1. University of Copenhagen

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    1. Mentioned In 143 Articles

    2. Predictive value of optical coherence tomography, multifocal visual evoked potentials, and full-field visual evoked potentials of the fellow, non-symptomatic eye for subsequent multiple sclerosis development in patients with acute optic neuritis

      Predictive value of optical coherence tomography, multifocal visual evoked potentials, and full-field visual evoked potentials of the fellow, non-symptomatic eye for subsequent multiple sclerosis development in patients with acute optic neuritis
      Background: Diagnosis of multiple sclerosis (MS) may sometimes be ascertained at the time of optic neuritis (ON) but other times require the advent of new disease activity. Objectives: The aim of this study was to examine the predictive value of optical coherence tomography (OCT) and visual evoked potential (VEP) measurements of the non-symptomatic, fellow eye of ON patients, for conversion to MS. Methods: This is a prospective cohort study in ...
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    3. An open-source robotic platform that enables automated monitoring of replicate biofilm cultivations using optical coherence tomography

      An open-source robotic platform that enables automated monitoring of replicate biofilm cultivations using optical coherence tomography
      The paper introduces a fully automated cultivation and monitoring tool to study biofilm development in replicate experiments operated in parallel. To gain a fundamental understanding of the relation between cultivation conditions and biofilm characteristics (e.g., structural, mechanical) a monitoring setup allowing for the standardization of methods is required. Optical coherence tomography (OCT) is an imaging modality ideal for biofilms since it allows for the monitoring of structure in real ...
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    4. Utility of Multimodality Intravascular Imaging and the Local Hemodynamic Forces to Predict Atherosclerotic Disease Progression

      Utility of Multimodality Intravascular Imaging and the Local Hemodynamic Forces to Predict Atherosclerotic Disease Progression
      Objectives This study sought to examine the utility of multimodality intravascular imaging and of the endothelial shear stress (ESS) distribution to predict atherosclerotic evolution. Background There is robust evidence that intravascular ultrasound (IVUS)-derived plaque characteristics and ESS distribution can predict, with however limited accuracy, atherosclerotic evolution; nevertheless, it is yet unclear whether multimodality imaging and ESS mapping enable more accurate prediction of coronary plaque progression. Methods A total of ...
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    5. Migration of an outer retinal element in a healthy child followed by longitudinal multimodal imaging

      Migration of an outer retinal element in a healthy child followed by longitudinal multimodal imaging
      Purpose To describe the migration of an outer retinal element using longitudinal multimodal imaging. Observations In the retina of a healthy 7-year-old girl, movement of a hyperreflective element of 15 m extent was seen using optical coherence tomography (OCT), confocal scanning laser ophthalmoscopy (cSLO), and adaptive optics fundus photography (AO). On the OCT B-scan, the element initially appeared at the level of the outer limiting membrane with an umbra reaching ...
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    6. Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscop

      Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscop
      Non-muscle-invasive bladder cancer affects millions of people worldwide, resulting in significant discomfort to the patient and potential death. Today, cystoscopy is the gold standard for bladder cancer assessment, using white light endoscopy to detect tumor suspected lesion areas, followed by resection of these areas and subsequent histopathological evaluation. Not only does the pathological examination take days, but due to the invasive nature, the performed biopsy can result in significant harm ...
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    7. Optical coherence tomography of onychomycosis: proposed terminology and a suggestion of practical usage

      Optical coherence tomography of onychomycosis: proposed terminology and a suggestion of practical usage
      Onychomycosis is the most common cause of nail changes accounting for about half of all nail diseases. It is important to diagnose the fungal pathogen to prescribe adequate treatment, but as genus- and species-specific diagnostic tests can be time consuming and expensive, it is crucial to obtain representative tissue during nail scrapings. Optical coherence tomography (OCT) is a non-invasive imaging tool enabling real-time imaging of skin and tissue. Pilot studies ...
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    8. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent
      This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular ...
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    9. Basal cell carcinoma treated with combined ablative fractional laser and ingenol mebutate – An exploratory study monitored by optical coherence tomography and reflectance confocal microscopy

      Basal cell carcinoma treated with combined ablative fractional laser and ingenol mebutate – An exploratory study monitored by optical coherence tomography and reflectance confocal microscopy
      Background Basal cell carcinomas (BCCs) have previously been treated off‐label with ingenol mebutate (IM). Ablative fractional laser (AFL) may improve efficacy of IM by increasing drug uptake in the tumor. Optical coherence tomography (OCT) and reflectance confocal microscopy (RCM) detect BCC non‐invasively. Our aim was to investigate BCC response and tolerability after combined AFL and IM treatment of low‐risk BCCs. Methods Twenty patients with histologically verified superficial ...
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    10. Potential of contrast agents to enhance in vivo confocal microscopy and optical coherence tomography in dermatology: A review

      Potential of contrast agents to enhance in vivo confocal microscopy and optical coherence tomography in dermatology: A review
      Distinction between normal skin and pathology can be a diagnostic challenge. This systematic review summarizes how various contrast agents, either topically delivered, or injected into the skin affect distinction between skin disease and normal skin when imaged by optical coherence tomography (OCT) and confocal microscopy (CM). A systematic review of in vivo OCT and CM studies using exogenous contrast agents on healthy human skin or skin disease was performed. In ...
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    11. Transfollicular delivery of gold microparticles in healthy skin and acne vulgaris, assessed by in vivo reflectance confocal microscopy and optical coherence tomography

      Transfollicular delivery of gold microparticles in healthy skin and acne vulgaris, assessed by in vivo reflectance confocal microscopy and optical coherence tomography
      Introduction Topical application of gold microparticles (GMPs) for selective photothermolysis is a recently FDA‐cleared therapy for acne vulgaris. Current evidence indicates the potential of optical imaging to non‐invasively visualize GMPs and describe photothermal tissue effects. Objectives To qualitatively and quantitatively describe GMP delivery in vivo and visualize laser‐mediated thermal effects of GMPs in facial skin of acne patients and healthy participants, using reflectance confocal microscopy (RCM) and ...
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    12. Microscale light management and inherent optical properties of intact corals studied with optical coherence tomography

      Microscale light management and inherent optical properties of intact corals studied with optical coherence tomography
      Coral reefs are highly productive photosynthetic systems and coral optics studies suggest that such high efficiency is due to optimized light scattering by coral tissue and skeleton. Here, we characterize the inherent optical properties, i.e. the scattering coefficient, s , and the anisotropy of scattering, g , of eight intact coral species using optical coherence tomography (OCT). Specifically, we describe light scattering by coral skeletons, coenoarc tissues, polyp tentacles and areas ...
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    13. Microneedle fractional radiofrequency‐induced micropores evaluated by in vivo reflectance confocal microscopy, optical coherence tomography, and histology

      Microneedle fractional radiofrequency‐induced micropores evaluated by in vivo reflectance confocal microscopy, optical coherence tomography, and histology
      Background Microneedle fractional radiofrequency (MNRF) is a minimally invasive technique that delivers radiofrequency (RF) energy into the skin via microneedles. Reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) enable the characterization of device‐tissue interactions in in vivo skin. The aim of this study is to describe MNRF‐induced micropores using RCM and OCT imaging. Materials and methods Five healthy participants were treated with a 7 7 array of ...
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  2. About University of Copenhagen

    University of Copenhagen

    The University of Copenhagen is the oldest and largest university and research institution in Denmark. Founded in 1479, it has more than 37,000 students, a majority of whom are female (59%), and more than 7,000 employees. The University has several campuses located in and around Copenhagen, with the oldest located in central Copenhagen. Most courses are taught in Danish; however, more and more courses are offered in English and some in German. The University is a member of the International Alliance of Research Universities (IARU).