1. UC Irvine

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    1. Mentioned In 339 Articles

    2. Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

      Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma
      The purpose of this pilot study is to examine the treatment basal cell carcinoma (BCC) with laser technology under the guidance of optical coherence tomography imaging (OCT). The laser modality that we plan to use is the long-pulse Nd:YAG 1064nm laser, which is a non-ablative laser already shown to effectively treat BCC. Laser treatment of BCC has limited precedent in the literature, but the addition of OCT has the ...
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      Mentions: UC Irvine
    3. Feasibility and safety of tethered capsule endomicroscopy in patients with Barrett’s esophagus in a multi-center study

      Feasibility and safety of tethered capsule endomicroscopy in patients with Barrett’s esophagus in a multi-center study
      Background Aims Tethered capsule endomicroscopy (TCE) involves swallowing small tethered pill that implements optical coherence tomography (OCT) imaging, procuring high resolution images of the whole esophagus. Here, we demonstrate and evaluate the feasibility and safety of TCE and a portable OCT imaging system in patients with Barretts esophagus (BE) in a multi-center (5-site) clinical study. Methods Untreated patients with BE as per endoscopic biopsy diagnosis were eligible to participate in ...
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    4. Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy

      Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
      We have recently developed and optimized a vaginal Optical Coherence tomography /angiography endoscopy imaging system. This technology is able to obtain a comprehensive image of the vaginal epithelium, blood vessels, and lamina propria. The primary focus of this study is establishing the Optical Coherence Tomography system's capability of capturing vaginal changes that occur before and after menopause, as well as before and after treatment with fractional-CO2 laser therapy.
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      Mentions: UC Irvine
    5. Reflectance Confocal Microscopy, Optical Coherence Tomography, and Multiphoton Microscopy in Inflammatory Skin Disease Diagnosis

      Reflectance Confocal Microscopy, Optical Coherence Tomography, and Multiphoton Microscopy in Inflammatory Skin Disease Diagnosis
      Background and objectives: Technological advances in medicine have brought about many novel skin imaging devices. This review aims to evaluate the scientific evidence supporting the use of noninvasive optical imaging techniques to aid in the diagnosis and prognosis of inflammatory skin diseases. Study design/materials and methods: PubMed and Scopus were searched in September 2020 according to PRISMA guidelines for articles using reflectance confocal microscopy (RCM), optical coherence tomography (OCT ...
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      Mentions: UC Irvine
    6. Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders

      Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders
      Purpose Optical coherence tomography (OCT) captures retinal damage in neuromyelitis optica spectrum disorders (NMOSD). Previous studies investigating OCT in NMOSD have been limited by the rareness and heterogeneity of the disease. The goal of this study was to establish an image repository platform, which will facilitate neuroimaging studies in NMOSD. Here we summarise the profile of the Collaborative OCT in NMOSD repository as the initial effort in establishing this platform ...
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    7. 2D Ultrasonic Array-based Optical Coherence Elastography

      2D Ultrasonic Array-based Optical Coherence Elastography
      Acoustic radiation force optical coherence elastography (ARF-OCE) has been successfully implemented to characterize the biomechanical properties of soft tissues such as the cornea and the retina with high resolution using single-element ultrasonic transducers for ARF excitation. Most currently proposed OCE techniques, such as air-puff and ARF, have less capability to control the spatiotemporal information of the induced region of deformation, resulting in limited accuracy and low temporal resolution of the ...
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    8. Advances in Doppler optical coherence tomography and angiography

      Advances in Doppler optical coherence tomography and angiography
      Since the first demonstration of Doppler optical coherence tomography (OCT) in 1997, several functional extensions of Doppler OCT have been developed, including velocimetry, angiogram, and optical coherence elastography. These functional techniques have been widely used in research and clinical applications, particularly in ophthalmology. Here, we review the principles, representative methods, and applications of different Doppler OCT techniques, followed by discussion on the innovations, limitations, and future directions of each of ...
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      Mentions: UC Irvine
    9. Combining Deep Learning With Optical Coherence Tomography Imaging to Determine Scalp Hair and Follicle Counts

      Combining Deep Learning With Optical Coherence Tomography Imaging to Determine Scalp Hair and Follicle Counts
      Background and Objectives One of the challenges in developing effective hair loss therapies is the lack of reliable methods to monitor treatment response or alopecia progression. In this study, we propose the use of optical coherence tomography (OCT) and automated deep learning to non‐invasively evaluate hair and follicle counts that may be used to monitor the success of hair growth therapy more accurately and efficiently. Study Design/Materials and ...
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    10. Effect of panretinal photocoagulation on macular vasculature using optical coherence tomography angiography

      Effect of panretinal photocoagulation on macular vasculature using optical coherence tomography angiography
      Background: To evaluate the changes of macular vascular density in the superficial capillary (SCP) and the deep capillary plexus (DCP), foveal avascular area (FAZ), choroidal flow, and macular thickness after pan-retinal photocoagulation (PRP). Methods: In this prospective interventional non-comparative case series, patients with very severe nonproliferative (NPDR) and early proliferative diabetic retinopathy (PDR) and no significant macular edema who were candidates for pan-retinal photocoagulation underwent measurement of corrected distance visual ...
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      Mentions: UC Irvine
    11. Imaging of in vivo pseudoxanthoma elasticum via multiphoton microscopy and optical coherence tomography

      Imaging of in vivo pseudoxanthoma elasticum via multiphoton microscopy and optical coherence tomography
      Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder of abnormal elastic tissue deposition and calcification. 1 PXE primarily affects the elastic fibers in the dermis of the skin, Bruch membrane of the eye, and the media and intima of mid-sized arteries. The skin findings may present as small yellow, orange, or cream-colored papules, resembling plucked-chicken skin or cobblestone. The skin on the neck and skin flexures may be lax and ...
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      Mentions: UC Irvine
    12. Coupling Pressure Sensing with Optical Coherence Tomography to Evaluate the Internal Nasal Valve

      Coupling Pressure Sensing with Optical Coherence Tomography to Evaluate the Internal Nasal Valve
      Purpose: To evaluate endoscopic long-range optical coherence tomography system combined with a pressure sensor to concurrently measure internal nasal valve cross-sectional area and intraluminal pressure. Methods: A pressure sensor was constructed using an Arduino platform and calibrated using a limiter-controlled vacuum system and industrial absolute pressure gauge. Long-range optical coherence tomography imaging and pressure transduction were performed concurrently in the naris of eight healthy adult subjects during normal respiration and ...
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      Mentions: UC Irvine
    13. UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology

      UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology
      ...tart the developments in pharmacotherapy, devices, and surgical intervention.

      University of California at Irvine Receives a 2020 NIH Grant for $593,557 for In Vivo Imaging and Quantificati...

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    14. Ultrahigh-sensitive optical coherence elastography

      Ultrahigh-sensitive optical coherence elastography
      The phase stability of an optical coherence elastography (OCE) system is the key determining factor for achieving a precise elasticity measurement, and it can be affected by the signal-to-noise ratio (SNR), timing jitters in the signal acquisition process, and fluctuations in the optical path difference (OPD) between the sample and reference arms. In this study, we developed an OCE system based on swept-source optical coherence tomography (SS-OCT) with a common-path ...
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      Mentions: UC Irvine
    15. Optical Coherence Tomography in the Evaluation of the Scalp and Hair: Common Features and Clinical Utility

      Optical Coherence Tomography in the Evaluation of the Scalp and Hair: Common Features and Clinical Utility
      Background and Objective Early diagnosis and treatment of hair loss disorders is vital in providing patients with improved psychological outcomes. Non‐invasive imaging with optical coherence tomography (OCT) may be useful in characterizing and managing alopecia. Despite expanding clinical applications of OCT in dermatology, guidelines demonstrating in vivo features of normal and alopecic scalp images remain scant. This pilot study aims to provide an atlas of OCT findings of healthy ...
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      Mentions: UC Irvine
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  2. About UC Irvine

    UC Irvine

    The University of California at Irvine is a public research university situated in Irvine, California. Founded in 1965, it is the second-youngest University of California campus.   Beckman Laser Institute at the University of California in Irvine. The BLI mission is to serve as the world's leading interdisciplinary center for Biomedical Optics.