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    1. Mentioned In 226 Articles

    2. Central macular OCTA parameters in glaucoma

      Central macular OCTA parameters in glaucoma
      Background/aims: To investigate the relationship between the foveal avascular zone (FAZ) parameters assessed by optical coherence tomography angiography (OCTA) and central visual field parameters in glaucoma and healthy subjects. Methods: One hundred and eighty-eight subjects (248 eyes), including 24 healthy (38 eyes), 37 glaucoma suspect (42 eyes, and 127 primary open angle glaucoma (POAG) patients (168 eyes), underwent imaging using OCTA and standard automated perimetry using the 24-2 and ...
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      Mentions: UCSD
    3. Macular Optical Coherence Tomography Imaging in Glaucoma

      Macular Optical Coherence Tomography Imaging in Glaucoma
      The advent of spectral-domain optical coherence tomography has played a transformative role in posterior segment imaging of the eye. Traditionally, images of the optic nerve head and the peripapillary area have been used to evaluate the structural changes associated with glaucoma. Recently, there is growing evidence in the literature supporting the use of macular spectral-domain optical coherence tomography as a complementary tool for clinical evaluation and research purposes in glaucoma.
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      Mentions: UCSD
    4. Strain by virtual extensometers and video-imaging optical coherence tomography as a repeatable metric for IOP-Induced optic nerve head deformations

      Strain by virtual extensometers and video-imaging optical coherence tomography as a repeatable metric for IOP-Induced optic nerve head deformations
      Purpose: To determine if in vivo strain response of the Optic Nerve Head (ONH) to IOP elevation visualized using Optical Coherence Tomography (OCT) video imaging and quantified using novel virtual extensometers was able to be provided repeatable measurements of tissue specific deformations. Methods: The ONHs of 5 eyes from 5 non-human primates (NHPs) were imaged by Spectralis OCT. A vertical and a horizontal B-scan of the ONH were continuously recorded ...
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    5. Individualized Glaucoma Change Detection Using Deep Learning Auto Encoder-Based Regions of Interest

      Individualized Glaucoma Change Detection Using Deep Learning Auto Encoder-Based Regions of Interest
      Purpose : To compare change over time in eye-specific optical coherence tomography (OCT) retinal nerve fiber layer (RNFL)-based region-of-interest (ROI) maps developed using unsupervised deep-learning auto-encoders (DL-AE) to circumpapillary RNFL (cpRNFL) thickness for the detection of glaucomatous progression. Methods : Forty-four progressing glaucoma eyes (by stereophotograph assessment), 189 nonprogressing glaucoma eyes (by stereophotograph assessment), and 109 healthy eyes were followed for 3 years with 4 visits using OCT. The San Diego ...
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    6. Optical microangiography and progressive retinal nerve fiber layer loss in primary open angle glaucoma

      Optical microangiography and progressive retinal nerve fiber layer loss in primary open angle glaucoma
      Purpose : To evaluate the association between optical microangiography (OMAG) measurements and progressive retinal nerve fiber layer (RNFL) loss in primary open angle glaucoma (POAG). Design : Prospective case series Methods : Sixty-four eyes of 40 POAG patients (108 quadrants) with mild to moderate functional damage were longitudinally studied for at least 2 years and with a minimum of 3 optical coherence tomography (OCT) examinations. OMAG imaging was performed at the baseline visit ...
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    7. Long-Term Reproducibility of Optical Coherence Tomography Angiography in Stable Glaucomatous Eyes

      Long-Term Reproducibility of Optical Coherence Tomography Angiography in Stable Glaucomatous Eyes
      Purpose : To assess and compare long-term reproducibility of optical coherence tomography angiography (OCTA) vascular parameters and spectral-domain optical coherence tomography (OCT) thickness parameters in stable glaucoma, glaucoma suspect, and healthy eyes. Methods : A total of 88 eyes (15 healthy, 38 glaucoma suspect, and 35 non-progressive POAG) of 68 subjects were enrolled who had at least 3 visits within 1 to 1.5 years and both OCT and OCTA (Optovue Inc ...
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    8. Predicting central 10 degrees visual field from peripapillary optical coherence tomography using deep learning approach

      Predicting central 10 degrees visual field from peripapillary optical coherence tomography using deep learning approach
      Purpose: To develop a deep learning (DL) simulation of standard automated perimetry (SAP) in the central 10 based on spectral domain optical coherence tomography (SD-OCT) retinal nerve fiber layer thickness (RNFLT). Methods : This study included 5352 pairs of SD-OCT and 10-2 SAP from 1365 eyes of 724 healthy, glaucoma suspect and glaucoma patients from the Diagnostic Innovations in Glaucoma Study (DIGS) and the African Descent and Glaucoma Evaluation Study (ADAGES ...
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    9. UCSD Receives NIH Grant for Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography

      UCSD Receives NIH Grant for Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography
      University of California, San Diego Receives a 2021 NIH Grant for $489,850 for Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography. The principal investigator is Robert Weinreb Below is a summary of the proposed work. Project Summary Optical coherence tomography angiography (OCTA) has been introduced recently as a non- invasive, 3-dimensional imaging method to visualize and quantify microvasculature throughout the retina. The proposed study evaluates the clinical ...
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    10. The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies

      The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies
      Objective: To update the consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results, thus revising the previously published Advised Protocol for OCT Study Terminology and Elements (APOSTEL) recommendations. Methods: To identify studies reporting quantitative OCT results, we performed a PubMed search for the terms "quantitative" and "optical coherence tomography" from 2015 to 2017. Corresponding authors of the identified publications were invited to provide feedback on the initial ...
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    11. Optical Coherence Tomography Angiography Artifacts in Glaucoma

      Optical Coherence Tomography Angiography Artifacts in Glaucoma
      Purpose: To determine the prevalence of different types of artifacts seen in optical coherence tomography angiography (OCTA) images of healthy and glaucoma eyes and to evaluate the characteristics associated with the increased likelihood of obtaining poor quality images. Design: Retrospective study. Participants: A total of 649 eyes of 368 healthy, glaucoma suspect, and glaucoma patients. Methods: Angiovue high density (HD) and non-HD optic nerve head and macula OCTA images of ...
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    12. Prevalence of subclinical retinal ischemia in patients with cardiovascular disease – a hypothesis driven study

      Prevalence of subclinical retinal ischemia in patients with cardiovascular disease – a hypothesis driven study
      Background Cardiovascular disease is the leading cause of mortality and disability worldwide. A noninvasive test that can detect underlying cardiovascular disease has the potential to identify patients at risk prior to the occurrence of adverse cardiovascular events. We sought to determine whether an easily observed imaging finding indicative of retinal ischemia, which we term retinal ischemic perivascular lesions (RIPLs), could serve as a biomarker for cardiovascular disease. Methods We reviewed ...
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    13. Heart Disease is in the Eye of the Beholder

      Heart Disease is in the Eye of the Beholder
      In a new study from Shiley Eye Institute at UC San Diego Health, researchers have identified a potential new marker that shows cardiovascular disease may be present in a patient using an optical coherence tomography (OCT) scan a non-invasive diagnostic tool commonly used in ophthalmology and optometry clinics to create images of the retina. The finding suggests it may be possible to detect heart disease during an eye examination. In ...
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    14. Spectral-Domain Optical Coherence Tomography For Evaluating Palisades of Vogt in Ocular Surface Disorders With Limbal Involvement

      Spectral-Domain Optical Coherence Tomography For Evaluating Palisades of Vogt in Ocular Surface Disorders With Limbal Involvement
      Spectral-domain optical coherence tomography (SD-OCT) has been used to observe the morphology and epithelial thickness of the palisades of Vogt (POV) with satisfactory resolutions. In this study, we used SD-OCT to examine the microstructure of the POV in ocular surface disorders with limbal involvement and to detect subclinical limbal pathologies based on five parameters. Eighteen eyes of 10 patients (2 men and 8 women; mean age, 48.7 14.0 ...
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  2. About UCSD

    UCSD

    University of California at San Diego (UCSD) is a public research university in San Diego, California. UCSD is one of ten University of California campuses and was founded in 1955 around the pre-existing Scripps Institution of Oceanography.  UCSD Shiley Eye Center is part of the University of California at San Diego. Shiley Eye Center physicians, all of whom are faculty members of the UCSD School of Medicine.  Also see Hamilton Glaucoma Center.