1. Toyohashi Heart Center

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    1. Mentioned In 34 Articles

    2. In vivo tissue characterization of human atherosclerotic plaques by optical coherence tomography: A directional coronary atherectomy study with histopathologic confirmation

      In vivo tissue characterization of human atherosclerotic plaques by optical coherence tomography: A directional coronary atherectomy study with histopathologic confirmation
      Background The histopathological validation of optical coherence tomography (OCT) in visualizing atherosclerotic plaques has been reported only in ex vivo studies. We sought to evaluate the accuracy of OCT in tissue characterization in vivo . Methods and results A total of 25 patients with stable angina pectoris who underwent directional coronary atherectomy (DCA) were included in the investigation, whereby OCT was performed before and after a single debulking. The debulked region ...
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    3. In-stent restenosis assessed by frequency-domain optical coherence tomography shows smooth coronary arterial healing process in second-generation drug-eluting stents

      In-stent restenosis assessed by frequency-domain optical coherence tomography shows smooth coronary arterial healing process in second-generation drug-eluting stents
      Introduction: The pathophysiology and mechanism of in-stent restenosis (ISR) after implantation of second-generation drug-eluting stents (DESs) are not fully clear. We compared the morphological characteristics of ISR between first- and second-generation DESs using frequency-domain optical coherence tomography (OCT). Methods: Patients who underwent follow-up coronary angiography (CAG) after first(Cypher and Taxus) and second- (Nobori, Promus Element, Resolute Integrity and Xience) generation DES implantations were examined. ISR was defined as lesions ...
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    4. Angiographical Changes Induced by Tiny Coronary Fistula

      Angiographical Changes Induced by Tiny Coronary Fistula
      An 82-year-old female presented with angina pectoris due to mid-right coronary artery (RCA) stenosis. Percutaneous coronary intervention (PCI) was performed with optical coherence tomography (OCT). When OCT was performed with manual coronary flushing to obtain a clearer image, the contrast media seemed to extravasate from the coronary artery, resembling a coronary perforation; however, the patient did not have any chest pain and her vital signs were stable. Coronary angiography (CAG ...
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    5. Differences in Vessel Healing Between Sirolimus- and Everolimus-Eluting Stent Implantation for Bifurcation Lesions: The J-REVERSE Optical Coherence Tomography Substudy

      Differences in Vessel Healing Between Sirolimus- and Everolimus-Eluting Stent Implantation for Bifurcation Lesions: The J-REVERSE Optical Coherence Tomography Substudy
      Background We aimed to clarify the differences in vessel healing after stenting of bifurcation lesions using sirolimus-eluting stents (SESs) or everolimus-eluting stents (EESs). Methods J apanese R egistry Study in Comparison Between Ever olimus-Eluting Stent and S irolimus- E luting Stent for the Bifurcation Lesion (J-REVERSE) is a prospective multicentre registry of 303 bifurcation lesions that were treated with provisional SES or EES with or without final kissing inflation. The ...
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    6. Assessment of vascular response after drug-eluting stents implantation in patients with diabetes mellitus: an optical coherence tomography sub-study of the J-DESsERT

      Assessment of vascular response after drug-eluting stents implantation in patients with diabetes mellitus: an optical coherence tomography sub-study of the J-DESsERT
      ...l, Chiba, Japan Department of Cardiology, Hoshi General Hospital, Koriyama, Japan Department of Cardiology, Toyohashi Heart Center, Toyohashi, Japan Division of Cardiology, Department of Internal Medicine, Memorial He...
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    7. Association of Morphologic Characteristics on Optical Coherence Tomography and Angiographic Progression Patterns of Late Restenosis After Drug-Eluting Stent Implantation

      Association of Morphologic Characteristics on Optical Coherence Tomography and Angiographic Progression Patterns of Late Restenosis After Drug-Eluting Stent Implantation
      Objectives To gain insight into the pathophysiology of late drug-eluting stent (DES) restenosis. Background Restenosis of DES has a different time course from that of bare metal stents. Methods Patients who underwent follow-up coronary angiography (CAG) twice (six to nine months and 18 to 24 months) after DES implantation were examined using optical coherence tomography (OCT). All lesions with target lesion revascularization at first follow-up were excluded. Late catch-up was ...
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    8. Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe

      Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe
      Although lipid lowering therapy by statin and ezetimibe has been reported to provide greater reduction in low-density lipoprotein cholesterol (LDL-C) levels than statin monotherapy, the effect of supplemental therapy on plaque stabilization is yet to be fully elucidated. Cap thickness of fibroatheroma evaluated by Optical coherence tomography (OCT) is a major determinant of vulnerable plaque. The primary objective of this study is to evaluate the effect of ezetimibe in addition ...
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    9. Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography

      Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography
      ...a, MD, * Etsuo Tsuchikane, MD, PhD, * Osamu Katoh, MD, * Takahiko Suzuki, MD, PhD * Department of Cardiology, Toyohashi Heart Center, Toyohashi, Japan Received 8 November 2012 Revised 10 January 2013 Accepted 2 February ...
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    10. Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implantation: an optical coherence tomography study

      Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implantation: an optical coherence tomography study
      Aims Restenosis of drug-eluting stents (DESs) might be different from that of bare metal stent restenosis in diverse ways including mechanisms and time course; however, these have not been fully examined. To gain insight into the mechanisms and time course of DES restenosis, we evaluated the characteristics of restenotic lesions of first generation DES using optical coherence tomography (OCT). Methods and results We compared the morphological characteristics of early in-stent ...
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    11. Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance"

      Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance"
      ... Maoto Habara, MD, 2. Kenya Nasu, MD and 3. Mitsuyasu Terashima, MD 1. Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Japan 1. Hideaki Kaneda, MD 1. Okinaka Memorial Institute for Medical Resea...
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    12. Serial optical coherence tomography imaging of the “black-hole” phenomenon by intravascular ultrasound following sirolimus-eluting stent implantation

      Serial optical coherence tomography imaging of the “black-hole” phenomenon by intravascular ultrasound following sirolimus-eluting stent implantation
      A 60-year-old man underwent sirolimus-eluting stent (SES) implantatoni.  At two months, intravascular ultrasound (IVUS) images showed homogenous echolucent appearance within the stent, recognized as a"black-hole" phenomeon.  Optical coherence tomography (OCT) images of the correspoinding segment demonstrated a layered structure composed of think inner layers with high-intensity signals and outer layers with low-intensity signals.
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    13. Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance

      Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance
      ...T.S.); Okinaka Memorial Institute for Medical Research, Tokyo, Japan (H.K.). Correspondence to Dr Kenya Nasu, Toyohashi Heart Center, 21-1 Gobudori, Oyama-cho, Toyohashi 441–8530, Japan. E-mail Background—Frequency-domai...
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  2. About Toyohashi Heart Center

    Toyohashi Heart Center

    Toyohashi Heart Center is a specialized cardiovascular care center with 24-hour emergency care. Our center comprises two divisions: interventional cardiology and cardiovascular surgery. Interventional Cardiology refers to diagnostics and non-surgical treatments of the heart (coronary artery disease) and surgery programs offer patients a range of surgical operative services. Both divisions are equipped to provide the best possible quality of treatment for each patient.