1. University of Connecticut

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    1. Mentioned In 41 Articles

    2. Dynamic Optical Coherence Tomography of Cutaneous Blood Vessels in Melasma and Vessel Response to Oral Tranexamic Acid

      Dynamic Optical Coherence Tomography of Cutaneous Blood Vessels in Melasma and Vessel Response to Oral Tranexamic Acid
      Background and objectives: Melasma may be related to aberrant blood vessels, but there has been no report on the utility of dynamic optical coherence tomography (D-OCT) in studying vessel characteristics in melasma. We studied the characteristics of cutaneous blood vessels in melasma and the effects of oral tranexamic acid (TXA) with D-OCT. Study design/materials and methods: Six patients with moderate to severe melasma had a D-OCT scanning of the ...
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    3. Deep learning classifier with optical coherence tomography images for early dental caries detection

      Deep learning classifier with optical coherence tomography images for early dental caries detection
      Dental caries is a microbial disease that results in localized dissolution of the mineral content of dental tissue. Despite considerable decline in the incidence of dental caries, it remains a major health problem in many societies. Early detection of incipient lesions at initial stages of demineralization can result in the implementation of non-surgical preventive approaches to reverse the demineralization process. In this paper, we present a novel approach combining deep ...
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    4. Classification of human ovarian tissue using full field optical coherence tomography

      Classification of human ovarian tissue using full field optical coherence tomography
      The feasibility of a full-field optical coherence tomography (FFOCT) system for rapid wide field optical analysis of normal and malignant human ovarian tissue pathologies was demonstrated. Five features were extracted from the normalized image histogram from 56 FFOCT images, based on the differences in the morphology of the normal and malignant tissue samples.
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    5. Characterization of human oral tissues based on quantitative analysis of optical coherence tomography images

      Characterization of human oral tissues based on quantitative analysis of optical coherence tomography images
      In this paper, five types of tissues, human enamel, human cortical bone, human trabecular bone, muscular tissue, and fatty tissue were imaged ex vivo using optical coherence tomography (OCT). The specimens were prepared in blocks of 5 x 5 x 3 mm (width x length x height). The OCT imaging system was a swept source OCT system operating at wavelengths ranging between 1250 nm and 1360 nm with an average ...
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    6. Tissue characterization using optical coherence tomography and cone beam computed tomography: A comparative pilot study

      Tissue characterization using optical coherence tomography and cone beam computed tomography: A comparative pilot study
      Objectives To evaluate the ability of optical coherence tomography (OCT) in differentiating between human oral tissues in comparison with cone beam computed tomography (CBCT). Study design In this study, we imaged four types of tissues ex vivo , i.e., human enamel, human cortical bone, human trabecular bone, fatty tissue plus water and air using OCT (Axsun Inc. Billerica, MA). We then developed a method for qualitative and quantitative analysis of ...
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    7. Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue

      Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue
      In this manuscript, the initial feasibility of a catheter based phase stabilized swept source optical coherence tomography (OCT) system was studied for characterization of the strain inside different human ovarian tissue groups. The ovarian tissue samples were periodically compressed with 500 Hz square wave signal along the axial direction between the surface of an unfocused transducer and a glass cover slide. The displacement and corresponding strain were calculated during loading ...
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    8. Estimation of elastic parameters of ovarian tissue using phase stabilized swept source optical-coherence tomography

      Estimation of elastic parameters of ovarian tissue using phase stabilized swept source optical-coherence tomography
      We have estimated the micro-mechanical properties of ovarian tissue using phase-sensitive swept source optical coherence tomography. Ovary samples were mechanically excited by periodical vibration of an ultrasound transducer. The displacement and strain of the tissues were calculated during loading. Significant difference in strain was observed between the normal and malignant ovary groups, which indicates much softer and heterogeneous tissue structure for malignant ovaries. The initial results show that the phase ...
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    9. Physical Sciences Receives NIH Grant for Optical Coherence Tomography Based on Freeze Drying Microscopy

      Physical Sciences Receives NIH Grant for Optical Coherence Tomography Based on Freeze Drying Microscopy
      ...ds in 2015. Below is a summary of the proposed work. Physical Sciences Inc. (PSI), in collaboration with the University of Connecticut (UConn), proposes to develop the 2nd generation of an advanced 3D freeze-drying micr...
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    10. Optical and Photoacoustic Imaging for Ovarian Cancer Detection (Thesis)

      Optical and Photoacoustic Imaging for Ovarian Cancer Detection (Thesis)
      Ovarian cancer is the fifth most common cancer among women and has the highest mortality rate of all gynecologic cancers. Current clinical imaging modalities are limited by poor sensitivity and specificity. Therefore, there is an urgent need to develop effective tools to detect ovarian cancer. In this dissertation, two imaging modalities, optical coherence tomography (OCT) and photoacoustic imaging have been investigated for ovarian cancer detection and characterization. In the first ...
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    11. Physical Sciences Incorporated Receives NIH Grant for Optical Coherence Tomography Based Freeze Drying Microscopy

      Physical Sciences Incorporated Receives NIH Grant for Optical Coherence Tomography Based Freeze Drying Microscopy
      ...ds in 2015. A summary of the program is given below. Physical Sciences Inc. (PSI), in collaboration with the University of Connecticut (UConn), proposes to develop the 2nd generation of an advanced 3D freeze-drying micr...
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    12. Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy

      Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy
      The objective of this study was to assess the feasibility of developing and applying a laboratory tool that can provide three-dimensional product structural information during freeze-drying and which can accurately characterize the collapse temperature ( T c ) of pharmaceutical formulations designed for freeze-drying. A single-vial freeze dryer coupled with optical coherence tomography freeze-drying microscopy (OCTFDM) was developed to investigate the structure and T c of formulations in pharmaceutically relevant products containers ...
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    13. A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography

      A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography
      Wang, Tianheng; Yang, Yi; Zhu, QuingIn this paper, a logistic prediction model is introduced to characterize the ovarian tissue. A new parameter, the phase retardation rate, was extracted from phase images of polarization-sensitive optical coherence tomography (PS-OCT). Statistical significance of this parameter between normal and ... [Biomed. Opt. Express 4, 772-777 (2013)]
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    14. 1-15 of 41 1 2 3 »
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  2. About University of Connecticut

    University of Connecticut

    University of Connecticut was founded in 1881 as the Storrs Agricultural School and became the University of Connecticut in 1939. Additional information about the University's history and its traditions can be found on The UConn Story website. The University has ten schools and colleges at its main campus in Storrs, separate Schools of Law and Social Work in Hartford, five regional campuses throughout the state and Schools of Medicine and Dental Medicine at the UConn Health Center in Farmington. More information about our campuses can be found on the Campuses page.