1. UC Irvine

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    1. Mentioned In 283 Articles

    2. Miniature probe for mapping mechanical properties of vascular lesions using acoustic radiation force optical coherence elastography

      Miniature probe for mapping mechanical properties of vascular lesions using acoustic radiation force optical coherence elastography
      Cardiovascular diseases are the leading cause of fatalities in the United States. Atherosclerotic plaques are one of the primary complications that can lead to strokes and heart attacks if left untreated. It is essential to diagnose the disease early and distinguish vulnerable plaques from harmless ones. Many methods focus on the structural or molecular properties of plaques. Mechanical properties have been shown to change drastically when abnormalities develop in arterial ...
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    3. Three-dimensional optical coherence tomography reconstruction of bifurcation stenting using the Szabo anchor-wire technique

      Three-dimensional optical coherence tomography reconstruction of bifurcation stenting using the Szabo anchor-wire technique
      Ostial lesions present unique challenges for percutaneous coronary intervention (PCI). These lesions are often more calcified, fibrotic, rigid, and more prone to elastic recoil. Intervention on these lesions is associated with higher procedural complications and higher rates of restenosis. Ostial lesions require precise stent placement in the ostium with the absence of side branch compromise. Accurate stent placement in the ostium without side branch compromise is difficult to accomplish with ...
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      Mentions: UC Irvine
    4. Longitudinal shear wave imaging for elasticity mapping using optical coherence elastography

      Longitudinal shear wave imaging for elasticity mapping using optical coherence elastography
      Shear wave measurements for the determination of tissue elastic properties have been used in clinical diagnosis and soft tissue assessment. A shear wave propagates as a transverse wave where vibration is perpendicular to the wave propagation direction. Previous transverse shear wave measurements could detect the shear modulus in the lateral region of the force; however, they could not provide the elastic information in the axial region of the force. In ...
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    5. Extended axial imaging range, widefield swept source optical coherence tomography angiography

      Extended axial imaging range, widefield swept source optical coherence tomography angiography
      We developed a high-speed, swept source OCT system for widefield OCT angiography (OCTA) imaging. The system has an extended axial imaging range of 6.6 mm. An electrical lens is used for fast, automatic focusing. The recently developed split-spectrum amplitude and phase-gradient angiography allow high-resolution OCTA imaging with only two B-scan repetitions. An improved post-processing algorithm effectively removed trigger jitter artifacts and reduced noise in the flow signal. We demonstrated ...
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    6. UC Irving Receives NIH Grant for Phase Resolved ARF Optical Coherence Elastrography for Intravascular Imaging

      UC Irving Receives NIH Grant for Phase Resolved ARF Optical Coherence Elastrography for Intravascular Imaging
      University of California at Irving Receives a 2017 NIH Grant for $659,953 for Phase Resolved ARF Optical Coherence Elastrography for Intravascular Imaging. The principal investigator is Zhongping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography ...
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    7. NinePoint Medical to Feature the NvisionVLE® Imaging System with Real-time Targeting™ at DDW 2017; Twenty-four Scientific Abstracts to be Presented

      NinePoint Medical to Feature the NvisionVLE® Imaging System with Real-time Targeting™ at DDW 2017; Twenty-four Scientific Abstracts to be Presented
      ... targeting potential disease that may exist below the surface of the esophagus, stated Dr. Kenneth Chang, MD, University of California Irvine Medical Center, Professor and Chief, Division of Gastroenterology. Finding dys...
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    8. Volumetric laser endomicroscopy in the management of Barrett's esophagus

      Volumetric laser endomicroscopy in the management of Barrett's esophagus
      Purpose of review: The incidence of esophageal adenocarcinoma is on the rise despite widespread appreciation that the precursor lesion is Barrett's esophagus. Studies have shown that some patients known to have Barrett's esophagus develop cancer despite their enrollment in conventional endoscopic surveillance programs. This highlights the need for advanced endoscopic imaging to help identify early neoplasia and prevent its progression to esophageal cancer. Recently, a wide-field, second-generation optical ...
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    9. Dynamically focused optical coherence tomography for endoscopic applications

      Dynamically focused optical coherence tomography for endoscopic applications
      We report a demonstration of a small liquid-filled polymer lens that may be used to dynamically provide scanning depth focus for endoscopic optical coherence tomography (OCT) applications. The focal depth of the lens is controlled by changing the hydraulic pressure within the lens, enabling dynamic focal depth control without the need for articulated parts. The 1 mm diameter lens is shown to have resolving power of 5 m, and can ...
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    10. Ultra-deep imaging of optical coherence tomography in highly scattering media

      Ultra-deep imaging of optical coherence tomography in highly scattering media
      A time-domain optical coherence tomography system based on measuring the reflection matrix of back-scattered light is proposed for extended imaging depth into scattering media. A filtering operation is applied to the reflection matrix to preserve the back-scattered light with near-forward directions while discarding most of the multiple scattered light. A singular value decomposition is then carried out in the filtered matrix for principal component analysis, to remove the residual multi-scattered ...
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    11. Coagulation monitoring based on blood elastic measurement using optical coherence tomography

      Coagulation monitoring based on blood elastic measurement using optical coherence tomography
      Blood coagulation monitoring is important to diagnose hematological diseases and cardiovascular diseases and to predict the risk of bleeding and excessive clotting. In this study, we developed a system to dynamically monitor blood coagulation and quantitatively determine the coagulation function by blood elastic measurement. When blood forms a clot from a liquid, ultrasonic force induces a shear wave, which is detected by optical coherence tomography (OCT). The coagulation of porcine ...
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    12. Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images

      Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images
      Doppler optical coherence tomography (DOCT) is considered one of the most promising functional imaging modalities for neuro biology research and has demonstrated the ability to quantify cerebral blood flow velocity at a high accuracy. However, the measurement of total absolute blood flow velocity (BFV) of major cerebral arteries is still a difficult problem since it not only relates to the properties of the laser and the scattering particles, but also ...
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    13. UC Irvine Receives NIH Grant for Development of Real-Time Optical Coherence Elastography System to Quantify The Mechanical Properties of Retinal Layers In-Vivo

      UC Irvine Receives NIH Grant  for Development of Real-Time Optical Coherence Elastography System to Quantify The Mechanical Properties of Retinal Layers In-Vivo
      ...physicians more information about the onset and progression of AMD in order t

      University of California at Irvine Receives a 2017 NIH Grant for $43,576 for Development of Real-Time Optical ...

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  2. About UC Irvine

    UC Irvine

    The University of California at Irvine is a public research university situated in Irvine, California. Founded in 1965, it is the second-youngest University of California campus.   Beckman Laser Institute at the University of California in Irvine. The BLI mission is to serve as the world's leading interdisciplinary center for Biomedical Optics.