1. University Medical Center Utrecht

    0 Comments Leave a Comment

    1-15 of 21 1 2 »
    1. Mentioned In 21 Articles

    2. Automatic evaluation of graft orientation during Descemet membrane endothelial keratoplasty using intraoperative OCT

      Automatic evaluation of graft orientation during Descemet membrane endothelial keratoplasty using intraoperative OCT
      Correct Descemet Membrane Endothelial Keratoplasty (DMEK) graft orientation is imperative for success of DMEK surgery, but intraoperative evaluation can be challenging. We present a method for automatic evaluation of the graft orientation in intraoperative optical coherence tomography (iOCT), exploiting the natural rolling behavior of the graft. The method encompasses a deep learning model for graft segmentation, post-processing to obtain a smooth line representation, and curvature calculations to determine graft orientation ...
      Read Full Article
    3. Bilateral posterior lamellar corneal transplant surgery in an infant of 17 weeks old: Surgical challenges and the added value of intraoperative optical coherence tomography

      Bilateral posterior lamellar corneal transplant surgery in an infant of 17 weeks old: Surgical challenges and the added value of intraoperative optical coherence tomography
      This study aimed to describe the surgical challenges, management, and value of intraoperative optical coherence tomography in a case of a bilateral Descemet Stripping Automated Endothelial Keratoplasty corneal transplantation at 17 weeks of age for the treatment of severe posterior polymorphous corneal dystrophy resulting from a de novo mutation of the OVOL2-gene.
      Read Full Article
    4. Image-guided surgery in oral cancer: toward improved margin control

      Image-guided surgery in oral cancer: toward improved margin control
      Purpose of review The aim of this review is to discuss recent studies on the assessment of tumor extension and resection margins by different intraoperative techniques allowing for image-guided surgery of oral cancer. Recent findings There are different in-vivo and ex-vivo intraoperative techniques to improve margin control of which intraoperative ultrasound and targeted fluorescence-guided resections have high potential clinical value and are closest to clinical implementation. Summary In oral cancer ...
      Read Full Article
    5. Clinical applications for intraoperative optical coherence tomography: a systematic review

      Clinical applications for intraoperative optical coherence tomography: a systematic review
      In this systematic review, we provide an overview of the current state of intraoperative optical coherence tomography (iOCT). As iOCT technology is increasingly utilized, its current clinical applications and potential uses warrant attention. Here, we categorize the findings of various studies by their respective fields, including the use of iOCT in vitreoretinal surgery, corneal surgery, glaucoma surgery, cataract surgery, and pediatric ophthalmology. The trend observed in recent decades towards performing ...
      Read Full Article
    6. Visual impairment in children with a brain tumor: a prospective nationwide multicenter study using standard visual testing and optical coherence tomography (CCISS study)

      Visual impairment in children with a brain tumor: a prospective nationwide multicenter study using standard visual testing and optical coherence tomography (CCISS study)
      Background Children with a brain tumor have a high risk of impaired vision. Up to now, visual acuity measurement, visual field testing and orthoptic testing are the most informative diagnostic investigations for the assessment of visual function. Evaluating vision in children can be challenging given the challenges in cooperation, concentration and age-dependent shifts in visual tests. Since visual loss due to a brain tumor can be progressive and irreversible, we ...
      Read Full Article
    7. Micro-indentation and optical coherence tomography for the mechanical characterization of embryos: Experimental setup and measurements on fixed chicken embryos.

      Micro-indentation and optical coherence tomography for the mechanical characterization of embryos: Experimental setup and measurements on fixed chicken embryos.
      The investigation of the mechanical properties of embryos is expected to provide valuable information on the phenomenology of morphogenesis. It is thus believed that, by mapping the viscoelastic features of an embryo at different stages of growth, it may be possible to shed light on the role of mechanics in embryonic development. To contribute to this field, we present a new instrument that can determine spatiotemporal distributions of mechanical properties ...
      Read Full Article
    8. Micro-indentation and optical coherence tomography for the mechanical characterization of embryos

      Micro-indentation and optical coherence tomography for the mechanical characterization of embryos
      The investigation of the mechanical properties of embryos is expected to provide valuable information on the phenomenology of morphogenesis. It is thus believed that, by mapping the viscoelastic features of an embryo at different stages of growth, it may be possible to shed light on the role of mechanics in embryonic development. To contribute to this field, we present a new instrument that can determine spatiotemporal distributions of mechanical properties ...
      Read Full Article
    9. Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure

      Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure
      Conventional arthroscopic evaluation of articular cartilage is subjective and poorly reproducible. Therefore, implementation of quantitative diagnostic techniques, such as near infrared spectroscopy (NIRS) and optical coherence tomography (OCT), is essential. Locations ( n =44) with various cartilage conditions were selected from mature equine fetlock joints ( n =5). These locations and their surroundings were measured with NIRS and OCT ( n =530). As a reference, cartilage proteoglycan (PG) and collagen contents, and collagen ...
      Read Full Article
    10. Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis

      Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis
      Objectives This study sought to determine whether indocyanine green (ICG)enhanced near-infrared fluorescence (NIRF) imaging can illuminate high-risk histologic plaque features of human carotid atherosclerosis, and in coronary atheroma of living swine, using intravascular NIRF-optical coherence tomography (OCT) imaging. Background New translatable imaging approaches are needed to identify high-risk biological signatures of atheroma. ICG is a U.S. Food and Drug Administrationapproved NIRF imaging agent that experimentally targets plaque macrophages ...
      Read Full Article
    11. Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound

      Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound
      Background and purpose Arthroscopic estimation of articular cartilage thickness is important for scoring of lesion severity, and measurement of cartilage speed of sound (SOS)a sensitive index of changes in cartilage composition. We investigated the accuracy of optical coherence tomography (OCT) in measurements of cartilage thickness and determined SOS by combining OCT thickness and ultrasound (US) time-of-flight (TOF) measurements. Material and methods Cartilage thickness measurements from OCT and microscopy images ...
      Read Full Article
    12. Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging

      Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging
      ...l and Massachusetts General Hospital, Boston, MA, USA Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands Department of Biomedical Engineering, Boston Univ...
      Read Full Article
    13. Serial Morphological and Functional Assessment of Drug-Eluting Balloon for In-Stent Restenotic Lesions : Mechanisms of Action Evaluated With Angiography, Optical Coherence Tomography, and Fractional Flow Reserve

      Serial Morphological and Functional Assessment of Drug-Eluting Balloon for In-Stent Restenotic Lesions : Mechanisms of Action Evaluated With Angiography, Optical Coherence Tomography, and Fractional Flow Reserve
      ... M. Nathoe, MD, PhD, * Pieter A. Doevendans, MD, PhD, * Pieter R. Stella, MD, PhD * Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands Received 3 December 2012 Revised 14 December 2012 ...
      Read Full Article
    14. Intravascular optical coherence tomography imaging at 3200 frames per second

      Intravascular optical coherence tomography imaging at 3200 frames per second
      We demonstrate intravascular optical coherence tomography (OCT) imaging with frame rate up to 3.2 kHz (192,000 rpm scanning). This was achieved by using a custom-built catheter in which the circumferential scanning was actuated by a 1.0 mm diameter synchronous motor. The OCT system, with an imaging depth of 3.7 mm (in air), is based on a Fourier domain mode locked laser operating at an A-line rate ...
      Read Full Article
    15. Optimizing the Information Yield of 3-D OCT in Glaucoma

      Optimizing the Information Yield of 3-D OCT in Glaucoma
      Purpose. To determine, first, which regions of 3-D optical coherence tomography (OCT) volumes can be segmented completely in the majority of subjects and, second, the relationship between analyzed area and thickness measurement testretest variability. Methods. Three-dimensional OCT volumes (6 6 mm) centered around the fovea and optic nerve head (ONH) of 925 Rotterdam Study participants were analyzed; 44 participants were scanned twice. Volumes were segmented into 10 layers, and we ...
      Read Full Article
    16. 1-15 of 21 1 2 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About University Medical Center Utrecht

    University Medical Center Utrecht

    University Medical Center Utrecht or UMCU is the main hospital of the city of Utrecht . It is affiliated with the Utrecht University . Since the foundation of the university in 1636 an academic hospital has existed in various forms. Nowadays the UMC Utrecht comprises the academic hospital, the faculty of Medicine as well as the Wilhelmina Children's hospital. In total approximately 10,000 people work at the UMCU including medical staff, nursing staff, residents, support personnel and researchers, making it one of the largest hospitals in the Netherlands. Special units include: * Neurosurgery * Cardiothoracic surgery * Neonatal and pediatric surgery and intensive care * Pediatric oncology * Level I trauma center Adjacent to the UMCU lies an underground military facility known as the Centraal Militair Hospitaal (Central Military Hospital), or CMH. This facility is also occasionally used in peacetime for treating groups of patients in case of major catastrophes or who might have been infected with contagious diseases (for example, repatriated wounded Dutch citizens after the 2004 Indian Ocean earthquake and tsunami) .