1. University of Copenhagen

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    1. Mentioned In 133 Articles

    2. Potential of contrast agents to enhance in vivo confocal microscopy and optical coherence tomography in dermatology: A review

      Potential of contrast agents to enhance in vivo confocal microscopy and optical coherence tomography in dermatology: A review
      Distinction between normal skin and pathology can be a diagnostic challenge. This systematic review summarizes how various contrast agents, either topically delivered, or injected into the skin affect distinction between skin disease and normal skin when imaged by optical coherence tomography (OCT) and confocal microscopy (CM). A systematic review of in vivo OCT and CM studies using exogenous contrast agents on healthy human skin or skin disease was performed. In ...
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    3. Transfollicular delivery of gold microparticles in healthy skin and acne vulgaris, assessed by in vivo reflectance confocal microscopy and optical coherence tomography

      Transfollicular delivery of gold microparticles in healthy skin and acne vulgaris, assessed by in vivo reflectance confocal microscopy and optical coherence tomography
      Introduction Topical application of gold microparticles (GMPs) for selective photothermolysis is a recently FDA‐cleared therapy for acne vulgaris. Current evidence indicates the potential of optical imaging to non‐invasively visualize GMPs and describe photothermal tissue effects. Objectives To qualitatively and quantitatively describe GMP delivery in vivo and visualize laser‐mediated thermal effects of GMPs in facial skin of acne patients and healthy participants, using reflectance confocal microscopy (RCM) and ...
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    4. Microscale light management and inherent optical properties of intact corals studied with optical coherence tomography

      Microscale light management and inherent optical properties of intact corals studied with optical coherence tomography
      Coral reefs are highly productive photosynthetic systems and coral optics studies suggest that such high efficiency is due to optimized light scattering by coral tissue and skeleton. Here, we characterize the inherent optical properties, i.e. the scattering coefficient, s , and the anisotropy of scattering, g , of eight intact coral species using optical coherence tomography (OCT). Specifically, we describe light scattering by coral skeletons, coenoarc tissues, polyp tentacles and areas ...
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    5. Microneedle fractional radiofrequency‐induced micropores evaluated by in vivo reflectance confocal microscopy, optical coherence tomography, and histology

      Microneedle fractional radiofrequency‐induced micropores evaluated by in vivo reflectance confocal microscopy, optical coherence tomography, and histology
      Background Microneedle fractional radiofrequency (MNRF) is a minimally invasive technique that delivers radiofrequency (RF) energy into the skin via microneedles. Reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) enable the characterization of device‐tissue interactions in in vivo skin. The aim of this study is to describe MNRF‐induced micropores using RCM and OCT imaging. Materials and methods Five healthy participants were treated with a 7 7 array of ...
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    6. Changes in Coronary Plaque Composition in Patients With Acute Myocardial Infarction Treated With High-Intensity Statin Therapy (IBIS-4): A Serial Optical Coherence Tomography Study

      Changes in Coronary Plaque Composition in Patients With Acute Myocardial Infarction Treated With High-Intensity Statin Therapy (IBIS-4): A Serial Optical Coherence Tomography Study
      Objectives This study assessed changes in optical coherence tomography (OCT)-defined plaque composition in patients with ST-elevation myocardial infarction (STEMI) receiving high-intensity statin treatment. Background OCT is a high-resolution modality capable of measuring plaque characteristics including fibrous cap thickness (FCT) and macrophage infiltration. There is limited in vivo evidence regarding the effects of statins on OCT-defined coronary atheroma composition and no evidence in the context of STEMI. Methods In the ...
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    7. Michelson Diagnostics: Imaging Reveals Changes in Blood Vessel Growth in Deadly Melanoma Skin Cance

      Michelson Diagnostics: Imaging Reveals Changes in Blood Vessel Growth in Deadly Melanoma Skin Cance
      ... four leading European dermatology groups (University of Modena and Reggio Emilia, General Hospital Augsburg, University of Copenhagen and Collegium Medicum Berlin). The device used was Michelson Diagnostics 'VivoSight O...
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    8. The vascular morphology of melanoma is related to Breslow index: an in vivo study with dynamic optical coherence tomography

      The vascular morphology of melanoma is related to Breslow index: an in vivo study with dynamic optical coherence tomography
      Background Malignant melanoma is an aggressive skin cancer, which can lead to metastasis development. Vascularization enhancement is fundamental for tumor growth, worsening the prognosis. Dynamic Optical Coherence Tomography (D‐OCT) enables the in vivo evaluation of vascular patterns in skin lesions. Objective In vivo evaluation of the melanoma vessel morphology by means of D‐OCT and correlation with Breslow index. Methods Retrospective analysis of histologically proven melanomas, evaluated by D ...
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    9. Dynamic optical coherence tomography of histamine induced wheals

      Dynamic optical coherence tomography of histamine induced wheals
      Background Dynamic optical coherence tomography (D‐OCT) is a noninvasive imaging technique providing images of the skin and detecting movement in the tissue ie, measuring blood flow. The attenuation coefficient describes light absorption and scattering abilities of the tissue, while the dynamic signal provides a quantitative measure of the blood flow. Aim The study objective is to describe the dynamic changes of the skin and skin vessels during histamine release ...
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    10. Advances in optical coherence tomography in dermatology—a review

      Advances in optical coherence tomography in dermatology—a review
      Optical coherence tomography (OCT) was introduced as an imaging system, but like ultrasonography, other measures, such as blood perfusion and polarization of light, have enabled the technology to approach clinical utility. This review aims at providing an overview of the advances in clinical research based on the improving technical aspects. OCT provides cross-sectional and en face images down to skin depths of 0.4 to 2.00 mm with optical ...
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    11. Two optical coherence tomography systems detect topical gold nanoshells in hair follicles, sweat ducts and measure epidermis

      Two optical coherence tomography systems detect topical gold nanoshells in hair follicles, sweat ducts and measure epidermis
      Optical coherence tomography (OCT) is an optical imaging technology that enables real time, high‐resolution, cross‐sectional and en face investigation of skin by detecting reflected broad‐spectrum near‐infrared light from tissue. OCT provides micron‐scale spatial resolution and millimeter‐scale depth of penetration [1]. Several commercial OCT systems with handheld probes targeted for Dermatology are now available [2].
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    12. Optical Coherence Tomography Angiography of Purtscher Retinopathy after Severe Traffic Accident in 16-Year-Old Boy

      Optical Coherence Tomography Angiography of Purtscher Retinopathy after Severe Traffic Accident in 16-Year-Old Boy
      Purpose . To describe optical coherence tomography (OCT) angiography (OCTA) in a case of Purtscher retinopathy. Methods . A 16-year-old male underwent ophthalmological examination including color fundus photography, spectral domain OCT, OCTA, and microperimetry. Examination was performed 10 days, 1 month, and 6 months after the trauma. Diagnosis was based on the characteristic clinical presentation. Patients . A single patient case. Results . Only the right eye was affected, and all examinations of the ...
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  2. About University of Copenhagen

    University of Copenhagen

    The University of Copenhagen is the oldest and largest university and research institution in Denmark. Founded in 1479, it has more than 37,000 students, a majority of whom are female (59%), and more than 7,000 employees. The University has several campuses located in and around Copenhagen, with the oldest located in central Copenhagen. Most courses are taught in Danish; however, more and more courses are offered in English and some in German. The University is a member of the International Alliance of Research Universities (IARU).