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    1. Mentioned In 208 Articles

    2. Geometric Perfusion Deficits: A Novel OCT Angiography Biomarker for Diabetic Retinopathy Based on Oxygen Diffusion

      Geometric Perfusion Deficits: A Novel OCT Angiography Biomarker for Diabetic Retinopathy Based on Oxygen Diffusion
      Purpose To develop geometric perfusion deficits (GPD), an optical coherence tomography angiography (OCTA) biomarker based on oxygen diffusion, and to evaluate its utility in a pilot study of healthy subjects and patients with diabetic retinopathy (DR). Design Retrospective cross-sectional study. Methods Commercial spectral-domain OCTA instruments were used to acquire repeated 33 mm 2 and 66 mm 2 motion-corrected macular OCTA volumes. En face OCTA images corresponding to the superficial capillary ...
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    3. Impact of Pupil Dilation on Optical Coherence Tomography Angiography Retinal Microvasculature in Healthy Eyes

      Impact of Pupil Dilation on Optical Coherence Tomography Angiography Retinal Microvasculature in Healthy Eyes
      Prcis: Small but significant decreases in OCTA-measured circumpapillary capillary density were observed in healthy eyes dilated with 2.5% phenylephrine/0.5% tropicamide. Though likely clinically insignificant, ophthalmologists should consider these changes when interpreting OCTA results from dilated eyes. Purpose: To investigate the effect of pupil dilation using 2.5% phenylephrine and 0.5% tropicamide on quantitative assessment of retinal microvasculature using OCTA. Methods: OptoVue AngioVue high density (HD) and ...
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    4. Iridocorneal Angle Assessment After Laser Iridotomy with Swept-source Optical Coherence Tomography

      Iridocorneal Angle Assessment After Laser Iridotomy with Swept-source Optical Coherence Tomography
      Aim: To investigate the reliability of anterior chamber angle (ACA) measurements in narrow angles and assess the effect of laser peripheral iridotomy (LPI) on these measurements using novel swept-source optical coherence tomography (SS-OCT) technology. Methods: In this prospective observational study, patients with gonioscopically narrow angles were enrolled and scheduled for prophylactic LPI. Twelve ACA sections were obtained in each eye using SS-OCT (ANTERION, Heidelberg Engineering, Germany) before and after Nd ...
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    5. Evaluation of the clinical utility of optical coherence tomography angiography in age-related macular degeneration

      Evaluation of the clinical utility of optical coherence tomography angiography in age-related macular degeneration
      Background/Aims To evaluate the ability of optical coherence tomography angiography (OCTA) to identify the presence or absence of choroidal neovascularisation (CNV) and CNV activity in age-related macular degeneration (AMD). Methods Clinical parameters, fundus fluorescein angiogram and spectral-domain optical coherence tomography (SD-OCT) were used as the gold standard to determine disease activity. OCTA imaging was performed on the same day and was graded by two masked retina specialists for the ...
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    6. UCSD Receives NIH Grant for Deep Learning Approaches to Detect Glaucoma and Predict Progression from Spectral Domain Optical Coherence Tomography

      UCSD Receives NIH Grant for Deep Learning Approaches to Detect Glaucoma and Predict Progression from Spectral Domain Optical Coherence Tomography
      ...ills and experience to help ensure a successful transition into independence.

      University of California at San Diego Receives a 2020 NIH Grant for $117,347 for Deep Learning Approaches to D...

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    7. Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study

      Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study
      Purpose: To report the characteristics of non-proliferative fellow eyes in patients with unilateral proliferative macular telangiectasia type 2 (MacTel). Methods: This was a multicenter, retrospective study and included fellow eyes of eyes with subretinal neovascular membrane (SRNVM). Multimodal imaging including fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) was performed. OCT and OCTA measurements included central macular thickness (CMT), subfoveal choroidal thickness (SFCT), foveal avascular zone (FAZ) area ...
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    8. Capillary Density Measured by OCT Angiography in Glaucomatous Optic Disc Phenotypes

      Capillary Density Measured by OCT Angiography in Glaucomatous Optic Disc Phenotypes
      Purpose To compare optical coherence tomography angiography (OCTA) measured capillary density of the optic disc among four glaucomatous optic disc phenotypes. Design Cross-sectional study. Methods Circumpapillary capillary density (cpCD) of four glaucomatous optic disc phenotypes in 193 eyes of 141 glaucoma patients and cpCD in 92 eyes of 55 healthy subjects from the Diagnostic Innovations in Glaucoma Study (DIGS) were compared. Areas under the receiver operating characteristic curves (AUROC) were ...
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    9. Quantifying the Separation Between the Retinal Pigment Epithelium and Bruch's Membrane using Optical Coherence Tomography in Patients with Inherited Macular Degeneration

      Quantifying the Separation Between the Retinal Pigment Epithelium and Bruch's Membrane using Optical Coherence Tomography in Patients with Inherited Macular Degeneration
      Purpose : To describe and quantify Bruch's membrane (BM) and retinal pigment epithelium (RPE) separation using spectral-domain (SD) optical coherence tomography (OCT) in patients affected by inherited macular degenerations associated with BM thickening. Methods : Patients with molecularly confirmed Sorsby fundus dystrophy (SFD), dominant drusen (DD), and late-onset retinal degeneration (L-ORD) were included in this retrospective study. Each disease was classed as early stage if subjects were asymptomatic, intermediate stage if ...
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    10. Glaucomatous vertical vessel density asymmetry of the temporal raphe detected with optical coherence tomography angiography

      Glaucomatous vertical vessel density asymmetry of the temporal raphe detected with optical coherence tomography angiography
      Changes in retinal vasculature and ocular circulation may play an important role in the glaucoma development and progression. We evaluated the vertical asymmetry across the temporal raphe of the deep retinal layer vessel density, using swept-source optical coherence tomography angiography (SS-OCTA), and its relationship with the central visual field (VF) loss. Thirty-four eyes of 27 patients with open-angle glaucoma were included. SS-OCTA macular scanning was performed within a 3 3mm ...
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    11. Gradient Bosting Classifiers Combining Vessel Density and Tissue Thickness Measurements for Classifying Early to Moderate Glaucoma

      Gradient Bosting Classifiers Combining Vessel Density and Tissue Thickness Measurements for Classifying Early to Moderate Glaucoma
      Purpose To compare gradient boosting classifier (GBC) analysis of optical coherence tomography angiography (OCTA)-measured vessel density (VD) and OCT-measured tissue thickness to standard OCTA VD and OCT thickness parameters for classifying healthy eyes and eyes with early to moderate glaucoma. Design Comparison of diagnostic tools. Methods One-hundred-eight healthy eyes and 193 glaucomatous eyes with OCTA and OCT imaging of the macula and optic nerve head (ONH) were studied. Four ...
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    12. Researchers at OCT Medical Imaging Inc., along with researchers at Caltech and UCSD Develop Genetically Encodable and Acoustically Erasable Contrast Reagent for Optical Coherence Tomography

      Researchers at OCT Medical Imaging Inc., along with researchers at Caltech and UCSD Develop Genetically Encodable and Acoustically Erasable Contrast Reagent for Optical Coherence Tomography
      ... unambiguous assignment of their location. In this our group in association with researchers from Caltech and UCSD  demonstrate the use of gas vesicles as reporter genes in bacterial colonies and as purified contrast age...
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    13. Genetically Encodable Contrast Agents for Optical Coherence Tomography

      Genetically Encodable Contrast Agents for Optical Coherence Tomography
      Optical coherence tomography (OCT) has gained wide adoption in biological research and medical imaging due to its exceptional tissue penetration, 3D imaging speed and rich contrast. However, OCT plays a relatively small role in molecular and cellular imaging due to the lack of suitable biomolecular contrast agents. In particular, while the green fluorescent protein has provided revolutionary capabilities to fluorescence microscopy by connecting it to cellular functions such as gene ...
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    14. Diagnostic Ability of Optical Coherence Tomography Angiography Macula Vessel Density for the Diagnosis of Glaucoma Using Difference Scan Sizes

      Diagnostic Ability of Optical Coherence Tomography Angiography Macula Vessel Density for the Diagnosis of Glaucoma Using Difference Scan Sizes
      Prcis: There is diagnostic information in the outer region of OCTA macula scans not available in the inner region, and this information is especially useful in the early stages of glaucoma . Purpose: To evaluate the diagnostic accuracy of 33▒mm 2 and 66▒mm 2 macula OCT-A scans for classifying healthy, mild glaucoma , and moderate to severe glaucoma eyes. Methods: Participants enrolled in the Diagnostic Innovations in Glaucoma Study (DIGS ...
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  2. About UCSD

    UCSD

    University of California at San Diego (UCSD) is a public research university in San Diego, California. UCSD is one of ten University of California campuses and was founded in 1955 around the pre-existing Scripps Institution of Oceanography.  UCSD Shiley Eye Center is part of the University of California at San Diego. Shiley Eye Center physicians, all of whom are faculty members of the UCSD School of Medicine.  Also see Hamilton Glaucoma Center.