1. UC Davis

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    1. Mentioned In 201 Articles

    2. Visible Light Optical Coherence Tomography (OCT) Quantifies Subcellular Contributions to Outer Retinal Band 4

      Visible Light Optical Coherence Tomography (OCT) Quantifies Subcellular Contributions to Outer Retinal Band 4
      Purpose : To use visible light optical coherence tomography (OCT) to investigate subcellular reflectivity contributions to the outermost (4th) of the retinal hyperreflective bands visualized by current clinical near-infrared (NIR) OCT. Methods : Visible light OCT, with 1.0 m axial resolution, was performed in 28 eyes of 19 human subjects (2157 years old) without history of ocular pathology. Two foveal and three extrafoveal hyperreflective zones were consistently depicted within band 4 ...
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    3. Postdoc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Ocular Imaging Laboratory at University of California, Davis

      Postdoc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Ocular Imaging Laboratory at University of California, Davis
      ... laboratory collaborates closely with UC Davis Eye Center Vision Science and Advanced Retinal Imaging (VSRI). UC Davis has a large, active community of ~45 NIH-funded vision scientists with interests ranging from molecul...
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      Mentions: UC Davis
    4. Kilohertz retinal FF-SS-OCT and flood imaging with hardware-based adaptive optics

      Kilohertz retinal FF-SS-OCT and flood imaging with hardware-based adaptive optics
      A retinal imaging system was designed for full-field (FF) swept-source (SS) optical coherence tomography (OCT) with cellular resolution. The system incorporates a real-time adaptive optics (AO) subsystem and a very high-speed CMOS sensor, and is capable of acquiring volumetric images of the retina at rates up to 1 kHz. While digital aberration correction (DAC) is an attractive potential alternative to AO, it has not yet been shown to provide resolution ...
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      Mentions: UC Davis
    5. Visible light OCT improves imaging through a highly scattering retinal pigment epithelial wall

      Visible light OCT improves imaging through a highly scattering retinal pigment epithelial wall
      Here we provide a counter-example to the conventional wisdom in biomedical optics that longer wavelengths aid deeper imaging in tissue. Specifically, we investigate visible light optical coherence tomography of Bruchs membrane (BM) in the non-pathologic eyes of humans and two mouse strains. Surprisingly, we find that shorter visible wavelengths improve the visualization of BM in pigmented eyes, where it is located behind a highly scattering layer of melanosomes in the ...
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      Mentions: UC Davis
    6. Incoherent excess noise spectrally encodes broadband light sources

      Incoherent excess noise spectrally encodes broadband light sources
      Across optics and photonics, excess intensity noise is often considered a liability. Here, we show that excess noise in broadband supercontinuum and superluminescent diode light sources encodes each spectral channel with unique intensity fluctuations, which actually serve a useful purpose. Specifically, we report that excess noise correlations can both characterize the spectral resolution of spectrometers and enable cross-calibration of their wavelengths across a broad bandwidth. Relative to previous methods that ...
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      Mentions: UC Davis
    7. Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University

      Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University
      ...ividual retinal neurons in the living human and murine eyes. The position will involve travel between OSU and UC Davis. Experience: Candidate should have experience in the field of biomedical imaging or optics. Specif...
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    8. Water wavenumber calibration for visible light optical coherence tomography

      Water wavenumber calibration for visible light optical coherence tomography
      Significance : Visible light optical coherence tomography (OCT) is emerging for spectroscopic and ultrahigh resolution imaging, but challenges remain. Depth-dependent dispersion limits retinal image quality and current correction approaches are cumbersome. Inconsistent group refractive indices during image reconstruction also limit reproducibility. Aim: To introduce and evaluate water wavenumber calibration (WWC), which corrects depth-dependent dispersion and provides an accurate depth axis in water. Approach: Enabled by a visible light OCT spectrometer configuration ...
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      Mentions: UC Davis
    9. Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light

      Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light
      Noninvasive, objective measurement of rod function is as significant as that of cone function, and for retinal diseases such as retinitis pigmentosa and age-related macular degeneration, rod function may be a more sensitive biomarker of disease progression and efficacy of treatment than cone function. Functional imaging of single human rod photoreceptors, however, has proven difficult because their small size and rapid functional response pose challenges for the resolution and speed ...
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      Mentions: UC Davis
    10. Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation

      Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation
      OCT Angiography (OCTA) is a widespread tool for depth‐resolved imaging of chorioretinal vasculature with single microvessel resolution. To improve the clinical interpretation of OCTA, the conditions affecting visualization of microvessels must be defined. Here we inject a scattering plasma tracer (Intralipid) during OCTA imaging of the anesthetized rat eye. In the retina, we find that interlaminar (vertical) vessels that connect laminae have one‐fourth to one‐third the OCTA ...
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    11. Factors Affecting Repeatability of Foveal Avascular Zone Measurement Using Optical Coherence Tomography Angiography in Pathologic Eyes

      Factors Affecting Repeatability of Foveal Avascular Zone Measurement Using Optical Coherence Tomography Angiography in Pathologic Eyes
      Purpose: To determine factors that may affect the repeatability of the foveal avascular zone (FAZ) measurement obtained using optical coherence tomography angiography (OCTA) including instrument type, image segmentation, image quality, and fundus pathology. Patients and Methods: This prospective single-center study enrolled 43 subjects (85 eyes) with retinal vasculopathy, macular edema, optic pathology or normal contralateral eye. The macula was imaged twice using Optovue Angiovue and once using Cirrus Angioplex to ...
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    12. Sample Size Requirements of Glaucoma Clinical Trials When Using Combined Optical Coherence Tomography and Visual Field Endpoints

      Sample Size Requirements of Glaucoma Clinical Trials When Using Combined Optical Coherence Tomography and Visual Field Endpoints
      Glaucoma clinical trials using visual field (VF) endpoints currently require large sample sizes because of the slowly-progressive nature of this disease. We sought to examine whether the combined use of VF testing and non-invasive optical coherence tomography (OCT) imaging of the neuroretinal tissue could improve the feasibility of such trials. To examine this, we included 192 eyes of 121 glaucoma participants seen at 5 visits over a 2-year period to ...
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    13. Retinal Vessel Density in Exudative and Non-Exudative Age-Related Macular Degeneration on Optical Coherence Tomography Angiography

      Retinal Vessel Density in Exudative and Non-Exudative Age-Related Macular Degeneration on Optical Coherence Tomography Angiography
      Importance Although the choroid contributes to the pathogenesis of age-related macular degeneration (AMD), the role of retinal perfusion is unclear. Purpose To compare retinal vascular measurements between eyes with non-exudative and exudative AMD using optical coherence tomography angiography (OCT-A). Design Retrospective, cross-sectional study. Methods OCT-A images were analyzed from 310 eyes of 182 patients (mean age 78.88.8) with non-exudative (54.2%) and exudative (45.8%) AMD to measure ...
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      Mentions: UC Davis
    14. 1-15 of 201 1 2 3 4 ... 12 13 14 »
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  2. About UC Davis

    UC Davis

    University of California at Davis is a public university located in the city of Davis, California and is one of the ten campuses of the University of California. Vision Science and Advanced Retinal Imaging Laboratory is at the University of California, Davis and is concerned with understanding the functional and structural basis of early stage mechanisms of human vision. Center for Biophotonics, Science and Technology at The University of California at Davis.  The Center for Biophotonics, Science and Technology (CBST) was conceived in response to the NRC recommendations. UC Davis Medical Center is a major research hospital located in Sacramento, California and is the primary teaching hospital of UC Davis School of Medicine. Researchers and specialists at the 577 licensed bed medical center work in over 150 areas of specialty. The UC Davis hospital has been ranked among the top 50 hospitals in the nation in the 2004 survey of US News and World Report. Particularly respected are its programs in heart surgery and ear, nose, and throat treatment. It is also a Level I trauma center for both adults and pediatrics.