1. UCLA

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    1. Mentioned In 299 Articles

    2. Interplay between traveling wave propagation and amplification at the apex of the mouse cochlea

      Interplay between traveling wave propagation and amplification at the apex of the mouse cochlea
      Sounds entering the mammalian ear produce waves that travel from the base to the apex of the cochlea. An electro-mechanical active process amplifies traveling wave motions and enables sound processing over a broad range of frequencies and intensities. The cochlear amplifier requires combining the global traveling wave with the local cellular processes that change along the length of the cochlea given the gradual changes in hair cell and supporting cell ...
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      Mentions: UCLA
    3. Split-Window OCT biometry in pseudophakic eyes

      Split-Window OCT biometry in pseudophakic eyes
      Purpose: To determine the utility of Split-Window optical coherence tomography OCT (SW-OCT) biometry in measuring ocular axial dimensions as well as imaging the intraocular lens (IOL) and posterior capsule in pseudophakic eyes. Methods: Sixty-nine pseudophakic eyes of 69 subjects were enrolled in the study. The results of SW-OCT biometry implemented in the SD OCT device for posterior and anterior segment imaging (REVO NX, Optopol Technology) were compared with those obtained ...
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    4. Wedge Defects on Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors

      Wedge Defects on Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors
      Prcis: Among subjects with glaucoma, wedge-shaped defects on optical coherence tomography angiography (OCTA) were associated with disc hemorrhages (DH), paracentral visual field (VF) defects, increased cup-to-disc ratio (CDR), and thinner retinal nerve fiber layer (RNFL). Purpose: To examine determinants of wedge defects on peripapillary OCTA in glaucoma. Materials and Methods: A total of 278 eyes of 186 subjects with mild to severe primary open-angle glaucoma underwent 66 spectral-domain OCTA imaging ...
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      Mentions: UCLA
    5. Effect of OCT B-scan density on sensitivity for detection of intraretinal hyperreflective foci in eyes with age-related macular degeneration

      Effect of OCT B-scan density on sensitivity for detection of intraretinal hyperreflective foci in eyes with age-related macular degeneration
      Purpose To evaluate the impact of reducing the density of B-scans in an optical coherence tomography (OCT) volume on the sensitivity for detecting intraretinal hyperreflective foci (IHRF) in eyes with intermediate age-related macular degeneration (AMD) Methods A total of 165 eyes with intermediate AMD and IHRF were evaluated in this retrospective analysis. For each case, Cirrus HD-OCT volumes were imported into the reading center 3D-OCTOR software. The number of IHRF ...
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    6. Automated Retinal Vein Cannulation on Silicone Phantoms Using Optical-Coherence-Tomography-Guided Robotic Manipulations

      Automated Retinal Vein Cannulation on Silicone Phantoms Using Optical-Coherence-Tomography-Guided Robotic Manipulations
      Retinal vein occlusion is one of the most common causes of vision loss, occurring when a blood clot or other obstruction occludes a retinal vein. A potential remedy for retinal vein occlusion is retinal vein cannulation, a surgical procedure that involves infusing the occluded vein with a fibrinolytic drug to restore blood flow through the vascular lumen. This work presents an image-guided robotic system capable of performing automated cannulation on ...
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      Mentions: UCLA
    7. Vector of motion measurements in the living cochlea using a 3D OCT vibrometry system

      Vector of motion measurements in the living cochlea using a 3D OCT vibrometry system
      Optical coherence tomography (OCT) has become an important tool for measuring the vibratory response of the living cochlea. It stands alone in its capacity to measure the intricate motion of the hearing organ through the surrounding otic capsule bone. Nevertheless, as an extension of phase-sensitive OCT, it is only capable of measuring motion along the optical axis. Hence, measurements are 1-D. To overcome this limitation and provide a measure of ...
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    8. How Home Diagnostic Tools Will Alter the Future of Wet Age-Related Macular Degeneration

      How Home Diagnostic Tools Will Alter the Future of Wet Age-Related Macular Degeneration
      SriniVas R. Sadda, MD, looks to the future at the dawn of home diagnostics and home monitoring for patients with exudative age-related macular degeneration ( wet AMD ) through the promise and anticipated approval of at-home optical coherence tomography (OCT). Dr Sadda sees home OCT as a practice-changing advance in mitigating the burden of frequent office visits for patients and their families and as a part of the treat-and-extend approach, where intervals ...
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      Mentions: UCLA
    9. Agreement of intraocular lens power calculation between 2 SS-OCT–based biometers

      Agreement of intraocular lens power calculation between 2 SS-OCT–based biometers
      Purpose: To assess agreement of measurements by 2 swept-source optical coherence tomography biometers and to evaluate the prediction error (PE) in intraocular lens power calculation with 7 formulas. Setting: Tertiary public eye hospital. Design: Consecutive observational. Methods: Axial length (AL), keratometry (K), anterior chamber depth (ACD), lens thickness (LT), and corneal diameter (CD) were measured with the IOLMaster 700 (Biometer A) and Anterion (Biometer B). Agreement was quantified by the ...
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    10. Comparison of Iridocorneal Angle Assessments in Open-Angle Glaucoma and Ocular Hypertension Patients: Anterior Segment Optical Coherence Tomography and Gonioscopy

      Comparison of Iridocorneal Angle Assessments in Open-Angle Glaucoma and Ocular Hypertension Patients: Anterior Segment Optical Coherence Tomography and Gonioscopy
      Purpose: To quantitatively compare iridocorneal angle assessments using gonioscopy and anterior segment optical coherence tomography (AS-OCT). Patients: US and Chinese patients with open-angle glaucoma (OAG) and/or ocular hypertension (OHT). Methods: Analysis was pooled from 2 multicenter, noninterventional studies conducted in the US and China. Gonioscopy Shaffer grade and an AS-OCT method that approximates the angle width relative to local morphologic variations were compared by measuring the same iridocorneal angles ...
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    11. Navigating the White Dot Syndromes with Optical Coherence Tomography (OCT) and OCT Angiography (OCT-A)

      Navigating the White Dot Syndromes with Optical Coherence Tomography (OCT) and OCT Angiography (OCT-A)
      Introduction: White dot syndromes are a heterogeneous group of diseases that affect different layers in the retina and choroid. Multimodal imaging is fundamental in the diagnosis, but also can be crucial in unveiling the pathogenesis of these entities. Material and methods: Literature review. Results: Optical coherence tomography (OCT) provides depth-resolved, histological grade images of the vitreous, retina, and choroid. This technology is very useful to localize the primary nature and ...
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      Mentions: UCLA
    12. Intrasession Repeatability and Intersession Reproducibility of Macular Vessel Parameters on Optical Coherence Tomography Angiography in Glaucomatous and Non-Glaucomatous Eyes

      Intrasession Repeatability and Intersession Reproducibility of Macular Vessel Parameters on Optical Coherence Tomography Angiography in Glaucomatous and Non-Glaucomatous Eyes
      Purpose: Using optical coherence tomography angiography (OCTA), this study compared intrasession repeatability versus intersession reproducibility of macular vessel parameters in glaucoma and non-glaucoma subjects. Methods: 6x6 mm 2 macular OCTA scans (Cirrus HD-OCT 5000) were acquired from glaucomatous and non-glaucomatous subjects as part of an observational, longitudinal study. Vessel area density (VAD) and vessel skeleton density (VSD) were calculated using research-based quantification software while perfusion density (PD Z ) and vessel ...
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    13. Correlation between Fundus Autofluorescence and En Face Optical Coherence Tomography Measurements of Geographic Atrophy

      Correlation between Fundus Autofluorescence and En Face Optical Coherence Tomography Measurements of Geographic Atrophy
      Purpose: To evaluate the correlation between fundus autofluorescence (FAF) and en face spectral-domain optical coherence tomography (SDOCT) measurements of geographic atrophy (GA) associated with age-related macular degeneration (AMD). Design: Retrospective, cross-sectional study. Participants: 270 eyes from 172 subjects with GA associated with AMD. Methods: Subjects with atrophic AMD with both fundus autofluorescence (FAF; Heidelberg HRA + Spectralis) and dense volume (128 B-scans over 6x6mm) spectral domain optical coherence tomography (SDOCT; Cirrus ...
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      Mentions: UCLA
    14. Impact of signal strength on quantitative retinal and choriocapillaris flow measurement from optical coherence tomography angiography

      Impact of signal strength on quantitative retinal and choriocapillaris flow measurement from optical coherence tomography angiography
      We evaluated the impact of signal strength (SS) on quantitative measurements from optical coherence tomography (OCTA). Twenty healthy-volunteers were included. A neutral density filter (NDF) was attached to spectral-domain OCTA (SD-OCTA) and swept-source OCTA (SS-OCTA). All subjects were imaged with both devices three times using three different conditions: no filter, NDF0.3, and NDF0.6. For SD-OCTA, SS decreased from 10.0 to 8.2 and 4.0 with the ...
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    15. Angle closure extent, anterior segment dimensions and intraocular pressure

      Angle closure extent, anterior segment dimensions and intraocular pressure
      Aim To investigate the association between the extent of iridotrabecular contact and other quantitative anterior segment dimensions measured by swept-source optical coherence tomography (SS-OCT; CASIA SS-1000, Tomey, Nagoya, Japan) with intraocular pressure (IOP). Methods Cross-sectional study. All subjects who were 50 years with no history of glaucoma, ocular surgery or trauma, underwent SS-OCT imaging (eight equally spaced radial scans), Goldman applanation tonometry and gonioscopy on the same day. We measured ...
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  2. About UCLA

    UCLA

    University of California at Los Angeles (UCLA) is a public research university located in Westwood, Los Angeles, California, United States. It was founded in 1919, making it the second-oldest general-purpose campus in the University of California system. The name was changed in 1927 to the University of California at Los Angeles. UCLA comprises the College of Letters and Science (the primary undergraduate college) as well as undergraduate colleges Arts and Architecture, Herb Alpert School of Music, Henry Samueli School of Engineering and Applied Science, Nursing, and Theater, Film, and Television, seven professional schools, and five professional Health Science schools. Since 2001, UCLA has enrolled over 33,000 total students annually, and that number is steadily rising.