1. Tsung-Han Tsai

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    1. Mentioned In 36 Articles

    2. Optical coherence tomography in gastroenterology: a review and future outlook

      Optical coherence tomography in gastroenterology: a review and future outlook
      Optical coherence tomography (OCT) is an imaging technique optically analogous to ultrasound that can generate depth-resolved images with micrometer-scale resolution. Advances in fiber optics and miniaturized actuation technologies allow OCT imaging of the human body and further expand OCT utilization in applications including but not limited to cardiology and gastroenterology. This review article provides an overview of current OCT development and its clinical utility in the gastrointestinal tract, including disease ...
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    3. Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

      Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source
      Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 m field of view and 5 m transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe ...
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    4. Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography

      Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography
      Radiofrequency ablation (RFA) is widely used for the eradication of dysplasia and the treatment of early stage esophageal carcinoma in patients with Barretts esophagus (BE). However, there are several factors, such as variation of BE epithelium (EP) thickness among individual patients and varying RFA catheter-tissue contact, which may compromise RFA efficacy. We used a high-speed optical coherence tomography (OCT) system to identify and monitor changes in the esophageal tissue architecture ...
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    5. Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature

      Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature
      Endoscopic imaging technologies such as confocal laser endomicroscopy (CLE) and narrowband imaging (NBI) have been used to investigate vascular changes as hallmarks of early cancer in the GI tract. However, the limited frame rate and field of view make CLE imaging sensitive to motion artifacts, whereas NBI has limited resolution and visualizes only the surface vascular pattern. Endoscopic optical coherence tomography (OCT) enables high speed volumetric imaging of subsurface features ...
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    6. Ultrahigh speed endoscopic optical coherence tomography for gastroenterology

      Ultrahigh speed endoscopic optical coherence tomography for gastroenterology
      We describe an ultrahigh speed endoscopic swept source optical coherence tomography (OCT) system for clinical gastroenterology using a vertical-cavity surface-emitting laser (VCSEL) and micromotor imaging catheter. The system had a 600 kHz axial scan rate and 8 m axial resolution in tissue. Imaging was performed with a 3.2 mm diameter imaging catheter at 400 frames per second with a 12 m spot size. Three-dimensional OCT (3D-OCT) imaging was performed ...
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    7. Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter

      Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter
      ...peed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter Tsung-Han Tsai ; Osman O. Ahsen ; Hsiang-Chieh Lee ; Kaicheng Liang ; Michael G. Giacomelli ; Benjamin M. Pots...
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    8. Swept source optical coherence microscopy using a 1310 nm VCSEL light source

      Swept source optical coherence microscopy using a 1310 nm VCSEL light source
      We demonstrate high speed, swept source optical coherence microscopy (OCM) using a MEMS tunable vertical cavity surface-emitting laser (VCSEL) light source. The light source had a sweep rate of 280 kHz, providing a bidirectional axial scan rate of 560 kHz. The sweep bandwidth was 117 nm centered at 1310 nm, corresponding to an axial resolution of 13.1 m in air, corresponding to 8.1 m (9.6 m spectrally ...
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    9. Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

      Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology
      ...hao Zhou, Joachim Hornegger, Hiroshi Mashimo, Alex E. Cable, and James G. Fujimoto »View Author Affiliations Tsung-Han Tsai,^1 Benjamin Potsaid,^1,^2 Yuankai K. Tao,^1 Vijaysekhar Jayaraman,^3 James Jiang,^2 Peter J. S....
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    10. Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology

      Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
      ...trahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology Tsung-Han Tsai ; Yuankai K. Tao ; Benjamin M. Potsaid ; Vijaysekhar Jayaraman ; Martin F. Kraus ; Peter J. S. ...
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  2. About Tsung-Han Tsai

    Tsung-Han Tsai

    Tsung-Han Tsai is an R&D engineer at St. Jude Medical, Inc. He was a research assistant at National Taiwan University between 2003 and 2005, working with Professor Chi-Kuang Sun on biomedical imaging studies using higher-harmonic optical microscopy and confocal microscopy. He was a PhD research assistant in Professor James G. Fujimoto’s Laser Medicine and Medical Imaging Group at Massachusetts Institute of Technology. He specializes in frequency swept lasers design, miniaturized imaging catheter design, laser scanning microscopy system development, and optical coherence tomography for biomedical imaging and clinical applications.