1. UC Irvine

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    1. Mentioned In 275 Articles

    2. Volumetric laser endomicroscopy in the management of Barrett's esophagus

      Volumetric laser endomicroscopy in the management of Barrett's esophagus
      Purpose of review: The incidence of esophageal adenocarcinoma is on the rise despite widespread appreciation that the precursor lesion is Barrett's esophagus. Studies have shown that some patients known to have Barrett's esophagus develop cancer despite their enrollment in conventional endoscopic surveillance programs. This highlights the need for advanced endoscopic imaging to help identify early neoplasia and prevent its progression to esophageal cancer. Recently, a wide-field, second-generation optical ...
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    3. Dynamically focused optical coherence tomography for endoscopic applications

      Dynamically focused optical coherence tomography for endoscopic applications
      We report a demonstration of a small liquid-filled polymer lens that may be used to dynamically provide scanning depth focus for endoscopic optical coherence tomography (OCT) applications. The focal depth of the lens is controlled by changing the hydraulic pressure within the lens, enabling dynamic focal depth control without the need for articulated parts. The 1 mm diameter lens is shown to have resolving power of 5 m, and can ...
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    4. Ultra-deep imaging of optical coherence tomography in highly scattering media

      Ultra-deep imaging of optical coherence tomography in highly scattering media
      A time-domain optical coherence tomography system based on measuring the reflection matrix of back-scattered light is proposed for extended imaging depth into scattering media. A filtering operation is applied to the reflection matrix to preserve the back-scattered light with near-forward directions while discarding most of the multiple scattered light. A singular value decomposition is then carried out in the filtered matrix for principal component analysis, to remove the residual multi-scattered ...
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    5. Coagulation monitoring based on blood elastic measurement using optical coherence tomography

      Coagulation monitoring based on blood elastic measurement using optical coherence tomography
      Blood coagulation monitoring is important to diagnose hematological diseases and cardiovascular diseases and to predict the risk of bleeding and excessive clotting. In this study, we developed a system to dynamically monitor blood coagulation and quantitatively determine the coagulation function by blood elastic measurement. When blood forms a clot from a liquid, ultrasonic force induces a shear wave, which is detected by optical coherence tomography (OCT). The coagulation of porcine ...
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    6. Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images

      Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images
      Doppler optical coherence tomography (DOCT) is considered one of the most promising functional imaging modalities for neuro biology research and has demonstrated the ability to quantify cerebral blood flow velocity at a high accuracy. However, the measurement of total absolute blood flow velocity (BFV) of major cerebral arteries is still a difficult problem since it not only relates to the properties of the laser and the scattering particles, but also ...
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    7. UC Irvine Receives NIH Grant for Development of Real-Time Optical Coherence Elastography System to Quantify The Mechanical Properties of Retinal Layers In-Vivo

      UC Irvine Receives NIH Grant  for Development of Real-Time Optical Coherence Elastography System to Quantify The Mechanical Properties of Retinal Layers In-Vivo
      ...physicians more information about the onset and progression of AMD in order t

      University of California at Irvine Receives a 2017 NIH Grant for $43,576 for Development of Real-Time Optical ...

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    8. Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging

      Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging
      We present a tri-modality imaging system and fully integrated tri-modality probe for intravascular imaging. The tri-modality imaging system is able to simultaneously acquire optical coherence tomography (OCT), ultrasound (US), and fluorescence imaging. Moreover, for fluorescence imaging, we used the FDA-approved indocyanine green (ICG) dye as the contrast agent to target lipid-loaded macrophages. We conducted imaging from a male New Zealand white rabbit to evaluate the performance of the tri-modality system ...
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    9. Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome

      Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome
      Context: Cortisol has been suggested as a risk factor for choroidal thickening, which may lead to retinal changes. Objective: To compare choroidal thickness measurements using optical coherence tomography (OCT) in patients with endogenous active Cushings syndrome (CS) and to evaluate the occurrence of retinal abnormalities in the same group of patients. Design: Cross-sectional study. Setting: Outpatient clinic. Patients: Eleven female patients with CS in hypercortisolism state as determined by the ...
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    10. Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor

      Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor
      The upper airway is a complex tissue structure that is prone to collapse. Current methods for studying airway obstruction are inadequate in safety, cost, or availability, such as CT or MRI, or only provide localized qualitative information such as flexible endoscopy. Long range optical coherence tomography (OCT) has been used to visualize the human airway in vivo , however the limited imaging range has prevented full delineation of the various shapes ...
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    11. 3D mapping of elastic modulus using shear wave optical micro-elastography

      3D mapping of elastic modulus using shear wave optical micro-elastography
      lastography provides a powerful tool for histopathological identification and clinical diagnosis based on information from tissue stiffness. Benefiting from high resolution, three-dimensional (3D), and noninvasive optical coherence tomography (OCT), optical micro-elastography has the ability to determine elastic properties with a resolution of ~10m in a 3D specimen. The shear wave velocity measurement can be used to quantify the elastic modulus. However, in current methods, shear waves are measured near the ...
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    12. Biomedical Optics in Otorhinolaryngology (Textbook)

      Biomedical Optics in Otorhinolaryngology (Textbook)
      Biomedical Optics in Otorhinolaryngology: Head and Neck Surgery gives an overview of current technology in biomedical optics relevant to the field of Otorhinolaryngology and head and neck surgery. It provides a comprehensive source of knowledge for researchers and active clinicians seeking information on the principles and practical use of novel diagnostic and therapeutic technology. While most books focus exclusively on laser surgery, which has been largely unchanged for the past ...
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    13. Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography

      Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography
      Objectives/Hypothesis Current imaging modalities lack the necessary resolution to diagnose subglottic stenosis. The aim of this study was to use optical coherence tomography (OCT) to evaluate nascent subglottic mucosal injury and characterize mucosal thickness and structural changes using texture analysis in a simulated intubation rabbit model. Study Design Prospective animal study in rabbits. Methods Three-centimeter-long sections of endotracheal tubes (ETT) were endoscopically placed in the subglottis and proximal trachea ...
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    14. 1-15 of 275 1 2 3 4 ... 17 18 19 »
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  2. About UC Irvine

    UC Irvine

    The University of California at Irvine is a public research university situated in Irvine, California. Founded in 1965, it is the second-youngest University of California campus.   Beckman Laser Institute at the University of California in Irvine. The BLI mission is to serve as the world's leading interdisciplinary center for Biomedical Optics.