1. UCSF

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    1. Mentioned In 142 Articles

    2. Agreement of Anterior Segment Parameters Obtained From Swept-Source Fourier-Domain and Time-Domain Anterior Segment Optical Coherence Tomography

      Agreement of Anterior Segment Parameters Obtained From Swept-Source Fourier-Domain and Time-Domain Anterior Segment Optical Coherence Tomography
      Purpose : To assess the interdevice agreement between swept-source Fourier-domain and time-domain anterior segment optical coherence tomography (AS-OCT). Methods : Fifty-three eyes from 41 subjects underwent CASIA2 and Visante OCT imaging. One hundred eightydegree axis images were measured with the built-in two-dimensional analysis software for the swept-source Fourier-domain AS-OCT (CASIA2) and a customized program for the time-domain AS-OCT (Visante OCT). In both devices, we examined the angle opening distance (AOD), trabecular iris ...
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      Mentions: Shan C. Lin UCSF
    3. Multicenter reliability of semiautomatic retinal layer segmentation using OCT

      Multicenter reliability of semiautomatic retinal layer segmentation using OCT
      Objective To evaluate the inter-rater reliability of semiautomated segmentation of spectral domain optical coherence tomography (OCT) macular volume scans. Methods Macular OCT volume scans of left eyes from 17 subjects (8 patients with MS and 9 healthy controls) were automatically segmented by Heidelberg Eye Explorer (v1.9.3.0) beta-software (Spectralis Viewing Module v6.0.0.7), followed by manual correction by 5 experienced operators from 5 different academic centers ...
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    4. Lesion dehydration rate changes with the surface layer thickness during enamel remineralization

      Lesion dehydration rate changes with the surface layer thickness during enamel remineralization
      A transparent highly mineralized outer surface zone is formed on caries lesions during remineralization that reduces the permeability to water and plaque generated acids. However, it has not been established how thick the surface zone should be to inhibit the penetration of these fluids. Near-IR (NIR) reflectance coupled with dehydration can be used to measure changes in the fluid permeability of lesions in enamel and dentin. Based on our previous ...
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    5. Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study

      Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
      Background Most patients with multiple sclerosis without previous optic neuritis have thinner retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre layer (pRNFL) thickness and macular volume in eyes with no history of optic neuritis as a biomarker of disability worsening in a cohort of patients with multiple sclerosis who had at least one eye without optic neuritis available. Methods In this multicentre, cohort study ...
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    6. CLASSIFICATION AND QUANTITATIVE ANALYSIS OF GEOGRAPHIC ATROPHY JUNCTIONAL ZONE USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

      CLASSIFICATION AND QUANTITATIVE ANALYSIS OF GEOGRAPHIC ATROPHY JUNCTIONAL ZONE USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
      Purpose: The junctional zone at the border of areas of geographic atrophy (GA) in eyes with nonneovascular age-related macular degeneration is an important target region for future therapeutic strategies. The goal of this study was to perform a detailed classification and quantitative characterization of the junctional zone using spectral domain optical coherence tomography. Methods: Spectral domain optical coherence tomography volume cube scans (Spectralis OCT, 1024 x 37, Automatic Real Time ...
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    7. Comparison of macular choroidal thickness in patients with pseudoexfoliation syndrome to normal control subjects with enhanced-depth SD-OCT imaging

      Comparison of macular choroidal thickness in patients with pseudoexfoliation syndrome to normal control subjects with enhanced-depth SD-OCT imaging
      Purpose To test the hypothesis that macular choroidal thickness is lower in patients with pseudoexfoliation syndrome (PXS) as compared to healthy control subjects. Methods In this cross-sectional, observational study, 38 non-glaucomatous PXS subjects and 37 healthy volunteers were enrolled in a tertiary care Glaucoma Clinic. The macular region was scanned with the enhanced depth imaging (EDI) protocol of a spectral domain optical coherence tomography (SD-OCT) device (Spectralis OCT, Heidelberg Engineering ...
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    8. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system

      Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system
      Objective The purpose of this study is to assemble a laser system for the selective removal of dental composite from tooth surfaces, that is feasible for clinical use incorporating a spectral feedback system, a scanning system, articulating arm and a clinical hand-piece, and evaluate the performance of that system on extracted teeth. Methods Ten extracted teeth were collected and small fillings were placed on the occlusal surface of each tooth ...
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    9. Scientists look FTD in the eye

      Scientists look FTD in the eye
      A routine eye test may help clinicians identify early signs of at least one form of FTD according to a new study published on April 12 in Science Translational Medicine. The study, led by Li Gan and Ari Green at the University of California in San Francisco, found that people heterozygous for progranulin (GRN) mutations without cognitive symptoms exhibited twice the number of lipid-rich deposits, known as lipofuscin, in the ...
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      Mentions: UCSF
    10. Effects of diurnal, lighting, and angle-of-incidence variation on anterior segment optical coherence tomography (AS-OCT) angle metrics

      Effects of diurnal, lighting, and angle-of-incidence variation on anterior segment optical coherence tomography (AS-OCT) angle metrics
      Background First reported study to assess the effect of diurnal variation on anterior chamber angle measurements, as well as, to re-test the effects of lighting and angle-of-incidence variation on anterior chamber angle (ACA) measurements acquired by time-domain anterior segment optical coherence tomography (AS-OCT). Methods A total of 30 eyes from 15 healthy, normal subjects underwent anterior chamber imaging using a Visante time-domain AS-OCT according to an IRB-approved protocol. For each ...
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    11. Near-IR and CP-OCT imaging of suspected occlusal caries lesions

      Near-IR and CP-OCT imaging of suspected occlusal caries lesions
      Introduction Radiographic methods have poor sensitivity for occlusal lesions and by the time the lesions are radiolucent they have typically progressed deep into the dentin. New more sensitive imaging methods are needed to detect occlusal lesions. In this study, cross-polarization optical coherence tomography (CP-OCT) and near-IR imaging were used to image questionable occlusal lesions (QOC's) that were not visible on radiographs but had been scheduled for restoration on 30 ...
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    12. Distinguishing between contact lens warpage and ectasia: Usefulness of optical coherence tomography epithelial thickness mapping

      Distinguishing between contact lens warpage and ectasia: Usefulness of optical coherence tomography epithelial thickness mapping
      Purpose To distinguish between corneal ectasia and contact lensrelated warpage by characteristic patterns on corneal topography and optical coherence tomography (OCT) epithelial thickness maps. Setting Casey Eye Institute, Portland, Oregon, USA. Design Prospective and retrospective case series. Methods Axial and mean power maps were obtained on corneal topography systems. Epithelial thickness maps were generated using RTVue OCT. A sector divider was applied to all maps. The locations of the minimum ...
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    13. Impact of Multiple En Face Image Averaging on Quantitative Assessment from Optical Coherence Tomography Angiography Images

      Impact of Multiple En Face Image Averaging on Quantitative Assessment from Optical Coherence Tomography Angiography Images
      Purpose To investigate the impact of multiple en face image averaging on quantitative measurements of the retinal microvasculature using optical coherence tomography angiography (OCTA). Design Prospective, observational, cross-sectional case series. Participants Twenty-one healthy individuals with normal eyes. Methods Macular OCTA images were acquired from all participants using the Zeiss Cirrus 5000 with Angioplex OCTA software (Carl Zeiss Meditec, Dublin, CA). Nine OCTA cube scans per eye were obtained and 9 ...
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    14. Comparison of Anterior Chamber Parameters in Patients With Plateau Iris Configuration and Pupillary Block Using ASOCT

      Comparison of Anterior Chamber Parameters in Patients With Plateau Iris Configuration and Pupillary Block Using ASOCT
      Purpose: To quantitatively analyze the anterior chamber parameters in patients with pupillary block (PB) and plateau iris configuration (PIC) using anterior segment optical coherence tomography (ASOCT). Patients and Methods: In this cross-sectional study, nonglaucomatous subjects consecutively recruited and a total of 212 eyes divided into 3 groups of PIC (31 eyes), PB (60 eyes), and open angles (121 eyes) based on gonioscopic and ultrasound biomicroscopy findings. All patients underwent ASOCT ...
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    15. Optical Coherence Tomography Angiography Analysis of the Foveal Avascular Zone and Macular Vessel Density After Anti-VEGF Therapy in Eyes With Diabetic Macular Edema and Retinal Vein Occlusion

      Optical Coherence Tomography Angiography Analysis of the Foveal Avascular Zone and Macular Vessel Density After Anti-VEGF Therapy in Eyes With Diabetic Macular Edema and Retinal Vein Occlusion
      Purpose : To evaluate the changes in foveal avascular zone (FAZ) area and the retinal capillary density after a single intravitreal anti-VEGF injection for macular edema secondary to diabetic retinopathy or retinal vein occlusion. Methods : In this prospective noncomparative case series, 18 eyes of 15 patients with diabetic macular edema (13 eyes) or macular edema secondary to central retinal vein occlusion (5 eyes) were included. Optical coherence tomography angiography (OCTA) images ...
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  2. About UCSF

    UCSF

    University of California at San Francisco (UCSF) is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dental, nursing, and graduate schools are among the top health science professional schools in the world. The UCSF Medical Center is consistently ranked among the top 10 hospitals in the United States by U.S. News & World Report. Some of UCSF's most renowned treatment centers include kidney and liver transplant, neurosurgery, neurology, oncology, ophthalmology, gene therapy, women's health, fetal surgery, pediatrics, and internal medicine. UCSF also has the nation's leading HIV/AIDS treatment and research centers. Collaborations with African Universities such as the University of Zimbabwe to deal with HIV have been established. UCSF should not be confused with the Hastings College of the Law, a separate institution of the University of California which is also located in San Francisco.