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    1. Mentioned In 148 Articles

    2. CORRELATION OF EN FACE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AVERAGING VERSUS SINGLE-IMAGE QUANTITATIVE MEASUREMENTS WITH RETINAL VEIN OCCLUSION VISUAL OUTCOMES

      CORRELATION OF EN FACE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AVERAGING VERSUS SINGLE-IMAGE QUANTITATIVE MEASUREMENTS WITH RETINAL VEIN OCCLUSION VISUAL OUTCOMES
      Purpose: To demonstrate the effect of averaging multiple en face optical coherence tomography angiography images on the correlation between retinal microvasculature quantitative metrics and best-corrected visual acuity (BCVA) in eyes with retinal vein occlusion . Methods: A cross-sectional cohort with unilateral retinal vein occlusion was imaged in both eyes. Five 3 mm 3-mm spectral domain optical coherence tomography angiography images were averaged, and quantitative parameters from averaged versus single images were ...
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    3. Evaluation of Corneal Epithelial Thickness Imaged by the High Definition Optical Coherence Tomography in Healthy Eyes

      Evaluation of Corneal Epithelial Thickness Imaged by the High Definition Optical Coherence Tomography in Healthy Eyes
      Purpose: To evaluate corneal epithelial thickness (CET) and corneal thickness (CT) in healthy eyes using spectral domain optical coherence tomography. Methods: Thirty-six healthy eyes were imaged using the Cirrus high-definition (HD)-optical coherence tomography device. The average CET and CT were assessed using Cirrus Review Software within predefined concentric corneal ring-shaped zones. Specific regions of CET (superior, inferior, temporal, nasal, superonasal, inferotemporal, superotemporal, and inferonasal) were also assessed. The difference ...
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    4. Comparison of anterior segment optical coherence tomography parameters among Vietnamese, Chinese, and Caucasians

      Comparison of anterior segment optical coherence tomography parameters among Vietnamese, Chinese, and Caucasians
      Purpose To evaluate the difference in anterior segment optical coherence tomography (AS-OCT) parameters among ethnic Vietnamese, Chinese, and Caucasians Design Cross-sectional study Methods We prospectively recruited phakic non-glaucomatous participants (based on intraocular pressure 21 mmHg, normal optic nerve head and retinal nerve fiber, and cup-to-disc ratio 0.6) of three ethnic groups Vietnamese, Chinese, and Caucasians. AS-OCT parameters including angle (angle opening distance, trabecular-iris space area, and angle recess area ...
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      Mentions: Shan C. Lin UCSF
    5. Aging-associated changes in cerebral vasculature and blood flow as determined by quantitative optical coherence tomography angiography

      Aging-associated changes in cerebral vasculature and blood flow as determined by quantitative optical coherence tomography angiography
      Capillary velocity increases by 21% and velocity heterogeneity increases by 19% with older age. Abstract Normal aging is associated with significant alterations in brains vascular structure and function, which can lead to compromised cerebral circulation and increased risk of neurodegeneration. The in vivo examination of cerebral blood flow (CBF), including capillary beds, in aging brains with sufficient spatial detail remains challenging with current imaging modalities. In the present study, we ...
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    6. Use of Optical Clearing Agents for Imaging Root Surfaces With Optical Coherence Tomography

      Use of Optical Clearing Agents for Imaging Root Surfaces With Optical Coherence Tomography
      The diagnosis of root caries and root fractures is of increasing importance due to our aging population. The objective of this study is to show that optical clearing agents can be used to increase the visibility of subsurface structures in tooth roots to aid in the diagnosis of root caries depth and extension and to differentiate from subsurface defects. Previous studies have shown that high refractive index fluids can increase ...
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    7. Agreement of Anterior Segment Parameters Obtained From Swept-Source Fourier-Domain and Time-Domain Anterior Segment Optical Coherence Tomography

      Agreement of Anterior Segment Parameters Obtained From Swept-Source Fourier-Domain and Time-Domain Anterior Segment Optical Coherence Tomography
      Purpose : To assess the interdevice agreement between swept-source Fourier-domain and time-domain anterior segment optical coherence tomography (AS-OCT). Methods : Fifty-three eyes from 41 subjects underwent CASIA2 and Visante OCT imaging. One hundred eightydegree axis images were measured with the built-in two-dimensional analysis software for the swept-source Fourier-domain AS-OCT (CASIA2) and a customized program for the time-domain AS-OCT (Visante OCT). In both devices, we examined the angle opening distance (AOD), trabecular iris ...
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      Mentions: Shan C. Lin UCSF
    8. Multicenter reliability of semiautomatic retinal layer segmentation using OCT

      Multicenter reliability of semiautomatic retinal layer segmentation using OCT
      Objective To evaluate the inter-rater reliability of semiautomated segmentation of spectral domain optical coherence tomography (OCT) macular volume scans. Methods Macular OCT volume scans of left eyes from 17 subjects (8 patients with MS and 9 healthy controls) were automatically segmented by Heidelberg Eye Explorer (v1.9.3.0) beta-software (Spectralis Viewing Module v6.0.0.7), followed by manual correction by 5 experienced operators from 5 different academic centers ...
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    9. Lesion dehydration rate changes with the surface layer thickness during enamel remineralization

      Lesion dehydration rate changes with the surface layer thickness during enamel remineralization
      A transparent highly mineralized outer surface zone is formed on caries lesions during remineralization that reduces the permeability to water and plaque generated acids. However, it has not been established how thick the surface zone should be to inhibit the penetration of these fluids. Near-IR (NIR) reflectance coupled with dehydration can be used to measure changes in the fluid permeability of lesions in enamel and dentin. Based on our previous ...
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    10. Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study

      Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
      Background Most patients with multiple sclerosis without previous optic neuritis have thinner retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre layer (pRNFL) thickness and macular volume in eyes with no history of optic neuritis as a biomarker of disability worsening in a cohort of patients with multiple sclerosis who had at least one eye without optic neuritis available. Methods In this multicentre, cohort study ...
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    11. CLASSIFICATION AND QUANTITATIVE ANALYSIS OF GEOGRAPHIC ATROPHY JUNCTIONAL ZONE USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

      CLASSIFICATION AND QUANTITATIVE ANALYSIS OF GEOGRAPHIC ATROPHY JUNCTIONAL ZONE USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
      Purpose: The junctional zone at the border of areas of geographic atrophy (GA) in eyes with nonneovascular age-related macular degeneration is an important target region for future therapeutic strategies. The goal of this study was to perform a detailed classification and quantitative characterization of the junctional zone using spectral domain optical coherence tomography. Methods: Spectral domain optical coherence tomography volume cube scans (Spectralis OCT, 1024 x 37, Automatic Real Time ...
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    12. Comparison of macular choroidal thickness in patients with pseudoexfoliation syndrome to normal control subjects with enhanced-depth SD-OCT imaging

      Comparison of macular choroidal thickness in patients with pseudoexfoliation syndrome to normal control subjects with enhanced-depth SD-OCT imaging
      Purpose To test the hypothesis that macular choroidal thickness is lower in patients with pseudoexfoliation syndrome (PXS) as compared to healthy control subjects. Methods In this cross-sectional, observational study, 38 non-glaucomatous PXS subjects and 37 healthy volunteers were enrolled in a tertiary care Glaucoma Clinic. The macular region was scanned with the enhanced depth imaging (EDI) protocol of a spectral domain optical coherence tomography (SD-OCT) device (Spectralis OCT, Heidelberg Engineering ...
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    13. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system

      Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system
      Objective The purpose of this study is to assemble a laser system for the selective removal of dental composite from tooth surfaces, that is feasible for clinical use incorporating a spectral feedback system, a scanning system, articulating arm and a clinical hand-piece, and evaluate the performance of that system on extracted teeth. Methods Ten extracted teeth were collected and small fillings were placed on the occlusal surface of each tooth ...
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    14. Scientists look FTD in the eye

      Scientists look FTD in the eye
      A routine eye test may help clinicians identify early signs of at least one form of FTD according to a new study published on April 12 in Science Translational Medicine. The study, led by Li Gan and Ari Green at the University of California in San Francisco, found that people heterozygous for progranulin (GRN) mutations without cognitive symptoms exhibited twice the number of lipid-rich deposits, known as lipofuscin, in the ...
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      Mentions: UCSF
    15. Effects of diurnal, lighting, and angle-of-incidence variation on anterior segment optical coherence tomography (AS-OCT) angle metrics

      Effects of diurnal, lighting, and angle-of-incidence variation on anterior segment optical coherence tomography (AS-OCT) angle metrics
      Background First reported study to assess the effect of diurnal variation on anterior chamber angle measurements, as well as, to re-test the effects of lighting and angle-of-incidence variation on anterior chamber angle (ACA) measurements acquired by time-domain anterior segment optical coherence tomography (AS-OCT). Methods A total of 30 eyes from 15 healthy, normal subjects underwent anterior chamber imaging using a Visante time-domain AS-OCT according to an IRB-approved protocol. For each ...
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  2. About UCSF

    UCSF

    University of California at San Francisco (UCSF) is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dental, nursing, and graduate schools are among the top health science professional schools in the world. The UCSF Medical Center is consistently ranked among the top 10 hospitals in the United States by U.S. News & World Report. Some of UCSF's most renowned treatment centers include kidney and liver transplant, neurosurgery, neurology, oncology, ophthalmology, gene therapy, women's health, fetal surgery, pediatrics, and internal medicine. UCSF also has the nation's leading HIV/AIDS treatment and research centers. Collaborations with African Universities such as the University of Zimbabwe to deal with HIV have been established. UCSF should not be confused with the Hastings College of the Law, a separate institution of the University of California which is also located in San Francisco.