1. Tin Aung

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    1. Mentioned In 91 Articles

    2. Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study

      Explore LWW Online Ophthalmology
      Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study
      Precis: Angle closure worsens with pharmacological dilatation in about 50.0% of the subjects diagnosed as primary angle closure suspects. Purpose: To evaluate the changes in angle configuration with swept source anterior segment optical coherence tomography before and after pharmacological pupil dilatation in untreated primary angle closure suspects. Patients Methods: 106 subjects over the age of 50 years and diagnosed as primary angle closure suspects were included in this cross-sectional ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Tomey Corporation

    3. Evaluation of meridional scans for angle closure assessment with anterior segment swept-source optical coherence tomography

      Explore BJO Online Ophthalmology
      Evaluation of meridional scans for angle closure assessment with anterior segment swept-source optical coherence tomography
      Background/aims As swept-source optical coherence tomography (SS-OCT) simultaneously obtains 128 meridional scans, it is important to identify which scans are playing the main role in classifying gonioscopic angle closure to simplify the analysis. We aimed to evaluate the diagnostic performance of every meridional scan in its ability to detect gonioscopic angle closure. Methods Observational study with 2027 phakic subjects consecutively recruited from a community polyclinic. Gonioscopy and SS-OCT were ...
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      Mentions: Singapore Eye Research Institute Harvard University National University of Singapore

    4. Towards Label-Free 3D Segmentation of Optical Coherence Tomography Images of the Optic Nerve Head Using Deep Learning

      Explore arxiv.org Ophthalmology
      Towards Label-Free 3D Segmentation of Optical Coherence Tomography Images of the Optic Nerve Head Using Deep Learning
      Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep learning (DL) techniques have been recently proposed for the automated extraction (segmentation) and quantification of these morphological changes, the device-specific nature and the difficulty in preparing manual segmentations (training data) limit their clinical ...
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      Mentions: Duke University Medical University of Vienna Singapore Eye Research Institute

    5. NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies

      Explore Optical Coherence Tomography News Ophthalmology , Partnership
      NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies
      ...ecord in translational research excellence, which supports Singapore's vibrant research ecosystem.” Professor Aung Tin, Executive Director, Singapore Eye Research Institute, said, “We hope that this new lab between SNEC-...
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      Mentions: Imperial College London Singapore Eye Research Institute Nanyang Technological University

    6. Anterior Segment Optical Coherence Tomography: Is There a Clinical Role in the Management of Primary Angle Closure Disease?

      Explore LWW Online Ophthalmology
      Anterior Segment Optical Coherence Tomography: Is There a Clinical Role in the Management of Primary Angle Closure Disease?
      Primary angle closure disease (PACD) covers a spectrum that includes primary angle closure suspect, primary angle closure, primary angle closure glaucoma, and acute primary angle closure. Accumulating evidence suggests that the pathogenesis of PACD is complex, with multiple contributory factors including variations in the anatomic or biometric characteristics of the angle segment structures. Advances in anterior segment optical coherence tomography technology have further enhanced our understanding of the risk factors ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Tin Aung

    7. Recent advances in anterior chamber angle imaging

      Explore Nature Publishing Group Ophthalmology
      Recent advances in anterior chamber angle imaging
      Differentiating the two main forms of primary glaucoma (open-angle and closed-angle glaucoma) depends on the correct assessment of the anterior chamber angle (ACA). This assessment will determine the management plan and prognosis for the disease. The standard method of examining the angle has been, for many years, slit-lamp gonioscopy. This method, although clinically still useful, is less robust for patient follow up and clinical research, given its low reproducibility. Several ...
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      Mentions: Singapore Eye Research Institute Tomey Corporation Mani Baskaran

    8. DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images

      Explore arxiv.org Ophthalmology
      DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images
      Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: 2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were used to train a generative adversarial network (GAN) using a custom loss function.Image quality was assessed qualitatively (for artifacts) and quantitatively using the intralayer contrast € a measure of shadow ...
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      Mentions: Cardiff University Nanyang Technological University National University of Singapore

    9. A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head

      Explore Nature Publishing Group Ophthalmology
      A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head
      Optical coherence tomography (OCT) has become an established clinical routine for the in vivo imaging of the optic nerve head (ONH) tissues, that is crucial in the diagnosis and management of various ocular and neuro-ocular pathologies. However, the presence of speckle noise affects the quality of OCT images and its interpretation. Although recent frame-averaging techniques have shown to enhance OCT image quality, they require longer scanning durations, resulting in patient ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Nanyang Technological University

    10. Upside-down position leads to choroidal expansion and anterior chamber shallowing: OCT study

      Explore BJO Online Ophthalmology
      Upside-down position leads to choroidal expansion and anterior chamber shallowing: OCT study
      Background To determine whether dynamic changes in choroidal thickness (CT) cause shallowing of the anterior chamber. Methods 34 healthy volunteers were enrolled. The participants in our study adopted the upside-down position for 1.5min, which was the model we used to study the dynamic changes in CT. Intraocular pressure (IOP) elevation, optical coherence tomography images of the choroid and anterior chamber were obtained at baseline, after being in an upside-down ...
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      Mentions: Sun Yat-Sen University Chinese Academy of Sciences Tin Aung

    11. Understanding diagnostic disagreement in angle closure assessment between anterior segment optical coherence tomography and gonioscopy

      Explore BJO Online Ophthalmology
      Understanding diagnostic disagreement in angle closure assessment between anterior segment optical coherence tomography and gonioscopy
      Background/aims Although being a more objective tool for assessment and follow-up of angle closure, reliability studies have reported a moderate diagnostic performance for anterior segment optical coherence tomography (OCT) technologies when comparing with gonioscopy as the reference standard. We aim to determine factors associated with diagnostic disagreement in angle closure when assessed by anterior segment swept source OCT (SS-OCT, CASIA SS-1000; Tomey, Nagoya, Japan) and gonioscopy. Methods Cross-sectional study ...
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      Mentions: Singapore Eye Research Institute David S. Friedman Massachusetts Eye and Ear Infirmary

    12. Anterior Segment Optical Coherence Tomography Is there a Clinical Role in Management of Primary Angle Closure Disease?

      Explore LWW Online Ophthalmology
      Anterior Segment Optical Coherence Tomography Is there a Clinical Role in Management of Primary Angle Closure Disease?
      Primary angle-closure disease (PACD) covers a spectrum that includes primary angle-closure suspect (PACS), primary angle-closure (PAC), primary angle-closure glaucoma (PACG), as well as acute primary angle closure (APAC). Accumulating evidence suggests that the pathogenesis of PACD is complex, with multiple contributory factors including variations in the anatomical or biometric characteristics of the angle segment structures. Advances in anterior segment optical coherence tomography (ASOCT) technology have further enhanced our understanding of ...
      Read Full Article
      Mentions: Singapore Eye Research Institute National University of Singapore Tin Aung

    13. Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders

      Explore BJO Online Ophthalmology
      Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders
      Background/Aims To compensate the retinal nerve fibre layer (RNFL) thickness assessed by spectral-domain optical coherence tomography (SD-OCT) for anatomical confounders. Methods The Singapore Epidemiology of Eye Diseases is a population-based study, where 2698 eyes (1076 Chinese, 704 Malays and 918 Indians) with high-quality SD-OCT images from individuals without eye diseases were identified. Optic disc and macular cube scans were registered to determine the distance between fovea and optic disc ...
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      Mentions: Singapore Eye Research Institute The Chinese University of Hong Kong Tin Aung

    14. A Deep Learning System for Automated Angle-Closure Detection in Anterior Segment Optical Coherence Tomography Images

      Explore American Journal of Ophthalmology Ophthalmology
      A Deep Learning System for Automated Angle-Closure Detection in Anterior Segment Optical Coherence Tomography Images
      Purpose Anterior segment optical coherence tomography (AS-OCT) provides an objective imaging modality for visually identifying anterior segment structures. An automated detection system could assist ophthalmologists in interpreting AS-OCT images for presence of angle closure. Design Development of an artificial intelligence automated detection system for the presence of angle closure. Methods A deep learning system for automated angle-closure detection in AS-OCT images was developed, and this was compared with another automated ...
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      Mentions: Singapore Eye Research Institute Mani Baskaran Tin Aung

    15. Assessment of Circumferential Angle Closure with Swept-Source Optical Coherence Tomography: a community based study

      Explore American Journal of Ophthalmology Ophthalmology
      Assessment of Circumferential Angle Closure with Swept-Source Optical Coherence Tomography: a community based study
      Purpose To evaluate the diagnostic performance of swept-source optical coherence tomography (SS-OCT, CASIA SS-1000, Tomey Corporation, Nagoya, Japan) for angle closure detection, in comparison with gonioscopy in a community setting. Design Reliability analysis. Methods A total of 2027 phakic subjects aged 50 years, with no previous history of glaucoma, laser (including peripheral iridotomy), intraocular surgery or ocular trauma, were consecutively recruited from a community polyclinic in Singapore. Gonioscopy was performed ...
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      Mentions: Johns Hopkins University Singapore Eye Research Institute David S. Friedman

    16. DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images

      Explore OSA | OSA Publishing Ophthalmology
      DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images
      Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology. A deep learning algorithm (custom U-NET) was designed and trained to segment 6 ONH tissue layers by capturing both the local (tissue texture ...
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      Mentions: University College London Singapore Eye Research Institute National University of Singapore
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  4. About Tin Aung

    Tin Aung

    Aung Tin is an Associate Professor of Ophthalmology with the Singapore Eye Research Institute and Singapore National Eye Centre and with the Department of Ophthalmology at the Yong Loo Lin School of Medicine, National University of Singapore.

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  6. Quotes

    1. We hope that this new lab between SNEC-SERI and NTU will be the start of an important programme to utilise engineering solutions to help and improve care of our patients with eye problems.
      In NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies