1. University of British Columbia

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    1. Mentioned In 78 Articles

    2. Enhanced depth imaging in swept-source optical coherence tomography: Improving visibility of choroid and sclera, a masked study

      Enhanced depth imaging in swept-source optical coherence tomography: Improving visibility of choroid and sclera, a masked study
      Purpose To compare enhanced depth imaging in swept-source optical coherence tomography and nonenhanced depth imaging optical coherence tomography in their ability to capture choroidal and scleral details. Methods Averaged foveal B-Scans were obtained from 40 eyes of 20 healthy volunteers by swept-source optical coherence tomography with and without enhanced depth imaging. Visibility and contrast of vascular details within the choroid, choroidoscleral junction, and sclera were evaluated by masked readers using ...
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    3. Application of optical coherence tomography angiography in diabetic retinopathy: a comprehensive review

      Application of optical coherence tomography angiography in diabetic retinopathy: a comprehensive review
      Optical coherence tomography angiography (OCTA) is a noninvasive method that enables visualization of blood flow within retinal vessels down to the size of capillaries by detecting motion contrast from moving blood cells. OCTA provides a fast and safe procedure to assess retinal microvasculature with higher contrast and resolution than conventional fluorescence angiography . The different capillary plexuses are displayed separately and their perfusion density can be quantified. Imaging capabilities such as ...
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    4. Slope-based segmentation of articular cartilage using polarization-sensitive optical coherence tomography phase retardation image

      Slope-based segmentation of articular cartilage using polarization-sensitive optical coherence tomography phase retardation image
      A segmentation method based on phase retardation measurements from polarization-sensitive optical coherence tomography (PS-OCT) is developed to differentiate the structural zones of articular cartilage. The organization of collagen matrix in articular cartilage varies over the different structural zones, generating different tissue birefringence. Analyzing the slope of the accumulated phase retardation at different depths can detect the variation in tissue birefringence and be used to segment the structural zones. The method ...
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    5. Deep-Learning based Multiclass Retinal Fluid Segmentation and Detection in Optical Coherence Tomography Images using a Fully Convolutional Neural Network

      Deep-Learning based Multiclass Retinal Fluid Segmentation and Detection in Optical Coherence Tomography Images using a Fully Convolutional Neural Network
      As a non-invasive imaging modality, optical coherence tomography (OCT) can provide micrometer-resolution 3D images of retinal structures. These images can help reveal disease-related alterations below the surface of the retina, such as the presence of edema, or accumulation of fluid which can distort vision, and are an indication of disruptions in the vasculature of the retina. In this paper, a new framework is proposed for multiclass fluid segmentation and detection ...
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    6. Colloidal silver toxicity with absence of choroidal signal on optical coherence tomography

      Colloidal silver toxicity with absence of choroidal signal on optical coherence tomography
      Silver, aside from its physical properties making it popular for electric applications and in jewellery, has a history of being used to treat various medical conditions. 1 It has been used to treat mental illness, epilepsy, gastrointestinal disorders, and infectious diseases and in surgical prostheses. 1 A review performed by Drake and Hazelwood in 2005 suggested that metallic silver posed minimal risk to healththe most common side effects being argyria ...
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    7. EN FACE OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF INNER RETINAL DIMPLES AFTER INTERNAL LIMITING MEMBRANE PEELING FOR FULL-THICKNESS MACULAR HOLES

      EN FACE OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF INNER RETINAL DIMPLES AFTER INTERNAL LIMITING MEMBRANE PEELING FOR FULL-THICKNESS MACULAR HOLES
      Purpose: To quantitatively and qualitatively evaluate the microvascular and structural abnormalities associated with inner retinal dimpling after internal limiting membrane peeling for full-thickness macular holes using sequential en face optical coherence tomography ( OCT ) and OCT angiography. Methods: Thirteen eyes of 13 patients with idiopathic full-thickness macular holes were enrolled in the study. Patients were treated with pars plana vitrectomy , internal limiting membrane peeling, and gas tamponade. Subjects were evaluated preoperatively ...
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    8. Macular Involvement in Diabetic Retinopathy Evaluated With Swept-Source OCT

      Macular Involvement in Diabetic Retinopathy Evaluated With Swept-Source OCT
      The prevalence of diabetes mellitus (DM) is increasing worldwide. Diabetic retinopathy is the most prevalent complication of DM and a leading cause of visual impairment due to closure of capillaries. High-resolution imaging techniques of the retina and its supplying vascular networks can allow novel insight to subtle changes that cannot be appreciated in standard fundus examination. In this study capillary changes of patients with different severity levels of diabetic retinopathy ...
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    9. Automated identification of cone photoreceptors in adaptive optics optical coherence tomography images using transfer learning

      Automated identification of cone photoreceptors in adaptive optics optical coherence tomography images using transfer learning
      Automated measurements of the human cone mosaic requires the identification of individual cone photoreceptors. The current gold standard, manual labeling, is a tedious process and can not be done in a clinically useful timeframe. As such, we present an automated algorithm for identifying cone photoreceptors in adaptive optics optical coherence tomography (AO-OCT) images. Our approach fine-tunes a pre-trained convolutional neural network originally trained on AO scanning laser ophthalmoscope (AO-SLO) images ...
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    10. Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography

      Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography
      Computational models and experimental optical mapping of cardiac electrophysiology serve as powerful tools to investigate the underlying mechanisms of arrhythmias . Modeling can also aid the interpretation of optical mapping signals, which may have different characteristics with respect to the underlying electrophysiological signals they represent. However, despite the prevalence of atrial arrhythmias such as atrial fibrillation , models of optical electrical mapping incorporating realistic structure of the atria are lacking. Therefore, we ...
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    11. Strip-based registration of serially acquired optical coherence tomography angiography

      Strip-based registration of serially acquired optical coherence tomography angiography
      The visibility of retinal microvasculature in optical coherence tomography angiography (OCT-A) images is negatively affected by the small dimension of the capillaries, pulsatile blood flow, and motion artifacts. Serial acquisition and time-averaging of multiple OCT-A images can enhance the definition of the capillaries and result in repeatable and consistent visualization. We demonstrate an automated method for registration and averaging of serially acquired OCT-A images. Ten OCT-A volumes from six normal ...
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    12. Anterior Segment Optical Coherence Tomography for Targeted Transconjunctival Suture Placement in Overfiltering Trabeculectomy Blebs

      Anterior Segment Optical Coherence Tomography for Targeted Transconjunctival Suture Placement in Overfiltering Trabeculectomy Blebs
      Purpose: To demonstrate the utility of swept-source anterior segment optical coherence tomography (SS-AS-OCT) in guiding placement of transconjunctival sutures in hypotonous patients after a trabeculectomy. Patients and Methods: This is a longitudinal case series of 10 eyes from 10 patients who required transconjunctival sutures after a trabeculectomy. SS-AS-OCT was used to aid in the placement of the sutures to improve the function of the overfiltering bleb. Results: SS-AS-OCT reliably identified ...
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    13. Correlation between polarization sensitive optical coherence tomography and SHG microscopy in articular cartilage

      Correlation between polarization sensitive optical coherence tomography and SHG microscopy in articular cartilage
      Polarization-sensitive optical coherence tomography (PS-OCT) and second harmonic generation (SHG) microscopy are two imaging modalities with different resolutions, field-of-views (FOV), and contrasts, while they both have the capability of imaging collagen fibers in biological tissues. PS-OCT can measure the tissue birefringence which is induced by highly organized fibers while SHG can image the collagen fiber organization with high resolution. Articular cartilage, with abundant structural collagen fibers, is a suitable sample ...
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    14. Spectral domain optical coherence tomography-guided versus 1-week facedown-posturing after macular hole surgery

      Spectral domain optical coherence tomography-guided versus 1-week facedown-posturing after macular hole surgery
      Objective To compare idiopathic full-thickness macular hole (FTMH) closure rates and postoperative best-corrected visual acuity (BCVA) between spectral domain optical coherence tomography (SD-OCT)guided facedown posturing and conventional 1-week facedown posturing after macular hole surgery. Design A retrospective comparative study. Participants Thirty-one consecutive eyes that underwent surgery for FTMH between July 2013 and September 2014 were divided into 2 groups. Methods In the SD-OCT-guided group, SD-OCT was performed on the ...
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  2. About University of British Columbia

    University of British Columbia

    University of British Columbia, UBC, is a Canadian public research university with campuses in Vancouver and Kelowna. UBC is rated as one of Canada’s top universities, and is usually considered one of the top 50 universities in the world.