1. UCLA

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    1. Mentioned In 311 Articles

    2. The OCT angular sign of Henle fiber layer (HFL) hyperreflectivity (ASHH) and the pathoanatomy of the HFL in macular disease

      The OCT angular sign of Henle fiber layer (HFL) hyperreflectivity (ASHH) and the pathoanatomy of the HFL in macular disease
      The Henle fiber layer (HFL) is comprised of bundles of unmyelinated photoreceptor axons intermingled with outer Mller cell processes. The photoreceptor axons extend from the cell bodies located in the outer nuclear layer and radially project toward the outer plexiform layer, the inner third of which includes the synaptic junctional complexes and the outer two-thirds of which includes the HFL. The oblique path of the HFL provides unique structural and ...
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    3. Overturning the mechanisms of cochlear amplification via area deformations of the organ of Corti

      Overturning the mechanisms of cochlear amplification via area deformations of the organ of Corti
      The mammalian ear embeds a cellular amplifier that boosts sound-induced hydromechanical waves as they propagate along the cochlea. The operation of this amplifier is not fully understood and is difficult to disentangle experimentally. In the prevailing view, cochlear waves are amplified by the piezo-electric action of the outer hair cells (OHCs), whose cycle-by-cycle elongations and contractions inject power into the local motion of the basilar membrane (BM). Concomitant deformations of ...
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      Mentions: UCLA
    4. Optical Coherence Tomography Biomarkers for Conversion to Exudative Neovascular Age-related Macular Degeneration

      Optical Coherence Tomography Biomarkers for Conversion to Exudative Neovascular Age-related Macular Degeneration
      Purpose To identify optical coherence tomography (OCT) biomarkers, including thin and thick double layer sign (DLS) for the progression from intermediate AMD (iAMD) to exudative macular neovascularization (MNV) over 24 months. Design Retrospective cohort study Methods Setting: Retina Consultants of Texas Patient Population 458 eyes of 458 subjects with iAMD in at least one eye with 24 months of follow-up data. Main Outcomes Measures The following biomarkers were assessed at ...
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      Mentions: UCLA
    5. Optical Coherence Tomography Risk Factors for Development of Atrophy in Eyes with Intermediate Age-related Macular Degeneration

      Optical Coherence Tomography Risk Factors for Development of Atrophy in Eyes with Intermediate Age-related Macular Degeneration
      Purpose To determine the frequency of multiple optical coherence tomography (OCT) biomarkers of intermediate age-related macular degeneration (iAMD) and their relationship with the development of complete retinal pigment epithelium and outer retinal atrophy (cRORA) after 2 years. Design Retrospective cohort study. Participants This retrospective analysis included 330 eyes of 330 consecutive patients with iAMD in at least one eye who had 24 months of follow-up data. Methods Spectralis OCT volumes ...
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      Mentions: UCLA
    6. Insights into the developing fovea revealed by imaging

      Insights into the developing fovea revealed by imaging
      Early development of the fovea has been documented by histological studies over the past few decades. However, structural distortion due to sample processing and the paucity of high-quality post-mortem tissue has limited the effectiveness of this approach. With the continuous progress in high-resolution non-invasive imaging technology, most notably optical coherence tomography (OCT) and OCT angiography (OCT-A), in vivo visualization of the developing retina has become possible. Combining the information from ...
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    7. A Metascore of Multiple Imaging Methods to Measure Long-Term Glaucoma Structural Progression

      A Metascore of Multiple Imaging Methods to Measure Long-Term Glaucoma Structural Progression
      Purpose : To develop a structural metascore (SMS) that combines measurements from different devices and expresses them on a single scale to facilitate their long-term analysis. Methods : Three structural measurements (Heidelberg Retina Tomograph II [HRT] rim area, HD-Cirrus optical coherence tomography [OCT] average retinal nerve fiber layer [RNFL] thickness, Spectralis OCT RNFL global thickness) were normalized on a scale of 0 to 100 and converted to a reference value. The resultant ...
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      Mentions: UCLA
    8. Current and Future Advanced Imaging Modalities for the Diagnosis of Early Osteoarthritis of the Hip

      Current and Future Advanced Imaging Modalities for the Diagnosis of Early Osteoarthritis of the Hip
      Hip osteoarthritis (OA) can be idiopathic or develop secondary to structural joint abnormalities of the hip joint (alteration of normal anatomy) and/or due to a systemic condition with joint involvement. Early osteoarthritic changes to the hip can be completely asymptomatic or may cause the development hip symptomatology without evidence of OA on radiographs. Delaying the progression of hip OA is critical due to the significant impact of this condition ...
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      Mentions: UCLA
    9. University of California at Los Angeles Received a 2022 NIH Grant for $567,451 for Intraocular Robotic Interventional and Surgical System for Automated Cataract Surgery

      University of California at Los Angeles Received a 2022 NIH Grant for $567,451 for Intraocular Robotic Interventional and Surgical System for Automated Cataract Surgery
      ...ning, and (3) robotic control over the intraocular lens implantation and positioning of the intraocular lens. University of California at Los Angeles Received a 2022 NIH Grant for $567,451 for Intraocular Robotic Interve...
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    10. Repeatability of new optical biometer and agreement with two validated optical biometers, all based on swept-source optical coherence tomography

      Repeatability of new optical biometer and agreement with two validated optical biometers, all based on swept-source optical coherence tomography
      Purpose: to evaluate the repeatability of the measurements provided by a new optical biometer (EyeStar 900, Haag-Streit) based on swept-source optical coherence tomography (SS- OCT) and their agreement with the measurements given by two validated biometers based on the same technology, the IOLMaster 700 (Carl Zeiss Meditec) and Argos (Movu). Setting: IRCCS G.B. Bietti Foundation, Rome, Italy. Design: Prospective evaluation of diagnostic test. Methods: In a series of unoperated ...
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    11. Age-related assessment of foveal avascular zone and surrounding capillary networks with swept source optical coherence tomography angiography in healthy eyes

      Age-related assessment of foveal avascular zone and surrounding capillary networks with swept source optical coherence tomography angiography in healthy eyes
      Aim To assess the macular capillary networks and foveal avascular zone (FAZ) with swept-source optical coherence tomography angiography in healthy eyes. Methods This cross-sectional, prospective, observational study enrolled 222 eyes of 116 healthy participants with no ocular or systemic disease. SS-OCTA images were captured using the PLEX Elite 9000 (Carl Zeiss Meditec Inc., Dublin, CA, USA) with a 66mm pattern centered on the foveal center. Vessel length density (VLD), perfusion ...
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      Mentions: UCLA
    12. Correlation of Diabetic Disease Severity to Degree of Quadrant Asymmetry in En Face OCTA Metrics

      Correlation of Diabetic Disease Severity to Degree of Quadrant Asymmetry in En Face OCTA Metrics
      Purpose: To determine if diabetic retinopathy (DR) severity affects quadrant asymmetry (QA) of optical coherence tomography angiography (OCTA) metrics differentially. Methods: Ninety eyes (60 patients) with no diabetes mellitus (DM) (n = 39) or varying levels of DR (n = 51) had OCTA images (3 3 mm, Cirrus5000) acquired five times and averaged. The vessel length density (VLD) and perfusion density (PD) of the superficial retinal layer (SRL) and deep retinal layer ...
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    13. Central Macular Topographic and Volumetric Measures: New Biomarkers for Detection of Glaucoma

      Central Macular Topographic and Volumetric Measures: New Biomarkers for Detection of Glaucoma
      Purpose : To test the hypothesis that newly developed shape measures using optical coherence tomography (OCT) macular volume scans can discriminate patients with perimetric glaucoma from healthy subjects. Methods : OCT structural measures defining macular topography and volume were recently developed based on cubic Bzier curves. We exported macular volume scans from 135 eyes with glaucoma (133 patients) and 155 healthy eyes (85 subjects) and estimated global and quadrant-based measures. The best ...
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      Mentions: UC Irvine UCLA
    14. Interplay between traveling wave propagation and amplification at the apex of the mouse cochlea

      Interplay between traveling wave propagation and amplification at the apex of the mouse cochlea
      Sounds entering the mammalian ear produce waves that travel from the base to the apex of the cochlea. An electro-mechanical active process amplifies traveling wave motions and enables sound processing over a broad range of frequencies and intensities. The cochlear amplifier requires combining the global traveling wave with the local cellular processes that change along the length of the cochlea given the gradual changes in hair cell and supporting cell ...
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      Mentions: UCLA
    15. Split-Window OCT biometry in pseudophakic eyes

      Split-Window OCT biometry in pseudophakic eyes
      Purpose: To determine the utility of Split-Window optical coherence tomography OCT (SW-OCT) biometry in measuring ocular axial dimensions as well as imaging the intraocular lens (IOL) and posterior capsule in pseudophakic eyes. Methods: Sixty-nine pseudophakic eyes of 69 subjects were enrolled in the study. The results of SW-OCT biometry implemented in the SD OCT device for posterior and anterior segment imaging (REVO NX, Optopol Technology) were compared with those obtained ...
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    16. Wedge Defects on Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors

      Wedge Defects on Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors
      Prcis: Among subjects with glaucoma, wedge-shaped defects on optical coherence tomography angiography (OCTA) were associated with disc hemorrhages (DH), paracentral visual field (VF) defects, increased cup-to-disc ratio (CDR), and thinner retinal nerve fiber layer (RNFL). Purpose: To examine determinants of wedge defects on peripapillary OCTA in glaucoma. Materials and Methods: A total of 278 eyes of 186 subjects with mild to severe primary open-angle glaucoma underwent 66 spectral-domain OCTA imaging ...
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      Mentions: UCLA
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  2. About UCLA

    UCLA

    University of California at Los Angeles (UCLA) is a public research university located in Westwood, Los Angeles, California, United States. It was founded in 1919, making it the second-oldest general-purpose campus in the University of California system. The name was changed in 1927 to the University of California at Los Angeles. UCLA comprises the College of Letters and Science (the primary undergraduate college) as well as undergraduate colleges Arts and Architecture, Herb Alpert School of Music, Henry Samueli School of Engineering and Applied Science, Nursing, and Theater, Film, and Television, seven professional schools, and five professional Health Science schools. Since 2001, UCLA has enrolled over 33,000 total students annually, and that number is steadily rising.