1. University of Cambridge

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    1. Mentioned In 32 Articles

    2. In vivo light fluence correction for determination of tissue absorption coefficient using multispectral optoacoustic tomography

      In vivo light fluence correction for determination of tissue absorption coefficient using multispectral optoacoustic tomography
      Optoacoustic Tomography is a fast developing imaging modality, combining the high resolution and penetration depth of ultrasound detection with the high contrast available from optical absorption in tissue. The spectral profile of near infrared excitation light used in optoacoustic tomography instruments is modified by absorption and scattering as it propagates deep into biological tissue. The resulting images therefore provide only qualitative insight into the distribution of tissue chromophores. Knowledge of ...
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    3. Direct Comparison of Virtual-Histology Intravascular Ultrasound and Optical Coherence Tomography Imaging for Identification of Thin-Cap Fibroatheroma

      Direct Comparison of Virtual-Histology Intravascular Ultrasound and Optical Coherence Tomography Imaging for Identification of Thin-Cap Fibroatheroma
      Background Although rupture of thin-cap fibroatheroma (TCFA) underlies most myocardial infarctions, reliable TCFA identification remains challenging. Virtual-histology intravascular ultrasound (VH-IVUS) and optical coherence tomography (OCT) can assess tissue composition and classify plaques. However, direct comparisons between VH-IVUS and OCT are lacking and it remains unknown whether combining these modalities improves TCFA identification. Methods and Results Two hundred fifty-eight regions-of-interest were obtained from autopsied human hearts, with plaque composition and classification ...
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    4. Optical coherence tomography imaging of coronary atherosclerosis is affected by intraobserver and interobserver variability

      Optical coherence tomography imaging of coronary atherosclerosis is affected by intraobserver and interobserver variability
      Aims: Optical coherence tomography (OCT) has emerged as a novel imaging modality that allows plaque classification through identification of features including lipid, calcification and fibrous cap. However, subtle changes in light attenuation as the optical beam traverses the plaque in vivo are challenging to interpret and data on strength of observer agreement are minimal. Thus, we sought to assess both the intra and interobserver variability for plaque composition/classification using ...
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    5. Comparison of Corneal Epithelial Thickness Measurement Between Fourier-Domain OCT and Very High-Frequency Digital Ultrasound

      Comparison of Corneal Epithelial Thickness Measurement Between Fourier-Domain OCT and Very High-Frequency Digital Ultrasound
      To compare measurements of corneal epithelial thickness using optical coherence tomography (OCT) and very high-frequency digital ultrasound (VHFDU). METHODS: Retrospective analysis of 189 virgin corneas and 175 post-laser refractive surgery (LRS) corneas that had corneal epithelial thickness measurement with RTVue Fourier-domain OCT (Optovue, Inc., Fremont, CA) (tear film included) and Artemis VHFDU (ArcScan Inc., Morrison, CO) (tear film excluded). Averages were calculated for the central 2-mm diameter zone and for ...
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    6. Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis

      Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis
      Invasive imaging modalities, in particular intravascular ultrasound (IVUS) and optical coherence tomography (OCT), have become established tools for the in vivo study of coronary atherosclerosis. Their use in clinical studies has confirmed histopathological observations that certain important plaque features, such as thin fibrous caps and large lipid cores, are associated with plaque rupture, the precipitating event for the majority of myocardial infarctions. Serial imaging studies have also successfully been used ...
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    7. Cholesterol crystals identified using optical coherence tomography and virtual histology intravascular ultrasound

      Cholesterol crystals identified using optical coherence tomography and virtual histology intravascular ultrasound
      The deposition and accumulation of lipid within the arterial wall leads to the development and progression of atherosclerotic plaques. Cholesterol crystals (CCs) are formed from these lipid pools and both augment the inflammatory response and promote plaque rupture, possibly through inducing mechanical instability. Accordingly, identification of these structures is important for plaque risk stratification. Optical coherence tomography (OCT) and virtual histology intravascular ultrasound (VH-IVUS) are invasive imaging modalities that permit ...
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    8. Quantifying pharmaceutical film coating with optical coherence tomography and terahertz pulsed imaging: an evaluation

      Quantifying pharmaceutical film coating with optical coherence tomography and terahertz pulsed imaging: an evaluation
      Spectral domain optical coherence tomography (SD-OCT) has recently attracted a lot of interest in the pharmaceutical industry as a fast and non-destructive modality for quantification of thin film coatings that cannot easily be resolved with other techniques. Due to the relative infancy of this technique, much of the research to date has focused on developing the in-line measurement technique for assessing film coating thickness. To better assess OCT for pharmaceutical ...
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    9. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus

      British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus
      These guidelines provide a practical and evidence-based resource for the management of patients with Barrett's oesophagus and related early neoplasia. The Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument was followed to provide a methodological strategy for the guideline development. A systematic review of the literature was performed for English language articles published up until December 2012 in order to address controversial issues in Barrett's oesophagus ...
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    10. Comparison of Residual Stromal Bed Thickness Measurement Among Very High-frequency Digital Ultrasound, Intraoperative Handheld Ultrasound, and Optical Coherence Tomography

      Comparison of Residual Stromal Bed Thickness Measurement Among Very High-frequency Digital Ultrasound, Intraoperative Handheld Ultrasound, and Optical Coherence Tomography
      ... the materials presented herein. Preparation in part fulfillment of the requirements for the doctoral thesis, University of Cambridge, for Dr Reinstein. AUTHOR CONTRIBUTIONS Study concept and design (D.Z.R., T.J.A., M.G....
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    11. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      ...of Sheffield $4,788,890 Cranfield University $3,051,140 University of Kent $2,340,477 University of Cambridge $1,417,014 The Nottingham Trent University $1,084,727 Keele University...
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  2. About University of Cambridge

    University of Cambridge

    University of Cambridge (informally Cambridge University or Cambridge) is a public research university located in Cambridge, United Kingdom. It is the second-oldest university in the English-speaking world (after the University of Oxford), and the seventh-oldest globally. In post-nominals the university's name is abbreviated as Cantab, a shortened form of Cantabrigiensis (an adjective derived from Cantabrigia, the Latinised form of Cambridge).