1. UCLA

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    1. Mentioned In 196 Articles

    2. Optical coherence tomography risk factors for development of late age related macular degeneration in the fellow eyes of patients enrolled in the HARBOR Study

      Optical coherence tomography risk factors for development of late age related macular degeneration in the fellow eyes of patients enrolled in the HARBOR Study
      Purpose To evaluate the relationship between optical coherence tomography (OCT) features and the progression to late age related macular degeneration (AMD) in the fellow eyes of patients enrolled in the 24-month HARBOR study (NCT00891735) for neovascular AMD. Design post hoc analysis of a phase 3 multicenter, prospective, randomized, double-masked, active treatment-controlled clinical trial. Participants Evaluable subjects (N=501) with macular neovascularization (MNV) secondary to neovascular AMD and early or intermediate ...
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    3. Macular Microvascular Networks In Healthy Pediatric Subjects

      Macular Microvascular Networks In Healthy Pediatric Subjects
      Purpose: To report optical coherence tomography angiography ( OCTA ) values in healthy pediatric eyes and to identify factors that may modify these values. Methods: In this prospective observational cross-sectional study, macular OCTA images were acquired from healthy pediatric patients. Main outcome measures were 1) foveal avascular zone (FAZ) area at the level of the superficial retinal capillary plexus (SCP); 2) SCP and deep retinal capillary plexus (DCP) perfusion density (based on ...
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    4. OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes

      OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes
      Purpose To assess anterior scleral canal opening (ASCO) offset relative to Bruchs membrane opening (BMO) (ASCO/BMO offset) so as to determine neural canal direction, obliqueness, and minimum cross-sectional area (NCMCA) in 362 healthy eyes. Design Cross-sectional study Methods After OCT optic nerve head (ONH) and retinal nerve fiber layer thickness (RNFLT) imaging, BMO and ASCO were manually segmented and planes, centroids, size and shape were calculated. Neural canal direction ...
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    5. Longitudinal Macular Structure-Function Relationships in Glaucoma and Their Sources of Variability

      Longitudinal Macular Structure-Function Relationships in Glaucoma and Their Sources of Variability
      Purpose 1) Review central structure-function (SF) relationships in glaucoma; 2) compare contributions of within-session and between-session variability to total variability of macular optical coherence tomography (OCT) thickness measurements; and 3) test the hypothesis that longitudinal within-eye variability of central SF relationships is smaller than between-individual variability. Methods We reviewed the pertinent literature on central SF relationships in glaucoma. Thirty-eight eyes (20 normal or glaucoma subjects) had 3 macular images per ...
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    6. Effect of segmentation error correction on optical coherence tomography angiography measurements in healthy subjects and diabetic macular oedema

      Effect of segmentation error correction on optical coherence tomography angiography measurements in healthy subjects and diabetic macular oedema
      Purpose To evaluate the impact of segmentation error on vessel density measurements in healthy eyes and eyes with diabetic macular oedema (DMO). Methods In this prospective, comparative, non-interventional study, enface optical coherence tomography angiography (OCTA) images of the macula from healthy eyes and eyes with DMO were acquired. Two expert graders assessed and corrected the segmentation error. The rate of segmentation error and the changes in vessel density and inner ...
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      Mentions: UCLA
    7. Fourier-domain mode-locked laser combined with a master-oscillator power amplifier architecture

      Fourier-domain mode-locked laser combined with a master-oscillator power amplifier architecture
      Originally introduced in 2005 for high-speed optical coherence tomography, the rapidly wavelength-swept Fourier-domain mode-locked (FDML) laser still, to this day, enables highest imaging speeds through a very high-speed spectral tuning capability. The FDML laser achieves a tuning bandwidth of over 1/10th of its center wavelength and can sweep this entire bandwidth in less than a microsecond. Interestingly, even though it covers a very broad spectral range, instantaneously it has ...
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      Mentions: Bahram Jalali UCLA
    8. Pearls and Pitfalls of Optical Coherence Tomography Angiography Imaging: A Review

      Pearls and Pitfalls of Optical Coherence Tomography Angiography Imaging: A Review
      Optical coherence tomography angiography (OCTA) has significantly expanded our knowledge of the ocular vasculature. Furthermore, this imaging modality has been widely adopted to investigate different ocular and systemic diseases. In this review, a discussion of the fundamental principles of OCTA is followed by the application of this imaging modality to study the retinal and choroidal vessels. A proper comprehension of this imaging modality is essential for the interpretation of OCTA ...
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    9. Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects

      Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects
      Background/Aims Hydroxychloroquine (HCQ) retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography (OCT) abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field (HVF) testing. Methods Data from patients with chronic HCQ exposure was obtained from seven tertiary care ...
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    10. Identification and Characterization of Imaging Technique Errors and Artifacts using Anterior Segment Optical Coherence Tomography for Irido-Corneal Angle Evaluations in Glaucom

      Identification and Characterization of Imaging Technique Errors and Artifacts using Anterior Segment Optical Coherence Tomography for Irido-Corneal Angle Evaluations in Glaucom
      Purpose Anterior segment optical coherence tomography (ASOCT) platforms provide non-invasive and quantifiable evaluations of anterior chamber angle (ACA) anatomy. Even though these ACA measurements have been validated with high repeatability and reproducibility, we are the first study to describe in detail the technique errors and artifacts that may occur during imaging of the ACA. The purpose of this study was to define the different types and quantify the frequency of ...
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    11. Optical coherence tomography imaging of presumed Cryptococcus neoformans infection localized to the retina

      Optical coherence tomography imaging of presumed Cryptococcus neoformans infection localized to the retina
      Purpose To report spectral-domain optical coherence tomography (SD-OCT) findings of presumed Cryptococcus neoformans infection limited to the retina . Methods We report a 39-year-old male with decreased vision for 3 months. Clinical examination revealed multiple cream-colored retinal lesions in the posterior pole of both eyes. SD-OCT demonstrated multiple areas of discrete, hyperreflective deposits in the inner retina, outer retina, and subretinal space without evidence of choroidal involvement. Fundus autofluorescence demonstrated areas ...
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      Mentions: UCLA
    12. UCLA Receives NIH Grant for Vitroretinal Surgery via Rogbotic Microsurgical System with Image Guidance, Force Feedback, Virtual Fixture, and Augmented Reality

      UCLA Receives NIH Grant for Vitroretinal Surgery via Rogbotic Microsurgical System with Image Guidance, Force Feedback, Virtual Fixture, and Augmented Reality
      ...e health outcomes and abate the costs associated with surgical complications.

      University of California at Los Angeles Receives a 2019 NIH Grant for $439,347 for Vitroretinal Surgery via Ro...

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    13. Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease

      Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease
      Purpose Automated spectral domain optical coherence tomography (SD-OCT) segmentation algorithms currently do not perform well in segmenting individual intraretinal layers in eyes with Stargardt disease (STGD). We compared selective B-scan segmentation strategies for generating mean retinal layer thickness and preserved area data from SD-OCT scans in patients with STGD1. Methods Forty-five eyes from 40 Stargardt patients were randomly selected from the ongoing Natural History of the Progression of Atrophy Secondary ...
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    14. Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success

      Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success
      On December 14 and 15 2018, over 1400 ophthalmologists participated in Rome at tha most important meeting on OCT and OCT Angiography. the 6th international meeting on OCT Angiography, advances in OCT . The organizer, Dr Lumbroso has, since he started to organize these meetings, a well-defined objective: informing ophthalmologist in any country on the new clinical possibilities of Ocular imaging. The policy is to invite the best speakers in the ...
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  2. About UCLA

    UCLA

    University of California at Los Angeles (UCLA) is a public research university located in Westwood, Los Angeles, California, United States. It was founded in 1919, making it the second-oldest general-purpose campus in the University of California system. The name was changed in 1927 to the University of California at Los Angeles. UCLA comprises the College of Letters and Science (the primary undergraduate college) as well as undergraduate colleges Arts and Architecture, Herb Alpert School of Music, Henry Samueli School of Engineering and Applied Science, Nursing, and Theater, Film, and Television, seven professional schools, and five professional Health Science schools. Since 2001, UCLA has enrolled over 33,000 total students annually, and that number is steadily rising.