1. Tom Pfeiffer

    0 Comments Leave a Comment

    1-17 of 17
    1. Mentioned In 17 Articles

    2. Thermo-elastic optical coherence tomography

      Thermo-elastic optical coherence tomography
      The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the ...
      Read Full Article
    3. Feature tracking for automated volume of interest stabilization on 4D-OCT images

      Feature tracking for automated volume of interest stabilization on 4D-OCT images
      A common representation of volumetric medical image data is the triplanar view (TV), in which the surgeon manually selects slices showing the anatomical structure of interest. In addition to common medical imaging such as MRI or computed tomography, recent advances in the field of optical coherence tomography (OCT) have enabled live processing and volumetric rendering of four-dimensional images of the human body. Due to the region of interest undergoing motion ...
      Read Full Article
    4. Analysis of FDML lasers with meter range coherence

      Analysis of FDML lasers with meter range coherence
      FDML lasers provide sweep rates in the MHz range at wide optical bandwidths, making them ideal sources for high speed OCT. Recently, at lower speed, ultralong-range swept-source OCT has been demonstrated using a tunable vertical cavity surface emitting laser (VCSEL) and also using a Vernier-tunable laser. These sources provide relatively high sweep rates and meter range coherence lengths. In order to achieve similar coherence, we developed an extremely well dispersion ...
      Read Full Article
    5. Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy

      Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of coronary artery pathologies and interventions (1) . In contrast to the cross-sectional view, longitudinal sections and 3-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements (2) . We developed Heartbeat OCT, a new OCT method that achieves up to 4,000 frames/s imaging speed for isotropically ...
      Read Full Article
    6. Flexible A-scan rate MHz OCT: computational downscaling by coherent averaging

      Flexible A-scan rate MHz OCT: computational downscaling by coherent averaging
      In order to realize fast OCT-systems with adjustable line rate, we investigate averaging of image data from an FDML based MHz-OCT-system. The line rate can be reduced in software and traded in for increased system sensitivity and image quality. We compare coherent and incoherent averaging to effectively scale down the system speed of a 3.2 MHz FDML OCT system to around 100 kHz in postprocessing. We demonstrate that coherent ...
      Read Full Article
    7. Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography

      Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of the coronary artery pathologies and interventions. In contrast to the cross-sectional view, longitudinal sections and three-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements. We developed Heartbeat OCT, a new OCT method that overcomes these issues. This study aims to demonstrate in vivo Heartbeat OCT ...
      Read Full Article
    8. Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography

      Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography
      Cardiac motion artifacts, non-uniform rotational distortion and undersampling affect the image quality and the diagnostic impact of intravascular optical coherence tomography (IV-OCT). In this study we demonstrate how these limitations of IV-OCT can be addressed by using an imaging system that we called Heartbeat OCT, combining a fast Fourier Domain Mode Locked laser, fast pullback, and a micromotor actuated catheter, designed to examine a coronary vessel in less than one ...
      Read Full Article
    9. Optical coherence tomography guided laser cochleostomy: towards the accuracy on tens of micrometer scale

      Optical coherence tomography guided laser cochleostomy: towards the accuracy on tens of micrometer scale
      Lasers have been proven to be precise tools for bone ablation. Applying no mechanical stress to the patient, they are potentially very suitable for microsurgery on fragile structures such as the inner ear. However, it remains challenging to control the laser-bone ablation without injuring embedded soft tissue. In this work, we demonstrate a closed-loop control of a short-pulsed CO 2 laser to perform laser cochleostomy under the monitoring of an ...
      Read Full Article
    10. High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

      High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s
      We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has ...
      Read Full Article
    11. Feature Of The Week 6/30/13: Ultrafast Intravascular Optical Coherence Tomography Imaging

      Feature Of The Week 6/30/13: Ultrafast Intravascular Optical Coherence Tomography Imaging
      The fastest commercial intravascular optical coherence tomography (OCT) systems acquire 160 frames/second with 500 lines/frame, and the pullback speed is limited to 40 mm∕s. In this situation, the images are under sampled in the pullback direction: Only 12% of the lumen is sampled because the sampling interval of 250 m is much larger than the transverse resolution, which is approximately 30 m. In clinical situations, the cardiac ...
      Read Full Article
    12. Feature Of The Week 6/23/13: Ludwig Maximilian University of Munich Investigates Benefits of Joint Aperture Detection in Ophthalmic MHz OCT

      Feature Of The Week 6/23/13: Ludwig Maximilian University of Munich Investigates Benefits of Joint Aperture Detection in Ophthalmic MHz OCT
      Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ...
      Read Full Article
    13. Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT

      Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
      Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ...
      Read Full Article
    14. 1-17 of 17
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Tom Pfeiffer

    Tom Pfeiffer

    Tom Pfeiffer studied physics at the LMU Munich in Germany. He joined the Emmy Noether / ERC StG group of Robert Huber at the chair for BioMolecular Optics at the LMU as a PhD student in 2011. Recently, he moved with the group of Robert Huber to the Institute of Biomedical imaging to Universität zu Lübeck.