1. UC Davis

    0 Comments Leave a Comment

    1-15 of 150 1 2 3 4 5 6 7 8 9 10 »
    1. Mentioned In 150 Articles

    2. UCDavis Receives NIH Grant for Improving Penetration Depth and Spatial Resolution for In Vivo Deep Imaging of Mouse Brain Using 2200nm Optical Coherence Microscopy

      UCDavis Receives NIH Grant for Improving Penetration Depth and Spatial Resolution for In Vivo Deep Imaging of Mouse Brain Using 2200nm Optical Coherence Microscopy
      ...ate gyrus) and pathology at higher resolutions than were previously possible.

      University of California at Davis Receives a 2017 NIH Grant for $78,500 for Improving Penetration Depth and Sp...

      Read Full Article
    3. In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors

      In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors
      The light responses of rod and cone photoreceptors have been studied electrophysiologically for decades, largely with ex vivo approaches that disrupt the photoreceptors subretinal microenvironment. Here we report the use of optical coherence tomography (OCT) to measure light-driven signals of rod photoreceptors in vivo. Visible light stimulation over a 200-fold intensity range caused correlated rod outer segment (OS) elongation and increased light scattering in wild-type mice, but not in mice ...
      Read Full Article
    4. Structural and functional human retinal imaging with a fiber-based visible light OCT ophthalmoscope

      Structural and functional human retinal imaging with a fiber-based visible light OCT ophthalmoscope
      The design of a multi-functional fiber-based Optical Coherence Tomography (OCT) system for human retinal imaging with 2 micron axial resolution in tissue is described. A detailed noise characterization of two supercontinuum light sources with different pulse repetition rates is presented. The higher repetition rate and lower noise source is found to enable a sensitivity of 96 dB with 0.15 mW light power at the cornea and a 98 microsecond ...
      Read Full Article
    5. Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system

      Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system
      We demonstrate OCT angiography (OCTA) and Doppler OCT imaging of the choroid in the eyes of two healthy volunteers and in a geographic atrophy case. We show that visualization of specific choroidal layers requires selection of appropriate OCTA methods. We investigate how imaging speed, B-scan averaging and scanning density influence visualization of various choroidal vessels. We introduce spatial power spectrum analysis of OCT en face angiographic projections as a method ...
      Read Full Article
    6. UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT
      ... laboratory of John S. Werner where AO-OCT instrumentation has been pioneered and conveniently located in the UC Davis Eye Center. One AO-OCT system is available for the candidate's modification and exclusive use. Traini...
      Read Full Article
    7. Photoreceptor disc shedding in the living human eye

      Photoreceptor disc shedding in the living human eye
      Cone photoreceptors undergo a daily cycle of renewal and shedding of membranous discs in their outer segments (OS), the portion responsible for light capture. These physiological processes are fundamental to maintaining photoreceptor health, and their dysfunction is associated with numerous retinal diseases. While both processes have been extensively studied in animal models and postmortem eyes, little is known about them in the living eye, in particular human. In this study ...
      Read Full Article
    8. A First Glimpse into Disc Shedding in the Human Eye

      A First Glimpse into Disc Shedding in the Human Eye
      An elusive biological cycle in the eye the daily disposal and regeneration of the end tips of photoreceptor cells has been captured in images for the first time in a living human eye. Photoreceptors are light-sensitive cells responsible for initiating vision. This glimpse into the inner workings of the eye will help scientists better understand, prevent and manage major eye diseases that affect photoreceptors like age-related macular degeneration and retinitis ...
      Read Full Article
    9. Dynamic contrast optical coherence tomography images transit time and quantifies microvascular plasma volume and flow in the retina and choriocapillaris

      Dynamic contrast optical coherence tomography images transit time and quantifies microvascular plasma volume and flow in the retina and choriocapillaris
      Despite the prevalence of optical imaging techniques to measure hemodynamics in large retinal vessels, quantitative measurements of retinal capillary and choroidal hemodynamics have traditionally been challenging. Here, a new imaging technique called dynamic contrast optical coherence tomography (DyC-OCT) is applied in the rat eye to study microvascular blood flow in individual retinal and choroidal layersin vivo. DyC-OCT is based on imaging the transit of an intravascular tracer dynamically as it ...
      Read Full Article
    10. The University of California at Davis Receives NIH Grant for the Rodent Eye as a Non-Invasive Window for Understanding Cancer Nanotheraputics

      The University of California at Davis Receives NIH Grant for the Rodent Eye as a Non-Invasive Window for Understanding Cancer Nanotheraputics
      ...a-tumoral biodistribution and fate of drugs encapsulated by nanocarrier, and nanodelivery across the BRB. The University of California at Davis Receives a 2016 NIH Grant for $586,386 for The Rodent Eye as a Non-Invasive ...
      Read Full Article
    11. Role of Tractional Forces and Internal Limiting Membrane in Macular Hole Formation: Insights from Intraoperative Optical Coherence Tomography

      Role of Tractional Forces and Internal Limiting Membrane in Macular Hole Formation: Insights from Intraoperative Optical Coherence Tomography
      We report the case of a 69-year-old patient who underwent vitrectomy for vitreomacular traction (VMT) and developed a postoperative macular hole that was observed 1 week after surgery. The hole did not close by in-office fluid-gas exchange alone, but was achieved after repeat surgery with internal limiting membrane (ILM) peeling. Intraoperative OCT (iOCT) images from the first surgery revealed an occult macular hole that formed after VMT release. We discuss ...
      Read Full Article
      Mentions: UC Davis
    12. A Review of Adaptive Optics Optical Coherence Tomography: Technical Advances, Scientific Applications, and the Future

      A Review of Adaptive Optics Optical Coherence Tomography: Technical Advances, Scientific Applications, and the Future
      Purpose : Optical coherence tomography (OCT) has enabled virtual biopsy of the living human retina, revolutionizing both basic retina research and clinical practice over the past 25 years. For most of those years, in parallel, adaptive optics (AO) has been used to improve the transverse resolution of ophthalmoscopes to foster in vivo study of the retina at the microscopic level. Here, we review work done over the last 15 years to ...
      Read Full Article
    13. Lens-based wavefront sensorless adaptive optics swept source OCT

      Lens-based wavefront sensorless adaptive optics swept source OCT
      Optical coherence tomography (OCT) has revolutionized modern ophthalmology, providing depth resolved images of the retinal layers in a system that is suited to a clinical environment. Although the axial resolution of OCT system, which is a function of the light source bandwidth, is sufficient to resolve retinal features at a micrometer scale, the lateral resolution is dependent on the delivery optics and is limited by ocular aberrations. Through the combination ...
      Read Full Article
    14. Phase-Variance Optical Coherence Tomographic Angiography Imaging of Choroidal Perfusion Changes Associated With Acute Posterior Multifocal Placoid Pigment Epitheliopathy

      Phase-Variance Optical Coherence Tomographic Angiography Imaging of Choroidal Perfusion Changes Associated With Acute Posterior Multifocal Placoid Pigment Epitheliopathy
      This case report uses phase-variance optical coherence tomographic angiography to demonstrate transient inner choroidal flow changes associated with acute posterior multifocal placoid pigment epitheliopathy. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is characterized by bilateral multiple placoid white-gray lesions of the posterior pole at the level of the retinal pigment epithelium (RPE) and/or choriocapillaris, which self-resolve with recovery of vision. 1 , 2 The etiology is unknown, but APMPPE has ...
      Read Full Article
    15. Post-Doc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis

      Post-Doc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis
      ...he UC Davis EyePod Small Animal Imaging Laboratory in the Department of Cell Biology and Human Anatomy at the UC Davis Main Campus. The goal of our research is to develop and translate the next generation in vivo cellula...
      Read Full Article
    16. 1-15 of 150 1 2 3 4 5 6 7 8 9 10 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About UC Davis

    UC Davis

    University of California at Davis is a public university located in the city of Davis, California and is one of the ten campuses of the University of California. Vision Science and Advanced Retinal Imaging Laboratory is at the University of California, Davis and is concerned with understanding the functional and structural basis of early stage mechanisms of human vision. Center for Biophotonics, Science and Technology at The University of California at Davis.  The Center for Biophotonics, Science and Technology (CBST) was conceived in response to the NRC recommendations. UC Davis Medical Center is a major research hospital located in Sacramento, California and is the primary teaching hospital of UC Davis School of Medicine. Researchers and specialists at the 577 licensed bed medical center work in over 150 areas of specialty. The UC Davis hospital has been ranked among the top 50 hospitals in the nation in the 2004 survey of US News and World Report. Particularly respected are its programs in heart surgery and ear, nose, and throat treatment. It is also a Level I trauma center for both adults and pediatrics.