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    1. Mentioned In 281 Articles

    2. Using the Pathophysiology of Dry AMD to Guide Binarization of the Choriocapillaris on OCTA: A Model

      Explore TVST Journal Ophthalmology
      Using the Pathophysiology of Dry AMD to Guide Binarization of the Choriocapillaris on OCTA: A Model
      Especially since the incorporation of swept laser sources, optical coherence tomography angiography (OCTA) has enabled quantification of choriocapillaris perfusion. A critical step in this process is binarization, which makes angiographic images quantifiable in terms of perfusion metrics. It remains challenging to have confidence that choriocapillaris perfusion metrics reflect the reality of pathophysiologic flow, largely because choice of binarization method can result in significantly different perfusion metric outcomes. This commentary discusses ...
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      Mentions: University of Rochester Jay S. Duker Tufts University

    3. The long-term effects of anti-vascular endothelial growth factor therapy on the optical coherence tomography angiographic appearance of neovascularization in age-related macular degeneration

      Explore journalretinavitreous.biomedcentral.com Ophthalmology
      The long-term effects of anti-vascular endothelial growth factor therapy on the optical coherence tomography angiographic appearance of neovascularization in age-related macular degeneration
      Background The short-term effects of anti-vascular endothelial growth factor (anti-VEGF) treatment on macular neovascularization (MNV) morphology is well described, but long-term studies on morphologic changes and correlation of such changes to the type of MNV have not been conducted. This study aims to determine if different types of MNVs in neovascular AMD (nAMD) behave differently with anti-VEGF treatment as visualized on optical coherence tomography angiography (OCTA). Methods Treatment-nave nAMD patients ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Yale University

    4. High-Speed, Ultrahigh-Resolution Spectral-Domain OCT with Extended Imaging Range Using Reference Arm Length Matching

      Explore TVST Journal Ophthalmology
      High-Speed, Ultrahigh-Resolution Spectral-Domain OCT with Extended Imaging Range Using Reference Arm Length Matching
      Purpose : To develop high-speed, extended-range, ultrahigh-resolution spectral-domain optical coherence tomography (UHR SD-OCT) and demonstrate scan protocols for clinical retinal imaging. Methods : A UHR SD-OCT operating at 840-nm with 150-nm bandwidths was developed. The axial imaging range was extended by dynamically matching reference arm length to the retinal contour during acquisition. Two scan protocols were demonstrated for imaging healthy participants and patients with dry age-related macular degeneration. A high-definition raster protocol ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Tufts University

    7. Ultrahigh Resolution Spectral Domain Optical Coherence Tomography for the Assessment of Micro-Structural Changes in Central Serous Chorioretinopathy: A Pilot Study.

      Explore IOVS Journal Ophthalmology
      Ultrahigh Resolution Spectral Domain Optical Coherence Tomography for the Assessment of Micro-Structural Changes in Central Serous Chorioretinopathy: A Pilot Study.
      Purpose : In central serous chorioretinopathy (CSCR), choroidal hyperpermeability associated with retinal pigment epithelium (RPE) impairment causes a leakage of fluid from the choroid into the subretinal space, with potential damage to the photoreceptors. We hypothesize that ultrahigh-resolution spectral domain optical coherence tomography (UHR SD-OCT) will enable more detailed assessment of structural changes in this condition. Methods : Patients in all stages of CSCR (acute, chronic and post-resolution) were imaged using an ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Jay S. Duker

    8. Evaluating the long-term effects of anti-vascular endothelial growth factor therapy on choroidal neovascularization in age-related macular degeneration using optical coherence tomography angiography

      Explore IOVS Journal Ophthalmology
      Evaluating the long-term effects of anti-vascular endothelial growth factor therapy on choroidal neovascularization in age-related macular degeneration using optical coherence tomography angiography
      Purpose : Optical coherence tomography angiography (OCTA) allows for precise, non-invasive monitoring of changes to choroidal neovascularization (CNV) structure over time. The short-term effects of anti-vascular endothelial growth factor (anti-VEGF) treatment on CNV morphology is well described, but long-term studies on morphologic changes and correlation of such to the type of CNV have not been conducted. This study aims to determine if different types of CNVs in neovascular AMD (nAMD) behave ...
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      Mentions: James G. Fujimoto Andre J. Witkin Massachusetts General Hospital

    9. Bringing Deep Learning Models to the Data: An Application in Recognizing Intra-Retinal Fluid on Optical Coherence Tomography (OCT) Images

      Explore IOVS Journal Ophthalmology
      Bringing Deep Learning Models to the Data: An Application in Recognizing Intra-Retinal Fluid on Optical Coherence Tomography (OCT) Images
      ... of Washington was trained using a model to data approach, to identify intraretinal fluid on OCT scans at the New England Eye Center (NEEC). Patients with active exudative age-related macular degeneration(AMD) imaged at ...
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      Mentions: Jay S. Duker University of Washington Tufts University

    10. Ultrahigh-Resolution Optical Coherence Tomography Investigation of Age-Related Changes in the Photoreceptors, Retinal Pigment Epithelium and Bruch’s Membrane

      Explore IOVS Journal Ophthalmology
      Ultrahigh-Resolution Optical Coherence Tomography Investigation of Age-Related Changes in the Photoreceptors, Retinal Pigment Epithelium and Bruch’s Membrane
      Purpose : Aging is the biggest risk factor for age-related macular degeneration (AMD). Previous histological and ultrastructural studies have suggested that photoreceptors (PR), retinal pigment epithelium (RPE), and Bruchs membrane (BM) undergo changes with aging and in AMD. A new high-speed, ultrahigh-resolution optical coherence tomography (UHR OCT) prototype instrument with depth tracking and software motion correction was used to investigate PR/RPE/BM alterations in normal aging and early AMD. Methods ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Tufts University

    11. Concerns about the interpretation of OCT and fundus findings in COVID-19 patients in recent Lancet publication

      Explore Nature Publishing Group Ophthalmology
      Concerns about the interpretation of OCT and fundus findings in COVID-19 patients in recent Lancet publication
      We read with great interest the correspondence in Lancet by Marinho et al. [ 1 ] describing purported retinal manifestations of coronavirus disease (COVID-19). While there is great interest to understand potential ocular complications of COVID-19 during this pandemic, we have some concerns regarding the interpretation of the fundus and optical coherence tomography (OCT) findings. Marinho et al. examined 12 COVID-19 patients (all confirmed by PCR or antibody testing) with typical systemic ...
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      Mentions: Cleveland Clinic Tufts University Srinivas R. Sadda

    12. Analyzing Relative Flow Speeds in Diabetic Retinopathy Using Variable Interscan Time Analysis Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Analyzing Relative Flow Speeds in Diabetic Retinopathy Using Variable Interscan Time Analysis Optical Coherence Tomography Angiography
      ...ds in the microvascular changes associated with DR. Design and Participants: In this cross-sectional study at New England Eye Center, Boston, Massachusetts, thirteen patients of varying severities of DR were enrolled. Me...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Andre J. Witkin

    13. Macular and Peripapillary OCTA Metrics Predict Progression in Diabetic Retinopathy: A Sub-analysis of TIME-2b Study Data

      Explore American Journal of Ophthalmology Ophthalmology
      Macular and Peripapillary OCTA Metrics Predict Progression in Diabetic Retinopathy: A Sub-analysis of TIME-2b Study Data
      Purpose To identify optical coherence tomography angiography (OCTA) derived vessel metrics of the macula and optic nerve head (ONH) that predict diabetic retinopathy (DR) disease progression. Design Secondary analysis of clinical trial data Methods This was a sub-analysis of prospectively collected data from 73 subjects that participated in the TIME-2b Study (Aerpio Pharmaceuticals), a multi-center clinical trial for patients with moderate to severe DR treated with AKB-9778 and followed over ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Optovue

    15. Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography

      Explore Eye and Vision Ophthalmology
      Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography
      Background To examine the baseline morphological characteristics and alterations in intraretinal microvascular abnormalities (IRMAs) in response to anti-vascular endothelial growth factor (anti-VEGF) treatment, documented by optical coherence tomography angiography (OCTA) in diabetic eyes. Methods In this retrospective study, IRMAs were evaluated with multimodal imaging (fundus photography, fluorescein angiography, OCTA) in treatment-nave diabetic eyes before and after anti-VEGF treatment for diabetic macular edema (DME) and/or proliferative diabetic retinopathy (PDR) and ...
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      Mentions: Yale University Andre J. Witkin Jay S. Duker

    16. Wide-field optical coherence tomography angiography for the detection of proliferative diabetic retinopathy

      Explore Home - Springer Ophthalmology
      Wide-field optical coherence tomography angiography for the detection of proliferative diabetic retinopathy
      Purpose To compare the ability of wide-field optical coherence tomography angiography (WF-OCTA) to that of ultra-wide field fluorescein angiography (UWF-FA) and ultra-wide-field color fundus photography (UWF-CP) to detect retinal neovascularization (NV) in eyes with proliferative diabetic retinopathy (PDR). Methods In this cross-sectional study, nave patients with active PDR underwent UWF-FA and UWF-CP using the Optos 200Tx and WF-OCTA with 1212 mm fields of five visual fixations using the PLEX Elite ...
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      Mentions: Case Western Reserve University Tufts University Optos
    17. 1-15 of 281 1 2 3 4 ... 17 18 19 »
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  4. About Tufts University

    Tufts University

    Tufts University is one of the premier universities in the United States. Tufts enjoys a global reputation for academic excellence and for preparing students as leaders in a wide range of professions.

    Tufts University School of Medicine is one of the eight schools that comprise Tufts University.   The New England Eye Center is a local, national and international referral and consultation facility, providing the most current and comprehensive services in tertiary care ophthalmology. It is a complete clinical and technical center for the testing and treatment of all types of eye diseases and visual problems. Our staff ophthalmologists hold teaching appointments at Tufts University School of Medicine. The New England Eye Center is part of Tufts Medical Center, a major academic medical center in downtown Boston, Massachusetts. Tufts Medical Center offers comprehensive inpatient and outpatient care for adults and children.

  5. Related Topics

    1. Photoreceptor Disruption Secondary to Posterior Vitreous Detachment as Visualized Using High-Speed Ultrahigh-Resolution Optical Coherence Tomography
      188 articles also mentioned Jay S. Duker
    2. Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography
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    3. Still evolving, OCT technology has revolutionized diagnostics
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