1. University of Arizona

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    1. Mentioned In 111 Articles

    2. A group of 28 students affiliated with the University of Arizona has received the prestigious National Science Foundation Graduate Research Fellowship.

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      A group of 28 students affiliated with the University of Arizona has received the prestigious National Science Foundation Graduate Research Fellowship.
      David Vega , a doctoral student finishing his first year in the optical sciences program. Vega's research is based on early detection of ovarian cancer using optical coherence tomography and multiphoton microscopy. The breakthrough technologies he is developing are transferable to numerous applications and offer broad impacts in several other fields, ranging from other medical diagnostics to astronomy
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      Mentions: University of Arizona

    3. Measurement of the lipid and aqueous layers of a tear film

      Explore uspto.gov Ophthalmology , Patents
      Measurement of the lipid and aqueous layers of a tear film
      Systems and methods for determining thickness of lipid and aqueous layers of a tear film in which a spectrum array is generated from optical coherence tomography and input into a statistical estimator, which determines the thickness of the lipid and/or aqueous layers at a nanometer resolution based on the inputted spectrum and other information, such as information about a laser intensity noise, Poisson noise, and dark noise associated with ...
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      Mentions: University of Rochester University of Arizona Jannick P. Rolland

    4. Single lens system for forward-viewing navigation and scanning side-viewing optical coherence tomography

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      Single lens system for forward-viewing navigation and scanning side-viewing optical coherence tomography
      The optical design for a dual modality endoscope based on piezo scanning fiber technology is presented including a novel technique to combine forward-viewing navigation and side viewing OCT. Potential applications include navigating body lumens such as the fallopian tube, biliary ducts and cardiovascular system. A custom cover plate provides a rotationally symmetric double reflection of the OCT beam to deviate and focus the OCT beam out the side of the ...
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      Mentions: Jennifer K. Barton University of Arizona

    7. In vivo endoscopic Doppler optical coherence tomography imaging of the colon

      Explore Wiley Online Library Gastroenterology , Oncology
      In vivo endoscopic Doppler optical coherence tomography imaging of the colon
      Background and Objective Colorectal cancer (CRC) remains the second deadliest cancer in the United States. Several screening methods exist; however, detection of small polyps remains a challenge. Optical coherence tomography (OCT) has been demonstrated to be capable of detecting lesions as small as 1mm in the mouse colon, but detection is based on measuring a doubling of the mucosa thickness. The colon microvasculature may be an attractive biomarker of early ...
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      Mentions: Jennifer K. Barton University of Arizona

    10. Optical coherence tomography imaging of colonic crypts in a mouse model of colorectal cancer

      Explore Conference Proceedings Developmental Biology , Gastroenterology
      Optical coherence tomography imaging of colonic crypts in a mouse model of colorectal cancer
      Aberrant crypt foci (ACF) are abnormal epithelial lesions that precede development of colonic polyps. As the earliest morphological change in the development of colorectal cancer, ACF is a highly studied phenomenon. The most common method of imaging ACF is chromoendoscopy using methylene blue as a contrast agent. Narrow- band imaging is a contrast-agent-free modality for imaging the colonic crypts. Optical coherence tomography (OCT) is an attractive alternative to chromoendoscopy and ...
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      Mentions: Jennifer K. Barton University of Arizona

    11. In vivo endoscopic Doppler optical coherence tomography imaging of mouse colon

      Explore Conference Proceedings Gastroenterology
      In vivo endoscopic Doppler optical coherence tomography imaging of mouse colon
      Colorectal cancer remains the second deadliest cancer in the United States, despite the high sensitivity and specificity of colonoscopy and sigmoidoscopy. While these standard imaging procedures can accurately detect medium and large polyps, some studies have shown miss rates up to 25% for polyps less than 5 mm in diameter. An imaging modality capable of detecting small lesions could potentially improve patient outcomes. Optical coherence tomography (OCT) has been shown ...
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      Mentions: Jennifer K. Barton University of Arizona

    12. Imaging colon cancer development in mice: IL-6 deficiency prevents adenoma in azoxymethane-treated Smad3 knockouts

      Explore IOPscience Gastroenterology
      Imaging colon cancer development in mice: IL-6 deficiency prevents adenoma in azoxymethane-treated Smad3 knockouts
      The development of colorectal cancer in the azoxymethane-induced mouse model can be observed by using a miniaturized optical coherence tomography (OCT) imaging system. This system is uniquely capable of tracking disease development over time, allowing for the monitoring of morphological changes in the distal colon due to tumor development and the presence of lymphoid aggregates. By using genetically engineered mouse models deficient in Interleukin 6 (IL-6) and Smad family member ...
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      Mentions: Jennifer K. Barton University of Arizona Photini F. S. Rice

    13. Temporal Trends in Strut-Level Optical Coherence Tomography Evaluation of Coronary Stent Coverage

      Explore Wiley Online Library Cardiology
      Temporal Trends in Strut-Level Optical Coherence Tomography Evaluation of Coronary Stent Coverage
      Objectives We sought to pool data from all studies with reported strut-level data in human subjects evaluated by optical coherence tomography (OCT) surveillance and to compare the aggregate data of stent strut coverage on a longitudinal temporal timeline from initial implantation for different coronary stent subtypes. Background Delayed strut coverage following drug-eluting stent (DES) implantation is an important contributor to late stent thrombosis (LST). OCT can detect stent strut coverage ...
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      Mentions: Emory University University of Arizona Habib Samady

    14. Methods of Melanoma Detection

      Explore Home - Springer Dermatology
      Methods of Melanoma Detection
      Detection and removal of melanoma, before it has metastasized, dramatically improves prognosis and survival. The purpose of this chapter is to (1) summarize current methods of melanoma detection and (2) review state-of-the-art detection methods and technologies that have the potential to reduce melanoma mortality. Current strategies for the detection of melanoma range from population-based educational campaigns and screening to the use of algorithm-driven imaging technologies and performance of assays that ...
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      Mentions: Massachusetts General Hospital Oregon Health & Science University Stanford University

    15. Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope

      Explore Journals | PLOS Probes
      Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope
      Optical coherence tomography (OCT) is a useful imaging modality for detecting and monitoring diseases of the gastrointestinal tract and other tubular structures. The non-destructiveness of OCT enables time-serial studies in animal models. While turnkey commercial research OCT systems are plenty, researchers often require custom imaging probes. We describe the integration of a custom endoscope with a commercial swept-source OCT system and generalize this description to any imaging probe and OCT ...
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      Mentions: Jennifer K. Barton University of Arizona

    16. In vivo molecular imaging of colorectal cancer using quantum dots targeted to vascular endothelial growth factor receptor 2 and optical coherence tomography/laser-induced fluorescence dual-modality imaging

      Explore SPIE | Journal Gastroenterology
      In vivo molecular imaging of colorectal cancer using quantum dots targeted to vascular endothelial growth factor receptor 2 and optical coherence tomography/laser-induced fluorescence dual-modality imaging
      Optical coherence tomography/laser induced fluorescence (OCT/LIF) dual-modality imaging allows for minimally invasive, nondestructive endoscopic visualization of colorectal cancer in mice. This technology enables simultaneous longitudinal tracking of morphological (OCT) and biochemical (fluorescence) changes as colorectal cancer develops, compared to current methods of colorectal cancer screening in humans that rely on morphological changes alone. We have shown that QDot655 targeted to vascular endothelial growth factor receptor 2 (QD655-VEGFR2) can ...
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      Mentions: Jennifer K. Barton University of Arizona Urs Utzinger
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  4. About University of Arizona

    University of Arizona

    University of Arizona is a public institution of higher education and research located in Tucson, Arizona, United States. The University of Arizona was the first university in the state of Arizona, founded in 1885. The Tissue Optics Laboratory is an interdisciplinary effort located at the University of Arizona in the Keating Biosciences Building of the BIO5 Institute.  The Arizona Cancer Center is part of the University of Arizona.

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