1. University of Cologne

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    1. Mentioned In 48 Articles

    2. ORCA study: real-world versus reading centre assessment of disease activity of neovascular age-related macular degeneration (nAMD)

      Explore BJO Online Ophthalmology
      ORCA study: real-world versus reading centre assessment of disease activity of neovascular age-related macular degeneration (nAMD)
      Background/aims The prospective, non-interventional ORCA module of the OCEAN study (Observation of Treatment Patterns with Lucentis in Approved Indications) evaluated the qualiy of spectral domain-optical coherence tomography (SD-OCT) image interpretation and treatment decisions by clinicians in Germany and the impact on visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD). Methods 2286 SD-OCT scans of 205 eyes were independently evaluated by clinicians and reading centres ...
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      Mentions: University of Cologne University of Tübingen Frank G. Holz

    3. Microscope-Integrated Optical Coherence Tomography-Guided Drainage of Acute Corneal Hydrops in Keratoconus Combined With Suturing and Gas-Aided Reattachment of Descemet Membrane

      Explore LWW Online Ophthalmology
      Microscope-Integrated Optical Coherence Tomography-Guided Drainage of Acute Corneal Hydrops in Keratoconus Combined With Suturing and Gas-Aided Reattachment of Descemet Membrane
      Purpose: The treatment of acute corneal hydrops due to keratoconus has so far been limited to awaiting the spontaneous resorption of corneal edema, supportive care, and finally keratoplasty. A recent publication describes the surgical reattachment of Descemet Membrane (DM) facilitated by pre-Descemetic sutures and anterior chamber air/gas filling. Here, we present a novel microscope-integrated intraoperative optical coherence tomography ( MI-OCT )-guided technique for the immediate reattachment of DM in corneal ...
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      Mentions: University of Cologne Haag-Streit

    4. The Optimal Diameter for Circumpapillary Retinal Nerve Fiber Layer Thickness Measurement by SD-OCT in Glaucoma

      Explore LWW Online Ophthalmology
      The Optimal Diameter for Circumpapillary Retinal Nerve Fiber Layer Thickness Measurement by SD-OCT in Glaucoma
      Purpose: To evaluate the diagnostic power for glaucoma detection using circumpapillary retinal nerve fiber layer (cRNFL) thickness in three diameter sizes from the center of the optic nerve head (ONH) by spectral domain optical coherence tomography (SD-OCT). Methods: In this cross-sectional study, case-control, 437 eyes diagnosed with glaucoma and 183 eyes of healthy controls underwent SD-OCT of the ONH, visual field testing, and a clinical examination. Circumpapillary RNFL thickness (cRNFL ...
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      Mentions: University of Cologne

    5. Bruch’s membrane opening-based optical coherence tomography of the optic nerve head: a useful diagnostic tool to detect glaucoma in macrodiscs

      Explore Nature Publishing Group Ophthalmology
      Bruch’s membrane opening-based optical coherence tomography of the optic nerve head: a useful diagnostic tool to detect glaucoma in macrodiscs
      Purpose To compare Bruchs membrane opening (BMO)-based spectral domain optical coherence tomography (SD-OCT) and margin based confocal scanning laser tomography (CSLT) of the optic nerve head (ONH) to visual field function in large optic discs (macrodiscs) and to assess performance for glaucoma detection. Methods In a casecontrol, cross-sectional study, 125 eyes of 125 patients with disc size 2.45mm 2 , thereof 44 glaucoma and 11 ocular hypertension (OHT) patients ...
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      Mentions: University of Cologne

    6. Label-Free In Vivo Imaging of Corneal Lymphatic Vessels Using Microscopic Optical Coherence Tomography

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      Label-Free In Vivo Imaging of Corneal Lymphatic Vessels Using Microscopic Optical Coherence Tomography
      Purpose : Corneal neovascularization, in particular lymphangiogenesis, is a limiting factor in corneal transplant survival. Novel treatment approaches focus on (selective) inhibition and regression of lymphatic vessels. Imaging clinically invisible corneal lymphatic vessels is a prerequisite for these strategies. Using a murine model, this study investigates whether corneal lymphatic vessels can be imaged using microscopic optical coherence tomography (mOCT). Methods : Corneal neovascularization was induced by intrastromal placement of 11.0 nylon ...
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      Mentions: University of Cologne Gereon Hüttmann University of Lübeck

    7. Variability of choroidal and retinal thicknesses in healthy eyes using swept-source optical coherence tomography – implications for designing clinical trials

      Explore Medical Journals Publisher Ophthalmology
      Variability of choroidal and retinal thicknesses in healthy eyes using swept-source optical coherence tomography – implications for designing clinical trials
      ...lbert Caramoy,1 Ludwig M Heindl2 1Eye Center Wolfsburg-Fallersleben, Wolfsburg, 2Department of Ophthalmology, University of Cologne, Cologne, Germany Aim: The aim was to study the variability of choroidal scleral interfa...
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      Mentions: University of Cologne

    8. Anterior Segment Optical Coherence Tomography for the Diagnosis of Corneal Dystrophies according to the IC3D Classification

      Explore Survey of Ophthalmology Ophthalmology
      Anterior Segment Optical Coherence Tomography for the Diagnosis of Corneal Dystrophies according to the IC3D Classification
      Corneal dystrophies are categorized according to the International Committee for Classification of Corneal Dystrophies (IC3D) classification, and their treatment depends on the affected structures and layer of the cornea. Therefore, estimating the depth and extent of the morphological changes due to the specific dystrophy is crucial when deciding between different treatment options. Besides superficial laser treatments and penetrating keratoplasty, minimal invasive lamellar keratoplasties such as Descemet membrane endothelial keratoplasty), deep ...
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      Mentions: University of Cologne

    9. Robust total retina thickness segmentation in optical coherence tomography images using convolutional neural networks

      Explore OSA | OSA Publishing Ophthalmology
      Robust total retina thickness segmentation in optical coherence tomography images using convolutional neural networks
      We developed a fully automated system using a convolutional neural network (CNN) for total retina segmentation in optical coherence tomography (OCT) that is robust to the presence of severe retinal pathology. A generalized U-net network architecture was introduced to include the large context needed to account for large retinal changes. The proposed algorithm outperformed qualitative and quantitatively two available algorithms. The algorithm accurately estimated macular thickness with an error of ...
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      Mentions: University of Cologne

    10. Automated Staging of Age-Related Macular Degeneration Using Optical Coherence Tomography

      Explore IOVS Journal Ophthalmology
      Automated Staging of Age-Related Macular Degeneration Using Optical Coherence Tomography
      Purpose : To evaluate a machine learning algorithm that automatically grades age-related macular degeneration (AMD) severity stages from optical coherence tomography (OCT) scans. Methods : A total of 3265 OCT scans from 1016 patients with either no signs of AMD or with signs of early, intermediate, or advanced AMD were randomly selected from a large European multicenter database. A machine learning system was developed to automatically grade unseen OCT scans into different ...
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      Mentions: University of Cologne

    11. Intraoperative Optical Coherence Tomography in Lamellar Keratoplasties: Indications and Outcomes

      Explore Home - Springer Ophthalmology
      Intraoperative Optical Coherence Tomography in Lamellar Keratoplasties: Indications and Outcomes
      Purpose of Review Lamellar keratoplasties are evolving techniques to selectively replace diseased or opacified layers of the cornea. In recent years, the popularity of lamellar keratoplasties, especially Descemet membrane endothelial keratoplasty, Descemet stripping-automated endothelial keratoplasty and deep anterior lamellar keratoplasty, increased dramatically, since lamellar surgeries reduce intra- and postoperative complications and achieve faster visual recovery. Nonetheless, the surgical procedures are delicate. Recent Findings Novel imaging techniques, as intraoperative optical coherence ...
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      Mentions: University of Cologne

    12. Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography

      Explore BJO Online Ophthalmology
      Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography
      Purpose To present in vivo anterior segment optical coherence tomography (OCT) features of infants with Peters' anomaly obtained during presurgical examination under general anaesthesia, and to evaluate the impact of OCT features on surgical decision making. Methods This is a single-centre, consecutive, observational case series including 44 eyes of 27 infants with Peters' anomaly (518 months) undergoing keratoplasty. Medical records of patients were reviewed retrospectively. Clinical features and OCT findings ...
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      Mentions: University of Cologne Fudan University Harvard University

    13. The use of Bruch's membrane opening-based optical coherence tomography of the optic nerve head for glaucoma detection in microdiscs

      Explore BJO Online Ophthalmology
      The use of Bruch's membrane opening-based optical coherence tomography of the optic nerve head for glaucoma detection in microdiscs
      Purpose To assess the performance of Bruch's membrane opening (BMO)-based spectral domain optical coherence tomography (SD-OCT) of the optic nerve head for glaucoma detection in microdiscs in comparison with confocal scanning laser tomography (CSLT). Design Retrospective cohort study. Methods 82 eyes of 82 patients with disc size 1.63 mm 2 underwent SD-OCT and CSLT measurements, visual field testing and clinical examination. BMO-based minimal rim width (BMO-MRW), retinal ...
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      Mentions: University of Cologne University of Erlangen

    14. Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis

      Explore Nature Publishing Group Ophthalmology
      Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis
      Purpose To analyze the macular structure in a large series of consecutive patients with different types of uveitis using spectral-domain optical coherence tomography (SD-OCT). Patients and methods Five hundred eyes of 500 consecutive patients with anterior, intermediate, posterior, and panuveitis underwent standardized macular examination using SD-OCT. Central retinal thickness (CRT), macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular edema (DME), serous retinal detachment (SRD), epiretinal membrane ...
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      Mentions: University of Cologne University of Erlangen

    15. Neuroretinal rim in non-glaucomatous large optic nerve heads: a comparison of confocal scanning laser tomography and spectral domain optical coherence tomography

      Explore BJO Online Ophthalmology
      Neuroretinal rim in non-glaucomatous large optic nerve heads: a comparison of confocal scanning laser tomography and spectral domain optical coherence tomography
      Background/aims To compare margin-based rim area measurements from confocal scanning laser tomography (CSLT) with Bruch's membrane opening (BMO)-based measurements from spectral domain optical coherence tomography (SD-OCT) by analysis of a group of non-glaucomatous eyes with large optic discs, so-called macrodiscs (disc size 2.45 mm 2 in CSLT). Objective is to create a reference base for large optic nerve heads in SD-OCT diagnostics. Methods 102 eyes received ...
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      Mentions: University of Cologne

    16. Intraoperative Optical Coherence Tomography Enables Noncontact Imaging During Canaloplasty

      Explore LWW Online Ophthalmology
      Intraoperative Optical Coherence Tomography Enables Noncontact Imaging During Canaloplasty
      Purpose: Here we describe intraoperative optical coherence tomography (iOCT) as a novel noncontact imaging tool for intraoperative monitoring and procedure evaluation during canaloplasty, as a nonpenetrating surgical technique to treat primary open angle glaucoma. Materials and Methods: Retrospective case report of a patient (63 y, female), who underwent traditional canaloplasty, using a commercially available 840 nm OCT device, mounted to an operating microscope (Rescan 700). Main outcome measures were the ...
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      Mentions: University of Cologne
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  4. About University of Cologne

    University of Cologne

    University of Cologne is one of the oldest universities in Europe and, with over 44,000 students, one of the largest universities in Germany. The university is part of the Deutsche Forschungsgemeinschaft, a society of Germany's leading research universities. Furthermore, it is the German representative and founding member in the Community of European Management Schools (CEMS).

    The University of Cologne is committed to research and development. The many projects being promoted by the German Research Foundation and the European Union at the university of Cologne, underline its reputation on an international level.

     
    Additionally, over 250 institutions, which cooperate with the university of Cologne, guarantee the support of teaching and research. The research strategy of the university therefore enforces and develops the work of interdisciplinary research centres and supports collaboration with international academic and industrial partners.
     
    As a result, interdisciplinary fields of study are constantly being developed. Students who expect demanding

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