1. Tokyo Medical University

    0 Comments Leave a Comment

    1-15 of 42 1 2 3 »
    1. Mentioned In 42 Articles

    2. Pixel-wise segmentation of severely pathologic retinal pigment epithelium and choroidal stroma using multi-contrast Jones matrix optical coherence tomography

      Pixel-wise segmentation of severely pathologic retinal pigment epithelium and choroidal stroma using multi-contrast Jones matrix optical coherence tomography
      Tissue segmentation of retinal optical coherence tomography (OCT) is widely used in ophthalmic diagnosis. However, its performance in severe pathologic cases is still insufficient. We propose a pixel-wise segmentation method that uses the multi-contrast measurement capability of Jones matrix OCT (JM-OCT). This method is applicable to both normal and pathologic retinal pigment epithelium (RPE) and choroidal stroma. In this method, features, which are sensitive to specific tissues of interest, are ...
      Read Full Article
    3. High contrast and polarization-artifact-free optical coherence tomography by maximum a-posteriori estimation

      High contrast and polarization-artifact-free optical coherence tomography by maximum a-posteriori estimation
      We propose a maximum a-posteriori (MAP) intensity estimator to improve the image contrast of polarization diversity (PD)-OCT imaging to achieve high contrast polarization-artifact-free images. The MAP estimator compensates for the inevitable reduction of signal-to-noise ratio (SNR) in PD-OCT caused by the splitting of power into two polarization detection channels. It also has low noise-offset in low intensity regions such as the vitreous. This method is applied to posterior eye ...
      Read Full Article
    4. Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography

      Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography
      We evaluated intraretinal RPE migration in AMD using multimodal imaging including polarimetric images. Depolarized light images were computed using a PS-SLO. M-DOPU was calculated using multifunctional Jones-matrix OCT. RPE migration was detected in 59 of 155 eyes. Focal similarities could be confirmed among en-face projection images of minimum M-DOPU, depolarized light images, and NIR-AF images.
      Read Full Article
    5. Noise-immune complex correlation for vasculature imaging based on standard and Jones-matrix optical coherence tomography

      Noise-immune complex correlation for vasculature imaging based on standard and Jones-matrix optical coherence tomography
      A new optical coherence angiography (OCA) method, called correlation mapping OCA (cmOCA), is presented by using the SNR-corrected complex correlation. An SNR-correction theory for the complex correlation calculation is presented. The method also integrates a motion-artifact-removal method for the sample motion induced decorrelation artifact. The theory is further extended to compute more reliable correlation by using multi- channel OCT systems, such as Jones-matrix OCT. The high contrast vasculature imaging of ...
      Read Full Article
    6. Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography

      Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography
      Quantitative evaluation of optical properties of choroid and sclera are performed by multifunctional optical coherence tomography. Five normal eyes, five glaucoma eyes and one choroidal atrophy eye are examined. The refractive error was found to be correlated with choroidal birefringence, polarization uniformity, and flow in addition to scleral birefringence among normal eyes. The significant differences were observed between the normal and the glaucoma eyes, as for choroidal polarization uniformity, flow ...
      Read Full Article
    7. Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography

      Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography
      A clinical grade prototype of posterior multifunctional Jones matrix optical coherence tomography (JM-OCT) is presented. This JM-OCT visualized depth-localized birefringence in addition to conventional cumulative phase retardation imaging through local Jones matrix analysis. In addition, it simultaneously provides a sensitivity enhanced scattering OCT, a quantitative polarization uniformity contrast, and OCT-based angiography. The probe beam is at 1- m wavelength band. The measurement speed and the depth-resolution were 100,000 A-lines ...
      Read Full Article
    8. Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography

      Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography
      Background To describe Doppler optical coherence tomography (OCT) imaging of ruptured retinal arterial macroaneurysms (RAMs). Methods Four eyes of four patients with ruptured RAMs were prospectively studied. Vascular imaging was obtained using swept-source Doppler OCT, and compared with indocyanine green angiography images. Results En face projection of Doppler OCT images clearly showed RAMs at the corresponding locations of lesions in the indocyanine green angiography images. In Doppler OCT images, RAMs ...
      Read Full Article
    9. Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography

      Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography
      Purpose. To noninvasively investigate the vascular architecture of polypoidal lesions in polypoidal choroidal vasculopathy (PCV) using Doppler optical coherence tomography (OCT), and to evaluate the clinical usefulness of Doppler OCT for the assessment of therapeutic effects in PCV. Methods. Fifteen eyes of 15 patients with treatment-nave PCV were prospectively studied. Vascular imaging was obtained using 1060-nm swept-source Doppler OCT, and compared with indocyanine green angiography (ICGA) images. The therapeutic effect ...
      Read Full Article
    10. Three-Dimensional Vascular Imaging of Proliferative Diabetic Retinopathy by Doppler Optical Coherence Tomography

      Three-Dimensional Vascular Imaging of Proliferative Diabetic Retinopathy by Doppler Optical Coherence Tomography
      Purpose To evaluate the three-dimensional architecture of neovascularization in proliferative diabetic retinopathy using Doppler optical coherence tomography (OCT). Design Prospective, nonrandomized clinical trial. Methods Seventeen eyes of 14 patients with proliferative diabetic retinopathy were prospectively studied. Prototype Doppler OCT was used to evaluate the three-dimensional vascular architecture at vitreoretinal adhesions. Results Proliferative membranes were detected in all eyes with proliferative diabetic retinopathy by standard OCT images. Doppler OCT images detected ...
      Read Full Article
    11. Findings of secondary corneal amyloidosis with ultrahigh-resolution optical coherence tomography

      Findings of secondary corneal amyloidosis  with ultrahigh-resolution optical coherence  tomography
      ... Community Health Care Organization, Hoshigaoka Medical Center, Hirakata, 2Department of Molecular Pathology, Tokyo Medical University, Tokyo, 3Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto...
      Read Full Article
    12. Simultaneous Investigation of Vascular and Retinal Pigment Epithelial Pathologies of Exudative Macular Diseases by Multi-Functional Optical Coherence Tomography

      Simultaneous Investigation of Vascular and Retinal Pigment Epithelial Pathologies of Exudative Macular Diseases by Multi-Functional Optical Coherence Tomography
      ...uno5,* 1. ^1Univ. of Tsukuba, Tennoudai, Tsukuba, 305-8571, Japan 2. ^2Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, Ami, Ibaraki, Japan 3. ^3Department of Electrical and Co...
      Read Full Article
    13. Scleral birefringence as measured by polarization-sensitive optical coherence tomography and ocular biometric parameters of human eyes in vivo

      Scleral birefringence as measured by polarization-sensitive optical coherence tomography and ocular biometric parameters of human eyes in vivo
      ...^1Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, Japan ^2Department of Ophthalmology, Tokyo Medical University Ibaraki Medical Center, Ami, Ibaraki, Japan ^3Department of Ophthalmology, Faculty ...
      Read Full Article
    14. Non-invasive assessment of corneal crosslinking changes using polarization sensitive optical coherence tomography

      Non-invasive assessment of corneal crosslinking changes using polarization sensitive optical coherence tomography
      Collagen crosslinking (CXL) has shown promising results in the prevention of the progression of keratoconus and corneal ectasia. However, techniques for in vivo and in situ assessment of the treatment are limited. In this study, ex vivo porcine eyes were treated with a chemical CXL agent (glutaraldehyde), during which polarization sensitive optical coherence tomography (PS-OCT) recordings were acquired simultaneously to assess the sensitivity of the technique to assess changes in ...
      Read Full Article
    15. 1-15 of 42 1 2 3 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Tokyo Medical University

    Tokyo Medical University

    Tokyo Medical University is one of the pre-war-established medical schools in Japan. According as the nation’s policy for medical education, this private university has 6-year medical school that offers preclinical and clinical studies to confer bachelor's degree or graduate degree with which medical students can be qualified for the national exam for medical license. TMU also has its postgraduate school (“graduate school”, or daigakuin, in Japanese term) which offers Ph.D.