1. Università Vita-Salute San Raffaele

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    1. Mentioned In 90 Articles

    2. Optical Coherence Tomography Angiography Quantitative Assessment of Macular Neovascularization in Best Vitelliform Macular Dystrophy

      Optical Coherence Tomography Angiography Quantitative Assessment of Macular Neovascularization in Best Vitelliform Macular Dystrophy
      Purpose : To describe quantitative characteristics of macular neovascularization (MNV) in vitelliform macular dystrophy (VMD) patients by means of optical coherence tomography angiography (OCTA). Methods : The study design was a prospective case series. All patients underwent complete ophthalmologic assessment, optical coherence tomography, and OCTA. The quantitative OCTA parameters examined included vessel tortuosity and vessel dispersion of the MNV. The primary outcome was OCTA characterization of MNV in VMD. Secondary outcomes included ...
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    3. An anomalous foveal OCT-sign after posterior capsule rupture in cataract surgery: Complicated cataract surgery maculopathy

      An anomalous foveal OCT-sign after posterior capsule rupture in cataract surgery: Complicated cataract surgery maculopathy
      Purpose: To report a series of novel optical coherence tomography (SD-OCT) foveal abnormalities, that we called T-sign, that were noticed after a complicated cataract surgery with posterior capsule rupture and vitreous loss. Methods: Retrospective case series of persistent foveal changes that incurred after anteroposterior vitreo-foveal traction secondary to phacoemulsification in presence of posterior capsule rupture. Results: The study included three eyes of three patients that incurred in complicated cataract surgery ...
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    4. Advances in imaging of uveitis

      Advances in imaging of uveitis
      Advances in multimodal imaging have significantly contributed to the management of many uveitis diseases in recent years. The most significant developments include the use of optical coherence tomography to obtain a more accurate and reproducible assessment of ocular inflammation, the application of optical coherence tomography angiography in choroiditis and retinal vasculitis, new possibilities for studying vitritis with ultrawide field imaging, and the most recent applications of fundus autofluorescence in uveitis ...
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    5. Optical Coherence Tomography Angiography in Neurodegenerative Disorders

      Optical Coherence Tomography Angiography in Neurodegenerative Disorders
      Retinal microcirculation shares similar features with cerebral small blood vessels. Thus, the retina may be considered an accessible window to detect the microvascular damage occurring in the setting of neurodegenerative disorders. Optical coherence tomography angiography (OCT-A) is a non-invasive imaging modality providing depth resolved images of blood flow in the retina, choroid, and optic nerve. In this review, we summarize the current literature on the application of OCT-A in glaucoma ...
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    6. Macular optical coherence tomography findings after vitreoretinal surgery for rhegmatogenous retinal detachment

      Macular optical coherence tomography findings after vitreoretinal surgery for rhegmatogenous retinal detachment
      The primary aim of this study was to summarize and illustrate the main structural cross-sectional optical coherence tomography findings encountered after vitreoretinal surgery for rhegmatogenous retinal detachment. This was a non-systematic review of literature on structural cross-sectional optical coherence tomography findings after vitreoretinal surgery for rhegmatogenous retinal detachment. Adequate illustrations of the main findings described were found after a retrospective analysis of imaging and charts of patients operated at the ...
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    7. Choroidal Vascularity Index: An In-Depth Analysis of This Novel Optical Coherence Tomography Parameter

      Choroidal Vascularity Index: An In-Depth Analysis of This Novel Optical Coherence Tomography Parameter
      Remarkable improvements in optical coherence tomography (OCT) technology have resulted in highly sophisticated, noninvasive machines allowing detailed and advanced morphological evaluation of all retinal and choroidal layers. Postproduction semiautomated imaging analysis with dedicated public-domain software allows precise quantitative analysis of binarized OCT images. In this regard, the choroidal vascularity index (CVI) is emerging as a new imaging tool for the measurement and analysis of the choroidal vascular system by quantifying ...
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    8. Differences in the presentation of stage 1 macular holes illustration by optical coherence tomography

      Differences in the presentation of stage 1 macular holes illustration by optical coherence tomography
      Objective: To present two different phases of progression of Gass stage 1 foveolar detachment to lamellar or full-thickness macular holes revealed with spectral domain optical coherence tomography. Design: This is an observational study. Participants: The medical records of four patients (four eyes) with foveolar detachment that had evolved into stage 1 macular holes were compared. The patients manifested neither co-existing myopia nor any other ocular pathology. Methods: At each consultation ...
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    9. Optical Coherence Tomography Angiography in Extensive Macular Atrophy with Pseudodrusen-Like Appearance

      Optical Coherence Tomography Angiography in Extensive Macular Atrophy with Pseudodrusen-Like Appearance
      Purpose : Analyses of quantitative features of optical coherence tomography angiography (OCTA) in patients affected by extensive macular atrophy with pseudodrusen-like appearance (EMAP). Methods : In a prospective case-control study, patients and age- and gender-matched healthy controls underwent complete ophthalmologic examination, including best corrected visual acuity (BCVA) measurement, biomicroscopy, fundus autofluorescence and spectral-domain optical coherence tomography (Spectralis HRA; Heidelberg Engineering GmbH, Heidelberg, Germany), and OCTA scans (DRI OCT Triton; Topcon Corporation, Tokyo ...
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    10. Appearance of cysts and capillary non perfusion areas in diabetic macular edema using two different OCTA devices

      Appearance of cysts and capillary non perfusion areas in diabetic macular edema using two different OCTA devices
      The aim of this paper was to distinguish the appearance of cysts and non-perfusion areas (NPAs) in diabetic macular edema (DME) using two different Optical Coherence Tomography Angiography (OCTA) devices. In this study, patients underwent OCTA using the AngioVue XR Avanti Spectral Domain (SD) OCTA and the PLEX Elite 9000 Swept-Source (SS) OCTA. Foveal and extrafoveal regions of interest (ROI), defined as any area with an altered flow signal comparing ...
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    11. OCTA characterisation of microvascular retinal alterations in patients with central serous chorioretinopathy

      OCTA characterisation of microvascular retinal alterations in patients with central serous chorioretinopathy
      Purpose This study aimed to describe the characteristics of microvascular retinal alterations in eyes with chronic central serous chorioretinopathy (CSC) employing optical coherence tomography angiography (OCTA) analysis. Methods We collected data from 472 eyes with chronic CSC from 336 patients who had OCTA obtained. Each OCTA image was graded by two readers to assess the presence of microvascular retinal alterations, including regions of vascular rarefaction/retinal hypoperfusion, enlargement of the ...
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    12. Optical coherence tomography angiography in diabetes: A review

      Optical coherence tomography angiography in diabetes: A review
      Diabetic retinopathy is a common diabetes complication representing a heavy burden in terms of visual impairment and heath expenditure. Optical coherence tomography angiography is a relatively new imaging method and has proven to be a powerful tool in the analysis of diabetic retinopathy common features, including microaneurysms, intraretinal microvascular abnormalities, or neovascularization, as well as in research field, challenging the gold standard of fluorescein angiography. Many studies underlined the vascular ...
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    13. An optical coherence tomography-based grading of diabetic maculopathy proposed by an international expert panel: The European School for Advanced Studies in Ophthalmology classification

      An optical coherence tomography-based grading of diabetic maculopathy proposed by an international expert panel: The European School for Advanced Studies in Ophthalmology classification
      Aims: To present an authoritative, universal, easy-to-use morphologic classification of diabetic maculopathy based on spectral domain optical coherence tomography. Methods: The first draft of the project was developed based on previously published classifications and a literature search regarding the spectral domain optical coherence tomography quantitative and qualitative features of diabetic maculopathy. This draft was sent to an international panel of retina experts for a first revision. The panel met at ...
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    14. Widefield optical coherence tomography angiography in diabetic retinopathy

      Widefield optical coherence tomography angiography in diabetic retinopathy
      Aims To evaluate superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillaris (CC) perfusion in macular and near/mid periphery regions in diabetic patients using widefield swept-source optical coherence tomography angiography (WSS-OCTA). Methods Ninety-four diabetic patients (94 eyes) classified as diabetics without diabetic retinopathy (no DR) (25 eyes), mild DR (23 eyes), moderate/severe DR (26 eyes), proliferative DR (20 eyes) and a control group of 25 healthy subjects ...
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    15. Optical Coherence Tomography Parameters as Predictors of Treatment Response to Eplerenone in Central Serous Chorioretinopathy

      Optical Coherence Tomography Parameters as Predictors of Treatment Response to Eplerenone in Central Serous Chorioretinopathy
      Purpose : To present data on clinical response to eplerenone over a 1-year period in patients with central serous chorioretinopathy (CSC), and to evaluate optical coherence tomography (OCT) variables as predictors of treatment response at 3- and 12-month follow-up visits. Methods : Patients with acute or chronic CSC treated with eplerenone were retrospectively included. Clinical and imaging characteristics were recorded at baseline and at the 3-month and 12-month follow-up visits. Changes from ...
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    16. MULTIMODAL IMAGING AND TREATMENT OF SYPHILITIC CHOROIDAL NEOVASCULARIZATION

      MULTIMODAL IMAGING AND TREATMENT OF SYPHILITIC CHOROIDAL NEOVASCULARIZATION
      Purpose: To report a rare case of choroidal neovascularization (CNV) developed 2 years after successful treatment of ocular syphilis , identified by optical coherence tomography angiography . Methods: Case report. Results: A 31-year-old man with a history of syphilitic chorioretinitis developed a CNV 2 years after clinical remission of the infection. Structural optical coherence tomography (OCT) and optical coherence tomography angiography were helpful in providing detailed evidence of an extrafoveal CNV in ...
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  2. About Università Vita-Salute San Raffaele

    Università Vita-Salute San Raffaele

    Università Vita-Salute San Raffaele is a vibrant and acclaimed University in Milan, Italy.  Its campus, which converges with the San Raffaele Hospital site, is overseen by an 8-metre statue of San Raffaele that crowns the central dome of the University’s new and resplendent Headquarters. Inspired by Jesus’ invitation in the Gospel to “go forth, teach and heal”, Don Luigi Verzé, the founder, foresaw a natural progression from his seedling hospital to a renowned health care provider and to an international biomedical research and teaching centre. His vision duly came to fruition with the respective inaugurations of DIBIT, a substantial complex of research laboratories, in 1992, and of the Università Vita-Salute San Raffaele in 1996. The University opened with the Faculty of Psychology. Two years later, in 1998, the Faculty of Medicine was added, and the current triumvirate was completed with the creation, in 2002, of  the Faculty of Philosophy.