1. Universität Rostock

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    1. Mentioned In 25 Articles

    2. Enhanced Grid-Based Visual Analysis of Retinal Layer Thickness with Optical Coherence Tomography

      Enhanced Grid-Based Visual Analysis of Retinal Layer Thickness with Optical Coherence Tomography
      Optical coherence tomography enables high-resolution 3D imaging of retinal layers in the human eye. The thickness of the layers is commonly assessed to understand a variety of retinal and systemic disorders. Yet, the thickness data are complex and currently need to be considerably reduced prior to further processing and analysis. This leads to a loss of information on localized variations in thickness, which is important for early detection of certain ...
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    3. First Report of Edge Vascular Response at 12 Months of Magmaris, A Second-Generation Drug-Eluting Resorbable Magnesium Scaffold, Assessed by Grayscale Intravascular Ultrasound, Virtual Histology, and Optical Coherence Tomography. A Biosolve-II Trial Sub-S

      First Report of Edge Vascular Response at 12 Months of Magmaris, A Second-Generation Drug-Eluting Resorbable Magnesium Scaffold, Assessed by Grayscale Intravascular Ultrasound, Virtual Histology, and Optical Coherence Tomography. A Biosolve-II Trial Sub-S
      Introduction and objective The edge vascular response (EVR) remains unknown in second generation drug-eluting Resorbable Magnesium Scaffold (RMS), such as Magmaris. The aim of the study was to evaluate tissue modifications in the RMS edges over time, assessed by different invasive imaging modalities. Methods The patients treated with the device were assessed by optical coherence tomography (OCT), grayscale intravascular ultrasound (IVUS), and virtual histology IVUS at baseline and 12 months ...
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    4. In vivo corneal confocal microscopy aided by optical coherence tomography

      In vivo corneal confocal microscopy aided by optical coherence tomography
      In vivo corneal confocal microscopy and its operability in scientific as well as in clinical applications is often impaired by the lack of information on imaging plane position and orientation inside the cornea during patients examination. To overcome this hurdle, we have developed a novel corneal imaging system based on a commercial scanning device and a modified Rostock Cornea Module. The presented preliminary system produces en face images by confocal ...
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    5. Optical coherence tomography and confocal laser scanning microscopy as non-invasive tools in the diagnosis of sinonasal inverted papilloma: a pilot study

      Optical coherence tomography and confocal laser scanning microscopy as non-invasive tools in the diagnosis of sinonasal inverted papilloma: a pilot study
      Optical coherence tomography (OCT) and confocal laser scanning microscopy (CLSM) are light-based imaging techniques that allow for a visualization of microscopic tissue properties in vivo. Our study was to examine whether they allow for differentiation of inverted papilloma (IP) from nasal polyps (NP). Five cases of IP and NP, respectively, were investigated intraoperatively with OCT and CLSM. Biopsies were taken of the investigated area and were analyzed ex vivo with ...
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    6. Comparative study of presurgical skin infiltration depth measurements of melanocytic lesions with OCT and high frequency ultrasound

      Comparative study of presurgical skin infiltration depth measurements of melanocytic lesions with OCT and high frequency ultrasound
      A reliable, fast, and non-invasive determination of melanoma thickness in vivo is highly desirable for clinical dermatology as it may facilitate the identification of surgical melanoma margins, determine if a sentinel node biopsy should be performed or not, and reduce the number of surgical interventions for patients. In this work, optical coherence tomography (OCT) and high frequency ultrasound (HFUS) are evaluated for quantitative in vivo preoperative assessment of the skin ...
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    7. Optical coherence tomography and confocal endomicroscopy for rhinologic pathologies: a pilot study

      Optical coherence tomography and confocal endomicroscopy for rhinologic pathologies: a pilot study
      Optical coherence tomography (OCT) and confocal endomicroscopy (CEM) have a well-established potential for early diagnosis of pre-malignant and early malignant lesions of the upper aerodigestive tract mucosa. Additional applications in ENT-diagnostics might facilitate a more widespread use by making the investment into the devices more economic. Both imaging techniques might also provide valuable information in nasal pathologies. OCT images were generated with a surgical microscope (Mller-Wedel Hi-R 1000) with an ...
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    8. Corneal Responses to Eye Rubbing with Spectral Domain Optical Coherence Tomography

      Corneal Responses to Eye Rubbing with Spectral Domain Optical Coherence Tomography
      Purpose: Surprisingly, a significant reduction (18.4%) in epithelial thickness was found after 15 seconds of eye rubbing measured using Holden-Payor optical pachometer reported in the literature. Hence, we aimed at studying the effects of compressive and shearing pressure associated with eye rubbing on total corneal, epithelial and Bowman’s membrane thickness using spectral domain OCT (SD-OCT). Methods: SD-OCT (Spectralis; Heidelberg Engineering) was used to acquire cross-sectional images of the ...
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    9. An optical coherence tomography study for imaging the round window niche and the promontorium tympani

      An optical coherence tomography study for imaging the round window niche and the promontorium tympani
      Tympanosclerosis may involve the tympanic membrane, the ossicles, as well as the oval and round window niche, respectively. The surgical treatment of the obliterated oval window niche is most challenging. Beside stapesplasty, vibroplasty with coupling the floating mass transducer (FMT) onto the round window niche and into a new, so-called third window is indicated. In the latter situation, drilling a hole into the promontorium is necessary to couple the FMT ...
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    10. OCT in the field of laryngology: further perspectives

      OCT in the field of laryngology: further perspectives
      Early detection of cancerous lesions of the larynx may be the best method of improving patient quality of life and survival rates. New in-vivo technologies may be of great clinical relevance in improving the accuracy of sampling during microlaryngeal surgery. Optical coherence tomography (OCT) is an optical imaging technique that clearly identifies basement membrane violation caused by laryngeal cancer. With a microscope-based spectral domain OCT (SD-OCT) we reached in vivo ...
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    11. Detection of tympanic membrane movement using film patch with integrated strain gauge, assessed by optical coherence tomography: experimental study

      Detection of tympanic membrane movement using film patch with integrated strain gauge, assessed by optical coherence tomography: experimental study
      Objective: We report an ex vivo and in vivo experimental study of a device designed to measure tympanic membrane movement under normal and pathological conditions, assessed using optical coherence tomography. Materials and methods: We designed two types of flexible, round film patch with integrated strain gauge, to be attached to the tympanic membrane in order to measure tympanic membrane movement. Tympanic membrane attachment was assessed using optical coherence tomography. The ...
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    12. Optical coherence tomography allows for the reliable identification of laryngeal epithelial dysplasia and for precise biopsy: A clinicopathological study of 61 patients undergoing microlaryngoscopy

      Optical coherence tomography allows for the reliable identification of laryngeal epithelial dysplasia and for precise biopsy: A clinicopathological study of 61 patients undergoing microlaryngoscopy
      Objectives/Hypothesis: A newly developed microscope-based spectral-domain optical coherence tomography (SD-OCT) device and an endoscope-based time-domain OCT (TD-OCT) were used to assess the inter-rater reliability, sensitivity, specificity, and accuracy of benign and dysplastic laryngeal epithelial lesions. Study Design: Prospective study. Methods: OCT during microlaryngoscopy was done on 35 patients with an endoscope-based TD-OCT, and on 26 patients by an SD-OCT system integrated into an operating microscope. Biopsies were taken from ...
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    13. An optical coherence tomography study for imaging the round window niche and the promontorium tympani

      An optical coherence tomography study for imaging the round window niche and the promontorium tympani
      An optical coherence tomography study for imaging the round window niche and the promontorium tympani Tympanosclerosis may involve the tympanic membrane, the ossicles, and the oval and round window niche, respectively. The surgical treatment of the obliterated oval window niche is most challenging. Beside stapesplasty, vibroplasty coupling the floating mass transducer (FMT) onto the round window niche and into a new, so-called third window is indicated. In the latter situation ...
      Read Full Article
    14. Noninvasive Imaging Approaches to Evaluate the Patient With Known or Suspected Aortic Disease

      Both chronic and acute aortic conditions are challenges for primary care physicians and cardiac specialists. Longitudinal progression of chronic aortic diseases and appropriate timing of open or endovascular surgery are usually derived from serial noninvasive imaging studies. Rapid imaging is necessary as not to delay the diagnosis of a potentially life-threatening diagnosis. Given the frequency of missed cases of dissection, atypical presentation, and time-dependent morbidity and mortality, imaging is paramount ...
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  2. About Universität Rostock

    Universität Rostock

    University of Rostock (Universität Rostock) is the university of the city Rostock, in the German state of Mecklenburg-Vorpommern.

    Founded in 1419, it is the oldest and largest university in continental northern Europe and the Baltic Sea area as well as the second oldest in northern Europe after the University of St Andrews. It is the third oldest university in Germany in continuous operation.