1. Tsinghua University

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    1. Mentioned In 98 Articles

    2. Ultrahigh resolution spectral-domain optical coherence tomography using the 1000-1600 nm spectral band

      Ultrahigh resolution spectral-domain optical coherence tomography using the 1000-1600 nm spectral band
      Ultrahigh resolution optical coherence tomography (UHR-OCT) can image microscopic features that are not visible with the standard OCT resolution of 5-15 m. In previous studies, high-speed UHR-OCT has been accomplished within the visible (VIS) and near-infrared (NIR-I) spectral ranges, specifically within 550-950 nm. Here, we present a spectral domain UHR-OCT system operating in a short-wavelength infrared (SWIR) range from 1000 to 1600 nm using a supercontinuum light source and an ...
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    3. Pencil-beam scanning catheter for intracoronary optical coherence tomography

      Pencil-beam scanning catheter for intracoronary optical coherence tomography
      Current gradient-index (GRIN) lens based proximal-driven intracoronary optical coherence tomography (ICOCT) probes consist of a spacer and a GRIN lens with large gradient constant. This design provides great flexibility to control beam profiles, but the spacer length should be well controlled to obtain desired beam profiles and thus it sets an obstacle in mass catheter fabrication. Besides, although GRIN lens with large gradient constant can provide tight focus spot, it ...
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    4. OCT Retinal fundus image super-resolution based on a realistic mixed attention GAN (RMA-GAN)

      OCT Retinal fundus image super-resolution based on a realistic mixed attention GAN (RMA-GAN)
      Purpose: Optical coherence tomography (OCT) is widely used to diagnose retinal diseases. However, due to the limited resolution of OCT imaging systems, the quality of fundus images displayed is not satisfactory, which hinders the diagnosis of patients by ophthalmologists. This is an inevitable problem of OCT imaging systems, but few people have given attention to it. We attempt to solve this problem through deep learning methods. Methods: In this paper ...
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    5. Full-range optical coherence refraction tomography

      Full-range optical coherence refraction tomography
      In full-range optical coherence tomography (FROCT), the axial resolution is often superior to the lateral resolution, which is degraded by its signal processing and presents nonuniformity at different imaging depths due to the defocus effect. Optical coherence refraction tomography (OCRT) uses images from multiple angles to computationally reconstruct an image with isotropic resolution, solving the problem of image resolution anisotropy in the sub-millimeter imaging depth range. In this work, we ...
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    6. Optical Coherence Tomography Angiography Predicts Visual Outcomes for Craniopharyngioma in Children by Quantifying Choroidal Capillaries

      Optical Coherence Tomography Angiography Predicts Visual Outcomes for Craniopharyngioma in Children by Quantifying Choroidal Capillaries
      Purpose: To predict the prognosis of craniopharyngioma in children by optical coherence tomography angiography (OCTA). Methods: We evaluated if the relationship between preoperative OCTA of the choroidal capillary density (CCD) and visual outcome continued over long-term visual recovery in 38 patients undergoing craniopharyngioma resection. Patients were evaluated 3 times: 1 week before surgery (Visit1), followed-up at 6-10 weeks (Visit2), and 9-15 months (Visit3) after surgery. Results: In total 38 patients ...
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    7. Microtensile bond strength to sealer-contaminated dentin after using different cleaning protocols

      Microtensile bond strength to sealer-contaminated dentin after using different cleaning protocols
      Background/purpose Sealer residues on dentin may affect bonding to restorative materials. This study aimed to evaluate the bond strength to sealer-contaminated dentin after using different cleaning protocols. Materials and methods Freshly extracted bovine incisors were prepared and exposed the buccal pulp chamber dentin, obtaining segments measuring 5 mm 5 mm with a height of 3 mm. The segments were randomly distributed into 4 groups (n = 7) according to different ...
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    8. Optical coherence tomography-surveilled laser ablation using multifunctional catheter and 355-nm optical pulses

      Optical coherence tomography-surveilled laser ablation using multifunctional catheter and 355-nm optical pulses
      An optical coherence tomography (OCT)-monitored laser ablation system is presented in this study. The laser ablation subsystem is constructed using the third harmonic output of a Nd:YAG laser source operating at a 355-nm optical wavelength with a single pulse energy greater than 160 mJ and a 110 Hz tunable repetition rate. The imaging subsystem is a typical M-mode swept-source OCT system. Moreover, a type of all-fiber multifunctional integrated ...
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    9. The effects of electrical pulses-mediated gold and silver nanoparticles on the optical properties of ex vivo human femoral head tissue with optical coherence tomography

      The effects of electrical pulses-mediated gold and silver nanoparticles on the optical properties of ex vivo human femoral head tissue with optical coherence tomography
      This study aims to monitor and assess the penetration and accumulation of gold nanoparticles (Au NPs) or silver nanoparticles (Ag NPs) (average particle size 40 nm) and the penetration of the Au NPs or Ag NPs assisted by electrical impulses (EP) in human normal femoral head (NFH) and pathological femoral head (PFH) tissues. The results show that optical coherence tomography images can easily distinguish NFH from PFH tissues. The control ...
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    10. Automatic diagnosis of macular diseases from OCT volume based on its two-dimensional feature map and convolutional neural network with attention mechanism.

      Automatic diagnosis of macular diseases from OCT volume based on its two-dimensional feature map and convolutional neural network with attention mechanism.
      Significance: Automatic and accurate classification of three-dimensional (3-D) retinal optical coherence tomography (OCT) images is essential for assisting ophthalmologist in the diagnosis and grading of macular diseases. Therefore, more effective OCT volume classification for automatic recognition of macular diseases is needed. Aim: For OCT volumes in which only OCT volume-level labels are known, OCT volume classifiers based on its global feature and deep learning are designed, validated, and compared with ...
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    11. An imaging analysis and reconstruction method for multiple-micro-electro-mechanical system mirrors-based off-centre scanning optical coherence tomography probe

      An imaging analysis and reconstruction method for multiple-micro-electro-mechanical system mirrors-based off-centre scanning optical coherence tomography probe
      An endoscopic optical coherence tomography (OCT) probe that can perform full circumferential scans using a circular array of six micro-electro-mechanical system (MEMS) mirrors has been developed. Inside the OCT probe, each of the six MEMS mirrors forms an independent scanning unit; circumferential OCT images are acquired by off-centre scanning and combining the image data from the individual multiple scanning units. Here, an imaging analysis and reconstruction (IAR) method is proposed ...
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    12. MDAN-UNet: Multi-Scale and Dual Attention Enhanced Nested U-Net Architecture for Segmentation of Optical Coherence Tomography Images

      MDAN-UNet: Multi-Scale and Dual Attention Enhanced Nested U-Net Architecture for Segmentation of Optical Coherence Tomography Images
      Optical coherence tomography (OCT) is an optical high-resolution imaging technique for ophthalmic diagnosis. In this paper, we take advantages of multi-scale input, multi-scale side output and dual attention mechanism and present an enhanced nested U-Net architecture (MDAN-UNet), a new powerful fully convolutional network for automatic end-to-end segmentation of OCT images. We have evaluated two versions of MDAN-UNet (MDAN-UNet-16 and MDAN-UNet-32) on two publicly available benchmark datasets which are the Duke ...
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    13. Speckle reducing OCT using optical chopper

      Speckle reducing OCT using optical chopper
      Optical coherence tomography (OCT) has been an important and powerful tool for biological research and clinical applications. However, speckle noise significantly degrades the image quality of OCT and has a negative impact on the clinical diagnosis accuracy. In this paper, we propose a novel speckle noise suppression technique which changes the spatial distribution of sample beam using a special optical chopper. Then a series of OCT images with uncorrelated speckle ...
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    14. Machine-Learning Classification of Port Wine Stain With Quantitative Features of Optical Coherence Tomography Image

      Machine-Learning Classification of Port Wine Stain With Quantitative Features of Optical Coherence Tomography Image
      Port wine stain (PWS) is the benign congenital capillary malformation of skin, occurring in 0.3% to 0.5% of the population. In this paper, we build two automated support vector machine (SVM) based classifiers by extracting quantitative features from normal and PWS tissue images recorded by optical coherence tomography (OCT). We use both full feature set and simplified feature set for training. Accuracy of 92.7%, sensitivity of 92 ...
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    15. A Mesh-Based Monte Carlo Study for Investigating Structural and Functional Imaging of Brain Tissue Using Optical Coherence Tomography

      A Mesh-Based Monte Carlo Study for Investigating Structural and Functional Imaging of Brain Tissue Using Optical Coherence Tomography
      Optical coherence tomography (OCT) can obtain high-resolution three-dimensional (3D) structural images of biological tissues, and spectroscopic OCT, which is one of the functional extensions of OCT, can also quantify chromophores of tissues. Due to its unique features, OCT has been increasingly used for brain imaging. To support the development of the simulation and analysis tools on which OCT-based brain imaging depends, a model of mesh-based Monte Carlo for OCT (MMC-OCT ...
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    16. 1-15 of 98 1 2 3 4 5 6 7 »
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  2. About Tsinghua University

    Tsinghua University

    Tsinghua University was established in 1911, originally under the name “Tsinghua Xuetang”. The school was renamed "Tsinghua School" in 1912. The university section was founded in 1925. The name “National Tsinghua University” was adopted in 1928.  The educational philosophy of Tsinghua is to "train students with integrity." Among over 120,000 students who have graduated from Tsinghua since its founding are many outstanding scholars, eminent entrepreneurs and great statesmen remembered and respected by their fellow Chinese citizens. With the motto of “Self-Discipline and Social Commitment” and the spirit of “Actions Speak Louder than Words”, Tsinghua University is dedicated to the well-being of Chinese society and to world development.