Articles that mention UCSD -Optical Coherence Tomography News

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1. Mentioned In 197 Articles
2. Gradient Bosting Classifiers Combining Vessel Density and Tissue Thickness Measurements for Classifying Early to Moderate Glaucoma
  
  Explore American Journal of Ophthalmology Mar 25 2020 Ophthalmology
  
  Purpose To compare gradient boosting classifier (GBC) analysis of optical coherence tomography angiography (OCTA)-measured vessel density (VD) and OCT-measured tissue thickness to standard OCTA VD and OCT thickness parameters for classifying healthy eyes and eyes with early to moderate glaucoma. Design Comparison of diagnostic tools. Methods One-hundred-eight healthy eyes and 193 glaucomatous eyes with OCTA and OCT imaging of the macula and optic nerve head (ONH) were studied. Four ...
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  Mentions: UCSD Robert N. Weinreb Christopher Bowd
3. Researchers at OCT Medical Imaging Inc., along with researchers at Caltech and UCSD Develop Genetically Encodable and Acoustically Erasable Contrast Reagent for Optical Coherence Tomography
  
  Explore Optical Coherence Tomography News Feb 10 2020
  
  ... unambiguous assignment of their location. In this our group in association with researchers from Caltech and UCSD demonstrate the use of gas vesicles as reporter genes in bacterial colonies and as purified contrast age...
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  Mentions: California Institute of Technology UCSD OCT Medical Imaging Inc
4. Genetically Encodable Contrast Agents for Optical Coherence Tomography
  
  Explore ACS Publications Home Page Feb 9 2020
  
  Optical coherence tomography (OCT) has gained wide adoption in biological research and medical imaging due to its exceptional tissue penetration, 3D imaging speed and rich contrast. However, OCT plays a relatively small role in molecular and cellular imaging due to the lack of suitable biomolecular contrast agents. In particular, while the green fluorescent protein has provided revolutionary capabilities to fluorescence microscopy by connecting it to cellular functions such as gene ...
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  Mentions: California Institute of Technology UCSD OCT Medical Imaging Inc
5. Diagnostic Ability of Optical Coherence Tomography Angiography Macula Vessel Density for the Diagnosis of Glaucoma Using Difference Scan Sizes
  
  Explore LWW Online Feb 2 2020 Ophthalmology
  
  Prcis: There is diagnostic information in the outer region of OCTA macula scans not available in the inner region, and this information is especially useful in the early stages of glaucoma . Purpose: To evaluate the diagnostic accuracy of 33▒mm 2 and 66▒mm 2 macula OCT-A scans for classifying healthy, mild glaucoma , and moderate to severe glaucoma eyes. Methods: Participants enrolled in the Diagnostic Innovations in Glaucoma Study (DIGS ...
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  Mentions: Optovue University of São Paulo UCSD
6. Quantification of Retinal Nerve Fibre Layer Thickness on Optical Coherence Tomography with a Deep Learning Segmentation-Free Approach
  
  Explore Nature Publishing Group Jan 18 2020 Ophthalmology
  
  This study describes a segmentation-free deep learning (DL) algorithm for measuring retinal nerve fibre layer (RNFL) thickness on spectral-domain optical coherence tomography (SDOCT). The study included 25,285 B-scans from 1,338 eyes of 706 subjects. Training was done to predict RNFL thickness from raw unsegmented scans using conventional RNFL thickness measurements from good quality images as targets, forcing the DL algorithm to learn its own representation of RNFL. The ...
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  Mentions: UCSD Felipe A. Medeiros
7. Reflections on the Utility of the Retina as a Biomarker for Alzheimer’s Disease: A Literature Review
  
  Explore Home - Springer Dec 17 2019 Neurology , Ophthalmology
  
  As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimers disease (AD) pathology may manifest in the retina as a means to assess the state of the AD brain. The development and refinement of ophthalmologic techniques for studying the retina in vivo have produced evidence ...
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  Mentions: UCSD UCSF
8. Deep Learning Approaches Predict Glaucomatous Visual Field Damage from Optical Coherence Tomography Optic Nerve Head Enface Images and Retinal Nerve Fiber Layer Thickness Maps
  
  Explore ScienceDirect Oct 7 2019 Ophthalmology
  
  Purpose To develop and evaluate a deep learning system for differentiating between eyes with and without glaucomatous visual field damage (GVFD) and predicting the severity of GFVD from spectral domain optical coherence tomography (SDOCT) optic nerve head images. Design Evaluation of a diagnostic technology Participants 9,765 visual field (VF)SDOCT pairs collected from 1,194 participants with and without GVFD (1909 eyes). Methods Deep learning models were trained to ...
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  Mentions: Columbia University University of Alabama UCSD
9. Results of Optical Coherence Tomography Angiography and Visual Acuity Under Varying Contrast and Luminance Conditions
  
  Explore LWW Online Sep 23 2019 Ophthalmology
  
  Purpose: To assess early retinal microvascular and functional changes in diabetic patients without clinical evidence of diabetic retinopathy with optical coherence tomography angiography and central visual analyzer. Methods: This was an observational casecontrol study of diabetic patients without diabetic retinopathy and nondiabetic controls. Patients underwent optical coherence tomography angiography imaging and visual acuity testing using the central visual analyzer. The foveal avascular zone area and the capillary density in the ...
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  Mentions: Capital Medical University UCSD William R. Freeman
10. Coextensive synchronized SLO-OCT with adaptive optics for human retinal imaging
  
  Explore OSA | OSA Publishing Aug 27 2019 Ophthalmology
  
  We describe the details of a multimodal retinal imaging system which combines adaptive optics (AO) with an integrated scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT) imaging system. The OCT subsystem consisted of a swept-source, Fourier-domain mode-locked (FDML) laser, with a very high A-scan rate (1.6 MHz), whose beam was raster scanned on the retina by two scannersone resonant scanner and one galvanometer. The high sweep rate of ...
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  Mentions: John S. Werner Robert J. Zawadzki UCSD
11. Foveal Avascular Zone Distortion in Epiretinal Membrane by Optical Coherence Tomography Angiography
  
  Explore Healio.com May 23 2019 Ophthalmology
  
  BACKGROUND AND OBJECTIVE: To show the morphologic changes on the foveal avascular zone (FAZ) in patients with epiretinal membrane (ERM) using optical coherence tomography angiography (OCTA) and to demonstrate the correlation between distortion of FAZ and features of the ERM. PATIENTS AND METHODS: FAZ eccentricity index (longest diameter of FAZ/shortest diameter of FAZ) was measured in 52 patients with ERM and compared with 27 healthy subjects' values. The density ...
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  Mentions: UCSD William R. Freeman
12. Optical Coherence Tomography Angiography and Glaucoma: A Brief Review
  
  Explore Asia-Pacific Academy of Ophthalmology Apr 9 2019 Ophthalmology
  
  Optical coherence tomography angiography (OCTA) is a new modality in ocular imaging which provides non-invasive assessment and measurement of the vascular structures in the retina and optic nerve head. This technique provides useful information in glaucoma, such as quantitative assessment of vessel density. Vessel density measurement can be affected by various subject-related, eye-related, and diseaserelated factors. Overall, OCTA has good repeatability and reproducibility, and can differentiate glaucoma eyes from normal ...
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  Mentions: UCSD Robert N. Weinreb Harsha L. Rao
13. Association of Macular and Circumpapillary Microvasculature with Visual Field Sensitivity in Advanced Glaucoma
  
  Explore American Journal of Ophthalmology Mar 13 2019 Ophthalmology
  
  Purpose To evaluate the association between optical coherence tomography angiography (OCTA) macular and circumpapillary vessel density and visual field mean deviation (MD) in advanced primary open angle glaucoma (POAG). Design Cross-sectional study. Methods Macula (superficial layer) and optic nerve head [ONH, with (capillary density :CD) and without (vessel density: VD) automated removal of large vessels] OCTA of 34 eyes (34 patients, MD -10 dB) were investigated as macula whole image ...
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  Mentions: UCSD Robert N. Weinreb Christopher Bowd
14. Measurement floors and dynamic ranges of optical coherence tomography and angiography in glaucoma
  
  Explore ScienceDirect Mar 12 2019
  
  Purpose To determine if optical coherence tomography angiography (OCTA)derived vessel density measurements can extend the available dynamic range for detecting glaucoma compared to spectral-domain optical coherence tomography (SDOCT)derived thickness measurements. Design Observational, cross-sectional study. Participants A total of 509 eyes from 38 healthy participants, 63 glaucoma suspects and 193 glaucoma patients enrolled in the Diagnostic Innovations in Glaucoma Study. Methods Relative vessel density and tissue thickness measurement floors ...
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  Mentions: UCSD Robert N. Weinreb Christopher Bowd
15. UC San Diego Receives NIH Grant for Diagnostic Innovations in Glaucoma Study (DIGS): High Myoptia and Advanced Diseas
  
  Explore Optical Coherence Tomography News Mar 6 2019 Ophthalmology , Funding
  
  ...d reduce the costs of OAG management along the full continuum of OAG severity and range of refractive status. University of California at San Diego Receives a 2019 NIH Grant for $392,468 for Diagnostic Innovations in Gla...
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  Mentions: National Institutes of Health UCSD Linda M. Zangwill
16. Functional retinal imaging using adaptive optics swept-source OCT at 1.6 MHz
  
  Explore OSA | OSA Publishing Mar 1 2019
  
  Objective optical assessment of photoreceptor function may permit earlier diagnosis of retinal disease than current methods such as perimetry, electrophysiology, and clinical imaging. In this work, we describe an adaptive optics (AO) optical coherence tomography (OCT) system designed to measure functional responses of single cones to visible stimuli. The OCT subsystem consisted of a raster-scanning Fourier-domain mode-locked laser that acquires A scans at 1.64 MHz with a center wavelength ...
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  Mentions: John S. Werner Robert J. Zawadzki UCSD
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