1. University of Alabama

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    1. Mentioned In 90 Articles

    2. Unveiling idiopathic macular telangiectasia: clinical applications of optical coherence tomography angiography

      Unveiling idiopathic macular telangiectasia: clinical applications of optical coherence tomography angiography
      Idiopathic macular telangiectasia type 2 (IMT2) is a bilateral acquired maculopathy, with a spectrum of clinical presentations associated with inner retinal telangiectatic vascular anomalies. Cases often are underdiagnosed or misdiagnosed. Current diagnostic modalities such as spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) are valuable to the understanding of the clinicopathology. More recently, optical coherence tomography angiography (OCTA), as an emerging noninvasive technology, has been shown to be particularly ...
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    3. The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy

      The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy
      Purpose : Histologic details of progression routes to geographic atrophy (GA) in AMD are becoming available through optical coherence tomography (OCT). We studied the origins and evolution of an OCT signature called plateau in eyes with GA and suggested a histologic correlate. Methods : Serial eye-tracked OCT scans and multimodal imaging were acquired from eight eyes of seven patients with GA and plateau signatures over a mean follow-up of 7.7 years ...
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    4. University of Illinois at Chicago Receives NIH Grant for Functional Imaging of Retinal Photoreceptors

      University of Illinois at Chicago Receives NIH Grant  for Functional Imaging of Retinal Photoreceptors
      ...aluation of retinal physiology is important for early disease detection and reliable treatment management. At University of Alabama at Birmingham (UAB), we have developed several optical approaches, including functional ...
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    5. Quantifying the effects of UV-A/riboflavin crosslinking on the elastic anisotropy and hysteresis of the porcine cornea by noncontact optical coherence elastography

      Quantifying the effects of UV-A/riboflavin crosslinking on the elastic anisotropy and hysteresis of the porcine cornea by noncontact optical coherence elastography
      The collagen fibril orientation of the cornea can provide critical information about cornea tissue health because diseases such as keratoconus and therapeutic interventions such as UV-A/riboflavin corneal collagen crosslinking (CXL) can alter the ultrastructural arrangement of collagen fibrils. Here, we quantify the elastic anisotropy and hysteresis of in situ porcine corneas as a function of intraocular pressure (IOP) with noncontact optical coherence elastography. Moreover, the effects of UV-A riboflavin ...
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    6. Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia

      Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia
      We report the design and fabrication of a flexible, longitudinally scanning high-resolution micro-optical coherence tomography (OCT) endobronchial probe, optimized for micro-anatomical imaging in airways. The 2.4 mm diameter and flexibility of the probe allows it to be inserted into the instrument channel of a standard bronchoscope, enabling real-time video guidance of probe placement. To generate a depth-of-focus enhancing annular beam, we utilized a new fabrication method, whereby a hollow ...
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    7. Histologic and Optical Coherence Tomographic Correlates in Drusenoid Pigment Epithelium Detachment in Age-Related Macular Degeneration

      Histologic and Optical Coherence Tomographic Correlates in Drusenoid Pigment Epithelium Detachment in Age-Related Macular Degeneration
      Purpose Drusenoid pigment epithelium detachment (DPED) is a known precursor to geographic atrophy in age-related macular degeneration (AMD). We sought histologic correlates for spectral-domain (SD) optical coherence tomography (OCT) signatures in DPED and determined the frequency and origin of these OCT signatures in a clinical cohort of DPED eyes. Design Laboratory imaging and histologic comparison, and retrospective, observational cohort study. Participants Four donor eyes with histopathologic diagnosis of AMD (2 ...
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    8. Evaluation of Segmentation of the Superficial and Deep Vascular Layers of the Retina By Optical Coherence Tomography Angiography Instruments in Normal Eyes

      Evaluation of Segmentation of the Superficial and Deep Vascular Layers of the Retina By Optical Coherence Tomography Angiography Instruments in Normal Eyes
      Importance Correct attribution of vascular features in optical coherence tomography (OCT) angiography depends on accurate segmentation of retinal layers. Objective To evaluate the segmentation of retinal layers among 3 OCT angiography instruments in the central macula, an area where the superficial and deep vascular plexuses terminate. Design, Setting, and Participants A retrospective review of a representative OCT angiogram from 1 patient and an evaluation of the vascular pattern in an ...
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    9. University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease
      University of Alabam at Birmingham Receives a 2017 NIH Grant for $330,750 for In Vivo Ultrastruture of Chorioretinal Disease. The principal investigator is Yuhua Zhang. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a leading cause of vision loss in more than 10 million older Americans. For decades, AMD has been characterized by accumulation of ...
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    10. Assessing the effects of riboflavin/UV-A crosslinking on porcine corneal mechanical anisotropy with optical coherence elastography

      Assessing the effects of riboflavin/UV-A crosslinking on porcine corneal mechanical anisotropy with optical coherence elastography
      In this work we utilize optical coherence elastography (OCE) to assess the effects of UV-A/riboflavin corneal collagen crosslinking (CXL) on the mechanical anisotropy of in situ porcine corneas at various intraocular pressures (IOP). There was a distinct meridian of increased Youngs modulus in all samples, and the mechanical anisotropy increased as a function of IOP and also after CXL. The presented noncontact OCE technique was able to quantify the ...
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    11. OCT Expanded Clinical Data Analysis (OCT Aboard Space Station)

      OCT Expanded Clinical Data Analysis (OCT Aboard Space Station)
      Vision changes identified in long duration space fliers has led to a more comprehensive clinical monitoring protocol. Optical Coherence Tomography (OCT) was recently implemented on board the International Space Station in 2013. NASA is collaborating with Heidelberg Engineering to expand our current OCT data analysis capability by implementing a volumetric approach. Volumetric maps will be created by combining the circle scan, the disc block scan, and the radial scan. This ...
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  2. About University of Alabama

    University of Alabama

    The University of Alabama (also known as Alabama, UA, or colloquially as 'Bama) is a public coeducational university located in Tuscaloosa, Alabama, USA. Founded in 1831, UA is the flagship school of the University of Alabama System. Within Alabama, it is often called the Capstone. UA is the senior and the largest in terms of enrollment of the state's major research universities, the others being academic and athletic rival Auburn University and fellow UA System institutions the University of Alabama in Huntsville (UAH) and the University of Alabama at Birmingham (UAB). Outside the state, it is well known for the fact that its athletic teams are nicknamed the "Crimson Tide" (crimson being one of the school colors).   The University of Alabama offers programs of study in 12 academic divisions leading to bachelor's, master's, Education Specialist, and doctoral degrees. The only publicly-supported law school in Alabama is at UA. Other academic programs unavailable elsewhere in Alabama include doctoral programs in anthropology, library and information studies, metallurgical and material engineering, music, Romance languages, and social work.  As of fall 2007, Alabama has an enrollment of 25,580 students and its president is Dr. Robert Witt. The University of Alabama has the highest ranking in the 2008 edition of the US News and World Report: America's Best Colleges of any university in the state of Alabama."