1. Tokyo Medical & Dental University

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    1. Mentioned In 111 Articles

    2. In vitro and clinical evaluation of optical coherence tomography for the detection of subgingival calculus and root cementum

      In vitro and clinical evaluation of optical coherence tomography for the detection of subgingival calculus and root cementum
      This study evaluated the effectiveness of swept-source optical coherence tomography (ss-OCT) for detecting calculus and root cementum during periodontal therapy. Optical coherence tomography (OCT) images were taken before and after removal of subgingival calculus from extracted teeth and compared with non-decalcified histological sections. Porcine gingival sheets of various thicknesses were applied to the root surfaces of extracted teeth with calculus and OCT images were taken. OCT images were also taken ...
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    3. Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture A 3-Vessel Optical Coherence Tomography Study

      Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture A 3-Vessel Optical Coherence Tomography Study
      Importance Patients with culprit plaque rupture are known to have pancoronary plaque vulnerability. However, the characteristics of nonculprit plaques in patients with acute coronary syndromes caused by plaque erosion are unknown. Objective To investigate the nonculprit plaque phenotype in patients with acute coronary syndrome according to culprit plaque pathology (erosion vs rupture) by 3-vessel optical coherence tomography imaging. Design, Setting, and Participants In this observational cohort study, between August 2010 ...
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    4. Swept-source optical coherence tomographic findings in eyes with metastatic choroidal tumor

      Swept-source optical coherence tomographic findings in eyes with metastatic choroidal tumor
      Purpose To report the swept-source optical coherence tomographic (OCT) findings in two eyes with choroidal metastases. Observations Two patients with choroidal metastasis were studied. The metastasis was from a breast cancer in Case 1 and from a lung cancer in Case 2. In Case 1, swept-source OCT showed a highly reflective solid tumor with low optical reflective tissues that had replaced the choroidal tissue. Swept-source OCT was able to image ...
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    5. Effect of drug-coated balloon on stent restenosis, neointimal proliferation, and coronary dissection: an optical coherence tomography analysis

      Effect of drug-coated balloon on stent restenosis, neointimal proliferation, and coronary dissection: an optical coherence tomography analysis
      Aim: The aim of this study was to assess the acute and mid-term effects of drug-coated balloon (DCB) in terms of the healing process of non-flow-limiting dissections and changes in the neointimal area after DCB treatment using frequency domain optical coherence tomography (FD-OCT). Patients and methods: Thirty-six consecutive patients with in-stent restenosis pretreated with a scoring balloon were evaluated (19 and 17 patients with and without a DCB, respectively). FD-OCT ...
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    6. Posterior Staphylomas in Pathologic Myopia Imaged by Widefield Optical Coherence Tomography

      Posterior Staphylomas in Pathologic Myopia Imaged by Widefield Optical Coherence Tomography
      Purpose : To examine posterior staphylomas by widefield optical coherence tomography (WF-OCT) and three-dimensional magnetic resonance imaging (3D-MRI). Methods : Highly myopic patients (myopic refractive error 8.0 diopters or axial length 26.5 mm) who had previously undergone orbital 3D-MRI were examined by WF-OCT. Results : The study included 100 eyes of 57 patients with a mean age of 67.9 10.7 years (range, 4485 years) and mean axial length of ...
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    7. Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule

      Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule
      Purpose : To investigate structural features of the posterior episclera and Tenon's capsule in patients with high myopia. Methods : This hospital-based observational study included highly myopic eyes (myopic refractive error 8 diopters or axial length 26.5 mm) in which the posterior sclera in its full thickness could be visualized on swept-source optical coherence tomography (OCT) images in all 12 radial scans centered on the fovea. We assessed the posterior ...
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    8. Resolution characteristics of optical coherence tomography for dental use

      Resolution characteristics of optical coherence tomography for dental use
      OBJECTIVES: The purpose of this study was to clarify resolution characteristics of optical coherence tomography (OCT) for dental use. METHODS: Two types of swept-source OCT machines (SS-OCTs) were employed in this study. To clarify their resolution characteristics, we newly developed a glass chart device with a ladder pattern of wavelengths, which ranged from (4 x 2) m to (1024 x 2) m, as well as a star-target pattern, a grid ...
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    9. Three-Dimensional Analysis of Enamel Crack Behavior Using Optical Coherence Tomography

      Three-Dimensional Analysis of Enamel Crack Behavior Using Optical Coherence Tomography
      The aim of this study was to nondestructively analyze enamel crack behavior on different areas of teeth using 3D swept source-optical coherence tomography (SS-OCT). Ten freshly extracted human teeth of each type on each arch ( n = 80 teeth) were inspected for enamel crack patterns on functional, contact and nonfunctional, or noncontact areas using 3D SS-OCT. The predominant crack pattern for each location on each specimen was noted and analyzed. The ...
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    10. Optical analysis of enamel and dentin caries in relation to mineral density using swept-source optical coherence tomography

      Optical analysis of enamel and dentin caries in relation to mineral density using swept-source optical coherence tomography
      The aim of this study was to evaluate the signal intensity and signal attenuation of swept source optical coherence tomography (SS-OCT) for dental caries in relation to the variation of mineral density. SS-OCT observation was performed on the enamel and dentin artificial demineralization and on natural caries. The artificial caries model on enamel and dentin surfaces was created using Streptococcus mutans biofilms incubated in an oral biofilm reactor. The lesions ...
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    11. The effectiveness of optical coherence tomography for evaluating peri-implant tissue: A pilot study

      The effectiveness of optical coherence tomography for evaluating peri-implant tissue: A pilot study
      Purpose Optical coherence tomography (OCT) has been investigated as a novel diagnostic imaging tool. The utilisation of this equipment has been evaluated through several studies in the field of dentistry. The aim of this preliminary study was to determine through basic experiments the effectiveness of OCT in implant dentistry. Materials and Methods To assess detection ability, we captured OCT images of implants in each of the following situations: (1) implants ...
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    12. PERIPAPILLARY ARTERIAL RING OF ZINN-HALLER IN HIGHLY MYOPIC EYES AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      PERIPAPILLARY ARTERIAL RING OF ZINN-HALLER IN HIGHLY MYOPIC EYES AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To visualize the arterial circle of Zinn-Haller (ZHAC) in highly myopic patients by using OCT-A. Methods: Two hundred and fifty-three eyes of 146 consecutive patients with axial length =26.5 mm who underwent OCT-A centered onto the optic disk were studied. Results: Arterial circle of Zinn-Haller was detectable on OCT-A images within the area of the parapapillary myopic conus in 26 (10%) of 253 eyes. The ZHAC was annular ...
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    13. Impact of optical coherence tomography- and coronary angioscopy-assessed neointimal tissue characteristics on occurrence of periprocedural myonecrosis in patients with in-stent restenosis

      Impact of optical coherence tomography- and coronary angioscopy-assessed neointimal tissue characteristics on occurrence of periprocedural myonecrosis in patients with in-stent restenosis
      Several characteristics of neointimal tissues, including neoatherosclerotic progression, have been reported in lesions with in-stent restenosis (ISR). However, the effects of these characteristics on outcomes after percutaneous coronary intervention (PCI) for ISR lesions remain unclear. We assessed the relationships between neointimal tissue characteristics and the occurrence of periprocedural myonecrosis (PMN) after PCI in ISR lesions. We investigated 72 ISR lesions in 72 patients with stable angina pectoris (SAP) who underwent ...
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    14. Assessment of bacterial demineralization around composite restorations using swept-source optical coherence tomography (SS-OCT)

      Assessment of bacterial demineralization around composite restorations using swept-source optical coherence tomography (SS-OCT)
      Objective To observe the bacterial demineralization of the enamel and dentin around composite restorations bonded with one-step and two-step self-etch adhesive systems using swept-source optical coherence tomography (SS-OCT). Methods Forty class V cavities (2.5-mm surface diameter, 2.0-mm maximum depth) were prepared on cervical areas of 20 human molars. The specimens were either treated with one-step adhesive (Clearfil Tri-S Bond ND Quick; TS) or two-step adhesive (Clearfil SE Bond ...
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  2. About Tokyo Medical & Dental University

    Tokyo Medical & Dental University

    Tokyo Medical and Dental University is unique among medical and dental universities in Japan in that we have four divisions dedicated to graduate education and research: Medical and Dental Sciences, Health Care Sciences, the Biomedical Sciences Education Division, and the Biomedical Sciences Research Division. TMDU comprises four faculties (Medicine, Dentistry, Health Care Sciences and Oral Health Care Sciences), an undergraduate College of Liberal Arts and Sciences, two research institutes (the Institute of Biomaterials and Bioengineering and the Medical Research Institute), a university hospital attached to the Faculty of Medicine, a university hospital attached to the Faculty of Dentistry, and a dental technologist school.