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    1. Mentioned In 179 Articles

    2. Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation with Disease Severity

      Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation with Disease Severity
      Purpose: To investigate baseline mesopic microperimetry (MP) and spectral domain optical coherence tomography (OCT) in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) study. Design: Natural history study SETTING: 16 clinical sites in Europe and North America STUDY POPULATION: Participants with Usher syndrome type 2 (USH2) (N=80) or autosomal recessive nonsyndromic RP (ARRP) (N=47) associated with biallelic disease-causing sequence variants in USH2A. Observation procedures: General linear models ...
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    3. Persistent subfoveal fluid in pneumatic retinopexy versus pars plana vitrectomy for rhegmatogenous retinal detachment: posthoc analysis of the PIVOT randomised trial

      Persistent subfoveal fluid in pneumatic retinopexy versus pars plana vitrectomy for rhegmatogenous retinal detachment: posthoc analysis of the PIVOT randomised trial
      Purpose To assess the incidence of persistent subfoveal fluid (PSFF) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) following rhegmatogenous retinal detachment (RRD) repair and to determine its association with functional outcomes. Methods Posthoc analysis of the PIVOT randomised trial. Eyes with gradable en face and cross-sectional spectral-domain optical coherence tomography (SD-OCT) scans at 12 months postoperatively were included. Primary outcome was the proportion of patients with PSFF following ...
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    4. Relationship Between Optical Coherence Tomography and Anterior Chamber Depth after Pupillary Dilation in Primary Angle Closure Suspects

      Relationship Between Optical Coherence Tomography and Anterior Chamber Depth after Pupillary Dilation in Primary Angle Closure Suspects
      Precis: Anterior chamber depth change after pupillary dilation is correlated with lens vault and anterior chamber width, as observed by SS-OCT at both horizontal and vertical scans in patients with PACS and cataract. Purpose: To evaluate the association between anterior chamber depth (ACD) and other anterior chamber parameters after pharmacological dilation in patients with primary angle closure suspect (PACS) and cataract. Patients and Methods: Swept-source optical coherence tomography (SS-OCT) was ...
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    5. Preservation of choriocapillaris perfusion on optical coherence tomography angiography in an eye treated with macular buckle

      Preservation of choriocapillaris perfusion on optical coherence tomography angiography in an eye treated with macular buckle
      A 64-year-old female who had undergone successful pars plana vitrectomy (PPV), epiretinal and internal limiting membrane peel and gas for myopic foveoschisis and full thickness macular hole (FTMH) presented with recurrent FTMH with new total retinal detachment and no peripheral break ( Fig. 1 A and B) and visual acuity of hand motions. A decision was made to proceed with repeat PPV with gas and macular buckle placement. The macular buckle ...
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      Mentions: UCSF
    6. A Global and Sector-Based Comparison of OCT Angiography and Visual Field Defects in Glaucoma

      A Global and Sector-Based Comparison of OCT Angiography and Visual Field Defects in Glaucoma
      Purpose: To evaluate the correlation of optical coherence tomography angiography (OCTA) and spectral-domain optical coherence tomography (SD-OCT) with visual field for global and sector-based indices among glaucoma and glaucoma-suspected eyes. Patients and Methods . This is a retrospective study, and in total, 48 glaucoma eyes and 31 glaucoma suspect eyes were included. The correlation between visual field parameters and radial peripapillary capillary (RPC) vessel density via OCTA was compared to the ...
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      Mentions: UCSF
    7. Choroidal Thickness in Multiple Sclerosis: An Optical Coherence Tomography Study

      Choroidal Thickness in Multiple Sclerosis: An Optical Coherence Tomography Study
      Background and Purpose To identify changes in the choroidal thickness (CT) in multiple sclerosis (MS) patients with and without optic neuritis (ON) using enhanced-depth-imaging optical coherence tomography (EDI-OCT). Methods This cross-sectional study included 96 eyes with MS and 28 eyes of healthy controls. All participants underwent an ophthalmologic examination and EDI-OCT scanning (Spectralis, Heidelberg Engineering, Germany) to assess the CT and the retinal nerve fiber layer (RNFL) thickness. MS patients ...
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      Mentions: UCSF
    8. Monitoring silver diamine fluoride application with optical coherence tomography and thermal imaging: An in vitro proof of concept study

      Monitoring silver diamine fluoride application with optical coherence tomography and thermal imaging: An in vitro proof of concept study
      Objectives: The purpose of this study was to show that optical coherence tomography (OCT) and thermal imaging can be used to monitor changes in the structure and activity of caries lesions over time after treatment with silver diamine fluoride (SDF). Methods: Artificial caries lesions were formed on enamel and dentin bovine blocks. Each block was partitioned into five windows with the central three windows exposed to a demineralization solution to ...
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      Mentions: UCSF
    9. Validation of a deep learning-based algorithm for segmentation of the ellipsoid zone on optical coherence tomography images of an USH2A-related retinal degeneration clinical trial

      Validation of a deep learning-based algorithm for segmentation of the ellipsoid zone on optical coherence tomography images of an USH2A-related retinal degeneration clinical trial
      Purpose: To assess the generalizability of a deep learning-based algorithm to segment the ellipsoid zone (EZ). Methods: The dataset consisted of 127 spectral-domain optical coherence tomography volumes from eyes of participants with USH2A-related retinal degeneration enrolled in the RUSH2A clinical trial ( NCT03146078 ). The EZ was segmented manually by trained Readers and automatically by DOCTAD, a deep learning-based algorithm originally developed for macular telangiectasia type 2. Performance was evaluated using the ...
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    10. Diagnostic Performance of Deep Learning Classifiers in Measuring Peripheral Anterior Synechia Based on Swept Source Optical Coherence Tomography Images

      Diagnostic Performance of Deep Learning Classifiers in Measuring Peripheral Anterior Synechia Based on Swept Source Optical Coherence Tomography Images
      Purpose: To develop deep learning classifiers and evaluate their diagnostic performance in detecting the static gonioscopic angle closure and peripheral anterior synechia (PAS) based on swept source optical coherence tomography (SS-OCT) images. Materials and methods: Subjects were recruited from the Glaucoma Service at Zhongshan Ophthalmic Center of Sun Yat-sun University, Guangzhou, China. Each subject underwent a complete ocular examination, such as gonioscopy and SS-OCT imaging. Two deep learning classifiers, using ...
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    11. Quantification metrics for telangiectasia using optical coherence tomography

      Quantification metrics for telangiectasia using optical coherence tomography
      Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder that causes vascular malformations throughout the body. The most prevalent and accessible of these lesions are found throughout the skin and mucosa, and often rupture causing bleeding and anemia. A recent increase in potential HHT treatments have created a demand for quantitative metrics that can objectively measure the efficacy of new and developing treatments. We employ optical coherence tomography (OCT)-a ...
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    12. Virtual Reality Oculokinetic Perimetry Test Reproducibility and Relationship to Conventional Perimetry and OCT

      Virtual Reality Oculokinetic Perimetry Test Reproducibility and Relationship to Conventional Perimetry and OCT
      Purpose Vivid Vision Perimetry (VVP; Vivid Vision, Inc) is a novel method for performing in-office and home-based visual field assessment using a virtual reality platform and oculokinetic perimetry. Here we examine the reproducibility of VVP Swift and compare results with conventional standard automated perimetry (SAP) and spectral-domain (SD) OCT. Design Cross-sectional study. Participants Fourteen eyes of 7 patients with open-angle glaucoma (OAG) (average age, 64.6 years; 29% women) and ...
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    13. Racial and ethnic differences in foveal avascular zone in diabetic and nondiabetic eyes revealed by optical coherence tomography angiography

      Racial and ethnic differences in foveal avascular zone in diabetic and nondiabetic eyes revealed by optical coherence tomography angiography
      ...ed by the Human Research Protection Program (HRPP) at the University of California, San Francisco (UCSF). The UCSF HRPP granted a waiver of consent, affirming that patient welfare would not be adversely affected by waivi...
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    14. Retinal Optical Coherence Tomography in Neuromyelitis Optica

      Retinal Optical Coherence Tomography in Neuromyelitis Optica
      Background and objectives: To determine optic nerve and retinal damage in aquaporin-4 antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a large international cohort after previous studies have been limited by small and heterogeneous cohorts. Methods: The cross-sectional Collaborative Retrospective Study on retinal optical coherence tomography (OCT) in neuromyelitis optica collected retrospective data from 22 centers. Of 653 screened participants, we included 283 AQP4-IgG-seropositive patients with NMOSD and 72 ...
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    15. Evaluation of the diagnostic performance of swept-source anterior segment optical coherence tomography in primary angle closure disease

      Evaluation of the diagnostic performance of swept-source anterior segment optical coherence tomography in primary angle closure disease
      Purpose To evaluate the diagnostic performance of swept-source anterior segment optical coherence tomography (SS-OCT) in differentiating primary angle closure diseases (PACD) from control eyes, as well as primary angle closure (PAC) and primary angle closure glaucoma (PACG) from primary angle closure suspect (PACS) eyes. Design Multi-center cross-sectional study. Methods Chinese patients were classified into control, PACS and PAC/PACG groups. Area under the receiving operating characteristics curve (AUC) from logistic ...
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    16. Repeatability and Reproducibility of Anterior Chamber Angle Measurement with Swept-Source Optical Coherence Tomography in Patients with Primary Angle Closure Suspect

      Repeatability and Reproducibility of Anterior Chamber Angle Measurement with Swept-Source Optical Coherence Tomography in Patients with Primary Angle Closure Suspect
      Purpose : To evaluate the inter- and intra-observer reliability of anterior chamber (AC) angle measurements obtained by swept-source optical coherence tomography (SS-OCT). Methods: Forty-eight consecutive patients diagnosed with primary angle closure suspect (PACS) were included. Three masked observers at different training levels (one glaucoma specialist, one ophthalmology resident, and one pre-medical college student) measured 192 SS-OCT images of the PACS patients. One observer (the glaucoma specialist) repeated measurements 1 week later ...
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  2. About UCSF

    UCSF

    University of California at San Francisco (UCSF) is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dental, nursing, and graduate schools are among the top health science professional schools in the world. The UCSF Medical Center is consistently ranked among the top 10 hospitals in the United States by U.S. News & World Report. Some of UCSF's most renowned treatment centers include kidney and liver transplant, neurosurgery, neurology, oncology, ophthalmology, gene therapy, women's health, fetal surgery, pediatrics, and internal medicine. UCSF also has the nation's leading HIV/AIDS treatment and research centers. Collaborations with African Universities such as the University of Zimbabwe to deal with HIV have been established. UCSF should not be confused with the Hastings College of the Law, a separate institution of the University of California which is also located in San Francisco.