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    1. Mentioned In 149 Articles

    2. Automated circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography

      Explore SPIE | Journal Ophthalmology
      Automated circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography
      The purpose was to create a three-dimensional (3-D) model of circumferential aqueous humor outflow (AHO) in a living human eye with an automated detection algorithm for Schlemms canal (SC) and first-order collector channels (CC) applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired circumferentially around the limbus. A Bayesian Ridge method was used to approximate the location of the SC on infrared confocal ...
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      Mentions: UCSD Robert N. Weinreb UCLA

    3. Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes

      Explore LWW Online Ophthalmology
      Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes
      PURPOSE The aim of this study was to evaluate the effect of subject-related (age, sex, and systemic hypertension and diabetes), eye-related (refractive error, optic disc size), and technology-related (signal strength index, SSI of the scans) determinants on the peripapillary and macular vessel densities measured with optical coherence tomography angiography (OCTA) in normal eyes. METHODS In a cross-sectional study, 181 normal eyes of 107 subjects (45 men, 62 women, median age ...
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      Mentions: UCSD Robert N. Weinreb Academic Hospital Maastricht

    4. Measurements of the parapapillary atrophy zones in en face optical coherence tomography images

      Explore Journals | PLOS Ophthalmology
      Measurements of the parapapillary atrophy zones in en face optical coherence tomography images
      Objective To measure the parapapillary atrophy (PPA) area in en face images obtained with swept-source optical coherence tomography (SS-OCT), and to evaluate its relationship to glaucoma, myopia, and age in non-highly myopic subjects. Design Retrospective, cross-sectional study. Participants Fifty eyes of 30 subjects with open-angle glaucoma (G group) and forty-three eyes of 26 healthy control subjects (C group). Eyes with high myopia (spherical equivalent refractive error -8 diopters or axial ...
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      Mentions: UCSD Yasushi Ikuno Robert N. Weinreb

    5. Relationship of Optic Nerve Structure and Function to Peripapillary Vessel Density Measurements of Optical Coherence Tomography Angiography in Glaucoma

      Explore LWW Online Ophthalmology
      Relationship of Optic Nerve Structure and Function to Peripapillary Vessel Density Measurements of Optical Coherence Tomography Angiography in Glaucoma
      Purpose: To evaluate the sectoral and global structure-structure (vessel density-retinal nerve fiber layer thickness) and structure-function (vessel density-visual sensitivity loss) relationships of peripapillary vessel density measurements on optical coherence tomography angiography in primary open-angle glaucoma and to determine if fractional polynomial (FP) models characterize the relationships better than linear models. Materials and Methods: In a cross-sectional study, structure-structure and structure-function relationships of peripapillary vessel densities were determined in 227 eyes ...
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      Mentions: UCSD Robert N. Weinreb Academic Hospital Maastricht

    6. A comparison of the diagnostic ability of vessel density and structural measurements of optical coherence tomography in primary open angle glaucoma

      Explore Journals | PLOS Ophthalmology
      A comparison of the diagnostic ability of vessel density and structural measurements of optical coherence tomography in primary open angle glaucoma
      Purpose To compare the diagnostic abilities of vessel density measurements of the optic nerve head (ONH), peripapillary and macular regions on optical coherence tomography (OCT) angiography in eyes with primary open angle glaucoma (POAG) with that of the ONH rim area, peripapillary retinal nerve fiber layer (RNFL) thickness and the macular ganglion cell complex (GCC) thickness measurements. Methods In a cross sectional study, 78 eyes of 50 control subjects and ...
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      Mentions: Optovue Heidelberg Engineering Topcon Medical Systems

    7. Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes

      Explore insights.ovid.com Ophthalmology
      Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes
      PURPOSE The aim of this study was to evaluate the effect of subject-related (age, sex, and systemic hypertension and diabetes), eye-related (refractive error, optic disc size), and technology-related (signal strength index, SSI of the scans) determinants on the peripapillary and macular vessel densities measured with optical coherence tomography angiography (OCTA) in normal eyes. METHODS In a cross-sectional study, 181 normal eyes of 107 subjects (45 men, 62 women, median age ...
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      Mentions: UCSD Robert N. Weinreb Academic Hospital Maastricht

    8. REPRODUCIBILITY OF VESSEL DENSITY MEASUREMENT WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EYES WITH AND WITHOUT RETINOPATHY

      Explore LWW Online Ophthalmology
      REPRODUCIBILITY OF VESSEL DENSITY MEASUREMENT WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EYES WITH AND WITHOUT RETINOPATHY
      Purpose: To determine the intravisit and intervisit reproducibility of optical coherence tomography angiography measurements of macular vessel density in eyes with and without retinal diseases. Methods: Fifteen healthy volunteers and 22 patients with retinal diseases underwent repeated optical coherence tomography angiography (Angiovue Imaging System, Optovue Inc) scans after pupil dilation on 2 separate visit days. For each visit day, the eyes were scanned twice. Vessel density defined as the proportion ...
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      Mentions: Optovue UCSD Robert N. Weinreb

    9. Estimating OCT Structural Measurement Floors to Improve Detection of Progression In Advanced Glaucoma

      Explore Elsevier Health Ophthalmology
      Estimating OCT Structural Measurement Floors to Improve Detection of Progression In Advanced Glaucoma
      Purpose Floor effects in retinal imaging are defined as the points at which no further structural loss can be detected. We estimated the measurement floors for spectral-domain optical coherence tomography (SD-OCT) measurements and compared global change over time in advanced glaucoma eyes. Design Validity study to investigate measurement floors. Methods A longitudinal Variability Group of 41 eyes with moderate to advanced glaucoma (SAP MD -8 dB) was used to estimate ...
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      Mentions: UCSD Robert N. Weinreb Christopher Bowd

    10. Diagnostic ability of peripapillary vessel density measurements of optical coherence tomography angiography in primary open-angle and angle-closure glaucoma

      Explore BJO Online Ophthalmology
      Diagnostic ability of peripapillary vessel density measurements of optical coherence tomography angiography in primary open-angle and angle-closure glaucoma
      Aims To evaluate the diagnostic ability of peripapillary vessel density measurements on optical coherence tomography angiography (OCTA) in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG), and to compare these with peripapillary retinal nerve fibre layer (RNFL) thickness measurements. Methods In a cross-sectional study, 48 eyes of 33 healthy control subjects, 63 eyes of 39 patients with POAG and 49 eyes of 32 patients with PACG underwent OCTA (RTVue-XR ...
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      Mentions: Optovue UCSD Robert N. Weinreb

    11. Deep Retinal Layer Microvasculature Dropout Detected by the Optical Coherence Tomography Angiography in Glaucoma

      Explore Elsevier Health Ophthalmology
      Deep Retinal Layer Microvasculature Dropout Detected by the Optical Coherence Tomography Angiography in Glaucoma
      Purpose To investigate factors associated with dropout of the parapapillary deep retinal layer microvasculature assessed by optical coherence tomography angiography (OCTA) in glaucomatous eyes. Design Cross-sectional study. Participants Seventy-one eyes from 71 primary open-angle glaucoma (POAG) patients with -zone parapapillary atrophy (PPA) enrolled in the Diagnostic Innovations in Glaucoma Study. Methods Parapapillary deep-layer microvasculature dropout was defined as a complete loss of the microvasculature located within the deep retinal layer ...
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      Mentions: UCSD Robert N. Weinreb Felipe A. Medeiros

    12. Relationship between Optical Coherence Tomography Angiography Vessel Density and Severity of Visual Field Loss in Glaucoma

      Explore Elsevier Health Ophthalmology
      Relationship between Optical Coherence Tomography Angiography Vessel Density and Severity of Visual Field Loss in Glaucoma
      Purpose To evaluate the association between vessel density measurements using optical coherence tomography angiography (OCT-A) and severity of visual field loss in primary open-angle glaucoma. Design Observational, cross-sectional study. Participants A total of 153 eyes from 31 healthy participants, 48 glaucoma suspects, and 74 glaucoma patients enrolled in the Diagnostic Innovations in Glaucoma Study. Methods All eyes underwent imaging using OCT-A (Angiovue; Optovue, Fremont, CA), spectral-domain OCT (Avanti; Optovue), and ...
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      Mentions: UCSD Robert N. Weinreb Felipe A. Medeiros

    13. The University of Colorado at Denver Receives NIH Grant for Photonics Monitoring and Modeling Core

      Explore Optical Coherence Tomography News Funding
      The University of Colorado at Denver Receives NIH Grant for Photonics Monitoring and Modeling Core
      The University of Colorado at Denver Received at 2016 NIH Grant for $691,303 for Photonics Monitoring and Modeling Core. The principal investigator is Matthew Brenner. The program beghan in 2016 and ends in 2017. Below is a summary of the proposed work. The Photonics Monitoring and Modeling Core (PMMC) consists of three core photonics based novel diagnostic technologies and a highly monitored mid-size animal model (rabbit) testing facility based ...
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      Mentions: National Institutes of Health UC Irvine UCSD

    14. Optical Coherence Tomography Angiography Vessel Density in Glaucomatous Eyes with Focal Lamina Cribrosa Defects

      Explore Elsevier Health Ophthalmology
      Optical Coherence Tomography Angiography Vessel Density in Glaucomatous Eyes with Focal Lamina Cribrosa Defects
      Purpose To investigate whether vessel density assessed by optical coherence tomography angiography (OCT-A) is reduced in glaucomatous eyes with focal lamina cribrosa (LC) defects. Design Cross-sectional, case-control study. Participants A total of 82 patients with primary open-angle glaucoma (POAG) from the Diagnostic Innovations in Glaucoma Study (DIGS) with and without focal LC defects (41 eyes of 41 patients in each group) matched by severity of visual field (VF) damage. Methods ...
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      Mentions: UCSD Robert N. Weinreb Felipe A. Medeiros

    15. Regional comparisons of optical coherence tomography angiography vessel density in primary open angle glaucoma

      Explore Elsevier Health Ophthalmology
      Regional comparisons of optical coherence tomography angiography vessel density in primary open angle glaucoma
      Purpose To compare the diagnostic abilities of the vessel densities in optic nerve head (ONH), peripapillary and macular regions measured using optical coherence tomography angiography (OCTA) in eyes with primary open angle glaucoma (POAG), and to evaluate the effect of glaucoma severity (based on the mean deviation, MD), optic disc size and pre-treatment intraocular pressure (IOP). Design Cross-sectional study Methods Seventy-eight eyes of 53 control subjects and 64 eyes of ...
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      Mentions: UCSD Robert N. Weinreb Harsha L. Rao

    16. Association between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography

      Explore Elsevier Health Ophthalmology
      Association between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography
      Purpose To evaluate the relationship between intraocular pressure (IOP) and rates of retinal nerve fiber layer (RNFL) thickness change over time measured by spectral-domain (SD) optical coherence tomography (OCT). Design Observational cohort study. Participants The study involved 547 eyes of 339 patients followed up for an average of 3.90.9 years. Three hundred eight (56.3%) had a diagnosis of glaucoma and 239 (43.7%) were considered glaucoma suspects ...
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      Mentions: UCSD Jeffrey M. Liebmann Robert N. Weinreb
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  4. About UCSD

    UCSD

    University of California at San Diego (UCSD) is a public research university in San Diego, California. UCSD is one of ten University of California campuses and was founded in 1955 around the pre-existing Scripps Institution of Oceanography.  UCSD Shiley Eye Center is part of the University of California at San Diego. Shiley Eye Center physicians, all of whom are faculty members of the UCSD School of Medicine.  Also see Hamilton Glaucoma Center.

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