1. Tsinghua University

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    1. Mentioned In 70 Articles

    2. Optimized Optical Coherence Tomography Imaging With Hough Transform-Based Fixed-Pattern Noise Reduction

      Optimized Optical Coherence Tomography Imaging With Hough Transform-Based Fixed-Pattern Noise Reduction
      Fixed-pattern noise seriously affects the clinical application of optical coherence tomography (OCT), especially, in the imaging of tumorous tissue. We propose a Hough transform-based fixed-pattern noise reduction (HTFPNR) method to reduce the fixed-pattern noise for optimizing imaging of tumorous tissue with OCT system. Using by the HTFPNR method, we detect and map the outline of fixed-pattern noise in the OCT images, and finally efficiently reduce the fixed-pattern noise by the ...
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    3. Efficient Deep Learning-Based Automated Pathology Identification in Retinal Optical Coherence Tomography Images

      Efficient Deep Learning-Based Automated Pathology Identification in Retinal Optical Coherence Tomography Images
      We present an automatic method based on transfer learning for the identification of dry age-related macular degeneration (AMD) and diabetic macular edema (DME) from retinal optical coherence tomography (OCT) images. The algorithm aims to improve the classification performance of retinal OCT images and shorten the training time. Firstly, we remove the last several layers from the pre-trained Inception V3 model and regard the remaining part as a fixed feature extractor ...
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    4. Simulation of penetration depth of Bessel beams for multifocal optical coherence tomography

      Simulation of penetration depth of Bessel beams for multifocal optical coherence tomography
      Multifocal Bessel beam optical coherence tomography (MBOCT) combines the advantages of Bessel beam OCT and multifocal OCT to increase imaging depth. For MBOCT, the penetration depth of the Bessel beam in highly scattering biological tissue limits the final imaging depth. In this paper, we theoretically analyze the penetration depth of the Bessel beams with different parameters to explore which kind of Bessel beam is more suitable for MBOCT in a ...
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    5. Detection of Latent Fingerprint Hidden Beneath Adhesive Tape by Optical Coherence Tomography

      Detection of Latent Fingerprint Hidden Beneath Adhesive Tape by Optical Coherence Tomography
      Adhesive tape is one type of common item which can be encountered in criminal cases involving rape, murder, kidnapping and explosives. It is often the case that a suspect deposits latent fingerprints on the sticky side of adhesive tape material when tying up victims, manufacturing improvised explosive devices or packaging illegal goods. However, the adhesive tapes found at crime scenes are usually stuck together or attached to a certain substrate ...
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    6. Conjugate transformation for dispersion compensation in optical coherence tomography imaging

      Conjugate transformation for dispersion compensation in optical coherence tomography imaging
      In optical coherence tomography (OCT), the sample dispersion tends to increase the signal width and hence lower down the resolution, resulting in serious image quality degradation, especially for imaging over a large depth range or media with large dispersion coefficient. In this letter, instead of the conventional Fourier transformation for dispersion compensation that can compensate the image only ideally at a certain depth, a novel transformation, as called conjugate transformation ...
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    7. Multifocal spectral-domain optical coherence tomography based on Bessel beam for extended imaging depth

      Multifocal spectral-domain optical coherence tomography based on Bessel beam for extended imaging depth
      To advance the practical application of optical coherence tomography (OCT) in the field of biomedical imaging, the imaging depth must be extended without sacrificing resolution while maintaining sufficient sensitivity. However, there is an inherent trade-off between lateral resolution and depth of field (DOF) in OCT. To address this shortcoming, this article proposes a multifocal Bessel beam spectral-domain optical coherence tomography (MBSDOCT) capable of increasing the DOF with unchanged lateral resolution ...
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    8. Endoscopic optical coherence tomography with a focus-adjustable probe

      Endoscopic optical coherence tomography with a focus-adjustable probe
      We present a focus-adjustable endoscopic probe for optical coherence tomography (OCT), which is able to acquire images with different focal planes and overcome depth-of-focus limitations by image fusing. The use of a two-way shape-memory-alloy spring enables the probe to adjust working distance over 1.5 mm, providing a large scanning range with high resolution and no sensitivity loss. Equipped with a homemade hollow-core ultrasonic motor, the probe is capable of ...
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    9. Fully automated macular pathology detection in retina optical coherence tomography images using sparse coding and dictionary learning

      Fully automated macular pathology detection in retina optical coherence tomography images using sparse coding and dictionary learning
      We propose a framework for automated detection of dry age-related macular degeneration (AMD) and diabetic macular edema (DME) from retina optical coherence tomography (OCT) images, based on sparse coding and dictionary learning. The study aims to improve the classification performance of state-of-the-art methods. First, our method presents a general approach to automatically align and crop retina regions; then it obtains global representations of images by using sparse coding and a ...
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    10. Acoustic-actuated optical coherence angiography

      Acoustic-actuated optical coherence angiography
      Optical coherence tomography (OCT) angiography requires high sensitivity and image penetration for detailed microvascular monitoring. Unfortunately, no effective contrast-medium-enhanced scheme is currently available for imaging improvement. We here propose the simultaneous use of gas-filled microbubbles (MBs) and acoustic actuation to enhance the imaging contrast of OCT angiography. OCT-synchronized acoustic actuation was applied in the presence of MBs, and different moving object tracking angiographic algorithms were tested in in vitro tubing ...
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    11. Feature Of The Week 11/26/2016: Tsinghua University Demonstrates Optical Computing Technique and Achieves High Speed OCT of 10 Mega-A-Scans/Second.

      Feature Of The Week 11/26/2016: Tsinghua University Demonstrates Optical Computing Technique and Achieves High Speed OCT of 10 Mega-A-Scans/Second.
      ...to the performance of current GPUs and CPUs. Professor Ping Xue, Postdoc Xiao Zhang and their colleagues from Tsinghua University in China, have made important progress to solve the problem. They have found a new way to ...
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    12. Optical computing for optical coherence tomography

      Optical computing for optical coherence tomography
      We propose an all-optical Fourier transformation system for real-time massive data processing in high speed optical coherence tomography (OCT). In the so-called optical computing OCT, fast Fourier transformation (FFT) of A-scan signal is optically processed in real time before being detected by photoelectric detector. Therefore, the processing time for interpolation and FFT in traditional Fourier domain OCT can be dramatically eliminated. A processing rate of 10 mega-A-scans/second was experimentally ...
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    13. Characterization of Automotive Paint by Optical Coherence Tomography

      Characterization of Automotive Paint by Optical Coherence Tomography
      Automotive paint is a common trace evidence that plays a significant role in many vehicle-related criminal cases. However, the conventional methods of obtaining tomographic images tend to damage the samples. Optical coherence tomography (OCT) is a novel method to obtain high-resolution, and cross-sectional images of the automotive paints in a non-destructive, and high-speed manner. In this study, OCT was applied to image and analyze the automotive paint, using Scanning Electron ...
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    14. In vivo and in situ imaging of controlled-release dissolving silk microneedles into the skin by optical coherence tomography

      In vivo and in situ imaging of controlled-release dissolving silk microneedles into the skin by optical coherence tomography
      Nowadays, transdermal drug delivery has become a hot topic with regard to delivery. Also, the percutaneous microneedle patch made of water-soluble material makes this technique one step closer to clinical application. The process of the microneedle patch penetrates and dissolves in the animal skin can directly reflect the efficiency of drug delivery. Hence, it is important to reflect the situation of microneedles dissolution and drug release by in vivo and ...
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    15. Ultrahigh-resolution optical coherence tomography at 1.3 μm central wavelength by using a supercontinuum source pumped by noise-like pulses

      Ultrahigh-resolution optical coherence tomography at 1.3 μm central wavelength by using a supercontinuum source pumped by noise-like pulses
      We report on the ultrahigh-resolution optical coherence tomography (OCT) with a novel high-power supercontinuum (SC) light source generated by noise-like pulses from an Yb-doped fiber laser. The SC spectrum is flat with a bandwidth of 420nm centered around ~1.3 m. The light source is successfully employed in a time-domain OCT (TD-OCT), achieving an axial resolution of 2.3 m. High resolution fiber-based spectral-domain OCT (SD-OCT) imaging of bio-tissue was ...
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    16. 3D Automatic Segmentation Method for Retinal Optical Coherence Tomography Volume Data Using Boundary Surface Enhancement

      3D Automatic Segmentation Method for Retinal Optical Coherence Tomography Volume Data Using Boundary Surface Enhancement
      With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need for the development of 3D segmentation methods for processing these data. We present here a novel 3D automatic segmentation method for retinal OCT volume data. Briefly, to segment a boundary surface, two OCT volume datasets are ...
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  2. About Tsinghua University

    Tsinghua University

    Tsinghua University was established in 1911, originally under the name “Tsinghua Xuetang”. The school was renamed "Tsinghua School" in 1912. The university section was founded in 1925. The name “National Tsinghua University” was adopted in 1928.  The educational philosophy of Tsinghua is to "train students with integrity." Among over 120,000 students who have graduated from Tsinghua since its founding are many outstanding scholars, eminent entrepreneurs and great statesmen remembered and respected by their fellow Chinese citizens. With the motto of “Self-Discipline and Social Commitment” and the spirit of “Actions Speak Louder than Words”, Tsinghua University is dedicated to the well-being of Chinese society and to world development.