1. Tsung-Han Tsai

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    1. Mentioned In 36 Articles

    2. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)

      Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)
      ...ce tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos) * Tsung-Han Tsai, MS Affiliations + Department of Electrical Engineering & Computer Science, Research Laboratory...
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    3. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography

      Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography
      Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA). We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA. The maximum depths of architectural changes were measured and compared between the two treatment groups. RFA was ...
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    4. Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)

      Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)
      Background: Radiofrequency ablation (RFA) is an endoscopic technique used to eradicate Barrett's esophagus (BE). However, such ablation can commonly lead to neosquamous epithelium overlying residual BE glands not visible by conventional endoscopy and may evade detection on random biopsy samples.Objective: To demonstrate the capability of endoscopic 3-dimensional optical coherence tomography (3D-OCT) for the identification and characterization of buried glands before and after RFA therapy.Design: Cross-sectional study.Setting ...
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    5. Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography

      Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography
      ...Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography Tsung-Han Tsai, Benjamin Potsaid, Martin F. Kraus, Chao Zhou, Yuankai K. Tao, Joachim Hornegger, and James G. ...
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    6. Changes in the Expression of the Alzheimer's Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction

      Changes in the Expression of the Alzheimer's Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction
      Mutations in the presenilin genes cause the majority of early-onset familial Alzheimer's disease. Recently, presenilin mutations have been identified in patients with dilated cardiomyopathy (DCM), a common cause of heart failure and the most prevalent diagnosis in cardiac transplantation patients. However, the molecular mechanisms, by which presenilin mutations lead to either AD or DCM, are not yet understood. We have employed transgenic Drosophila models and optical coherence tomography imaging ...
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    7. Piezoelectric transducer based miniature catheter for ultrahigh speed endoscopic optical coherence tomography

      Piezoelectric transducer based miniature catheter for ultrahigh speed endoscopic optical coherence tomography
      ...μm axial resolution, 20 μm lateral resolution, and frame rate of 480 frames per second (fps) is demonstrated. Tsung-Han Tsai, Benjamin M. Potsaid, Martin Kraus, Jonathan J. Liu, Chao Zhou, Joachim Hornegger and James G. ...
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    8. Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues

      Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues
      3D tissue imaging methods are expected to improve surgical management of cancer. In this study, we examined the feasibility of two 3D imaging technologies, optical coherence tomography (OCT) and optical coherence microscopy (OCM), to view human breast specimens based on intrinsic optical contrast. Specifically, we imaged 44 ex vivo breast specimens including 34 benign and 10 malignant lesions with an integrated OCT and OCM system developed in our laboratory. The ...
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    9. Features of Sub-Epithelial Glandular Structures on Three-Dimensional Endoscopic Optical Coherence Tomography (3D-EOCT) After Endoscopic Mucosal Ablation

      Features of Sub-Epithelial Glandular Structures on Three-Dimensional Endoscopic Optical Coherence Tomography (3D-EOCT) After Endoscopic Mucosal Ablation
      ...Coherence Tomography (3D-EOCT) After Endoscopic Mucosal Ablation Walter W. Chan, Desmond C. Adler, Chao Zhou, Tsung-Han Tsai, Hsiang-Chieh Lee, Qin Huang, Joseph M. Schmitt, James G. Fujimoto, Hiroshi Mashimo No abstract...
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    10. Integrated optical coherence tomography and optical coherence microscopy imaging of human pathology

      Integrated optical coherence tomography and optical coherence microscopy imaging of human pathology
      Excisional biopsy is the current gold standard for disease diagnosis; however, it requires a relatively long processing time and it may also suffer from unacceptable false negative rates due to sampling errors. Optical coherence tomography (OCT) is a promising imaging technique that provide real-time, high resolution and three-dimensional (3D) images of tissue morphology. Optical coherence microscopy (OCM) is an extension of OCT, combining both the coherence gating and the confocal ...
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    11. 16-30 of 36 « 1 2 3 »
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  2. About Tsung-Han Tsai

    Tsung-Han Tsai

    Tsung-Han Tsai is an R&D engineer at St. Jude Medical, Inc. He was a research assistant at National Taiwan University between 2003 and 2005, working with Professor Chi-Kuang Sun on biomedical imaging studies using higher-harmonic optical microscopy and confocal microscopy. He was a PhD research assistant in Professor James G. Fujimoto’s Laser Medicine and Medical Imaging Group at Massachusetts Institute of Technology. He specializes in frequency swept lasers design, miniaturized imaging catheter design, laser scanning microscopy system development, and optical coherence tomography for biomedical imaging and clinical applications.