1. University of Auckland

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    1. Mentioned In 45 Articles

    2. Phenotype- and patient-specific modelling in asthma: bronchial thermoplasty and uncertainty quantification

      Phenotype- and patient-specific modelling in asthma: bronchial thermoplasty and uncertainty quantification
      Theoretical models can help to overcome experimental limitations to better our understanding of lung physiology and disease. While such efforts often begin in broad terms by determining the effect of a disease process on a relevant biological output, more narrowly defined simulations may inform clinical practice. Two such examples are phenotype-specific and patient-specific models, the former being specific to a group of patients with common characteristics, and the latter to ...
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    3. Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)

      Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)
      Quantum Optical Coherence Tomography (Q-OCT) is the non-classical counterpart of Optical Coherence Tomography (OCT) - a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of frequency-entangled photon pairs, not only is the axial resolution not affected by dispersion mismatch in the interferometer, but is also inherently improved by a factor of square root of two. Unfortunately, practical applications of QOCT are hindered by image-scrambling artefacts and ...
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    4. Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat

      Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat
      Significance: Imaging neural activity in myelinated tissue using optical coherence tomography (OCT) creates exciting possibilities for functional imaging in the peripheral and central nervous systems. Aim: To investigate changes in OCT images in response to evoked neural activity in sciatic nerve of rat in vitro. Approach: M-scans were obtained on peripheral nerves of rat using a swept source polarisation sensitive OCT system, while a nerve cuff acquired electrical neural recordings ...
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    5. Quantum-inspired detection for Spectral Domain Optical Coherence Tomography

      Quantum-inspired detection for Spectral Domain Optical Coherence Tomography
      The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve high-sensitivity imaging at low intensity levels, we adapt a detection scheme - which is used in quantum optics for providing information about spectral correlations of photons - into a standard spectral domain OCT system. This ...
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    6. Optical coherence tomography complements confocal microscopy for investigation of multicellular tumour spheroids

      Optical coherence tomography complements confocal microscopy for investigation of multicellular tumour spheroids
      Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous cells to drugs, optimised imaging protocols are required. This study uses a simple custom-built spectral domain optical coherence tomography (OCT) system to conduct RI measurements of multicellular spheroids, three-dimensional (3D) in-vitro culture systems, of ...
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    7. Refractive index measurements of multicellular tumour spheroids using optical coherence tomography: dependence on growth phase and size

      Refractive index measurements of multicellular tumour spheroids using optical coherence tomography: dependence on growth phase and size
      Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous cells to drugs, optimised imaging protocols are required. This study uses a simple custom-built spectral domain optical coherence tomography (OCT) system to conduct RI measurements of multicellular spheroids, three-dimensional in-vitro culture systems, of the ...
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    8. Effect of phacoemulsification incision size on incision repair and remodeling: Optical coherence tomography assessment

      Effect of phacoemulsification incision size on incision repair and remodeling: Optical coherence tomography assessment
      Purpose To characterize the effect of incision size on corneal incision repair and remodeling over 3 months after cataract surgery. Setting Department of Ophthalmology, Auckland District Health Board, Auckland, New Zealand. Design Prospective case series. Methods Eyes having routine cataract surgery were randomized to receive 2.20 mm or 2.85 mm uniplanar clear corneal incisions. Anterior segment optical coherence tomography of incision thickness, length, width, gaping, and angle and ...
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    9. Quantifying birefringence in the bovine model of early osteoarthritis using polarisation-sensitive optical coherence tomography and mechanical indentation

      Quantifying birefringence in the bovine model of early osteoarthritis using polarisation-sensitive optical coherence tomography and mechanical indentation
      Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and to be potentially used as an in vivo , non-invasive tool for detecting osteoarthritic changes. However, there has been relatively limited ability of this method to quantify the subtle changes that occur in the early stages of cartilage degeneration. An established mechanical indenting technique that has previously been used to examine the microstructural ...
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    10. Extracting morphometric information from rat sciatic nerve using optical coherence tomography

      Extracting morphometric information from rat sciatic nerve using optical coherence tomography
      We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological measurements accurate to +/-1 m. The three OCT techniques are: 1) average depth resolved profile (ADRP); 2) autoregressive spectral estimation (AR-SE); and, 3) correlation of the derivative spectral estimation (CoD-SE). We introduce a scanning window to the ADRP ...
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    11. Using polarisation-sensitive optical coherence tomography and mechanical indentation to assess cartilage degeneration in the bovine model of early osteoarthritis

      Using polarisation-sensitive optical coherence tomography and mechanical indentation to assess cartilage degeneration in the bovine model of early osteoarthritis
      Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and this presents a useful real-time non-invasive tool for detecting osteoarthritic changes. However, there has been relatively limited ability of this method to quantify the subtle changes in the early stages of joint degeneration. In this study, we investigate the ability of PS-OCT to detect microscale degenerative changes in cartilage, following compression, using ...
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    12. Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data

      Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data
      Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of blood flow or tissue elasticity. Minimal or no need for system alterations make functional OCT techniques useful in performing multimodal imaging, where differently contrasted images are produced in a single examination. We propose a method that further ...
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    13. Dispersion measurements in ocular media using a dual-wavelength swept source optical coherence tomography system

      Dispersion measurements in ocular media using a dual-wavelength swept source optical coherence tomography system
      Optical coherence tomography (OCT) has proved to be a powerful tool for the detection of microstructure in tissue. Label-free tissue differentiation on a micron scale is a promising and powerful technique for segmentation. This Letter describes a technique using a dual-wavelength OCT system to image the eye. We measure the walk-off between interfaces in A-scans, taken at two different wavelengths, to calculate the average group velocity dispersion parameter of each ...
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    14. 1-15 of 45 1 2 3 »
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  2. About University of Auckland

    University of Auckland

    University of Auckland is New Zealand's largest university and the top-ranked New Zealand university. Established in 1883 as a constituent college of the University of New Zealand, the university is now made up of eight faculties over six campuses, and has more than 39,000 students at April 2006.   Also see the Department of Physics at the University of Auckland.