1. University of Cyprus

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    1. Mentioned In 21 Articles

    2. Dual-angle optical coherence tomography for index of refraction estimation using rigid registration and cross-correlation

      Dual-angle optical coherence tomography for index of refraction estimation using rigid registration and cross-correlation
      The index of refraction ( n ) of materials and/or tissues depends on their physical properties and serves as a source of optical contrast in imaging. The variations of the index of refraction have also been investigated for diagnostic purposes in various fields, such as hematology, oncology, etc., since they can signify disease and cell dynamic changes. Optical coherence tomography (OCT) has been used in the past to measure the index ...
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    3. Comparison of tissue dispersion measurement techniques based on optical coherence tomography

      Comparison of tissue dispersion measurement techniques based on optical coherence tomography
      The effects of dispersion on optical coherence tomography (OCT) images have long been documented. The imbalance of spectral broadening, caused by dispersion mismatches in the two arms of the OCT interferometer, can result in significant resolution degradation. Efforts to correct this phenomenon have resulted in improved image quality using various techniques. However, dispersion is also present and varies in tissues. As a result, group velocity dispersion (GVD) can be used ...
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    4. Automated detection of esophageal dysplasia in in vivo optical coherence tomography images of the human esophagus

      Automated detection of esophageal dysplasia in in vivo optical coherence tomography images of the human esophagus
      Catheter-based Optical Coherence Tomography (OCT) devices allow real-time and comprehensive imaging of the human esophagus. Hence, they provide the potential to overcome some of the limitations of endoscopy and biopsy, allowing earlier diagnosis and better prognosis for esophageal adenocarcinoma patients. However, the large number of images produced during every scan makes manual evaluation of the data exceedingly difficult. In this study, we propose a fully automated tissue characterization algorithm, capable ...
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    5. Using speckle to measure tissue dispersion in optical coherence tomography

      Using speckle to measure tissue dispersion in optical coherence tomography
      Tissue dispersion could be used as a marker of early disease changes to further improve the diagnostic potential of optical coherence tomography (OCT). However, most methods to measure dispersion, described in the literature, rely on the presence of distinct and strong reflectors and are, therefore, rarely applicable in vivo . A novel technique has been developed which estimates the dispersion-induced resolution degradation from the image speckle and, as such, is applicable ...
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    6. Tissue dispersion measurement techniques using optical coherence tomography

      Tissue dispersion measurement techniques using optical coherence tomography
      Dispersion, a result of wavelength-dependent index of refraction variations, causes pulse-width broadening with detrimental effects in many pulsed-laser applications. It is also considered to be one of the major causes of resolution degradation in Optical Coherence Tomography (OCT). However, dispersion is material dependent and, in tissue, Group Velocity Dispersion (GVD) could be used, for example, to detect changes associated with early cancer and result in more accurate disease diagnosis. In ...
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    7. Using speckle to measure tissue dispersion in optical coherence tomography

      Using speckle to measure tissue dispersion in optical coherence tomography
      In Optical Coherence tomography (OCT), dispersion mismatches cause degradation of the image resolution. However, dispersion is specific to the material that is causing the effect and can therefore carry useful information regarding the composition of the samples. In this summary, we propose a novel technique for estimating the dispersion in tissue which uses the image speckle to calculate the PSF degradation and is therefore applicable to any tissue and can ...
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    8. Lateral resolution improvement of oversampled OCT images using Capon estimation of weighted subvolume contribution

      Lateral resolution improvement of oversampled OCT images using Capon estimation of weighted subvolume contribution
      A novel technique for lateral resolution improvement in optical coherence tomography (OCT) is presented. The proposed method is based on lateral oversampling of the image. The locations and weights of multiple high spatial resolution sub-volumes are calculated using a Capon estimator assuming each contributes a weighted portion to the detected signal. This technique is independent of the delivery optics and the depth of field. Experimental results demonstrate that it is ...
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    9. Correlation of the derivative as a robust estimator of scatterer size in optical coherence tomography (OCT)

      Correlation of the derivative as a robust estimator of scatterer size in optical coherence tomography (OCT)
      The size-dependent spectral variations, predicted by Mie theory, have already been considered as a contrast enhancement mechanism in optical coherence tomography. In this work, a new spectroscopic metric, the bandwidth of the correlation of the derivative, was developed for estimating scatterer size which is more robust and accurate compared to existing methods. Its feasibility was demonstrated using phantoms containing polystyrene microspheres as well as images of normal and cancerous human ...
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    10. Development of a new, robust and accurate, spectroscopic metric for scatterer size estimation in optical coherence tomography (OCT) images

      Development of a new, robust and accurate, spectroscopic metric for scatterer size estimation in optical coherence tomography (OCT) images
      The modulations appearing on the backscattering spectrum originating from a scatterer are related to its diameter as described by Mie theory for spherical particles. Many metrics for Spectroscopic Optical Coherence Tomography (SOCT) take advantage of this observation in order to enhance the contrast of Optical Coherence Tomography (OCT) images. However, none of these metrics has achieved high accuracy when calculating the scatterer size. In this work, Mie theory was used ...
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    11. Estimation of weighted multi-scatterer contributions for improvement of lateral resolution of optical coherence tomography images

      Estimation of weighted multi-scatterer contributions for improvement of lateral resolution of optical coherence tomography images
      A method for improvement of lateral resolution in Optical Coherence Tomography (OCT) is presented. The resolution improvement achieved with this method does not depend on the delivery optics. Moreover the depth of focus is not restricted. The method is based on the lateral oversampling of the image. The laterally oversampled signals are backscattered signals from shifted and overlapped resolution volumes. Signals from successive volumes are correlated due to the region ...
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    12. Lateral resolution improvement in Optical Coherence Tomography (OCT) images

      Lateral resolution improvement in Optical Coherence Tomography (OCT) images
      A novel method for lateral resolution improvement of Optical Coherence Tomography (OCT) images, which is independent of the focusing of the delivery optics and the depth of field, is presented. This method was inspired by radar range oversampling techniques. It is based on the lateral oversampling of the image and the estimation of the locations of the multiple scatterers which contribute to the signal. The information in the oversampled images ...
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    13. University of Cyprus receives a grant of 163,780 Euro ($208,844) enhancing the resolution of Optical Coherence Tomography.

      University of Cyprus receives a grant of 163,780 Euro ($208,844) enhancing the resolution of Optical Coherence Tomography.
      ...The proposed research will be performed in the Biomedical Imaging and Applied Optics (BIAO) Laboratory of the University of Cyprus. The partners are the National Technical University of Athens (NTUA) through the Institut...
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    14. Axial resolution improvement by modulated deconvolution in Fourier domain optical coherence tomography

      Axial resolution improvement by modulated deconvolution in Fourier domain optical coherence tomography
      A novel technique for axial resolution improvement in Fourier domain optical coherence tomography (FDOCT) is presented. The technique is based on the deconvolution of modulated optical coherence tomography signals. In FDOCT, the real part of the Fourier transform of the interferogram is modulated by a frequency which depends on the position of the interferogram in k space. A slight numerical k shift results in a different modulation frequency. By adding ...
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    15. Lateral resolution improvement in oversampled Optical Coherence Tomography images assuming weighted oversampled multi-scatterer contributions

      Lateral resolution improvement in oversampled Optical Coherence Tomography images assuming weighted oversampled multi-scatterer contributions
      A novel method for lateral resolution improvement of Optical Coherence Tomography (OCT) images, which is independent of the focusing of the delivery optics and the depth of field, is presented. This method was inspired by radar range oversampling techniques. It is based on the lateral oversampling of the image and the estimation of the locations of the multiple scatterers which contribute to the signal. The information in the oversampled images ...
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    16. Handbook of Biomedical Optics (Book)

      Handbook of Biomedical Optics (Book)
      Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamentals of each subject, ensuring accessibility to a wide multidisciplinary readership. It also offers a view of the state of the art and discusses advantages and ...
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    17. 1-15 of 21 1 2 »
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  2. About University of Cyprus

    University of Cyprus

    University of Cyprus aims to become a leadind educational and research institution that will distinguish itself internationally through the promotion of scolarship. It is already recognized as a centre of excellence in the Mediterranean region. The main objectives of the University are twofold: the promotion of scholarship and education through teaching and research, and the enhancement of the cultural, social and economic development of Cyprus.  In this context, the University believes that education must provide more than simply accumulation of knowledge.It must also encourage students’ active participation in the process of learning and acquisition of those values necessary for responsible involvement in the community. The University sets high standards for all branches of scholarship. Research is promoted and funded in all departments for its contribution to scholarship in general and for its local and international applications.