1. Tin Aung

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    1. Mentioned In 95 Articles

    2. OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head

      OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head
      ... Devalla Sripad, Hung Pham Tan, Zhang Liang, Aung Tun Tin, Wang Xiaofei, Perera Shamira, Schmetterer Leopold, Aung Tin, and Boote Craig, “Deshadowgan: a deep learning approach to remove shadows from optical coherence tom...
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    3. Utilisation of poor-quality optical coherence tomography scans: adjustment algorithm from the Singapore Epidemiology of Eye Diseases (SEED) study

      Utilisation of poor-quality optical coherence tomography scans: adjustment algorithm from the Singapore Epidemiology of Eye Diseases (SEED) study
      Purpose To evaluate the effect of signal strength (SS) on optical coherence tomography (OCT) parameters, and devise an algorithm to adjust the effect, when acceptable SS cannot be obtained. Methods 5085 individuals (9582 eyes), aged 40 years from the Singapore Epidemiology of Eye Diseases population-based study were included. Everyone underwent a standardised ocular examination and imaging with Cirrus HD-OCT. Effect of SS was evaluated using multiple structural breaks linear mixed-effect ...
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    4. Focal Structure-Function Relationships in Primary Open-Angle Glaucoma Using OCT and OCT-A Measurements

      Focal Structure-Function Relationships in Primary Open-Angle Glaucoma Using OCT and OCT-A Measurements
      Purpose: To evaluate the focal structure-function associations among visual field (VF) loss, optical coherence tomography angiography (OCT-A) vascular measurements, and optical coherence tomography (OCT) structural measurements in glaucoma. Methods: In this cross-sectional study, subjects underwent standard automated perimetry, OCT-based nerve fiber thickness measurements, and OCT-A imaging. Mappings of focal VF test locations with OCT and OCT-A measurements were defined using anatomically adjusted nerve fiber trajectories and were studied using multivariate ...
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    5. Longitudinal assessment of optic nerve head changes using optical coherence tomography in a primate microbead model of ocular hypertension

      Longitudinal assessment of optic nerve head changes using optical coherence tomography in a primate microbead model of ocular hypertension
      In humans, the longitudinal characterisation of early optic nerve head (ONH) damage in ocular hypertension (OHT) is difficult as patients with glaucoma usually have structural ONH damage at the time of diagnosis. Previous studies assessed glaucomatous ONH cupping by measuring the anterior lamina cribrosa depth (LCD) and minimal rim width (MRW) using optical coherence tomography (OCT). In this study, we induced OHT by repeated intracameral microbead injections in 16 cynomolgus ...
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    6. Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study

      Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study
      Precis: Angle closure worsens with pharmacological dilatation in about 50.0% of the subjects diagnosed as primary angle closure suspects. Purpose: To evaluate the changes in angle configuration with swept source anterior segment optical coherence tomography before and after pharmacological pupil dilatation in untreated primary angle closure suspects. Patients Methods: 106 subjects over the age of 50 years and diagnosed as primary angle closure suspects were included in this cross-sectional ...
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    7. Evaluation of meridional scans for angle closure assessment with anterior segment swept-source optical coherence tomography

      Evaluation of meridional scans for angle closure assessment with anterior segment swept-source optical coherence tomography
      Background/aims As swept-source optical coherence tomography (SS-OCT) simultaneously obtains 128 meridional scans, it is important to identify which scans are playing the main role in classifying gonioscopic angle closure to simplify the analysis. We aimed to evaluate the diagnostic performance of every meridional scan in its ability to detect gonioscopic angle closure. Methods Observational study with 2027 phakic subjects consecutively recruited from a community polyclinic. Gonioscopy and SS-OCT were ...
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    8. Towards Label-Free 3D Segmentation of Optical Coherence Tomography Images of the Optic Nerve Head Using Deep Learning

      Towards Label-Free 3D Segmentation of Optical Coherence Tomography Images of the Optic Nerve Head Using Deep Learning
      Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep learning (DL) techniques have been recently proposed for the automated extraction (segmentation) and quantification of these morphological changes, the device-specific nature and the difficulty in preparing manual segmentations (training data) limit their clinical ...
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    9. NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies

      NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies
      ...ecord in translational research excellence, which supports Singapore's vibrant research ecosystem.” Professor Aung Tin, Executive Director, Singapore Eye Research Institute, said, “We hope that this new lab between SNEC-...
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    10. Anterior Segment Optical Coherence Tomography: Is There a Clinical Role in the Management of Primary Angle Closure Disease?

      Anterior Segment Optical Coherence Tomography: Is There a Clinical Role in the Management of Primary Angle Closure Disease?
      Primary angle closure disease (PACD) covers a spectrum that includes primary angle closure suspect, primary angle closure, primary angle closure glaucoma, and acute primary angle closure. Accumulating evidence suggests that the pathogenesis of PACD is complex, with multiple contributory factors including variations in the anatomic or biometric characteristics of the angle segment structures. Advances in anterior segment optical coherence tomography technology have further enhanced our understanding of the risk factors ...
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    11. Recent advances in anterior chamber angle imaging

      Recent advances in anterior chamber angle imaging
      Differentiating the two main forms of primary glaucoma (open-angle and closed-angle glaucoma) depends on the correct assessment of the anterior chamber angle (ACA). This assessment will determine the management plan and prognosis for the disease. The standard method of examining the angle has been, for many years, slit-lamp gonioscopy. This method, although clinically still useful, is less robust for patient follow up and clinical research, given its low reproducibility. Several ...
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    12. DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images

      DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images
      Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: 2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were used to train a generative adversarial network (GAN) using a custom loss function.Image quality was assessed qualitatively (for artifacts) and quantitatively using the intralayer contrast € a measure of shadow ...
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    13. A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head

      A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head
      Optical coherence tomography (OCT) has become an established clinical routine for the in vivo imaging of the optic nerve head (ONH) tissues, that is crucial in the diagnosis and management of various ocular and neuro-ocular pathologies. However, the presence of speckle noise affects the quality of OCT images and its interpretation. Although recent frame-averaging techniques have shown to enhance OCT image quality, they require longer scanning durations, resulting in patient ...
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    14. Upside-down position leads to choroidal expansion and anterior chamber shallowing: OCT study

      Upside-down position leads to choroidal expansion and anterior chamber shallowing: OCT study
      Background To determine whether dynamic changes in choroidal thickness (CT) cause shallowing of the anterior chamber. Methods 34 healthy volunteers were enrolled. The participants in our study adopted the upside-down position for 1.5min, which was the model we used to study the dynamic changes in CT. Intraocular pressure (IOP) elevation, optical coherence tomography images of the choroid and anterior chamber were obtained at baseline, after being in an upside-down ...
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    15. Understanding diagnostic disagreement in angle closure assessment between anterior segment optical coherence tomography and gonioscopy

      Understanding diagnostic disagreement in angle closure assessment between anterior segment optical coherence tomography and gonioscopy
      Background/aims Although being a more objective tool for assessment and follow-up of angle closure, reliability studies have reported a moderate diagnostic performance for anterior segment optical coherence tomography (OCT) technologies when comparing with gonioscopy as the reference standard. We aim to determine factors associated with diagnostic disagreement in angle closure when assessed by anterior segment swept source OCT (SS-OCT, CASIA SS-1000; Tomey, Nagoya, Japan) and gonioscopy. Methods Cross-sectional study ...
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    16. Anterior Segment Optical Coherence Tomography Is there a Clinical Role in Management of Primary Angle Closure Disease?

      Anterior Segment Optical Coherence Tomography Is there a Clinical Role in Management of Primary Angle Closure Disease?
      Primary angle-closure disease (PACD) covers a spectrum that includes primary angle-closure suspect (PACS), primary angle-closure (PAC), primary angle-closure glaucoma (PACG), as well as acute primary angle closure (APAC). Accumulating evidence suggests that the pathogenesis of PACD is complex, with multiple contributory factors including variations in the anatomical or biometric characteristics of the angle segment structures. Advances in anterior segment optical coherence tomography (ASOCT) technology have further enhanced our understanding of ...
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    17. 1-15 of 95 1 2 3 4 5 6 7 »
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  2. About Tin Aung

    Tin Aung

    Aung Tin is an Associate Professor of Ophthalmology with the Singapore Eye Research Institute and Singapore National Eye Centre and with the Department of Ophthalmology at the Yong Loo Lin School of Medicine, National University of Singapore.

  3. Quotes

    1. We hope that this new lab between SNEC-SERI and NTU will be the start of an important programme to utilise engineering solutions to help and improve care of our patients with eye problems.
      In NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies