1. UCSD

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    1. Mentioned In 251 Articles

    2. Combining OCT and OCT-Angiography Longitudinal Data for the Detection of Visual Field Progression in Glaucoma

      Combining OCT and OCT-Angiography Longitudinal Data for the Detection of Visual Field Progression in Glaucoma
      PURPOSE To use longitudinal optical coherence tomography (OCT) and OCT-Angiography (OCTA) data to detect glaucomatous visual field (VF) progression with a supervised machine learning approach. DESIGN Prospective cohort study. METHODS 110 eyes of glaucoma suspect (33.6%) and glaucoma (66.4%) patients with a minimum of five 24-2 VF tests and three optic nerve head and macula images over an average follow-up duration of 4.1 years were included. VF ...
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    3. Deep Learning Estimation of 10-2 Visual Field Map Based on Circumpapillary Retinal Nerve Fiber Layer Thickness Measurements

      Deep Learning Estimation of 10-2 Visual Field Map Based on Circumpapillary Retinal Nerve Fiber Layer Thickness Measurements
      PURPOSE : To estimate central 10 visual field (VF) map from spectral-domain optical coherence tomography (SD-OCT) retinal nerve fiber layer thickness (RNFL) measurements in glaucoma with artificial intelligence. DESIGN : Artificial intelligence (convolutional neural networks) study. METHODS : This study included 5352 SD-OCT and 10-2 VF pairs from 1365 eyes of 724 healthy, glaucoma suspect and glaucoma patients. Convolutional neural networks (CNN) were developed to estimate the 68 individual sensitivity thresholds of 10-2 ...
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    4. Joint Motion Correction and 3D Segmentation with Graph-Assisted Neural Networks for Retinal OCT

      Joint Motion Correction and 3D Segmentation with Graph-Assisted Neural Networks for Retinal OCT
      Optical Coherence Tomography (OCT) is a widely used non- invasive high resolution 3D imaging technique for biological tis- sues and plays an important role in ophthalmology. OCT retinal layer segmentation is a fundamental image processing step for OCT- Angiography projection, and disease analysis. A major problem in retinal imaging is the motion artifacts introduced by involuntary eye movements. In this paper, we propose neural networks that jointly correct eye motion ...
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    5. Universal photonics tomography

      Universal photonics tomography
      3D imaging is essential for the study and analysis of a wide variety of structures in numerous applications. Coherent photonic systems such as optical coherence tomography (OCT) and light detection and ranging (LiDAR) are state-of-the-art approaches, and their current implementation can operate in regimes that range from under a few millimeters to over more than a kilometer. We introduce a general method, which we call universal photonics tomography (UPT), for ...
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    6. Association of macular OCT and OCTA parameters with visual acuity in glaucoma

      Association of macular OCT and OCTA parameters with visual acuity in glaucoma
      Background/aims: To investigate the association of macular optical coherence tomography (OCT)/OCT angiography (OCTA) parameters with visual acuity (VA) in glaucoma. Methods: 144 pseudophakic primary open-angle glaucoma eyes were included. Foveal (fVD), parafoveal (pf), perifoveal (perifVD) and whole-image vessel densities (wiVD) of superficial and deep layers, and their corresponding ganglion cell complex (GCC) thicknesses were obtained from OCTA 66 mm 2 macula scans. Foveal avascular zone (FAZ) area, FAZ ...
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    7. A new technology ROTA developed by HKUMed and CU Medicine can visualise axonal fibre bundles on the retina to advance early diagnosis of glaucoma and optic neuropathies

      A new technology ROTA developed by HKUMed and CU Medicine can visualise axonal fibre bundles on the retina to advance early diagnosis of glaucoma and optic neuropathies
      ...4% higher than the current clinical standards. HKUMed is working with the University of California San Diego (UCSD), the United States, to apply ROTA in research and patient care, while patients can find the application ...
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    8. Frequency of Optical Coherence Tomography Testing to Detect Progression in Glaucoma

      Frequency of Optical Coherence Tomography Testing to Detect Progression in Glaucoma
      Purpose: To investigate the time to detect progression in glaucomatous eyes using different optical coherence tomography (OCT) test intervals. Methods: Participants with manifest glaucoma from the African Descent and Glaucoma Evaluation Study (ADAGES), a multicenter, prospective, observational cohort study, were included. A total of 2,699 OCT tests from 171 glaucomatous and 149 normal eyes of 182 participants, with at least 5 tests and 2 years of follow-up, were analyzed ...
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    9. Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans

      Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans
      Purpose: To compare the reproducibility of two-dimensional (2D) peripapillary retinal nerve fiber layer (RNFL) thickness and three-dimensional (3D) neuroretinal rim measurements using spectral domain optical coherence tomography (SDOCT) in normal and glaucoma subjects. Methods: One eye per subject for 27 normal and 40 glaucoma subjects underwent repeat SDOCT RNFL thickness scans and optic nerve volume scans on the same day. From the volume scan, custom software calculated five neuroretinal rim ...
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    10. Factors associated with choroidal microvascular dropout change

      Factors associated with choroidal microvascular dropout change
      Background/aims To investigate the factors associated with choroidal microvasculature drop-out (MvD) enlargement detected by optical coherence tomography angiography (OCT-A) in glaucomatous eyes. Methods Ninety-one eyes of 68 primary open-angle glaucoma patients were enrolled. Only eyes with a minimum of four good quality OCT-A and OCT scans of the optic nerve head acquired at least and with a minimum of 2 years follow-up were included. Area and angular circumference of ...
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    11. Comparison of Optic Disc Ovality Index and Rotation Angle Measurements in Myopic Eyes Using Photography and OCT Based Techniques

      Comparison of Optic Disc Ovality Index and Rotation Angle Measurements in Myopic Eyes Using Photography and OCT Based Techniques
      Purpose: To compare optic nerve head (ONH) ovality index and rotation angle measurements based on semi-automated delineation of the clinical ONH margin derived from photographs and automated BMO configuration derived from optical coherence tomography (OCT) images in healthy and glaucomatous eyes with high-, mild- and no axial myopia. Methods: One hundred seventy-five healthy and glaucomatous eyes of 146 study participants enrolled in the Diagnostic Innovations in Glaucoma Study (DIGS) with ...
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    12. Longitudinal Optical Coherence Tomography Angiography Findings in Malignant Hypertension Choroidopathy: A Case Report

      Longitudinal Optical Coherence Tomography Angiography Findings in Malignant Hypertension Choroidopathy: A Case Report
      This report presented the longitudinal optical coherence tomography angiography (OCTA) findings in a patient with malignant hypertension choroidopathy. An 87-year-old woman presented with acute unilateral central vision loss in the setting of hypertensive emergency. Spectral domain optical coherence tomography showed massive serous macular detachment. OCTA revealed extensive flow loss in the neuroretina and choriocapillaris. With blood pressure (BP) normalization and without any ocular intervention, visual acuity recovered on subsequent visits ...
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    13. Diagnostic accuracy of macular thickness map and texture en-face images for detecting glaucoma in eyes with axial high myopia

      Diagnostic accuracy of macular thickness map and texture en-face images for detecting glaucoma in eyes with axial high myopia
      To evaluate the diagnostic accuracy of a novel optical coherence tomography (OCT) texture-based en-face image analysis, called SALSA-Texture, that requires segmentation of only one retinal layer for glaucoma detection in eyes with axial high myopia, and to compare to standard macular ganglion cell-inner plexiform layer (GCIPL) thickness, macular retinal nerve fiber layer (mRNFL) thickness, and ganglion cell complex (GCC) thickness maps.
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    14. OCT Angiography Face Mask-associated Artifacts During the COVID-19 Pandemic

      OCT Angiography Face Mask-associated Artifacts During the COVID-19 Pandemic
      Prcis: Face mask wearing has no significant effects on artifacts or vessel density measurements in optic nerve head and macular OCT-Angiography scans. Purpose: To assess the difference in area of artifacts observed in optical coherence tomography angiography (OCT-A) scans with and without face mask wear and to verify if mask wear interferes with OCT-A vessel density measurements. Subjects and controls: 64 eyes of 10 healthy subjects, 4 ocular hypertensive, 8 ...
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    15. Nonlinear distortion correction for posterior eye segment optical coherence tomography with application to tree shrews

      Nonlinear distortion correction for posterior eye segment optical coherence tomography with application to tree shrews
      We propose an empirical distortion correction approach for optical coherence tomography (OCT) devices that use a fan-scanning pattern to image the posterior eye segment. Two types of reference markers were used to empirically estimate the distortion correction approach in tree shrew eyes: retinal curvature from MRI images and implanted glass beads of known diameter. Performance was tested by correcting distorted images of the optic nerve head. In small animal eyes ...
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    16. Association of Initial Optical Coherence Tomography Angiography Vessel Density Loss With Faster Visual Field Loss in Glaucoma

      Association of Initial Optical Coherence Tomography Angiography Vessel Density Loss With Faster Visual Field Loss in Glaucoma
      Importance: Rapid vessel density loss during an initial follow-up period may be associated with the rates of visual field loss over time. Objectives: To evaluate the association between the rate of vessel density loss during initial follow-up and the rate of visual field loss during an extended follow-up period in patients suspected of having glaucoma and patients with primary open-angle glaucoma. Design, setting, and participants: This retrospective cohort study assessed ...
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      Mentions: UCSD
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  2. About UCSD

    UCSD

    University of California at San Diego (UCSD) is a public research university in San Diego, California. UCSD is one of ten University of California campuses and was founded in 1955 around the pre-existing Scripps Institution of Oceanography.  UCSD Shiley Eye Center is part of the University of California at San Diego. Shiley Eye Center physicians, all of whom are faculty members of the UCSD School of Medicine.  Also see Hamilton Glaucoma Center.