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    1. Mentioned In 84 Articles

    2. ASSESSMENT OF EARLY CHANGES IN SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY AFTER INITIATION OF TREATMENT WITH INTRAVITREAL AFLIBERCEPT (EYLEA) OVER A 12-WEEK PERIOD FOR PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION:A Multicenter French Study

      Explore LWW Online Ophthalmology
      ASSESSMENT OF EARLY CHANGES IN SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY AFTER INITIATION OF TREATMENT WITH INTRAVITREAL AFLIBERCEPT (EYLEA) OVER A 12-WEEK PERIOD FOR PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION:A Multicenter French Study
      Purpose: To assess early changes in spectral-domain optical coherence tomography during the loading phase with intravitreal aflibercept therapy in patients with neovascular age-related macular degeneration. Methods: In this prospective, open-label, single-arm, multicenter study, patients with neovascular age-related macular degeneration, who were antivascular endothelial growth factor treatment-nave, received three monthly initial doses of intravitreal aflibercept 2 mg. The primary outcome was the proportion of patients with dry spectral-domain optical coherence tomography ...
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      Mentions: University of Bern Centre Hospitalier Intercommunal de Créteil

    3. AUTOMATED RETINAL LAYER SEGMENTATION AND THEIR THICKNESS PROFILES IN HEALTHY SUBJECTS: A Comparison of 55° Wide-field and Conventional 30° Spectral Domain-Optical Coherence Tomography

      Explore LWW Online Ophthalmology
      AUTOMATED RETINAL LAYER SEGMENTATION AND THEIR THICKNESS PROFILES IN HEALTHY SUBJECTS: A Comparison of 55° Wide-field and Conventional 30° Spectral Domain-Optical Coherence Tomography
      Purpose: To assess whether retinal thickness measurements with a standard 30 spectral domain optical coherence tomography (SD- OCT ) are comparable with wide-field 55 SD- OCT . Methods: Thirty-three healthy individuals were scanned using 55 as well as 30 SD- OCT according to a standardized protocol. Automated retinal layer segmentation of standard and wide-field SD-OCTs was assessed using customized software. Results: Both lenses showed a high correlation when analyzing total retinal thickness ...
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      Mentions: Heidelberg Engineering University of Bern Bern University Hospital

    4. Comparison of Drusen Volume Assessed by Two Different OCT Devices

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      Comparison of Drusen Volume Assessed by Two Different OCT Devices
      To compare drusen volume between Heidelberg Spectral Domain (SD-) and Zeiss Swept-Source (SS) PlexElite Optical Coherence Tomography (OCT) determined by manual and automated segmentation methods. Thirty-two eyes of 24 patients with Age-Related Macular Degeneration (AMD) and drusen maculopathy were included. In the central 1 and 3 mm ETDRS circle drusen volumes were calculated and compared. Drusen segmentation was performed using automated manufacturer algorithms of the two OCT devices. Then, the ...
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      Mentions: University of Bern Bern University Hospital

    5. Peri-procedural stent thrombosis following bifurcational PCI of lipid-rich plaque: serial optical coherence tomography insights

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      Peri-procedural stent thrombosis following bifurcational PCI of lipid-rich plaque: serial optical coherence tomography insights
      Pre-procedural optical coherence tomography (OCT) of the left anterior descending artery (LAD) in a 58-year-old man with unstable angina due to a stenosis involving LAD and first diagonal branch detected underlying mixed plaque, partially containing lipid in a circumferential distribution distal to the first diagonal branch (Figures A1-3). Bifurcational percutaneous coronary intervention with side-branch-stenting (double-kissing mini-crush: 2.0x18mm zotarolimus-eluting-stent (ZES) in diagonal branch, 2.25x38mm-ZES in LAD with post-dilation using ...
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      Mentions: University of Bern Bern University Hospital

    6. Vasculature of a minipig eye (microCT Group, Institute of Anatomy, University of Bern)

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      Vasculature of a minipig eye (microCT Group, Institute of Anatomy, University of Bern)
      MicroangioCT of a minipig eye (collaboration with Vetsuisse Faculty, University of Zurich and OCTlab Research Laboratory, Department of Ophthalmology, University of Basel). Contrast agent used: Angiofil (Fumedica AG, Switzerland). Scanner: desktop microCT-scanner Skyscan 1172 (Bruker microCT, Belgium). Isotrpic voxel size: 6.56m.
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      Mentions: University of Zurich University of Bern

    7. Conjunctival Microangiopathy in Diabetes Mellitus Assessed with Optical Coherence Tomography Angiography

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      Conjunctival Microangiopathy in Diabetes Mellitus Assessed with Optical Coherence Tomography Angiography
      Purpose : To detect and quantify conjunctival microangiopathy with optical coherence tomography angiography (OCTA). Methods : Imaging was performed in the temporal and nasal quadrant of the conjunctiva using a Heidelberg Spectralis spectral domain-OCT in OCTA mode adding a 25D lens to the standard 30 fundus lens. Images were acquired within a 10 5 cube at the limbus. Binary images were analyzed using ImageJ (Fiji software version 2.0) and an average ...
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      Mentions: University of Bern Bern University Hospital

    8. Utility of Multimodality Intravascular Imaging and the Local Hemodynamic Forces to Predict Atherosclerotic Disease Progression

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      Utility of Multimodality Intravascular Imaging and the Local Hemodynamic Forces to Predict Atherosclerotic Disease Progression
      Objectives This study sought to examine the utility of multimodality intravascular imaging and of the endothelial shear stress (ESS) distribution to predict atherosclerotic evolution. Background There is robust evidence that intravascular ultrasound (IVUS)-derived plaque characteristics and ESS distribution can predict, with however limited accuracy, atherosclerotic evolution; nevertheless, it is yet unclear whether multimodality imaging and ESS mapping enable more accurate prediction of coronary plaque progression. Methods A total of ...
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      Mentions: Imperial College London University College London University of Copenhagen

    9. Randomized comparison of optical coherence tomography versus angiography to guide Bioresorbable vascular scaffold implantation: The OPTICO BVS stud

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      Randomized comparison of optical coherence tomography versus angiography to guide Bioresorbable vascular scaffold implantation: The OPTICO BVS stud
      Purpose We investigated whether optical coherence tomography (OCT)-guided bioresorbable vascular scaffolds (BVS) implantation can improve in-scaffold minimal lumen area (MLA) at 6-month compared with angiography guidance. Methods The OPTICO BVS was a randomized, international multicenter, assessor blind, superiority trial comparing OCT- versus angiography-guided percutaneous coronary intervention (PCI) (1:1 allocation) in patients with coronary artery disease undergoing Absorb BVS 1.1 implantation. The primary endpoint was in-scaffold MLA at ...
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      Mentions: University of Bern Bern University Hospital Kings College London

    10. Optical Coherence Tomography Analysis of Cystoid Macular Edema in Retinal Dystrophy Treated with Oral Acetazolamide: Two Cases

      Explore thieme-connect.de Ophthalmology
      Optical Coherence Tomography Analysis of Cystoid Macular Edema in Retinal Dystrophy Treated with Oral Acetazolamide: Two Cases
      Enhanced S-cone syndrome (ESCS) is an autosomal recessive retinal dystrophy associated with a NR2E3 mutation, causing night blindness, decreased visual acuity, and visual field defects [ 1 ]. Clinically, ESCS is characterized by annular pigmentation along the vascular arcades and macular abnormalities [ 2 ]. Best vitelliform macular dystrophy (BVMD) is also an autosomal but dominant hereditary retinal dystrophy associated with the BEST1 gene, which affects central vision with a relatively good prognosis and ...
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      Mentions: University of Bern

    11. Differences in the presentation of stage 1 macular holes illustration by optical coherence tomography

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      Differences in the presentation of stage 1 macular holes illustration by optical coherence tomography
      Objective: To present two different phases of progression of Gass stage 1 foveolar detachment to lamellar or full-thickness macular holes revealed with spectral domain optical coherence tomography. Design: This is an observational study. Participants: The medical records of four patients (four eyes) with foveolar detachment that had evolved into stage 1 macular holes were compared. The patients manifested neither co-existing myopia nor any other ocular pathology. Methods: At each consultation ...
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      Mentions: University of Bern Università Vita-Salute San Raffaele

    12. In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study

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      In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study
      Aims We assessed morphological features of near-infrared spectroscopy (NIRS)-detected lipid-rich plaques (LRPs) by using optical coherence tomography (OCT) and intravascular ultrasound (IVUS). Methods and results IVUS-NIRS and OCT were performed in the two non-infarct-related arteries (non-IRAs) in patients undergoing percutaneous coronary intervention for treatment of an acute coronary syndrome. A lesion was defined as the 4mm segment with the maximum amount of lipid core burden index (maxLCBI 4mm ) of ...
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      Mentions: Medical University of Vienna University of Bern Bern University Hospital

    13. Efficacy and Reproducibility of Attenuation-Compensated Optical Coherence Tomography for Assessing External Elastic Membrane Border and Plaque Composition in Native and Stented Segments ― An In Vivo and Histology-Based Study ―

      Explore jstage.jst.go.jp Cardiology
      Efficacy and Reproducibility of Attenuation-Compensated Optical Coherence Tomography for Assessing External Elastic Membrane Border and Plaque Composition in Native and Stented Segments ― An In Vivo and Histology-Based Study ―
      Background: Attenuation-compensated (AC) technique was recently introduced to improve the plaque characterization of optical coherence tomography (OCT). Histological validation demonstrated promising results but the efficacy and reproducibility of this technique for assessing in-vivo tissue composition remains unclear. Methods and Results: OCT images portraying native (n=200) and stented (n=200) segments and 31 histological cross-sections were analyzed. AC-OCT appeared superior to conventional (C)-OCT in detecting the external elastic lamina ...
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      Mentions: Imperial College London Leiden University University College London

    14. Correlation between in vivo near-infrared spectroscopy and optical coherence tomography detected lipid-rich plaques with post-mortem histology

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      Correlation between in vivo near-infrared spectroscopy and optical coherence tomography detected lipid-rich plaques with post-mortem histology
      A 67-year-old female presented with an acute anterior STEMI and underwent percutaneous coronary intervention of the mid-left anterior descending (LAD) coronary artery. Following successful implantation of two drug-eluting stents with TIMI III flow, multimodality imaging using near-infrared spectroscopy with intravascular ultrasound (NIRS-IVUS) and optical coherence tomography (OCT) was performed in the LAD and right coronary artery (RCA) in the setting of an imaging study (A1 and B1).
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      Mentions: University of Bern Bern University Hospital

    15. Expert-level Automated Biomarker Identification in Optical Coherence Tomography Scans

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      Expert-level Automated Biomarker Identification in Optical Coherence Tomography Scans
      In ophthalmology, retinal biological markers, or biomarkers , play a critical role in the management of chronic eye conditions and in the development of new therapeutics. While many imaging technologies used today can visualize these, Optical Coherence Tomography (OCT) is often the tool of choice due to its ability to image retinal structures in three dimensions at micrometer resolution. But with widespread use in clinical routine, and growing prevalence in chronic ...
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      Mentions: University of Bern

    16. Optical coherence tomography diagnostic signs in posterior uveitis

      Explore ScienceDirect Ophthalmology
      Optical coherence tomography diagnostic signs in posterior uveitis
      A diagnostic sign refers to a quantifiable biological parameter that is measured and evaluated as an indicator of normal biological, pathogenic, or pharmacologic responses to a therapeutic intervention. When used in translational research discussions, the term itself often alludes to a signs used to accelerate or aid in diagnosis or monitoring and provide insight into personalized medicine. Many new diagnostic signs are being developed that involve imaging technology. Optical coherence ...
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      Mentions: Case Western Reserve University Northwestern University University of Sydney
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