1. Università Vita-Salute San Raffaele

    0 Comments Leave a Comment

    1-15 of 115 1 2 3 4 5 6 7 8 »
    1. Mentioned In 115 Articles

    2. Subretinal transient hyporeflectivity in age-related macular degeneration: a spectral-domain optical coherence tomography study

      Subretinal transient hyporeflectivity in age-related macular degeneration: a spectral-domain optical coherence tomography study
      Purpose: To describe and assess the prognostic significance of subretinal transient hyporeflectivity (STHR), a novel spectral-domain optical coherence tomography (SD-OCT) in age-related macular degeneration. Methods: Consecutive patients with AMD presenting STHR, defined as a small, well-defined, round subretinal, hyporeflective lesion on SD-OCT and without exudative signs were included. Clinical examination and SD-OCT (Spectralis, Heidelberg Engineering, Heidelberg, Germany) were analyzed at inclusion, as well as one month prior to inclusion and ...
      Read Full Article
    3. Double-kissing nano-crush for bifurcation PCI guided by live OCT imaging: Shedding light on stent positioning

      Double-kissing nano-crush for bifurcation PCI guided by live OCT imaging: Shedding light on stent positioning
      Percutaneous coronary intervention (PCI) of bifurcation lesions poses unique challenges and carries a high risk of adverse events on follow-up, mainly driven by repeat revascularization and stent thrombosis . Several techniques exist to tackle bifurcation lesions. Among those, double kissing (DK) crush has emerged in recent years as a safe and effective approach for complex bifurcations requiring a two-stent strategy. In its most recent iteration, the DK nano-crush, minimal (ideally less ...
      Read Full Article
    4. Retinal Optical Coherence Tomography in Neuromyelitis Optica

      Retinal Optical Coherence Tomography in Neuromyelitis Optica
      Background and objectives: To determine optic nerve and retinal damage in aquaporin-4 antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a large international cohort after previous studies have been limited by small and heterogeneous cohorts. Methods: The cross-sectional Collaborative Retrospective Study on retinal optical coherence tomography (OCT) in neuromyelitis optica collected retrospective data from 22 centers. Of 653 screened participants, we included 283 AQP4-IgG-seropositive patients with NMOSD and 72 ...
      Read Full Article
    5. Optical Coherence Tomography and Visual Evoked Potentials as Prognostic and Monitoring Tools in Progressive Multiple Sclerosis

      Optical Coherence Tomography and Visual Evoked Potentials as Prognostic and Monitoring Tools in Progressive Multiple Sclerosis
      Understanding the mechanisms underlying progression and developing new treatments for progressive multiple sclerosis (PMS) are among the major challenges in the field of central nervous system (CNS) demyelinating diseases. Over the last 10 years, also because of some technological advances, the visual pathways have emerged as a useful platform to study the processes of demyelination/remyelination and their relationship with axonal degeneration/protection. The wider availability and technological advances in ...
      Read Full Article
    6. Does real-time artificial intelligence-based visual pathology enhancement of three-dimensional optical coherence tomography scans optimise treatment decision in patients with nAMD? Rationale and design of the RAZORBILL study

      Does real-time artificial intelligence-based visual pathology enhancement of three-dimensional optical coherence tomography scans optimise treatment decision in patients with nAMD? Rationale and design of the RAZORBILL study
      Background/rationale Artificial intelligence (AI)-based clinical decision support tools, being developed across multiple fields in medicine, need to be evaluated for their impact on the treatment and outcomes of patients as well as optimisation of the clinical workflow. The RAZORBILL study will investigate the impact of advanced AI segmentation algorithms on the disease activity assessment in patients with neovascular age-related macular degeneration (nAMD) by enriching three-dimensional (3D) retinal optical ...
      Read Full Article
    7. OCT retinal angiography features in patients with rheumatoid arthritis: A pilot study

      OCT retinal angiography features in patients with rheumatoid arthritis: A pilot study
      Purpose: To evaluate the superficial (SCP) and deep retinal capillary plexus (DCP) by mean of optical coherence tomography angiography (OCTA) in treatment-nave patients affected by rheumatoid arthritis (RA). Methods: Between March 2019 and January 2020, patients with recent diagnosis of "definite RA" based on 2010 Rheumatoid Arthritis Classification Criteria were included in a Prospective, observational single center case-control study carried out at G.B. Bietti Foundation. Data were compared with ...
      Read Full Article
    8. The impact of different thresholds on optical coherence tomography angiography images binarization and quantitative metrics

      The impact of different thresholds on optical coherence tomography angiography images binarization and quantitative metrics
      Optical coherence tomography angiography (OCTA) provides several data regarding the status of retinal capillaries. This information can be further enlarged by employing quantitative metrics, such as vessel density (VD). A mandatory preliminary step of OCTA quantification is image binarization, a procedure used to highlight retinal capillaries on empty background. Although several binarization thresholds exist, no consensus is reached about the thresholding technique to be used. In this study, we tested ...
      Read Full Article
    9. The Spectrum of Central Choriocapillaris Abnormalities on Swept-Source Optical Coherence Tomography Angiography in the Fellow Eye of Unilateral Exudative Age-Related Macular Degeneration Patients: From Flow Deficits to Subclinical Non-Exudative Neovascula

      The Spectrum of Central Choriocapillaris Abnormalities on Swept-Source Optical Coherence Tomography Angiography in the Fellow Eye of Unilateral Exudative Age-Related Macular Degeneration Patients: From Flow Deficits to Subclinical Non-Exudative Neovascula
      We evaluated the spectrum of choriocapillaris (CC) abnormalities in the fellow eyes of unilateral exudative age-related macular degeneration (AMD) patients using swept-source optical coherence tomography angiography (SS-OCTA). Fellow eyes of unilateral exudative AMD patients were prospectively included between May 2018 and October 2018. Patients underwent a multimodal imaging including a SS-OCTA. Demographics and clinical findings were analyzed. The estimated prevalence of macular neovascularization (MNV) was computed. Number and size of ...
      Read Full Article
    10. Quantitative Optical Coherence Tomography Angiography Detects Retinal Perfusion Changes in Carotid Artery Stenosis

      Quantitative Optical Coherence Tomography Angiography Detects Retinal Perfusion Changes in Carotid Artery Stenosis
      Background: Carotid artery stenosis (CAS) is a multifaceted disease characterized by possible ocular involvement. Treatment with carotid endarterectomy helps to restore cerebral perfusion, which may prevent ocular and cerebral complications. The main aim was to assess retinal and choroidal vascular perfusion changes before and after endarterectomy in patients affected by CAS. Methods: The design of the study was prospective and observational, including patients affected by CAS and healthy controls. The ...
      Read Full Article
    11. Total flow intensity, active flow intensity and volume related flow intensity as new quantitative metrics in optical coherence tomography angiography

      Total flow intensity, active flow intensity and volume related flow intensity as new quantitative metrics in optical coherence tomography angiography
      Optical coherence tomography (OCT) angiography (OCTA) is a non-invasive tool for the in-vivo study of the intraretinal vascular network. It is based on the analysis of motion particles within the retina to reconstruct the paths followed by the erythrocytes, i.e. retinal capillaries. To date, qualitative and quantitative information are based on the morphological features disclosed by retinal capillaries. In the present study, we proposed new quantitative functional metrics, named ...
      Read Full Article
    12. Longitudinal Changes on Optical Coherence Tomography Angiography in Retinal Vein Occlusion

      Longitudinal Changes on Optical Coherence Tomography Angiography in Retinal Vein Occlusion
      Background: To evaluate the longitudinal changes on optical coherence tomography angiography (OCTA) in retinal vein occlusion (RVO). Methods: Retrospective study of patients with RVO treated with intravitreal anti-vascular endothelial growth factors (VEGF) for macular edema. Foveal avascular zone (FAZ) area, vessel density (VD), vessel length density (VLD), and adjusted flow index (AFI) were calculated. The unaffected eye of each participant was used as a control. Results: Twelve RVO eyes were ...
      Read Full Article
    13. Structural OCT Parameters Associated with Treatment Response and Macular Neovascularization Onset in Central Serous Chorioretinopathy

      Structural OCT Parameters Associated with Treatment Response and Macular Neovascularization Onset in Central Serous Chorioretinopathy
      Introduction: This study aimed to assess quantitative factors associated with treatment response and macular neovascularization (MNV) onset in central serous chorioretinopathy (CSC) through an artificial intelligence-based approach. Methods: The study was designed as an interventional, prospective case series with a planned follow-up of 36 months. We included only eyes demonstrating the first episode of CSC. All the patients underwent eplerenone or photodynamic therapy (PDT) treatment. Eyes developing MNV underwent anti-VEGF ...
      Read Full Article
    14. OCTA-guided navigated laser therapy for advanced macula neovascularization secondary to age related macular degeneration

      OCTA-guided navigated laser therapy for advanced macula neovascularization secondary to age related macular degeneration
      Introduction: To evaluate the effects of the Navilas system guided by optical coherence tomography angiography for advanced macular neovascularization (MNV) secondary to age-related macular degeneration (AMD). Methods: Prospective case-series including nine eyes presenting with advanced MNV with persistence of exudative signs, no longer responding to anti-VEGF therapy, best-corrected visual acuity at least of 1.3logMar. All patients were treated with Navilas guided by overlaid optical coherence tomography angiography (OCTA) images ...
      Read Full Article
    15. Using three-dimensional OCTA metrics improves repeatability on quantification of ischemia in eyes with diabetic macular edema

      Using three-dimensional OCTA metrics improves repeatability on quantification of ischemia in eyes with diabetic macular edema
      Purpose: Two-dimensional (2D) optical coherence tomography angiography (OCTA) is known to be prone to segmentation errors, especially in pathologic eyes. Therefore, our aim was to systematically compare intra-session repeatability between repeated scans for 2D and three-dimensional (3D) OCTA metrics in quantifying retinal perfusion in eyes with diabetic macular edema (DME). Methods: Diabetic patients with diabetic retinopathy (DR) and DME who had two consecutive OCTA imaging scans obtained during the same ...
      Read Full Article
    16. Quantitative OCTA parameter variations after treatment of macular neovascularization secondary to age-related macular degeneration

      Quantitative OCTA parameter variations after treatment of macular neovascularization secondary to age-related macular degeneration
      Purpose: Macular neovascularization (MNV) secondary to age-related macular degeneration (AMD) can be characterized by quantitative optical coherence tomography angiography (OCTA). The aim of the study was to assess the evolution of quantitative OCTA parameters after one-year of anti-VEGF injections. Methods: Nave AMD-related MNV eyes were prospectively recruited to analyze OCT and OCTA parameters, including MNV vessel tortuosity (VT) and reflectivity, at baseline and at the end of the follow-up. MNV ...
      Read Full Article
    17. 1-15 of 115 1 2 3 4 5 6 7 8 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Università Vita-Salute San Raffaele

    Università Vita-Salute San Raffaele

    Università Vita-Salute San Raffaele is a vibrant and acclaimed University in Milan, Italy.  Its campus, which converges with the San Raffaele Hospital site, is overseen by an 8-metre statue of San Raffaele that crowns the central dome of the University’s new and resplendent Headquarters. Inspired by Jesus’ invitation in the Gospel to “go forth, teach and heal”, Don Luigi Verzé, the founder, foresaw a natural progression from his seedling hospital to a renowned health care provider and to an international biomedical research and teaching centre. His vision duly came to fruition with the respective inaugurations of DIBIT, a substantial complex of research laboratories, in 1992, and of the Università Vita-Salute San Raffaele in 1996. The University opened with the Faculty of Psychology. Two years later, in 1998, the Faculty of Medicine was added, and the current triumvirate was completed with the creation, in 2002, of  the Faculty of Philosophy.