1. UC Davis

    0 Comments Leave a Comment

    1-15 of 156 1 2 3 4 ... 9 10 11 »
    1. Mentioned In 156 Articles

    2. Macular fluid reduces reproducibility of choroidal thickness measurements on enhanced depth optical coherence tomography

      Macular fluid reduces reproducibility of choroidal thickness measurements on enhanced depth optical coherence tomography
      Purpose To determine if different types of retinal fluid in the central macula affect the reproducibility of choroidal thickness (CT) measurements on enhanced depth imaging optical coherence tomography (EDI-OCT) Design retrospective, reliability analysis Methods EDI-OCT images were obtained and the choroidal-scleral junction was analyzed through semi-automated segmentation. CT was measured at the fovea and averaged across the central 3 mm horizontal segment. Demographic data, central macular thickness and type of ...
      Read Full Article
    3. Photoreceptor Layer Thickness Changes During Dark Adaptation Observed With Ultrahigh-Resolution Optical Coherence Tomography

      Photoreceptor Layer Thickness Changes During Dark Adaptation Observed With Ultrahigh-Resolution Optical Coherence Tomography
      Purpose : To examine outer retinal band changes after flash stimulus and subsequent dark adaptation with ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods : Five dark-adapted left eyes of five normal subjects were imaged with 3-m axial-resolution UHR-OCT during 30 minutes of dark adaptation following 96%, 54%, 23%, and 0% full-field and 54% half-field rhodopsin bleach. We identified the ellipsoid zone inner segment/outer segment (EZ[IS/OS]), cone interdigitation zone (CIZ), rod ...
      Read Full Article
    4. The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography

      The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography
      Purpose : Optical coherence tomography's (OCT) third outer retinal band has been attributed to the zone of interdigitation between RPE cells and cone outer segments. The purpose of this paper is to investigate the structure of this band with adaptive optics (AO)-OCT. Methods : Using AO-OCT, images were obtained from two subjects. Axial structure was characterized by measuring band 3 thickness and separation between bands 2 and 3 in segmented ...
      Read Full Article
    5. Intravascular imaging for characterization of coronary atherosclerosis

      Intravascular imaging for characterization of coronary atherosclerosis
      This short review surveys recent developments in coronary intravascular imaging technologies. We present an outline of the applications of intravascular imaging for guidance of percutaneous coronary interventions and imaging of atherosclerosis, along with emerging clinical evidence for use. Imaging of tissue composition is important for understanding the relation between the presence of a lesion and clinical sequelae. We describe the recent innovations to enable imaging of unstable atherosclerotic plaques, focusing ...
      Read Full Article
    6. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?

      Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?
      Optical Coherence Tomography Angiography (OCTA) refers to a powerful class of OCT scanning protocols and algorithms that selectively enhance the imaging of blood vessel lumens, based mainly on the motion and scattering of red blood cells (RBCs). Though OCTA is widely used in clinical and basic science applications for visualization of perfused blood vessels, OCTA is still primarily a qualitative tool. However, more quantitative hemodynamic information would better delineate disease ...
      Read Full Article
    7. UCDavis Receives NIH Grant for Improving Penetration Depth and Spatial Resolution for In Vivo Deep Imaging of Mouse Brain Using 2200nm Optical Coherence Microscopy

      UCDavis Receives NIH Grant for Improving Penetration Depth and Spatial Resolution for In Vivo Deep Imaging of Mouse Brain Using 2200nm Optical Coherence Microscopy
      ...ate gyrus) and pathology at higher resolutions than were previously possible.

      University of California at Davis Receives a 2017 NIH Grant for $78,500 for Improving Penetration Depth and Sp...

      Read Full Article
    8. In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors

      In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors
      The light responses of rod and cone photoreceptors have been studied electrophysiologically for decades, largely with ex vivo approaches that disrupt the photoreceptors subretinal microenvironment. Here we report the use of optical coherence tomography (OCT) to measure light-driven signals of rod photoreceptors in vivo. Visible light stimulation over a 200-fold intensity range caused correlated rod outer segment (OS) elongation and increased light scattering in wild-type mice, but not in mice ...
      Read Full Article
    9. Structural and functional human retinal imaging with a fiber-based visible light OCT ophthalmoscope

      Structural and functional human retinal imaging with a fiber-based visible light OCT ophthalmoscope
      The design of a multi-functional fiber-based Optical Coherence Tomography (OCT) system for human retinal imaging with 2 micron axial resolution in tissue is described. A detailed noise characterization of two supercontinuum light sources with different pulse repetition rates is presented. The higher repetition rate and lower noise source is found to enable a sensitivity of 96 dB with 0.15 mW light power at the cornea and a 98 microsecond ...
      Read Full Article
    10. Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system

      Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system
      We demonstrate OCT angiography (OCTA) and Doppler OCT imaging of the choroid in the eyes of two healthy volunteers and in a geographic atrophy case. We show that visualization of specific choroidal layers requires selection of appropriate OCTA methods. We investigate how imaging speed, B-scan averaging and scanning density influence visualization of various choroidal vessels. We introduce spatial power spectrum analysis of OCT en face angiographic projections as a method ...
      Read Full Article
    11. UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT
      ... laboratory of John S. Werner where AO-OCT instrumentation has been pioneered and conveniently located in the UC Davis Eye Center. One AO-OCT system is available for the candidate's modification and exclusive use. Traini...
      Read Full Article
    12. Photoreceptor disc shedding in the living human eye

      Photoreceptor disc shedding in the living human eye
      Cone photoreceptors undergo a daily cycle of renewal and shedding of membranous discs in their outer segments (OS), the portion responsible for light capture. These physiological processes are fundamental to maintaining photoreceptor health, and their dysfunction is associated with numerous retinal diseases. While both processes have been extensively studied in animal models and postmortem eyes, little is known about them in the living eye, in particular human. In this study ...
      Read Full Article
    13. A First Glimpse into Disc Shedding in the Human Eye

      A First Glimpse into Disc Shedding in the Human Eye
      An elusive biological cycle in the eye the daily disposal and regeneration of the end tips of photoreceptor cells has been captured in images for the first time in a living human eye. Photoreceptors are light-sensitive cells responsible for initiating vision. This glimpse into the inner workings of the eye will help scientists better understand, prevent and manage major eye diseases that affect photoreceptors like age-related macular degeneration and retinitis ...
      Read Full Article
    14. Dynamic contrast optical coherence tomography images transit time and quantifies microvascular plasma volume and flow in the retina and choriocapillaris

      Dynamic contrast optical coherence tomography images transit time and quantifies microvascular plasma volume and flow in the retina and choriocapillaris
      Despite the prevalence of optical imaging techniques to measure hemodynamics in large retinal vessels, quantitative measurements of retinal capillary and choroidal hemodynamics have traditionally been challenging. Here, a new imaging technique called dynamic contrast optical coherence tomography (DyC-OCT) is applied in the rat eye to study microvascular blood flow in individual retinal and choroidal layersin vivo. DyC-OCT is based on imaging the transit of an intravascular tracer dynamically as it ...
      Read Full Article
    15. 1-15 of 156 1 2 3 4 ... 9 10 11 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About UC Davis

    UC Davis

    University of California at Davis is a public university located in the city of Davis, California and is one of the ten campuses of the University of California. Vision Science and Advanced Retinal Imaging Laboratory is at the University of California, Davis and is concerned with understanding the functional and structural basis of early stage mechanisms of human vision. Center for Biophotonics, Science and Technology at The University of California at Davis.  The Center for Biophotonics, Science and Technology (CBST) was conceived in response to the NRC recommendations. UC Davis Medical Center is a major research hospital located in Sacramento, California and is the primary teaching hospital of UC Davis School of Medicine. Researchers and specialists at the 577 licensed bed medical center work in over 150 areas of specialty. The UC Davis hospital has been ranked among the top 50 hospitals in the nation in the 2004 survey of US News and World Report. Particularly respected are its programs in heart surgery and ear, nose, and throat treatment. It is also a Level I trauma center for both adults and pediatrics.