1. Tsunekazu Kakuta

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    1. Mentioned In 37 Articles

    2. Predictors of Rapid Plaque Progression: An Optical Coherence Tomography Study

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      Predictors of Rapid Plaque Progression: An Optical Coherence Tomography Study
      Objectives This study sought to identify morphological predictors of rapid plaque progression. Background Two patterns of plaque progression have been described: slow linear progression and rapid step-wise progression. The former pattern will cause stable angina when the narrowing reaches a critical threshold, whereas the latter pattern may lead to acute coronary syndromes or sudden cardiac death. Methods Patients who underwent optical coherence tomography (OCT) imaging during the index procedure and ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    3. Spatial Distribution of Vulnerable Plaques: Comprehensive In Vivo Coronary Plaque Mapping

      Explore imaging.onlinejacc.org Cardiology
      Spatial Distribution of Vulnerable Plaques: Comprehensive In Vivo Coronary Plaque Mapping
      Objectives The authors performed a comprehensive analysis on the distribution of coronary plaques with different phenotypes from our 3-vessel optical coherence tomography (OCT) database. Background Previous pathology studies demonstrated that thin-cap fibroatheroma (TCFA) is localized in specific segments of the epicardial coronary arteries. A detailed description of in vivo coronary plaques of various phenotypes has not been reported. Methods OCT images of all 3 coronary arteries in 131 patients were ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    4. Prognostic impact of healed coronary plaque in non-culprit lesions assessed by optical coherence tomography

      Explore atherosclerosis-journal.com Cardiology
      Prognostic impact of healed coronary plaque in non-culprit lesions assessed by optical coherence tomography
      Background and Aims We sought to investigate the characteristics and prognostic impact of healed plaque (HP) detected by optical coherence tomography (OCT) in non-culprit segments in treated vessels. Methods OCT analysis included HP having a different optical intensity with clear demarcation from underlying plaque, thin-cap fibroatheroma (TCFA), and minimal lumen area. Non-culprit lesion (NCL) was defined as a plaque with 90 arc of disease (0.5mm intimal thickness), length 2 ...
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      Mentions: Gary S. Mintz Tsunekazu Kakuta Tetsumin Lee

    5. Circadian variations in pathogenesis of ST-segment elevation myocardial infarction: an optical coherence tomography study

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      Circadian variations in pathogenesis of ST-segment elevation myocardial infarction: an optical coherence tomography study
      Previous studies have reported a circadian variation in the onset of ST-segment elevation myocardial infarction (STEMI). However, underlying mechanisms for the circadian variation have not been fully elucidated. We investigated the relationship between onset of STEMI and the underlying pathology using optical coherence tomography (OCT). Patients with a diagnosis of STEMI were selected from a multicenter OCT registry. Patients were divided into 4 groups based on the estimated time of ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Masamichi Takano

    6. Predictors for layered coronary plaques: an optical coherence tomography study

      Explore Home - Springer Cardiology
      Predictors for layered coronary plaques: an optical coherence tomography study
      Healed coronary plaques, morphologically characterized by a layered pattern, are signatures of previous plaque disruption and healing. Recent optical coherence tomography (OCT) studies showed that layered plaque is associated with vascular vulnerability. However, factors associated with layered plaques have not been studied. The aim of this study was to investigate predictors for layered plaque at the culprit plaques and at non-culprit plaques. Patients with coronary artery disease who underwent pre-intervention ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    7. COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME

      Explore onlinejacc.org Cardiology
      COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME
      Background Recently, three subtypes of calcified plaques at the culprit lesion were reported in patients with acute coronary syndrome (ACS): eruptive calcified nodule, superficial calcific sheet, and calcified protrusion. Methods A total of 157 patients with ACS and calcified plaque at the culprit lesion were selected from our database. Optical coherence tomography (OCT) findings at index procedure and after stent implantation were compared among the three subgroups. Results In the ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Masamichi Takano

    8. Comprehensive In Vivo Coronary Plaque Mapping: A 3-Vessel Optical Coherence Tomography Study

      Explore ScienceDirect Cardiology
      Comprehensive In Vivo Coronary Plaque Mapping: A 3-Vessel Optical Coherence Tomography Study
      Background Previous pathology studies demonstrated that thin-cap fibroatheroma (TCFA) is localized in specific segments of the epicardial coronary arteries. A detailed description of in vivo coronary plaques of various phenotypes has not been reported. Objectives We performed a comprehensive analysis on the distribution of coronary plaques with different phenotypes from our 3-vessel optical coherence tomography (OCT) database. Methods OCT images of all 3 coronary arteries in 131 patients were analyzed ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    9. Comparison of post‐stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome

      Explore Wiley Online Library Cardiology
      Comparison of post‐stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome
      Objectives To compare the postprocedural optical coherence tomography (OCT) findings and in‐hospital outcomes among the three subtypes of calcified plaques: eruptive calcified nodules, superficial calcific sheet, and calcified protrusion. Background Recently, three subtypes of calcified culprit plaques were reported in patients with acute coronary syndrome (ACS). How these subtypes respond to stenting is unknown. Methods ACS patients with calcified plaque at the culprit lesion were selected from our database ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Masamichi Takano

    10. Plaque morphology assessed by optical coherence tomography in the culprit lesions of the first episode of acute myocardial infarction in patients with low low-density lipoprotein cholesterol level

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      Plaque morphology assessed by optical coherence tomography in the culprit lesions of the first episode of acute myocardial infarction in patients with low low-density lipoprotein cholesterol level
      Background There remains a residual risk for acute myocardial infarction (AMI) even with low low-density lipoprotein cholesterol (LDL-C) levels. This study aimed to characterize the culprit lesion morphology of AMI by optical coherence tomography (OCT) in patients with low LDL-C. Methods Four-hundred and nine culprit lesions of 409 patients with their first presentation of AMI imaged by OCT were investigated. OCT analysis included the presence of plaque rupture and thin-capped ...
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      Mentions: Tokyo Medical & Dental University Tsunekazu Kakuta Tetsumin Lee

    11. Primary percutaneous coronary intervention for a left main bifurcation lesion without stenting using excimer laser with optical coherence tomography guidance: a case report

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      Primary percutaneous coronary intervention for a left main bifurcation lesion without stenting using excimer laser with optical coherence tomography guidance: a case report
      Background Optimal strategy for treating bifurcation lesions or lesions with large thrombus in left main disease remains elusive. Excimer laser coronary angioplasty (ELCA) is a therapeutic option for thrombotic lesions in acute coronary syndrome. Case summary A 68-year-old man with chest pain was transferred to our emergency department, and subsequently diagnosed as inferior ST-segment elevation myocardial infarction (STEMI). Emergent coronary angiography revealed a 75% stenosis in the left main trunk ...
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      Mentions: Tsunekazu Kakuta

    12. Optical coherence tomography‐defined plaque vulnerability in relation to functional stenosis severity stratified by fractional flow reserve and quantitative flow ratio

      Explore Wiley Online Library Cardiology
      Optical coherence tomography‐defined plaque vulnerability in relation to functional stenosis severity stratified by fractional flow reserve and quantitative flow ratio
      Objectives We sought to investigate that the quantitative flow ratio (QFR) might be associated with optical coherence tomography (OCT)‐defined plaque vulnerability. Background Both functional stenosis severity and plaque instability are related to adverse clinical outcomes in patients with coronary artery disease. Recent studies have shown an association between physiological stenosis severity and the presence of thin‐cap fibroatheroma (TCFA). Measurement of QFR is a novel method for rapid computational ...
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      Mentions: Tokyo Medical & Dental University Tsunekazu Kakuta Tetsumin Lee

    13. Ventricular Fibrillation During Optical Coherence Tomography/Optical Frequency Domain Imaging　― A Large Single-Center Experience ―

      Explore jstage.jst.go.jp Cardiology
      Ventricular Fibrillation During Optical Coherence Tomography/Optical Frequency Domain Imaging　― A Large Single-Center Experience ―
      Abstract Background: The risks of ventricular fibrillation (Vfib) associated with frequency-domain optical coherence tomography (OCT)/optical frequency domain imaging (OFDI) remain undetermined. Methods and Results: We retrospectively studied the occurrence of Vfib during OCT/OFDI for unselected indications. The frequency of Vfib and patient and procedural characteristics were investigated. A total of 4,467 OCT/OFDI pullback examinations were performed in 1,754 patients (median of 2.0 [2.03 ...
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      Mentions: Kyoto University Graduate School of Medicine Tsunekazu Kakuta Tetsumin Lee

    14. The relation between optical coherence tomography-detected layered pattern and acute side branch occlusion after provisional stenting of coronary bifurcation lesions

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      The relation between optical coherence tomography-detected layered pattern and acute side branch occlusion after provisional stenting of coronary bifurcation lesions
      Background/Purpose. Layered pattern (presumed to be healed plaque after a thrombotic event) can be observed by optical coherence tomography (OCT). We sought to assess the ability of OCT-detected plaque composition to predict acute side branch (SB) occlusion after provisional bifurcation stenting. Methods This is a retrospective observational study using pre-intervention OCT in the main vessel to predict Thrombolysis in Myocardial Infarction (TIMI) flow grade 1 in a SB (diameter ...
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      Mentions: Columbia University Cardiovascular Research Foundation Gary S. Mintz

    15. Optical Coherence Tomography–Defined Plaque Vulnerability in Relation to Functional Stenosis Severity and Microvascular Dysfunction

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      Optical Coherence Tomography–Defined Plaque Vulnerability in Relation to Functional Stenosis Severity and Microvascular Dysfunction
      Objectives This study sought to investigate the relationship of unstable plaque features with physiological lesion severity and microvascular dysfunction . Background The functional severity of epicardial lesions and microvascular dysfunction are both related to adverse clinical outcomes. Methods We investigated 382 de novo intermediate and severe coronary lesions in 340 patients who underwent optical coherence tomography , fractional flow reserve (FFR), and index of microcirculatory resistance (IMR) examinations. Lesions were divided into ...
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      Mentions: Tokyo Medical & Dental University Tsunekazu Kakuta Tetsumin Lee
    17. 1-15 of 37 1 2 3 »
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  4. About Tsunekazu Kakuta

    Tsunekazu Kakuta is at Tsuchiura Kyodo General Hospital in Japan.

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