1. University of Colorado

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    1. Mentioned In 39 Articles

    2. Association of Optical Coherence Tomography and Optical Coherence Tomography Angiography Retinal Features With Visual Function in Older Adults

      Association of Optical Coherence Tomography and Optical Coherence Tomography Angiography Retinal Features With Visual Function in Older Adults
      Importance Although there is abundant evidence relating neuronal and vascular optical coherence tomography (OCT) and OCT angiography (OCTA) measures to retinal disease, data on the normative distribution of retinal features and their associations with visual function in a healthy, older, community-based population are sparse. Objectives To characterize the normative OCT and OCTA measures in older adults and describe their associations with visual function. Design, Setting, and Participants This was a ...
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    3. NA-AION Risk Factors: New Perspectives

      NA-AION Risk Factors: New Perspectives
      Non-arteritic anterior ischemic optic neuropathy (NA-AION) is the most common acute optic neuropathy in the middle-aged and elderly population and can also occur in children and young adults. NA-AION leads to irreversible vision loss, and there is currently no effective treatment. In recent years, acellular calcified deposits in the optic nerve head called optic disc drusen (ODD) have been investigated as an important risk factor for NA-AION in patients under ...
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    4. OCT guided micro-focal ERG system with multiple stimulation wavelengths for characterization of ocular health

      OCT guided micro-focal ERG system with multiple stimulation wavelengths for characterization of ocular health
      Inherited retinal disorders and dry age-related macular degeneration are characterized by the degeneration and death of different types of photoreceptors at different rate and locations. Advancement of new therapeutic interventions such as optogenetics gene therapy and cell replacement therapies are dependent on electrophysiological measurements at cellular resolution. Here, we report the development of an optical coherence tomography (OCT) guided micro-focal multi-color laser stimulation and electroretinogram (ERG) platform for highly localized ...
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    5. Technical Feasibility on the Use of Optical Coherence Tomography in the Evaluation of Pediatric Pulmonary Venous Stenosis

      Technical Feasibility on the Use of Optical Coherence Tomography in the Evaluation of Pediatric Pulmonary Venous Stenosis
      Pulmonary vein stenosis (PVS) in children is a morbid disease and limited progress has been made in improving outcomes for this heterogenous group of patients. Evaluation is currently limited to imaging techniques that fail to provide an adequate overview of the intraluminal and luminal pathology perpetuating our limited understanding of this condition. Optical coherence tomography (OCT) is an imaging modality which provides intraluminal profiling with microstructural detail through optical reflective ...
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    6. Non-invasive monitoring of suprachoroidal, subretinal, and intravitreal implants using confocal scanning laser ophthalmoscope (cSLO) and optical coherence tomography (OCT)

      Non-invasive monitoring of suprachoroidal, subretinal, and intravitreal implants using confocal scanning laser ophthalmoscope (cSLO) and optical coherence tomography (OCT)
      To address the need for noninvasive monitoring of injectable preformed drug delivery implants in the eye, we developed noninvasive methods to monitor such implants from different locations within the eye. Cylindrical polymeric poly(lactide-co-glycolide) or metal implants were injected into isolated bovine eyes at suprachoroidal, subretinal, and intravitreal locations and imaged noninvasively using the cSLO and OCT modes of a Heidelberg Spectralis HRA+OCT instrument after adjusting for the corneal ...
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    7. Optical Coherence Tomography Angiography and Visual Field Progression in Primary Angle Closure Glaucoma

      Optical Coherence Tomography Angiography and Visual Field Progression in Primary Angle Closure Glaucoma
      Precis: Lower whole enface disc (coefficient: 0.02, P =0.03) and macular vessel densities (coefficient: 0.04, P =0.02) on OCT angiography were significantly associated with faster rate of mean deviation decline. Purpose: To evaluate the association between optical coherence tomography angiography (OCTA) features and prior visual field (VF) progression in primary angle closure glaucoma (PACG). Methods: In a cross-sectional study, 46 eyes of 31 PACG patients with ...
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    8. Spaceflight Associated Neuro-Ocular Syndrome (SANS): A Systematic Review and Future Directions

      Spaceflight Associated Neuro-Ocular Syndrome (SANS): A Systematic Review and Future Directions
      Purpose: To present a systematic review of the current body of literature surrounding spaceflight associated neuro-ocular syndrome (SANS) and highlight priorities for future research. Methods: Three major biomedical databases were searched with the following terms: ((neuro ocular) OR ((brain) AND (eye))) AND ((spaceflight) OR (astronaut) OR (microgravity)) AND (ENGLISH[Language]). Once duplicates were removed, 283 papers were left. Articles were excluded if they were not written in English or conference ...
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    9. Repeatability of binarization thresholding methods for optical coherence tomography angiography image quantification

      Repeatability of binarization thresholding methods for optical coherence tomography angiography image quantification
      Binarization is a critical step in analysis of retinal optical coherence tomography angiography (OCTA) images, but the repeatability of metrics produced from various binarization methods has not been fully assessed. This study set out to examine the repeatability of OCTA quantification metrics produced using different binarization thresholding methods, all of which have been applied in previous studies, across multiple devices and plexuses. Successive 33 mm foveal OCTA images of 13 ...
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    10. Toward image quality assessment in optical coherence tomography (OCT) of rat kidney

      Toward image quality assessment in optical coherence tomography (OCT) of rat kidney
      Background Optical coherence tomography (OCT) is a useful tool for the evaluation of structure and function of the kidney, but the image quality can be affected by many factors. Objective The objective of this study was to assess the image quality of different OCT systems in OCT imaging of the living kidney. Methods One swept-source OCT (SSOCT) of 1300nm, one spectral domain OCT (SDOCT) of 1300nm and another of 900nm ...
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    11. Iridocorneal Angle Assessment After Laser Iridotomy with Swept-source Optical Coherence Tomography

      Iridocorneal Angle Assessment After Laser Iridotomy with Swept-source Optical Coherence Tomography
      Aim: To investigate the reliability of anterior chamber angle (ACA) measurements in narrow angles and assess the effect of laser peripheral iridotomy (LPI) on these measurements using novel swept-source optical coherence tomography (SS-OCT) technology. Methods: In this prospective observational study, patients with gonioscopically narrow angles were enrolled and scheduled for prophylactic LPI. Twelve ACA sections were obtained in each eye using SS-OCT (ANTERION, Heidelberg Engineering, Germany) before and after Nd ...
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    12. Using the Pathophysiology of Dry AMD to Guide Binarization of the Choriocapillaris on OCTA: A Model

      Using the Pathophysiology of Dry AMD to Guide Binarization of the Choriocapillaris on OCTA: A Model
      Especially since the incorporation of swept laser sources, optical coherence tomography angiography (OCTA) has enabled quantification of choriocapillaris perfusion. A critical step in this process is binarization, which makes angiographic images quantifiable in terms of perfusion metrics. It remains challenging to have confidence that choriocapillaris perfusion metrics reflect the reality of pathophysiologic flow, largely because choice of binarization method can result in significantly different perfusion metric outcomes. This commentary discusses ...
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    13. Follow-Up of Nonarteritic Anterior Ischemic Optic Neuropathy With Optical Coherence Tomography Angiography

      Follow-Up of Nonarteritic Anterior Ischemic Optic Neuropathy With Optical Coherence Tomography Angiography
      Background: Peripapillary and macular microvasculature alterations after nonarteritic ischemic optic neuropathy (NAION) have been investigated in several studies. We aimed to explore the vascular changes from acute NAION (aNAION) to chronic NAION (cNAION). Methods: This prospective observational study composed of 16 eyes with aNAION and 40 healthy age-matched controls. Eyes with NAION were followed up for more than 6 months after acute event. Optical coherence tomography angiography (OCTA) was used ...
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    14. Accuracy of optical coherence tomography for diagnosing glaucoma: an overview of systematic reviews

      Accuracy of optical coherence tomography for diagnosing glaucoma: an overview of systematic reviews
      Aims To assess the diagnostic accuracy (DTA) of optical coherence tomography (OCT) for detecting glaucoma by systematically searching and appraising systematic reviews (SRs) on this issue. Methods We searched a database of SRs in eyes and vision maintained by the Cochrane Eyes and Vision United States on the DTA of OCT for detecting glaucoma. Two authors working independently screened the records, abstracted data and assessed the risk of bias using ...
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    15. Quantitative assessment of skin swelling using optical coherence tomography

      Quantitative assessment of skin swelling using optical coherence tomography
      Background Preclinical and clinical studies suggest that optical coherence tomography (OCT) is a useful tool to visualize inflammatory conditions. Objective The objective of this study was to evaluate the usefulness of combining OCT and various image processing techniques for quantitative assessment of histamine-induced tissue swelling. Methods Both time-domain and frequency-domain OCT were used on a mouse ear model. The ear thickness and volume before and after histamine challenge were determined ...
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    16. 1-15 of 39 1 2 3 »
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  2. About University of Colorado

    University of Colorado

    University of Colorado has been a leader in higher education and research in the Rocky Mountain region for 134 years. Founders laid the red-brick cornerstone of Old Main, the university's first building, in Boulder in 1876, the same year Colorado joined the union, and the nation marked its centennial. Since then, CU has evolved into a dynamic network of four campuses, including one of the newest biomedical and health care centers in the world. Today, the CU legacy for academic excellence, innovation and discovery continues at the University of Colorado at Boulder, the University of Colorado at Colorado Springs, the University of Colorado Denver and the University of Colorado Anschutz Medical Campus.