1. Topcon 3D OCT-2000

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    1. Mentioned In 23 Articles

    2. Optical Coherence Tomography Imaging of the Proximal Lacrimal System

      Optical Coherence Tomography Imaging of the Proximal Lacrimal System

      Abstract Introduction: There are currently no routinely used imaging modalities for the proximal lacrimal system. Optical Coherence Tomography (OCT) is a safe and non-invasive method of high resolution cross-sectional imaging of tissue microstructures using infra-red radiation. In this study we investigate whether OCT may be used to image the punctum and proximal canaliculus. Methods: A cohort of healthy subjects with normal ocular anatomy and no symptoms of epiphora were prospectively invited to enrol. Spectral OCT images of the lower punctae were captured with a Topcon 3D Optical Coherence Tomography 2000 machine. Measurements were made of the maximal punctal diameter, canalicular ...

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    3. Intra-operative OCT devices for ophthalmic use: an overview

      Intra-operative OCT devices for ophthalmic use: an overview

      It is feasible to bring the currently most used examination method in ophthalmology, optical coherence tomography (OCT), into ophthalmic surgery to enhance information and control for the surgeon and increase outcome for the patient. In this overview, the currently commercially available OCT devices intending intra-operative OCT imaging are described. Further experience with these systems might not only aid in solving current problems but also open our minds to detect processes so far unknown and help answer questions so far unaddressed.

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    4. Comparative study of macular ganglion cell complex thickness measured by spectral-domain optical coherence tomography in healthy eyes, eyes with preperimetric glaucoma, and eyes with early glaucoma

      Comparative study of macular ganglion cell complex thickness measured by spectral-domain optical coherence tomography in healthy eyes, eyes with preperimetric glaucoma, and eyes with early glaucoma

      Purpose To evaluate the diagnostic accuracy of Topcon 3D spectral-domain optical coherence tomography (SD-OCT) for measuring the macular inner retinal layers and the circumpapillary retinal nerve fiber layer (cpRNFL) in order to detect preperimetric glaucoma. Methods Two hundred four eyes, including 64 healthy eyes, 68 eyes with preperimetric glaucoma, and 72 eyes with early glaucoma were analyzed. Patients had a comprehensive ocular examination including visual field testing and SD-OCT imaging (3D OCT-2000; Topcon Corporation, Tokyo, Japan) in the macular and peripapillary regions. OCT macular scans were segmented into the macular nerve fiber layer (mNFL), ganglion cell layer with the inner ...

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    5. Width of anterior chamber angle determined by OCT, and correlation to refraction and age in a German working population: the MIPH Eye&Health Study

      Width of anterior chamber angle determined by OCT, and correlation to refraction and age in a German working population: the MIPH Eye&Health Study

      Background Optical coherence tomography (OCT) of the anterior segment allows quantitative analysis of the geometry of the chamber angle. We performed bilateral spectral-domain OCT measurements in healthy, emmetropic, hyperopic, and myopic subjects to establish correlations between the width of the angle, the refraction, and intraocular pressure of the test persons. Methods Out of 4,617 eyes (2,309 subjects), those with refractive errors of < −4 or > +3 diopters were identified by objective refraction measurement (KR-8800 Kerato-Refractometer, Topcon Inc., Japan) and examined using the anterior segment mode of a spectral-domain 3D OCT-2000 (Topcon Inc., Japan). Non-contact tonometry was performed (CT-80, Topcon ...

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    6. Direct comparison of spectral-domain and swept-source OCT in the measurement of choroidal thickness in normal eyes

      Direct comparison of spectral-domain and swept-source OCT in the measurement of choroidal thickness in normal eyes

      Objective To compare spectral-domain optic coherence tomography (SD-OCT) and swept-source OCT (SS-OCT) in the study of choroidal thickness (CT) in healthy eyes. Methods Prospective, cross-sectional, single-centre study. 82 healthy eyes of 46 patients were included. In a single session, Topcon 3D-2000 SD-OCT and 1050 nm SS-OCT prototype devices were used to perform OCT scans using a single line protocol. Two masked investigators independently, manually determined 13 CT measurements consisting of one subfoveal (SFCT), and six measurements on either side of the fovea (nasal and temporal) taken every 500 microns apart. The mean CT (MCT) was the mean average of these ...

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    7. Cross-sectional study: Does combining optical coherence tomography measurements using the ‘Random Forest’ decision tree classifier improve the prediction of the presence of perimetric deterioration in glaucoma suspects

      Cross-sectional study: Does combining optical coherence tomography measurements using the ‘Random Forest’ decision tree classifier improve the prediction of the presence of perimetric deterioration in glaucoma suspects
      ...s of 179 participants with open angle glaucoma (OAG) or suspected OAG. Interventions Spectral domain OCT (Topcon 3D OCT-2000) and perimetry (Humphrey Field Analyser, 24-2 or 30-2 SITA standard) measurements were cond...
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    8. Standardised disturbance of the optical coherence tomography signal has varying effects on the scan quality assessment when comparing four devices

      Standardised disturbance of the optical coherence tomography signal has varying effects on the scan quality assessment when comparing four devices

      Introduction Optical coherence tomography (OCT) has become a successful application in ophthalmology. Time-domain OCT (Stratus, Carl Zeiss Meditec) has been overtaken by spectral-domain OCT (SDOCT) which has major advances in imaging speed, sensitivity and image resolution. 1 , 2 Several SDOCT devices are commercially available. In this small study, we assessed the change in subjective image quality and image quality parameter (IQP) provided by four different SDOCT devices using artificial filters simulating optical eye media disturbances. Methods In four healthy subjects, single non-averaged B-scans of the macula were acquired using four commercially available SDOCT systems: 3D OCT-1000 MarkII (Topcon Medical Systems ...

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    9. The ability of macular parameters and circumpapillary retinal nerve fiber layer by three SD-OCT instruments to diagnose highly myopic glaucoma

      The ability of macular parameters and circumpapillary retinal nerve fiber layer by three SD-OCT instruments to diagnose highly myopic glaucoma

      Purpose: To compare the ability of circumpapillary retinal nerve fiber layer (cpRNFL) thickness and macular parameters obtained by three spectral-domain optical coherence tomography (SD-OCT) instruments to detect highly myopic glaucoma. Methods: In this study, 84 glaucomatous eyes, 53 normal eyes with high myopia and 86 normal eyes (not highly myopic) were enrolled. Each participant was imaged using Cirrus, RTVue and 3D OCT to evaluate the average and quadrant cpRNFL thicknesses. The macular retinal nerve fiber layer (mRNFL), ganglion cell layer + inner plexiform layer (GCL/IPL) and mRNFL+GCL/IPL (GCC) thicknesses were analyzed. The areas under the receiver operating characteristic ...

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    10. Preoperative study of the inner segment/outer segment junction of photoreceptors by spectral-domain optical coherence tomography as a prognostic factor in patients with epiretinal membranes

      Preoperative study of the inner segment/outer segment junction of photoreceptors by spectral-domain optical coherence tomography as a prognostic factor in patients with epiretinal membranes

      Objective: To demonstrate whether the preoperative integrity of the inner segment/outer segment (IS/OS) junction of photoreceptors studied by spectral-domain optical coherence tomography (SD-OCT) is a prognostic factor in epiretinal membrane surgery. Methods: We retrospectively studied patients with an idiopathic epiretinal membrane who underwent a 23-gauge vitrectomy to remove this membrane. Best-corrected visual acuity (BCVA) and SD-OCT scans were examined before and 6 months after the surgery. We studied the retinal microstructure, especially the IS/OS junction of the photoreceptors, and evaluated the intergroup differences between patients with an intact layer and those with an irregular or disrupted layer ...

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    11. Correlation of inflammatory and proangiogenic cytokines from undiluted vitreous samples with spectral domain OCT scans, in untreated branch retinal vein occlusion

      Correlation of inflammatory and proangiogenic cytokines from undiluted vitreous samples with spectral domain OCT scans, in untreated branch retinal vein occlusion

      Purpose: To assess the levels of inflammatory and angiogenic cytokines in undiluted vitreous from treatment-naïve patients with macular edema secondary to nonischemic branch retinal vein occlusion (BRVO), with flow cytometric bead array (CBA) and to correlate the results with subjective and multiple spectral-domain optical coherence tomography (SD-OCT) parameters. Methods: A total of 43 eyes from 43 patients (mean age 69.7 years, 23 male) were divided into groups of new, "fresh" (n = 28; mean duration after onset 4.1 months) and older BRVO (n = 15; 11.6 months). Because of macular edema, these patients underwent an intravitreal therapy combining ...

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    12. Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects

      Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects

      Purpose To compare the detection of localized retinal nerve fiber layer (RNFL) defects by two different spectral domain optical coherence tomography (SD-OCT) devices. Methods Eyes of 42 normal control subjects and 48 patients with a localized RNFL defect on red-free fundus photographs were imaged by the Cirrus (Carl Zeiss Meditec, Dublin, CA, USA) and 3D OCT (Topcon, Tokyo, Japan) devices. We compared sensitivities, specificities, and area under the receiver operating characteristic curves (AUCs) of circumpapillary RNFL (cpRNFL) thickness and ganglion cell complex (GCC) parameters between the two devices. Results The devices provided different cpRNFL thickness measurements. The highest sensitivities at ...

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    13. Correlation from Undiluted Vitreous Cytokines of Untreated Central Retinal Vein Occlusion with Spectral Domain Optical Coherence Tomography

      Correlation from Undiluted Vitreous Cytokines of Untreated Central Retinal Vein Occlusion with Spectral Domain Optical Coherence Tomography

      Abstract: Purpose: To correlate inflammatory and proangiogenic key cytokines from undiluted vitreous of treatmentnaïve central retinal vein occlusion (CRVO) patients with SD-OCT parameters. Methods: Thirty-five patients (age 71.1 years, 24 phakic, 30 nonischemic) underwent intravitreal combination therapy, including a single-site 23-gauge core vitrectomy. Twenty-eight samples from patients with idiopathic, non-uveitis floaterectomy served as controls. Interleukin 6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and vascular endothelial growth factor (VEGF-A) levels were correlated with the visual acuity (logMar), category of CRVO (ischemic or nonischemic) and morphologic parameters, such as central macular thickness-CMT, thickness of neurosensory retina- TNeuro, extent of serous retinal ...

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    14. Choroidal Thickness Measurement in Highly Myopic Eyes Using SD-OCT

      Choroidal Thickness Measurement in Highly Myopic Eyes Using SD-OCT

      BACKGROUND AND OBJECTIVE: To measure macular choroidal thickness (CT) using spectral-domain optical coherence tomography (OCT) and to investigate the correlation between CT and age, degree of myopia, and history of macular choroidal neovascularization (CNV). PATIENTS AND METHODS: A cross-sectional study included 187 highly myopic eyes of 187 patients examined between January and December 2010. The choroid was imaged with spectral-domain OCT by changing the reference position from the vitreous to the choroid. CT was measured from the outer border of the hyperreflective line corresponding to the retinal pigment epithelium to the inner scleral border. RESULTS: The mean age was 47 ...

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    15. Comparison of Topcon Optical Coherence Tomography and Ultrasound Pachymetry

      Comparison of Topcon Optical Coherence Tomography and Ultrasound Pachymetry

      Purpose: To establish within-rater repeatability and minimum measurements required for reliable assessment of central corneal thickness (CCT) using Topcon three-dimensional OCT-2000 (Topcon Medical Systems, Oakland, NJ) Fourier-domain optical coherence tomography (FD-OCT) and to test agreement against ultrasound pachymetry (USP). Methods: Twenty participants underwent five scans using FD-OCT followed by five CCT measurements using USP. Each FD-OCT scan produced 12 meridional optical sections, giving 60 sections in total. The FD-OCT CCT was calculated from each section using Topcon FastMap software. Within-rater repeatability was assessed using intraclass correlation coefficient (ICC), within-subject variance ( S w ), and within-subject coefficients of repeatability (COR) and variation ...

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    16. 1-15 of 23 1 2 »
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  2. About Topcon 3D OCT-2000

    3D OCT-2000 is an ophthalmic OCT system made by Topcon Medical Systems targeted at macular and optic nerve imaging.