1. Toshiro Shinke

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    1. Mentioned In 58 Articles

    2. Comparison by Optical Coherence Tomography of Paclitaxel-Eluting Stents With Sirolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure: 6-Month Follow-up

      Comparison by Optical Coherence Tomography of Paclitaxel-Eluting Stents With Sirolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure: 6-Month Follow-up
      Differences between paclitaxel-eluting stents (PES) and sirolimus-eluting stent (SES) in neointimal proliferation under strictly matched conditions remain to be clarified by optical coherence tomography (OCT). Methods and Results: Between May and December 2007, 27 patients were implanted with a PES and a SES, randomized to either the proximal or distal site in a single coronary artery, and underwent follow-up angiography and OCT examination at 6 months. The frequency of vessel ...
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    3. Evaluation of the Peri-strut Low Intensity Area Following Sirolimus- and Paclitaxel-Eluting Stents Implantation: Insights From an Optical Coherence Tomography Study in Humans

      Evaluation of the Peri-strut Low Intensity Area Following Sirolimus- and Paclitaxel-Eluting Stents Implantation: Insights From an Optical Coherence Tomography Study in Humans
      Background: In previous pathological studies, paclitaxel-eluting stents (PES) showed greater fibrin deposition around stent struts, while sirolimus-eluting stent (SES) showed predominance of inflammatory cells with less fibrin deposition than PES. However, there are limited in-vivo data clarifying those qualitative differences in the process of vascular healing after 1st-generation drug-eluting stents (DES) implantation. A recent animal study has shown that peri-strut low intensity area (PLIA) seen in optical coherence tomography (OCT ...
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    4. Factors That Influence Measurements and Accurate Evaluation of Stent Apposition by Optical Coherence Tomography

      Factors That Influence Measurements and Accurate Evaluation of Stent Apposition by Optical Coherence Tomography
      kground: Factors influencing measurements and accurate evaluation of stent apposition by optical coherence tomography (OCT) are not established. Methods and Results: Phantom models of known luminal sizes and lengths were evaluated by OCT under various conditions and measurements were compared with actual values. Stents implanted into phantom models were examined by OCT to validate the measurement point on the stent strut surface for accurate evaluation of stent apposition. Strut thickness ...
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    5. Feature Of The Week 6/14/09: Assessing Sirolimus-Eluting Stent Implantation by Optical Coherence Tomography

      Feature Of The Week 6/14/09: Assessing Sirolimus-Eluting Stent Implantation by Optical Coherence Tomography
      Feature Of The Week 6/14/09: Heart disease is a leading cause of death in the industrialize world. Since the early 1990's when the Palmaz bare medal stent was introduced, stents have continued to play a major role in the treatment of heart disease. The stent market is over $5B and there is intense pressure to improve stent technology from both a healthcare and market share perspective. Optical ...
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    6. Local Determinants of Thrombus Formation Following Sirolimus-Eluting Stent Implantation Assessed by Optical Coherence Tomography

      ...ot increase the risk of major adverse cardiac events. Hiromasa Otake, MD*, Junya Shite, MD*,*, Junya Ako, MD, Toshiro Shinke, MD*, Yusuke Tanino, MD*, Daisuke Ogasawara, MD*, Takahiro Sawada, MD*, Naoki Miyoshi, MD*, Hir...
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    7. Low plasma adiponectin levels are associated with presence of thin-cap fibroatheroma in men with stable coronary artery disease

      Abstract: Background: Previous studies demonstrated the inverse association of adiponectin with coronary artery disease (CAD) especially in men with acute coronary syndrome, however their association with in vivo plaque vulnerability in stable CAD, which may be reflected by the thin-cap fibroatheroma (TCFA) prevalence, remains unknown.Methods: In 50 men with stable CAD, we identified TCFA with multi-vessel examination of combined use of virtual histology intravascular ultrasound (VH-IVUS) and optical coherence ...
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    8. Delayed Neointimalization on Sirolimus-Eluting Stents: 6-Month and 12-Month Follow up by Optical Coherence Tomography

      Background: Sirolimus-eluting stents (SES) have incomplete neointimal coverage at 6-month follow up as determined with optical coherence tomography (OCT). The long-term detailed changes of neointima in SES remains to be clarified. Methods and Results: Serial changes in neointimal coverage of SES from 6 months to 12 months using OCT were examined. Of 21 SES in 13 patients, OCT was used to visualize 2,321 stent struts at 6 months and ...
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    9. Low Plasma Adiponectin Level and High Oxidative Stress are Associated with In Vivo Thin-Cap Fibroatheloma Prevalence in Patients with Stable Coronary Artery Disease

      ...-Cap Fibroatheloma Prevalence in Patients with Stable Coronary Artery Disease Takahiro Sawada^; Junya Shite^; Toshiro Shinke^; Yusuke Tanino^; Daisuke Ogasawara^; Hiroyuki Kawamori^; Hiroki Kato^; Naoki Miyoshi^; Naok...
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    10. Local Determinants and Clinical Significance of Thrombus Formation Following Sirolimus-Eluting Stent Implantation: Insights from Optical Coherence Tomography Analysis

      Angioscopic analyses have shown the presence of subclinical thrombus in sirolimus-eluting stents (SES) is more common than the clinical incidence of stent thrombosis. However, the determinants and long term significance of subclinical thrombus remain unknown. Thirty five patients (44 stents) who received SES underwent 6 months follow-up optical coherence tomography (OCT). Patients were divided into 2 groups according to the presence of thrombus by OCT. Cross-sectional images were analyzed every ...
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    11. Very late thrombosis of sirolimus-eluting stent due to late malapposition: Serial observations with optical coherence tomography

      A 54 years old man underwent directional coronary atherectomy in segment 7 with a partial deep-cut injury. A sirolimus-eluting stent (SES) was implanted at the restenosed post-atherectomy lesion. Six months after SES implantation, intravascular ultrasound (IVUS) examination revealed slight vessel enlargement although there were no malapposed struts. Optical coherence tomography (OCT) revealed partial stent malapposition. Ticlopidine was discontinued 3 months after SES implantation, but aspirin was continued. Twenty-nine months after ...
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    12. Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma

      Aims To evaluate the feasibility of the combined use of virtual histology (VH)-intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for detecting in vivo thin-cap fibroatheroma (TCFA). Methods and results In 56 patients with angina, 126 plaques identified by IVUS findings were analysed using both VH-IVUS and OCT. IVUS-derived TCFA was defined as an abundant necrotic core (>10% of the cross-sectional area) in contact with the lumen (NCCL) and ...
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    13. 46-58 of 58 « 1 2 3 4
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  2. About Toshiro Shinke

    Toshiro Shinke is an MD in cardiology at Department of Internal Medicine, Division of Cardiovascular and Respiratory Medicine, Kobe University Graduate School of Medicine, Japan.