1. University College London

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    1. Mentioned In 205 Articles

    2. Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic le

      Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic le
      Aims: Durable polymer drug-eluting stents (DP-DES) may contribute to persistent inflammation, delayed endothelial healing and subsequent late DES thrombosis. The aim of this optical coherence tomography (OCT) substudy was to compare healing and neointimal coverage of a novel bioabsorbable polymer sirolimus-eluting stent (Firehawk ) (BP-DES) versus the DP-DES (XIENCE) at 90 days in an all-comers patient population. Methods and results: The TARGET All Comers study is a prospective multicentre randomised post-market ...
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    3. The International Multiple Sclerosis Visual System Consortium: Advancing Visual System Research in Multiple Sclerosis

      The International Multiple Sclerosis Visual System Consortium: Advancing Visual System Research in Multiple Sclerosis
      ...ork University School of Medicine, New York University, New York, New York; and Department of Neurology (AP), University College London, the National Hospital for Neurology and Neurosurgery, Moorfields Eye Hospital, Lond...
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    4. A flow cytometric and optical coherence analysis of the role of microparticles as determinants of plaque instability in acute coronary syndrome (FOAM study) (Thesis)

      A flow cytometric and optical coherence analysis of the role of microparticles as determinants of plaque instability in acute coronary syndrome (FOAM study) (Thesis)
      Introduction: Microparticles (MPs) are implicated in the pathogenesis of coronary artery disease (CAD). / Aims: To determine whether circulating MPs correlate with high-risk coronary atherosclerotic plaque phenotype. / Methods: 25 patients with CAD undergoing percutaneous coronary intervention (PCI) were recruited; 13 were diagnosed to have acute coronary syndrome (ACS) 12 with stable angina (SA). We characterized and compared coronary atherosclerotic plaque burden and vulnerable plaque phenotype by three-vessel optical coherence tomography (OCT ...
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    5. The diagnostic value of optical coherence tomography angiography in diabetic retinopathy: a systematic review

      The diagnostic value of optical coherence tomography angiography in diabetic retinopathy: a systematic review
      Purpose Diabetic retinopathy (DR) is one of the leading causes of blindness worldwide. Accurate investigative tools are essential for the early diagnosis and monitoring of the disease. Optical coherence tomography angiography (OCTA) is a recently developed technology that enables visualisation of the retinal microvasculature. Methods A systematic review of the literature was performed to examine the diagnostic use of OCTA in DR to date. Medline, EMBASE, and Cochrane databases were ...
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    6. Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning

      Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning
      Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular edema. However, center-involved diabetic macular edema is diagnosed using optical coherence tomography (OCT), which is not generally available at screening sites because of cost and workflow constraints. Instead, screening programs rely on the detection of hard exudates ...
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    7. Artificial intelligence and deep learning in ophthalmology

      Artificial intelligence and deep learning in ophthalmology
      Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc ...
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    8. Clinically applicable deep learning for diagnosis and referral in retinal disease

      Clinically applicable deep learning for diagnosis and referral in retinal disease
      The volume and complexity of diagnostic imaging is increasing at a pace faster than the availability of human expertise to interpret it. Artificial intelligence has shown great promise in classifying two-dimensional photographs of some common diseases and typically relies on databases of millions of annotated images. Until now, the challenge of reaching the performance of expert clinicians in a real-world clinical pathway with three-dimensional diagnostic scans has remained unsolved. Here ...
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    9. Now Google's DeepMind's AI can spot eye disease just as well as your doctor

      Now Google's DeepMind's AI can spot eye disease just as well as your doctor
      When Pearse Keane started using optical coherence tomography (OCT) scanners to peer to the back of a person's eye in Los Angeles a decade ago, the machines were relatively crude. "The devices were lower resolution, they had much slower image acquisition speeds," says Keane, a consultant ophthalmic surgeon at Moorfields Eye Hospital and researcher at University College, London. From 2007, Keane spent two years studying scans from OCT machines ...
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    10. Swept‐source optical coherence tomography angiography features of subretinal fibrosis in neovascular age‐related macular degeneration

      Swept‐source optical coherence tomography angiography features of subretinal fibrosis in neovascular age‐related macular degeneration
      Importance The study highlights the role of Optical Coherence Angiography in the management of patients with neovascular age‐related macular degeneration who have developed subretinal fibrosis. Background Development of subretinal fibrosis in the context of neovascular age‐related macular degeneration is known to adversely affect visual function. The aim of this study is to assess structure and flow features obtained through swept‐source optical coherence tomography angiography in patients with ...
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    11. All-optical dual photoacoustic and optical coherence tomography intravascular probe

      All-optical dual photoacoustic and optical coherence tomography intravascular probe
      Intravascular imaging in percutaneous coronary interventions can be an invaluable tool in the treatment of coronary artery disease. It is of significant interest to provide molecular imaging contrast that is complementary to structural contrast provided by optical coherence tomography (OCT) and intravascular ultrasound imaging (IVUS). In this study, we developed a dual-modality intravascular imaging probe comprising a commercial OCT catheter and a high sensitivity fiber optic ultrasound sensor, to provide ...
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    12. Two PhD Studentships in Medical Physics & Biomedical Engineering at the University College London

      Two PhD Studentships in Medical Physics & Biomedical Engineering at the University College London
      A four year PhD studentship funded by the Royal Society is available to embark on an exciting project developing a computational platform for application in cutting edge biomedical imaging techniques, including optical coherence tomography and photoacoustic tomography. This project has two primary aims: to significantly increase the volumes of tissue within which light propagation can be modelled and to apply this model to address current challenges in biomedical imaging. The ...
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    13. 1-15 of 205 1 2 3 4 ... 12 13 14 »
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  2. About University College London

    University College London

    University College London is the oldest multi-faculty constituent college of the University of London and is one of the two original founding colleges. With 21,800 staff and students, UCL is one of the largest colleges of the University and is larger than most other universities in the United Kingdom. The Department of Medical Physics and Bioengineering has been for many years a joint department of University College London (UCL) and the UCL Hospitals Trust (UCLH).