Articles that mention Tien Yin Wong -Optical Coherence Tomography News

Tien Yin Wong

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1. Mentioned In 41 Articles
2. Impact of systemic vascular risk factors on the choriocapillaris using optical coherence tomography angiography in patients with systemic hypertension
  
  Explore Nature Publishing Group Apr 12 2019 Ophthalmology
  
  We investigated the characteristics of the choriocapillaris flow voids using optical coherence tomography angiography (OCTA) in 85 patients (164 eyes) with hypertension (meanSD age, 5611 years; 45% women; 20% poorly controlled BP; 16% diabetes) who are without ocular diseases and determined possible correlations with systemic vascular risk factors. Data on 24-hour ambulatory blood pressure (BP), serum creatinine, and urine microalbumin/creatinine ratio (MCR) were collected. Estimated glomerular filtration rate (eGFR ...
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  Mentions: Medical University of Vienna Singapore Eye Research Institute Tien Yin Wong
3. Artificial intelligence and deep learning in ophthalmology
  
  Explore BJO Online Oct 25 2018 Ophthalmology
  
  Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc ...
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  Mentions: University College London Medical University of Vienna Oregon Health & Science University
4. Correlation of Color Fundus Photograph Grading with Risks of Early Age-related Macular Degeneration by using Automated OCT-derived Drusen Measurements
  
  Explore Nature Publishing Group Sep 1 2018 Ophthalmology
  
  We evaluated automated OCT-derived drusen volume measures in a population-based study (n=4,512) aged 40 years, and its correlation with conventional color fundus photographs (CFP)-derived early AMD features. Participants had protocol-based assessment to capture medical and ocular history, genotyping for SNPs in CFH , ARMS2 , and CETP , CFP-based AMD grading and automated drusen volume based on SD-OCT using built-in software (Cirrus OCT advanced RPE analysis software). Significantly fewer eyes ...
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  Mentions: Singapore Eye Research Institute Paul Mitchell Tien Yin Wong
5. Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy
  
  Explore LWW Online Aug 22 2018 Ophthalmology
  
  Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with antivascular endothelial growth factor monotherapy or combined with photodynamic therapy . Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer ...
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  Mentions: Singapore Eye Research Institute National University of Singapore Tien Yin Wong
6. Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis
  
  Explore ScienceDirect Aug 16 2018 Neurology , Ophthalmology
  
  Topic Optical coherence tomography (OCT) is a non-invasive tool to measure specific retinal layers in the eye. The relationship of retinal spectral domain-OCT (SD-OCT) measurements with Alzheimers Disease (AD) and mild cognitive impairment (MCI) remains unclear. Hence, we conducted a systematic review and meta-analysis to examine the SD-OCT measurements in AD and MCI. Clinical Relevance Current methods of diagnosing early AD are expensive and invasive. Retinal measurements of SD-OCT, which ...
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  Mentions: Singapore Eye Research Institute National University of Singapore The Chinese University of Hong Kong
7. IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
  
  Explore LWW Online Jun 26 2018 Ophthalmology
  
  Purpose: To assess the ability of optical coherence tomography (OCT) alone and in combination with OCT angiography (OCTA) to differentiate polypoidal choroidal vasculopathy (PCV) from neovascular age-related macular degeneration , as compared to fluorescein angiography and indocyanine green angiography. Methods: This is a cross-sectional study. All participants had a standardized history, clinical examination including measurement of best-corrected visual acuity, slit-lamp biomicroscopy, and indirect fundus examination, and underwent standardized imaging (color photography ...
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  Mentions: Singapore Eye Research Institute Masahiro Akiba Tien Yin Wong
8. Clinical Use of Optical Coherence Tomography Angiography in Diabetic Retinopathy Treatment Ready for Showtime?
  
  Explore The JAMA Network May 29 2018 Ophthalmology
  
  Diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) are the 2 advanced stages of diabetic retinopathy (DR) that are the main causes for visual loss in patients with diabetes. Both DME and PDR can be readily diagnosed with clinical examination and, increasingly, by the noninvasive use of optical coherence tomography. However, another, less commonly recognized cause of visual loss in patients with diabetes is diabetic macular ischemia (DMI) in ...
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  Mentions: Duke University Singapore Eye Research Institute National University of Singapore
9. AI for medical imaging goes deep
  
  Explore Nature Publishing Group May 7 2018 Ophthalmology
  
  An artificial intelligence (AI) using a deep-learning approach can classify retinal images from optical coherence tomography for early diagnosis of retinal diseases and has the potential to be used in other image-based medical diagnoses.
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  Mentions: Tien Yin Wong
10. Identification of imaging features that determine quality and repeatability of retinal capillary plexus density measurements in OCT angiography
  
  Explore BJO Online Sep 2 2017 Ophthalmology
  
  Purpose Optical coherence tomography angiography (OCT-A) potentially allows for rapid and non-invasive quantification of retinal capillary plexus density in various disease states. This study aims to identify the key features that influenced the repeatability of OCT-A measurements. Methods We obtained OCT-A images on two separate visits in 44 healthy eyes from 44 subjects, each imaged with using the Topcon DRI OCT Triton imaging system. The parafoveal vessel density within a ...
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  Mentions: Topcon Medical Systems Singapore Eye Research Institute National University of Singapore
11. Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-domain Optical Coherence Tomography in Patients with Cognitive Impairment
  
  Explore journal.frontiersin.org Aug 7 2017 Neurology , Ophthalmology
  
  Background: With increasing interest in determining if measurement of retinal neuronal structure with spectral-domain optical coherence tomography (SD-OCT) is useful in accessing neurodegenerative process in cognitive decline and development of dementia, it is important to evaluate whether the SD-OCT measurements are repeatable and reproducible in patients with Alzheimers disease (AD) or mild cognitive impairment (MCI). Methods: This is a retrospective cohort study. Patients with AD or MCI with no change ...
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  Mentions: Singapore Eye Research Institute Carl Zeiss Meditec University of Melbourne
12. COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY
  
  Explore LWW Online Aug 5 2017 Ophthalmology
  
  Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with anti-vascular endothelial growth factor monotherapy or combined with photodynamic therapy. Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer ...
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  Mentions: Singapore Eye Research Institute Tien Yin Wong
13. Determinants of Quantitative Optical Coherence Tomography Angiography Metrics in Patients with Diabetes
  
  Explore Nature Publishing Group Jun 6 2017 Ophthalmology
  
  Early microvascular damage in diabetes (e.g. capillary nonperfusion and ischemia) can now be assessed and quantified with optical coherence tomography-angiography (OCT-A). The morphology of vascular tissue is indeed affected by different factors; however, there is a paucity of data examining whether OCT-A metrics are influenced by ocular, systemic and demographic variables in subjects with diabetes. We conducted an observational cross-sectional study and included 434 eyes from 286 patients with ...
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  Mentions: Singapore Eye Research Institute The Chinese University of Hong Kong Tien Yin Wong
14. Factors affecting signal strength in spectral-domain optical coherence tomography
  
  Explore Wiley Online Library Apr 9 2017 Ophthalmology
  
  Purpose To identify ocular factors that affect signal strength in spectral-domain optical coherence tomography (SD-OCT). Methods Data from 1312 participants of the population-based Singapore Malay Eye Study-2 (SiMES-2) were included in the analysis. All participants underwent standardized ophthalmic examination, including measurements of best-corrected visual acuity (BCVA), refractive error, axial length, corneal curvature and presence of cataracts. Optic disc and macular cube scans were acquired using the Cirrus HD-OCT (software version ...
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  Mentions: Carl Zeiss Meditec Tien Yin Wong
15. Detailed Phenotyping and Characterization of Choroidal Morphological and Vascular Features in Young Men with High Myopia Using Spectral-Domain Optical Coherence Tomography
  
  Explore Elsevier Health Feb 13 2017 Ophthalmology
  
  Purpose To describe detailed morphological and vascular features of the choroid in eyes with high myopia. Design Cross-sectional study. Methods 515 eyes of young men (mean age 21.591.15) years) with high myopia (defined as -6.0 D or worse, mean spherical equivalent -8.662.00 D) and 88 controls with emmetropia in both eyes underwent choroidal imaging using spectral domain optical coherence tomography with enhanced depth imaging (EDI-OCT ...
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  Mentions: Singapore Eye Research Institute Tien Yin Wong
16. Artificial Intelligence With Deep Learning Technology Looks Into Diabetic Retinopathy Screening
  
  Explore The JAMA Network Nov 29 2016 Ophthalmology
  
  D iabetic retinopathy is a leading cause of vision loss in the United States and globally, particularly among working-aged individuals. Diabetic retinopathy meets all the criteria for screening: first, the condition (diabetic retinopathy) is an important public health care problem; second, the epidemiology and natural history of the condition, including development from asymptomatic latent to severe disease, are adequately understood; third, the screening test (retinal photography) is simple, safe, validated ...
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  Mentions: Johns Hopkins University Singapore Eye Research Institute National University of Singapore
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