Articles that mention University of Cologne -Optical Coherence Tomography News

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2. Microscope-Integrated Optical Coherence Tomography-Guided Drainage of Acute Corneal Hydrops in Keratoconus Combined With Suturing and Gas-Aided Reattachment of Descemet Membrane
  
  Explore LWW Online Jul 8 2019 Ophthalmology
  
  Purpose: The treatment of acute corneal hydrops due to keratoconus has so far been limited to awaiting the spontaneous resorption of corneal edema, supportive care, and finally keratoplasty. A recent publication describes the surgical reattachment of Descemet Membrane (DM) facilitated by pre-Descemetic sutures and anterior chamber air/gas filling. Here, we present a novel microscope-integrated intraoperative optical coherence tomography ( MI-OCT )-guided technique for the immediate reattachment of DM in corneal ...
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  Mentions: University of Cologne
3. The Optimal Diameter for Circumpapillary Retinal Nerve Fiber Layer Thickness Measurement by SD-OCT in Glaucoma
  
  Explore LWW Online Jul 28 2018 Ophthalmology
  
  Purpose: To evaluate the diagnostic power for glaucoma detection using circumpapillary retinal nerve fiber layer (cRNFL) thickness in three diameter sizes from the center of the optic nerve head (ONH) by spectral domain optical coherence tomography (SD-OCT). Methods: In this cross-sectional study, case-control, 437 eyes diagnosed with glaucoma and 183 eyes of healthy controls underwent SD-OCT of the ONH, visual field testing, and a clinical examination. Circumpapillary RNFL thickness (cRNFL ...
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  Mentions: University of Cologne
4. Bruch’s membrane opening-based optical coherence tomography of the optic nerve head: a useful diagnostic tool to detect glaucoma in macrodiscs
  
  Explore Nature Publishing Group Jan 26 2018 Ophthalmology
  
  Purpose To compare Bruchs membrane opening (BMO)-based spectral domain optical coherence tomography (SD-OCT) and margin based confocal scanning laser tomography (CSLT) of the optic nerve head (ONH) to visual field function in large optic discs (macrodiscs) and to assess performance for glaucoma detection. Methods In a casecontrol, cross-sectional study, 125 eyes of 125 patients with disc size 2.45mm 2 , thereof 44 glaucoma and 11 ocular hypertension (OHT) patients ...
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  Mentions: University of Cologne
5. Label-Free In Vivo Imaging of Corneal Lymphatic Vessels Using Microscopic Optical Coherence Tomography
  
  Explore IOVS Journal Nov 19 2017
  
  Purpose : Corneal neovascularization, in particular lymphangiogenesis, is a limiting factor in corneal transplant survival. Novel treatment approaches focus on (selective) inhibition and regression of lymphatic vessels. Imaging clinically invisible corneal lymphatic vessels is a prerequisite for these strategies. Using a murine model, this study investigates whether corneal lymphatic vessels can be imaged using microscopic optical coherence tomography (mOCT). Methods : Corneal neovascularization was induced by intrastromal placement of 11.0 nylon ...
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  Mentions: University of Cologne Gereon Hüttmann University of Lübeck
6. Variability of choroidal and retinal thicknesses in healthy eyes using swept-source optical coherence tomography – implications for designing clinical trials
  
  Explore Medical Journals Publisher Oct 13 2017 Ophthalmology
  
  ...lbert Caramoy,1 Ludwig M Heindl2 1Eye Center Wolfsburg-Fallersleben, Wolfsburg, 2Department of Ophthalmology, University of Cologne, Cologne, Germany Aim: The aim was to study the variability of choroidal scleral interfa...
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7. Anterior Segment Optical Coherence Tomography for the Diagnosis of Corneal Dystrophies according to the IC3D Classification
  
  Explore Survey of Ophthalmology Aug 8 2017 Ophthalmology
  
  Corneal dystrophies are categorized according to the International Committee for Classification of Corneal Dystrophies (IC3D) classification, and their treatment depends on the affected structures and layer of the cornea. Therefore, estimating the depth and extent of the morphological changes due to the specific dystrophy is crucial when deciding between different treatment options. Besides superficial laser treatments and penetrating keratoplasty, minimal invasive lamellar keratoplasties such as Descemet membrane endothelial keratoplasty), deep ...
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  Mentions: University of Cologne
8. Robust total retina thickness segmentation in optical coherence tomography images using convolutional neural networks
  
  Explore OSA | OSA Publishing Jun 16 2017 Ophthalmology
  
  We developed a fully automated system using a convolutional neural network (CNN) for total retina segmentation in optical coherence tomography (OCT) that is robust to the presence of severe retinal pathology. A generalized U-net network architecture was introduced to include the large context needed to account for large retinal changes. The proposed algorithm outperformed qualitative and quantitatively two available algorithms. The algorithm accurately estimated macular thickness with an error of ...
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  Mentions: University of Cologne
9. Automated Staging of Age-Related Macular Degeneration Using Optical Coherence Tomography
  
  Explore IOVS Journal Apr 29 2017 Ophthalmology
  
  Purpose : To evaluate a machine learning algorithm that automatically grades age-related macular degeneration (AMD) severity stages from optical coherence tomography (OCT) scans. Methods : A total of 3265 OCT scans from 1016 patients with either no signs of AMD or with signs of early, intermediate, or advanced AMD were randomly selected from a large European multicenter database. A machine learning system was developed to automatically grade unseen OCT scans into different ...
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  Mentions: University of Cologne
10. Intraoperative Optical Coherence Tomography in Lamellar Keratoplasties: Indications and Outcomes
  
  Explore Home - Springer Oct 5 2016 Ophthalmology
  
  Purpose of Review Lamellar keratoplasties are evolving techniques to selectively replace diseased or opacified layers of the cornea. In recent years, the popularity of lamellar keratoplasties, especially Descemet membrane endothelial keratoplasty, Descemet stripping-automated endothelial keratoplasty and deep anterior lamellar keratoplasty, increased dramatically, since lamellar surgeries reduce intra- and postoperative complications and achieve faster visual recovery. Nonetheless, the surgical procedures are delicate. Recent Findings Novel imaging techniques, as intraoperative optical coherence ...
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  Mentions: University of Cologne
11. Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography
  
  Explore BJO Online Sep 22 2016 Ophthalmology
  
  Purpose To present in vivo anterior segment optical coherence tomography (OCT) features of infants with Peters' anomaly obtained during presurgical examination under general anaesthesia, and to evaluate the impact of OCT features on surgical decision making. Methods This is a single-centre, consecutive, observational case series including 44 eyes of 27 infants with Peters' anomaly (518 months) undergoing keratoplasty. Medical records of patients were reviewed retrospectively. Clinical features and OCT findings ...
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  Mentions: University of Cologne Fudan University Harvard University
12. The use of Bruch's membrane opening-based optical coherence tomography of the optic nerve head for glaucoma detection in microdiscs
  
  Explore BJO Online Jul 19 2016 Ophthalmology
  
  Purpose To assess the performance of Bruch's membrane opening (BMO)-based spectral domain optical coherence tomography (SD-OCT) of the optic nerve head for glaucoma detection in microdiscs in comparison with confocal scanning laser tomography (CSLT). Design Retrospective cohort study. Methods 82 eyes of 82 patients with disc size 1.63 mm 2 underwent SD-OCT and CSLT measurements, visual field testing and clinical examination. BMO-based minimal rim width (BMO-MRW), retinal ...
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  Mentions: University of Cologne University of Erlangen
13. Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis
  
  Explore Nature Publishing Group Jul 9 2016 Ophthalmology
  
  Purpose To analyze the macular structure in a large series of consecutive patients with different types of uveitis using spectral-domain optical coherence tomography (SD-OCT). Patients and methods Five hundred eyes of 500 consecutive patients with anterior, intermediate, posterior, and panuveitis underwent standardized macular examination using SD-OCT. Central retinal thickness (CRT), macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular edema (DME), serous retinal detachment (SRD), epiretinal membrane ...
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  Mentions: University of Cologne University of Erlangen
14. Neuroretinal rim in non-glaucomatous large optic nerve heads: a comparison of confocal scanning laser tomography and spectral domain optical coherence tomography
  
  Explore BJO Online Apr 26 2016 Ophthalmology
  
  Background/aims To compare margin-based rim area measurements from confocal scanning laser tomography (CSLT) with Bruch's membrane opening (BMO)-based measurements from spectral domain optical coherence tomography (SD-OCT) by analysis of a group of non-glaucomatous eyes with large optic discs, so-called macrodiscs (disc size 2.45 mm 2 in CSLT). Objective is to create a reference base for large optic nerve heads in SD-OCT diagnostics. Methods 102 eyes received ...
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  Mentions: University of Cologne
15. Intraoperative Optical Coherence Tomography Enables Noncontact Imaging During Canaloplasty
  
  Explore LWW Online Jan 15 2016 Ophthalmology
  
  Purpose: Here we describe intraoperative optical coherence tomography (iOCT) as a novel noncontact imaging tool for intraoperative monitoring and procedure evaluation during canaloplasty, as a nonpenetrating surgical technique to treat primary open angle glaucoma. Materials and Methods: Retrospective case report of a patient (63 y, female), who underwent traditional canaloplasty, using a commercially available 840 nm OCT device, mounted to an operating microscope (Rescan 700). Main outcome measures were the ...
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16. Intraoperative Optical Coherence Tomography Ocular Surgery on a Higher Level or Just Nice Pictures?
  
  Explore JAMA Network Aug 1 2015 Ophthalmology
  
  In recent years, optical coherence tomography (OCT) has developed into one of the most important imaging techniques in ophthalmology. Nonetheless, this technology is still evolving rapidly as recent developments in multimodal swept-source OCT devices and 4-dimensional real-time OCT demonstrate. Another currently developing sector in OCT application is the intraoperative use of OCT technology. Several approaches have been used to transfer OCT into an intraoperative setting, beginning with OCT-compatible positioning of ...
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  Mentions: University of Cologne
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