1. Tsunekazu Kakuta

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    1. Mentioned In 20 Articles

    2. Impact of coronary plaque morphology assessed by optical coherence tomography on cardiac troponin elevation in patients with non-ST segment elevation acute coronary syndrome

      Impact of coronary plaque morphology assessed by optical coherence tomography on cardiac troponin elevation in patients with non-ST segment elevation acute coronary syndrome
      Objectives This study aimed to use optical coherence tomography (OCT) to study the relationship between plaque morphology prior to percutaneous coronary intervention (PCI) and post-PCI cardiac troponin (cTn) elevations in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). Furthermore, the relationship between these findings and the adverse cardiac events during follow-up was assessed. Background Association between post-PCI cTn elevations and OCT findings in NSTE-ACS patients is unclear. Methods We evaluated ...
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    3. Coronary Plaque Characteristics in Hemodialysis-Dependent Patients as Assessed by Optical Coherence Tomography

      Coronary Plaque Characteristics in Hemodialysis-Dependent Patients as Assessed by Optical Coherence Tomography
      Coronary arteries in patients with chronic kidney disease (CKD) have been shown to exhibit more extensive atherosclerosis and calcium. We aimed to assess characteristics of coronary plaque in hemodialysis (HD)-dependent patients using optical coherence tomography (OCT). This was a multicenter, retrospective study of 124 patients with stable angina who underwent OCT imaging. Sixty-two HD-dependent patients who underwent pre-intervention OCT for coronary artery disease (CAD) were compared 1:1 with ...
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    4. Guidewire shadow artifacts in optical coherence tomography

      Guidewire shadow artifacts in optical coherence tomography
      BACKGROUND: Because of the high resolution made possible by optical coherence tomography (OCT), previously indistinguishable guidewire artifacts are recognized during coronary imaging, and these affect image interpretation. This study aimed to assess the effect of guidewire size and structure on the artifacts produced and to introduce a novel guidewire specifically for OCT imaging that produces fewer artifacts. Elimination or minimization of guidewire artifacts supports optimal OCT imaging. METHODS: Silicon tubes ...
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    5. Serial examinations of right coronary artery directly injured by radiofrequency catheter ablation with optical coherence tomography and intravascular ultrasound

      Serial examinations of right coronary artery directly injured by radiofrequency catheter ablation with optical coherence tomography and intravascular ultrasound
      A 42-year-old man was referred for ablation. The origin of VT was localized close to the right coronary ostium. During ablation, the catheter tip inadvertently fell into a RCA ostium. The patient developed chest discomfort and ST-segment elevation in the inferior leads was observed. Coronary angiography confirmed severe narrowing of the ostial RCA. Stenting was deferred after satisfactory dilatation by a balloon. The patient discharged with eventless clinical course afterward ...
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    6. Plaque morphologies and the clinical prognosis of acute coronary syndrome caused by lesions with intact fibrous cap diagnosed by optical coherence tomography

      Plaque morphologies and the clinical prognosis of acute coronary syndrome caused by lesions with intact fibrous cap diagnosed by optical coherence tomography
      Background Pathological studies have suggested that acute coronary syndrome (ACS) may be caused by culprit lesions with intact fibrous cap (IFC), including plaque erosions. This study sought to evaluate the morphological features and clinical outcomes of patients with ACS caused by lesions with IFC. Methods A total of 318 patients with ACS who underwent optical coherence tomography (OCT) of a culprit lesion were investigated. The culprit lesions were categorized as ...
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    7. Relationship Between Subclinical Cardiac Troponin I Elevation and Culprit Lesion Characteristics Assessed by Optical Coherence Tomography in Patients Undergoing Elective Percutaneous Coronary Intervention

      Relationship Between Subclinical Cardiac Troponin I Elevation and Culprit Lesion Characteristics Assessed by Optical Coherence Tomography in Patients Undergoing Elective Percutaneous Coronary Intervention
      ...f Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan (M.I.). 1. Correspondence to Tsunekazu Kakuta, MD, Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, 11–7, Manabeshin-machi, Tsuch...
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    8. Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome

      Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome
      Pathology studies reported that three most common causes of acute coronary syndrome (ACS) or sudden cardiac death are plaque rupture, plaque erosion and calcified nodules. The morphological and clinical characteristics of the underlying pathology of ACS, especially plaque erosion and calcified nodule, have never been well studied in vivo. Using optical coherence tomography, we found that plaque erosions are the substrate for ACS in 31% of patients and calcified nodules ...
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    9. In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography

      In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography
      Objectives To characterize the morphological features of plaque erosion and calcified nodule in patients with acute coronary syndrome (ACS) by optical coherence tomography (OCT). Background Plaque erosion and calcified nodule have not been systematically investigated in vivo . Methods One hundred and twenty-six patients with ACS who had undergone pre-intervention OCT imaging were included. The culprit lesions were classified as plaque rupture (PR), erosion (OCT-erosion), calcified nodule (OCT-CN), or others using ...
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    10. In vivo detection of lipid-rich plaque by using a 40-MHz intravascular ultrasound: a comparison with optical coherence tomography findings

      In vivo detection of lipid-rich plaque by using a 40-MHz intravascular ultrasound: a comparison with optical coherence tomography findings
      iMAP has recently been introduced as a new tissue characterization method using the 40-MHz intravascular ultrasound (IVUS). However, few data have been published on the comparative findings of other imaging modalities in vivo. We examined 108 matched lesions from 70 patients (35 with stable angina and 35 with acute coronary syndrome) that underwent percutaneous coronary intervention (PCI) using pre-PCI OCT and IVUS. Identification of OCT-derived lipid-rich plaques and thin-cap fibroatheroma ...
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    11. Comparison of Incidence and Time Course of Neoatherosclerosis Between Bare Metal Stents and Drug-Eluting Stents Using Optical Coherence Tomography

      Comparison of Incidence and Time Course of Neoatherosclerosis Between Bare Metal Stents and Drug-Eluting Stents Using Optical Coherence Tomography
      ...ty, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, China , * Tsunekazu Kakuta, MD, PhD Affiliations + Division of Cardiology, Tsuchiura Kyodo Hospital, Ibaraki, Japan , * ...
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    12. Impact of Coronary Plaque Morphology Assessed by Optical Coherence Tomography on Cardiac Troponin Elevation in Patients With Elective Stent Implantation

      Impact of Coronary Plaque Morphology Assessed by Optical Coherence Tomography on Cardiac Troponin Elevation in Patients With Elective Stent Implantation
      ...tment of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan (M.I.). Correspondence to Tsunekazu Kakuta, MD, Department of Cardiology, Tsuchiura Kyodo General Hospital, 11-7, Manabeshin-machi, Tsuc...
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    13. Feature Of The Week 6/26/11: Thin Coronary Artery Walls Covering Plaque Can Lead to Rupture and Death. How Thin is Too Thin?

      Feature Of The Week 6/26/11: Thin Coronary Artery  Walls Covering Plaque Can Lead to Rupture and Death. How Thin is Too Thin?
      The study of rupture-prone plaques or vulnerable plaque is an active area of research around the world that has been buoyed with the power of both research systems and St. Jude Medical's commercially available intravascular OCT system to provide detailed high-resolution in-vivo images of the coronary artery and other arteries. Researchers from Tsuchiura Kyodo Hospital recently published in this area. A summary of their work is give below.Plaque ...
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    14. Assessment of Echo-Attenuated Plaque by Optical Coherence Tomography and its Impact on Post-Procedural Creatine Kinase-Myocardial Band Elevation in Elective Stent Implantation

      Assessment of Echo-Attenuated Plaque by Optical Coherence Tomography and its Impact on Post-Procedural Creatine Kinase-Myocardial Band Elevation in Elective Stent Implantation
      ...scular Medicine, Tokyo Medical and Dental University, Tokyo, Japan * Reprint requests and correspondence: Dr. Tsunekazu Kakuta, Department of Cardiology, Tsuchiura Kyodo Hospital, 11-7, Manabeshin-machi, Tsuchiura, Ibara...
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    15. In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography

      In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography
      Aims The widely accepted threshold of <65 μm for coronary plaque fibrous cap thickness was derived from postmortem studies of ruptured plaques and may not be appropriate for in vivo rupture-prone plaques. We investigated the relationship between fibrous cap thickness and plaque rupture using optical coherence tomography (OCT). Methods and results We studied 266 lesions (103 from patients with acute coronary syndrome and 163 from patients with stable angina) before ...
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    16. Impact of plaque morphology on creatine kinase-MB elevation in patients with elective stent implantation

      Impact of plaque morphology on creatine kinase-MB elevation in patients with elective stent implantation
      Abstract: Backgrounds: The association between percutaneous coronary intervention (PCI) and subsequent myonecrosis has been widely recognized, and worse prognosis has been reported among patients with elevated post-PCI biomarkers. We used optical coherence tomography (OCT) to study the relationship between pre-PCI plaque morphology and post-PCI creatine kinase-MB (CK-MB) elevation.Methods: One hundred and twenty-five patients with normal pre-PCI CK-MB levels underwent OCT examination before nonemergency stent implantation. Patients were divided into ...
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  2. About Tsunekazu Kakuta

    Tsunekazu Kakuta is at Tsuchiura Kyodo General Hospital in Japan.