1. University College London

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    1. Mentioned In 215 Articles

    2. Optical coherence tomography of the tongue papillae for patients suffering from taste disorders following chemoradiotherapy

      Optical coherence tomography of the tongue papillae for patients suffering from taste disorders following chemoradiotherapy
      ...Head and Neck Surgery, Barnet and Chase Farm Hospitals NHS Trust, United Kingdom 2 UCL Department of Surgery, University College London Medical School, United Kingdom PII: S1572-1000(11)00362-0 doi:10.1016/j.pdpdt.2011.0...
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    3. First published application of Optical Coherence Tomography for in vivo mapping of non-melanoma skin cancer

      First published application of Optical Coherence Tomography for in vivo mapping of non-melanoma skin cancer
      Michelson Diagnostics Press Release: A case study performed at University College Hospital London documenting the successful use of Michelson Diagnostics’ VivoSight OCT scanner for in vivo mapping of non-melanoma skin cancer, has been published in the March 2011 issue of Photodiagnosis and Photodynamic Therapy1.   The key benefit of Photodynamic Therapy (PDT) of non-melanoma skin cancers over conventional surgical excision is that it is non-invasive and therefore avoids surgery scars. This ...
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    4. Optical coherence tomography-guided photodynamic therapy for skin cancer: Case study

      Optical coherence tomography-guided photodynamic therapy for skin cancer: Case study
      Photodynamic therapy (PDT) has been identified as a successful therapy for skin cancer. This case study investigates the role of optical coherence tomography (OCT) in lesion (squamous cell carcinoma) mapping, assisting the surgeon to correctly deliver PDT and monitor the outcome. Optical coherence tomographic images were acquired pre-treatment to assess tumour extent and margins to enable guidance of the PDT. Tomographic images taken post-PDT up to 6 months revealed complete ...
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    5. Current Munich status concerning in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract

      Current Munich status concerning in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract
      Objective Non-invasive differentiation of pre- and early malignant mucosal changes may be helpful to reduce the morbidity and shorten the time to diagnosis for the patients concerned. Optical Coherence Tomography (OCT) seems to be well suited to reach this goal. Methods 61 patients with a total of 82 primary leukoplakic or erythroplakic mucosal lesions of the upper aerodigestive tract (OADT) were prospectively examined using an in-vivo, time-domain OCT (Niris®, Imalux ...
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    6. Assessment of tumour resection margins using optical coherence tomography

      Assessment of tumour resection margins using optical coherence tomography
      In the treatment of cancer, the fundamental surgical goal is to remove all local malignant disease and leave no residual malignant cells. Studies have demonstrated the benefit of achieving negative resection margins in terms of disease free local recurrence and overall survival. The surgical margins for head & neck cancer may vary widely depending on the site of disease. Optical coherence tomography (OCT) is an imaging modality that uses light to ...
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    7. Assessment of suspicious oral lesions using optical coherence tomography

      Assessment of suspicious oral lesions using optical coherence tomography
      Introduction/aims Optical biopsy systems have been investigated for various clinical applications; however the main interest remains in the diagnosis and monitoring of premalignant and malignant conditions. In this study, we compared findings of optical coherence tomography (OCT) with histopathology results of suspicious oral lesions to assess the feasibility of OCT in identifying pathological tissue. Material/methods Suspicious oral lesions acquired from 120 patients were subjected to immediate ex-vivo Swept-Source ...
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    8. Aligning Scan Acquisition Circles in Optical Coherence Tomography Images of The Retinal Nerve Fibre Layer

      Aligning Scan Acquisition Circles in Optical Coherence Tomography Images of The Retinal Nerve Fibre Layer
      Optical coherence tomography (OCT) is widely used in the assessment of retinal nerve fibre layer thickness (RNFLT) in glaucoma. Images are typically acquired with a circular scan around the optic nerve head. Accurate registration of OCT scans is essential for measurement reproducibility and longitudinal examination. This study developed and evaluated a special image registration algorithm to align the location of the OCT scan circles to the vessel features in the ...
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    9. Acute Severe Visual Decrease After Photodynamic Therapy With Verteporfin: Spectral-Domain OCT Features

      Acute Severe Visual Decrease After Photodynamic Therapy With Verteporfin: Spectral-Domain OCT Features
      In this report, spectral-domain optical coherence tomography (OCT) was used to characterize the acute morphologic alterations that occur when photodynamic therapy with verteporfin results in an acute severe visual decrease. The clinical and imaging records of a patient with neovascular age-related macular degeneration who suffered this complication were reviewed. Using spectral-domain OCT, two relatively distinct subretinal fluid compartments were visualized: a sparsely hyperreflective pocket of subretinal fluid overlying the fibrovascular ...
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    10. Introduction: Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy

      Introduction: Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy
      The editors introduce the Biomedical Optics Express feature issue, “Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy,” which combines three technical areas from the 2010 Optical Society of America (OSA), Biomedical Optics (BIOMED) Topical Meeting held on 11–14 April in Miami, Florida, and includes contributions from conference attendees.
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    11. Demonstration of the time course of retrograde trans-synaptic degeneration in the visual system using optical coherence tomography

      Demonstration of the time course of retrograde trans-synaptic degeneration in the visual system using optical coherence tomography
      26 patients were recruited following acute unilateral damage to the postgeniculate visual pathway (onset 12–50 years prior to testing) together with age and sex matched controls. Peripapillary retinal nerve fibre layer (RNFL) thickness was measured with optical coherence tomography on a single occasion. (2) 7 of the 26 patients and a further 4 patients with incomplete hemianopia were recruited within 5 months of the injury (range 5–177 days ...
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    12. 181-195 of 215 « 1 2 ... 10 11 12 13 14 15 »
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  2. About University College London

    University College London

    University College London is the oldest multi-faculty constituent college of the University of London and is one of the two original founding colleges. With 21,800 staff and students, UCL is one of the largest colleges of the University and is larger than most other universities in the United Kingdom. The Department of Medical Physics and Bioengineering has been for many years a joint department of University College London (UCL) and the UCL Hospitals Trust (UCLH).