1. UCSD

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    1. Mentioned In 233 Articles

    2. Performances of machine learning in detecting glaucoma using fundus and retinal optical coherence tomography images: A meta-analysis

      Performances of machine learning in detecting glaucoma using fundus and retinal optical coherence tomography images: A meta-analysis
      Purpose To evaluate the performance of machine learning (ML) in detecting glaucoma using fundus and retinal optical coherence tomography (OCT) images. Design Meta-analysis. Methods PubMed and EMBASE were searched on August 11, 2021. Bivariate random-effects model was used to pool ML's diagnostic sensitivity, specificity, and area under the curve (AUC). Subgroup analyses were performed based on ML classifier categories and dataset types. Results 105 (3.3%) studies were retrieved ...
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    3. Optical microangiography and progressive ganglion cell-inner plexiform layer loss in primary open angle glaucoma

      Optical microangiography and progressive ganglion cell-inner plexiform layer loss in primary open angle glaucoma
      Purpose To evaluate the association between optical microangiography (OMAG) measurements and progressive ganglion cell-inner plexiform layer (GCIPL) loss in primary open angle glaucoma (POAG). Design Prospective case-series Methods Sixty-three eyes of 38 POAG patients were studied for at least 2 years and with at least 3 optical coherence tomography (OCT) examinations. Only those hemifields with mild to moderate functional damage at baseline (106 hemifields) were included in the analysis. OMAG ...
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    4. Deep learning image analysis of optical coherence tomography angiography measured vessel density improves classification of healthy and glaucoma eyes

      Deep learning image analysis of optical coherence tomography angiography measured vessel density improves classification of healthy and glaucoma eyes
      Purpose : To compare convolutional neural network (CNN) analysis of en face vessel density images to gradient boosting classifier (GBC) analysis of instrument provided, feature-based optical coherence tomography angiography (OCTA) vessel density measurements and OCT RNFL thickness measurements for classifying healthy and glaucomatous eyes. Design : Comparison of diagnostic approaches Methods : 130 eyes of 80 healthy individuals and 275 eyes of 185 glaucoma patients with optic nerve head (ONH) OCTA and OCT ...
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      Mentions: UCSD
    5. Wide-field optical coherence tomography imaging in diabetic retinopathy

      Wide-field optical coherence tomography imaging in diabetic retinopathy
      Purpose: To report the individual retinal layer thicknesses up to mid-equator in patients with diabetic retinopathy (DR) using Spectralis (Heidelberg Engineering, Heidelberg, Germany) wide-field optical coherence tomography (OCT). Methods: Retinal layers were segmented using a custom designed semi-automated algorithm, where reference points were marked by the examiner to enable software to automatically compute the thickness values of each retinal sublayer at an interval of 1 mm from reference points. The ...
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    6. Optic Disc Microvasculature Dropout in Glaucoma Detected by Swept-Source Optical Coherence Tomography Angiography

      Optic Disc Microvasculature Dropout in Glaucoma Detected by Swept-Source Optical Coherence Tomography Angiography
      Purpose To assess the clinical utility of swept-source optical coherence tomography angiography (SS-OCTA) in detecting optic disc microvasculature dropout (MvD-D) in primary open-angle glaucoma (POAG) eyes. Design Cross sectional study. Methods One hundred and ninety-seven eyes of 197 POAG patients with acceptable-quality SS-OCTA (PLEX Elite 9000; Carl Zeiss Meditec, Dublin, CA, USA) images were enrolled. A whole-signal-mode 6.0 6.0-mm optic disc cube was obtained with projection artifact removal ...
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    7. Measurements of OCTA Complement OCT for Diagnosing Early Primary Open Angle Glaucoma

      Measurements of OCTA Complement OCT for Diagnosing Early Primary Open Angle Glaucoma
      Purpose: To compare measurements of global and regional circumpapillary capillary density (cpCD) with retinal nerve fiber layer (RNFL) thickness, and characterize their relationship with visual function in early primary open-angle glaucoma (POAG). Design: Cross-sectional study PARTICIPANTS: Eighty healthy eyes, 64 pre-perimetric, and 184 mild POAG eyes from the Diagnostic Innovations in Glaucoma Study. Methods: Global and regional RNFL thickness and cpCD measurements were obtained using optical coherence tomography (OCT) and ...
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      Mentions: UCSD
    8. Simultaneous directional full-field OCT using path-length and carrier multiplexing

      Simultaneous directional full-field OCT using path-length and carrier multiplexing
      Full-field swept-source optical coherence tomography (FF-SS-OCT) is an emerging technology with potential applications in ophthalmic imaging, microscopy, metrology, and other domains. Here we demonstrate a novel method of multiplexing FF-SS-OCT signals using carrier modulation (CM). The principle of CM could be used to inspect various properties of the scattered light, e.g. its spectrum, polarization, Doppler shift, or distribution in the pupil. The last of these will be explored in ...
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    9. Central macular OCTA parameters in glaucoma

      Central macular OCTA parameters in glaucoma
      Background/aims: To investigate the relationship between the foveal avascular zone (FAZ) parameters assessed by optical coherence tomography angiography (OCTA) and central visual field parameters in glaucoma and healthy subjects. Methods: One hundred and eighty-eight subjects (248 eyes), including 24 healthy (38 eyes), 37 glaucoma suspect (42 eyes, and 127 primary open angle glaucoma (POAG) patients (168 eyes), underwent imaging using OCTA and standard automated perimetry using the 24-2 and ...
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      Mentions: UCSD
    10. Macular Optical Coherence Tomography Imaging in Glaucoma

      Macular Optical Coherence Tomography Imaging in Glaucoma
      The advent of spectral-domain optical coherence tomography has played a transformative role in posterior segment imaging of the eye. Traditionally, images of the optic nerve head and the peripapillary area have been used to evaluate the structural changes associated with glaucoma. Recently, there is growing evidence in the literature supporting the use of macular spectral-domain optical coherence tomography as a complementary tool for clinical evaluation and research purposes in glaucoma.
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      Mentions: UCSD
    11. Strain by virtual extensometers and video-imaging optical coherence tomography as a repeatable metric for IOP-Induced optic nerve head deformations

      Strain by virtual extensometers and video-imaging optical coherence tomography as a repeatable metric for IOP-Induced optic nerve head deformations
      Purpose: To determine if in vivo strain response of the Optic Nerve Head (ONH) to IOP elevation visualized using Optical Coherence Tomography (OCT) video imaging and quantified using novel virtual extensometers was able to be provided repeatable measurements of tissue specific deformations. Methods: The ONHs of 5 eyes from 5 non-human primates (NHPs) were imaged by Spectralis OCT. A vertical and a horizontal B-scan of the ONH were continuously recorded ...
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    12. Individualized Glaucoma Change Detection Using Deep Learning Auto Encoder-Based Regions of Interest

      Individualized Glaucoma Change Detection Using Deep Learning Auto Encoder-Based Regions of Interest
      Purpose : To compare change over time in eye-specific optical coherence tomography (OCT) retinal nerve fiber layer (RNFL)-based region-of-interest (ROI) maps developed using unsupervised deep-learning auto-encoders (DL-AE) to circumpapillary RNFL (cpRNFL) thickness for the detection of glaucomatous progression. Methods : Forty-four progressing glaucoma eyes (by stereophotograph assessment), 189 nonprogressing glaucoma eyes (by stereophotograph assessment), and 109 healthy eyes were followed for 3 years with 4 visits using OCT. The San Diego ...
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      Mentions: UCSD
    13. Optical microangiography and progressive retinal nerve fiber layer loss in primary open angle glaucoma

      Optical microangiography and progressive retinal nerve fiber layer loss in primary open angle glaucoma
      Purpose : To evaluate the association between optical microangiography (OMAG) measurements and progressive retinal nerve fiber layer (RNFL) loss in primary open angle glaucoma (POAG). Design : Prospective case series Methods : Sixty-four eyes of 40 POAG patients (108 quadrants) with mild to moderate functional damage were longitudinally studied for at least 2 years and with a minimum of 3 optical coherence tomography (OCT) examinations. OMAG imaging was performed at the baseline visit ...
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    14. Long-Term Reproducibility of Optical Coherence Tomography Angiography in Stable Glaucomatous Eyes

      Long-Term Reproducibility of Optical Coherence Tomography Angiography in Stable Glaucomatous Eyes
      Purpose : To assess and compare long-term reproducibility of optical coherence tomography angiography (OCTA) vascular parameters and spectral-domain optical coherence tomography (OCT) thickness parameters in stable glaucoma, glaucoma suspect, and healthy eyes. Methods : A total of 88 eyes (15 healthy, 38 glaucoma suspect, and 35 non-progressive POAG) of 68 subjects were enrolled who had at least 3 visits within 1 to 1.5 years and both OCT and OCTA (Optovue Inc ...
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    15. Predicting central 10 degrees visual field from peripapillary optical coherence tomography using deep learning approach

      Predicting central 10 degrees visual field from peripapillary optical coherence tomography using deep learning approach
      Purpose: To develop a deep learning (DL) simulation of standard automated perimetry (SAP) in the central 10 based on spectral domain optical coherence tomography (SD-OCT) retinal nerve fiber layer thickness (RNFLT). Methods : This study included 5352 pairs of SD-OCT and 10-2 SAP from 1365 eyes of 724 healthy, glaucoma suspect and glaucoma patients from the Diagnostic Innovations in Glaucoma Study (DIGS) and the African Descent and Glaucoma Evaluation Study (ADAGES ...
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      Mentions: UCSD
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  2. About UCSD

    UCSD

    University of California at San Diego (UCSD) is a public research university in San Diego, California. UCSD is one of ten University of California campuses and was founded in 1955 around the pre-existing Scripps Institution of Oceanography.  UCSD Shiley Eye Center is part of the University of California at San Diego. Shiley Eye Center physicians, all of whom are faculty members of the UCSD School of Medicine.  Also see Hamilton Glaucoma Center.