into several narrower ...
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    13. Novel input polarisation independent endoscopic cross polarised optical coherence tomography probe

      Novel input polarisation independent endoscopic cross polarised optical coherence tomography probe
      Lead by the original idea to perform noninvasive optical biopsies of various tissue, optical coherence tomography found numerous medical applications within the last two decades. The interference based imaging technique opens the possibility to visualise subcellular morphology up to an imaging depth of 3mm and up to micron level axial and lateral resolution. The birefringence properties of the tissue are visualised with enhanced contrast using polarisation sensitive or cross polarised ...
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    14. Optical Coherence Tomography with an SU(1,1) interferometer in the high parametric gain regime

      Optical Coherence Tomography with an SU(1,1) interferometer in the high parametric gain regime
      Gerard J. Machado,1, a) Gaetano Frascella,2, 3 Juan P. Torres,1, 4 and Maria V. Chekhova We demonstrate optical coherence tomography based on an SU(1,1) nonlinear interferometer with high-gain parametric down-conversion. For imaging and sensing applications, this scheme promises to outperform previous experiments working at low parametric gain, since higher photon fluxes provide better sensitivity and lower integration times for obtaining high-quality images. Moreover, there is ...
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    15. Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation

      Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation
      Optical coherence tomography (OCT) is a commonly used ophthalmic imaging modality. While OCT has traditionally been viewed cross-sectionally (i.e., as a sequence of B-scans), higher A-scan rates have increased interest in en face OCT visualization and analysis. The recent clinical introduction of OCT angiography (OCTA) has further spurred this interest, with chorioretinal OCTA being predominantly displayed via en face projections. Although en face visualization and quantitation are natural for ...
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    16. Input polarization-independent polarization-sensitive optical coherence tomography using a depolarizer

      Input polarization-independent polarization-sensitive optical coherence tomography using a depolarizer
      Polarization-sensitive optical coherence tomography is gaining attention because of its ability to diagnose certain pathological conditions at an early stage. The majority of polarization-sensitive optical coherence tomography systems require a polarization controller and a polarizer to obtain the optimal polarization state of the light at the sample. Such systems are prone to misalignment since any movement of the optical fiber normally coupled to the light source will change the polarization ...
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    17. 1-15 of 85 1 2 3 4 5 6 »
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  2. About University of Erlangen

    University of Erlangen

    University of Erlangen: Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) is one of the largest universities in Germany. With its five faculties, FAU offers an almost unique scope of subjects ranging from the Humanities to Law and Economics as well as Sciences, Medicine and Engineering. The close collaboration between the single disciplines is reflected by the University’s Mission Statement "Advance through Networks". FAU thus offers perfect conditions for interdisciplinary research and learning to students and scientists alike.