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1. Mentioned In 297 Articles
2. Multiscale correlation of microvascular changes on optical coherence tomography angiography with retinal sensitivity in diabetic retinopathy
  
  Explore LWW Online Sep 15 2021 Ophthalmology
  
  Purpose: To assess global, zonal, and local correlations between vessel density changes measured by optical coherence tomography angiography (OCTA) and retinal sensitivity measured by microperimetry across diabetic retinopathy severity. Methods: Diabetic patients and non-diabetic controls underwent OCTA imaging and microperimetry testing. Pearson's correlation was used to assess associations between average sensitivity and skeletonized vessel density (SVD) or FAZ area centrally. Linear mixed effects modeling was used to assess relationships ...
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  Mentions: Massachusetts Institute of Technology Tufts University
3. Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions
  
  Explore ScienceDirect Aug 2 2021 Ophthalmology
  
  Purpose: Describe the utility of anterior segment optical coherence tomography angiography (AS-OCTA) to assess ocular surface lesions. Methods: Retrospective, case-control study of 10 eyes of 9 patients with malignant lesions and 23 eyes of 22 patients with benign lesions. Lesions included 13 epithelial, 10 pigmented and 10 lymphoid lesions. Graders performed an average of 3 depth and diameter measurements of peri-lesional vessels entering each lesion on AS-OCTA. Statistical models to ...
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  Mentions: Tufts University
4. Macular Vessel Density in Diabetic Retinopathy Patients: How Can We Accurately Measure and What Can It Tell Us?
  
  Explore Medical Journals Publisher Apr 13 2021 Ophthalmology
  
  ...Center, Boston, MA, USA; 2Tufts University School of Medicine, Boston, MA, USA Correspondence: Nadia K Waheed New England Eye Center, Tufts Medical Center, 260 Tremont St., Boston, MA, 02116, USA Tel +1 617-636-4600 Fax ...
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  Mentions: Tufts University
5. Full Thickness Macular Hole Size by Hypertransmission Signal on Spectral-Domain Optical Coherence Tomography
  
  Explore LWW Online Mar 8 2021 Ophthalmology
  
  Purpose: To assess the full thickness macular hole (FTMH) size using the choroidal hypertransmission signal on spectral domain optical coherence tomography (SD-OCT), and to compare this method to the standard aperture measurement of the minimum aperture size at the level of the neurosensory retina. Design: Cross-sectional study of retrospective data. Methods: Eyes with FTMH imaged on SD-OCT were included. Two independent masked graders used the device's built-in caliper tool ...
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  Mentions: Massachusetts Institute of Technology Tufts University
6. Optical coherence tomography angiography distortion correction in widefield montage images
  
  Explore Home Mar 3 2021
  
  Background: Optical coherence tomography (OCT) imaging is inherently susceptible to distortion artifacts due to the natural curvature of the eye. This study proposes a novel model for widefield OCT angiography (OCTA) distortion correction and analyzes the effects of this correction on quantification metrics. Methods: Widefield OCTA images were obtained on normal subjects at five fixation spatial positions. Radial and field distortion correction were applied and images stitched together to form ...
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  Mentions: University of Washington Tufts University
7. OCT-OCTA segmentation: combining structural and blood flow information to segment Bruch's membrane
  
  Explore OSA | OSA Publishing Feb 2 2021 Ophthalmology
  
  In this paper we present a fully automated graph-based segmentation algorithm that jointly uses optical coherence tomography (OCT) and OCT angiography (OCTA) data to segment Bruch's membrane (BM). This is especially valuable in cases where the spatial correlation between BM, which is usually not visible on OCT scans, and the retinal pigment epithelium (RPE), which is often used as a surrogate for segmenting BM, is distorted by pathology. We ...
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  Mentions: Massachusetts General Hospital Tufts University
8. Macular edema after rhegmatogenous retinal detachment repair: risk factors, OCT analysis, and treatment responses
  
  Explore journalretinavitreous.biomedcentral.com Jan 27 2021 Ophthalmology
  
  Purpose: To investigate risk factors, imaging characteristics, and treatment responses of cystoid macular edema (CME) after rhegmatogenous retinal detachment (RRD) repair. Methods: Consecutive, retrospective case-control series of patients who underwent pars plana vitrectomy (PPV) and/or scleral buckling (SB) for RRD, with at least six months of follow-up. Clinical and surgical parameters of patients with and without CME (nCME), based on spectral-domain optical coherence tomography (OCT), were compared. Results: Of ...
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  Mentions: Tufts University UCLA
9. Deliberations of an International Panel of Experts on OCTA Nomenclature of nAMD
  
  Explore Ophthalmology Dec 30 2020 Ophthalmology
  
  A panel of imaging experts was assembled to review neovascular age-related macular degeneration optical coherence tomography angiography descriptors published to date, and test agreement on use of these terms, which was found to be low. Optical coherence tomography angiography (OCTA) has been used to identify and characterize macular neovascularization (MNV) secondary to age-related macular degeneration (AMD). 1-4 Many studies have explored OCTA morphological features of MNV that might serve as ...
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  Mentions: Massachusetts Institute of Technology Medical University of Vienna Tufts University
10. Retinal hemangioblastoma vascular detail elucidated on swept source optical coherence tomography angiography
  
  Explore ScienceDirect Dec 26 2020 Ophthalmology
  
  Purpose To report the distinct vascular pattern of a treatment-nave retinal hemangioblastoma imaged on swept source optical coherence tomography angiography (SS-OCTA). Observations A 33-year-old female with a history of Von Hippel-Lindau disease presented for follow-up of bilateral retinal hemangioblastomas. Ultra-widefield fundus photography of the left eye revealed a small, juxtapapillary lesion. SS-OCTA imaging centered at the lesion identified two distinct vascular foci. Centrally, the lesion was composed of a dense ...
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11. Swept Source Optical Coherence Tomography Angiography in Small Choroidal Melanomas and Choroidal Nevi
  
  Explore LWW Online Dec 16 2020 Ophthalmology
  
  Purpose: To evaluate the use of swept source optical coherence tomography angiography (SS-OCTA) to detect distinct vascular features in small choroidal melanomas and choroidal nevi. Methods: Patients with a choroidal nevus or a treatment-nave choroidal melanoma were imaged with color fundus photography, ultrasound and SS-OCTA (12x12mm). High-risk features including overlying fluid, orange pigment, shaggy photoreceptors, acoustic hollowness, depth 2mm, and basal diameter 5mm were assessed. OCTA vascular markers included: choroidal ...
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  Mentions: Tufts University
12. Efficient and high accuracy 3-D OCT angiography motion correction in pathology
  
  Explore OSA | OSA Publishing Dec 12 2020 Ophthalmology
  
  We describe a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features such as retinal layers as well as transverse angiographic vascular features in a joint optimization. Combined with orthogonal scanning and favorization of kinematically more plausible displacements, subpixel alignment and micrometer-scale distortion correction is achieved in all 3 dimensions. As no specific ...
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  Mentions: Massachusetts Institute of Technology Tufts University University of Erlangen
13. A practical guide to optical coherence tomography angiography interpretation
  
  Explore journalretinavitreous.biomedcentral.com Nov 17 2020 Ophthalmology
  
  Background Optical coherence tomography angiography (OCTA) can image the retinal vasculature in vivo, without the need for contrast dye. This technology has been commercially available since 2014, however, much of its use has been limited to the research setting. Over time, more clinical practices have adopted OCTA imaging. While countless publications detail OCTAs use for the study of retinal microvasculature, few studies outline OCTAs clinical utility. Body This review provides ...
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  Mentions: Tufts University
14. Maximum A Posteriori Signal Recovery for Optical Coherence Tomography Angiography Image Generation and Denoising
  
  Explore arxiv.org Nov 3 2020
  
  Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed over time and used to compute OCTA image data. OCTA data are prone to noise and artifacts caused by variations in flow speed and patientmovement. We propose a novel iterativemaximuma posteriori signal recovery algorithm in order to generate OCTA ...
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  Mentions: Massachusetts Institute of Technology Tufts University University of Erlangen
15. Choroidal nonperfusion on optical coherence tomography angiography in a case of unilateral posterior segment ocular sarcoidosis misdiagnosed as MEWDS
  
  Explore ScienceDirect Sep 29 2020 Ophthalmology
  
  Purpose To report a case of presumed ocular sarcoidosis initially presenting with features of multiple evanescent white dot syndrome (MEWDS) with atypical optical coherence tomography angiography (OCTA) findings. Observations A 23 year-old woman presented with a unilateral central scotoma, photophobia, and decreased visual acuity after a viral illness. Examination of the right eye revealed multiple round white macular spots and stippled granularity at the fovea. Multimodal imaging with fluorescein angiography ...
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  Mentions: Universidade Federal de São Paulo Tufts University
16. Anterior-segment spectral domain optical coherence tomography in epidermolysis bullosa
  
  Explore ScienceDirect Sep 28 2020 Ophthalmology
  
  Purpose Assess epidermolysis bullosa (EB)-related corneal pathology using anterior segment optical coherence tomography (AS-OCT) and correlate imaging with clinical metrics in EB patients versus age-matched controls. Methods EB patients and controls were recruited during an EB conference (July 2018) and at Tufts Medical Center (JuneAugust 2019). Subjects completed a questionnaire, had best corrected visual acuity (BCVA) tested, and underwent AS-OCT scanning. Stromal and epithelial thickness were measured. Depth, length ...
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  Mentions: Tufts University
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