1. Tianjin University

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    1. Mentioned In 58 Articles

    2. Insights into the developing fovea revealed by imaging

      Insights into the developing fovea revealed by imaging
      Early development of the fovea has been documented by histological studies over the past few decades. However, structural distortion due to sample processing and the paucity of high-quality post-mortem tissue has limited the effectiveness of this approach. With the continuous progress in high-resolution non-invasive imaging technology, most notably optical coherence tomography (OCT) and OCT angiography (OCT-A), in vivo visualization of the developing retina has become possible. Combining the information from ...
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    3. A pilot and ex-vivo study of examination of endometrium tissue by catheter based optical coherence tomography

      A pilot and ex-vivo study of examination of endometrium tissue by catheter based optical coherence tomography
      Objective This study aimed to distinguish ex-vivo normal and abnormal endometrium tissue samples histologically by catheter based optical coherence tomography (OCT). Methods A total of 72 ex-vivo endometrium specimens were obtained from June 2018 to March 2021 and were imaged fresh after hysterectomy. The scanned region of endometrium was excised for histological examination and endometrium OCT images were precisely compared to corresponding histological images. Meanwhile endometrium OCT images were analyzed ...
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    4. Advanced ultrawide-field optical coherence tomography angiography identifies previously undetectable changes in biomechanics-related parameters in nonpathological myopic fundus

      Advanced ultrawide-field optical coherence tomography angiography identifies previously undetectable changes in biomechanics-related parameters in nonpathological myopic fundus
      Purpose: To detect previously undetectable changes in vessel density and structural thickness, the two biomechanics-related parameters reflecting hemodynamics and tensile strength, respectively, in the peripheral and central fundi of nonpathological myopic eyes with an advanced ultrawide-field optical coherence tomography angiography (OCTA) system. Methods: A cross-sectional observational clinical study was carried out by recruiting 155 eyes from 79 college students aged 18-28 years. The eyes were stratified into normal, low-myopia, medium-myopia ...
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    5. Assessment of macular structures and vascular characteristics in highly myopic anisometropia using swept-source optical coherence tomography angiography

      Assessment of macular structures and vascular characteristics in highly myopic anisometropia using swept-source optical coherence tomography angiography
      Purpose: This study aimed to explore the macular structures and vascular characteristics of more myopic (MM) and contralateral eyes with highly myopic anisometropia. Methods: Comprehensive ophthalmic examinations were performed for 33 patients with highly myopic anisometropia. Macular structures (total retinal layer [TRL], ganglion cell and inner plexiform layer [GCIPL], inner nuclear layer [INL], outer retinal layer [ORL], nerve fiber layer [NFL], choroidal layer [CHL]) and vascular characteristics (superficial vascular complex ...
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    6. Automatic bifurcation detection utilizing pullback characteristics of bifurcation in intravascular optical coherence tomography

      Automatic bifurcation detection utilizing pullback characteristics of bifurcation in intravascular optical coherence tomography
      Bifurcation detection in coronary arteries is significant since it influences the treatment strategy selection and optimization. Bifurcations are also reliable landmarks for image registration. Intravascular optical coherence tomography (IVOCT) is a high-resolution imaging modality that is very useful in percutaneous coronary intervention stenting optimization. We present a bifurcation identification method utilizing pullback characteristics for IVOCT, which can effectively identify the bifurcations with a small size. The longitudinal view of the ...
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    7. Image enhancement of wide-field retinal optical coherence tomography angiography by super-resolution angiogram reconstruction generative adversarial network

      Image enhancement of wide-field retinal optical coherence tomography angiography by super-resolution angiogram reconstruction generative adversarial network
      Wide-field retinal optical coherence tomography angiography (OCTA) usually suffers from low image resolution in clinical practice because of insufficient lateral sampling. In this study, we develop a deep-learning-based method named super-resolution angiogram reconstruction generative adversarial network (SAR-GAN) to enhance the en face OCTA image quality. A sophisticated home-made spectral-domain OCTA system is employed to capture the data of retinal angiograms with different scanning protocols. High-resolution 3 3 mm 2 OCTA ...
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    8. Evaluation of the repeatability of optical coherence tomography in patients with age-related cataract associated with dry eye

      Evaluation of the repeatability of optical coherence tomography in patients with age-related cataract associated with dry eye
      Aim To assess the repeatability of a new optical biometer (OA-2000, Tomey, Japan) based on swept-source optical coherence tomography (SS-OCT) and Placido-disk topography in dry eyes with cataracts. Method A cross-sectional study was performed. Two hundred sixteen eyes of 216 cataract patients were enrolled in our hospital from March 2020 to December 2020. According to the subjective symptoms and objective examination of dry eye, the patients were assigned to dry ...
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    9. Changes in the peripapillary vasculature and macular thickness after cataract surgery using two phacoemulsification systems with optical coherence tomography angiography

      Changes in the peripapillary vasculature and macular thickness after cataract surgery using two phacoemulsification systems with optical coherence tomography angiography
      Aim: To assess the changes in the peripapillary vasculature and macular thickness after cataract surgery using two phacoemulsification systems with optical coherence tomography angiography (OCTA). Methods: Fifty-two eyes of 52 patients with age-related cataract were randomized into two groups for phacoemulsification: Infiniti group (26 patients) using the Infiniti phacoemulsification system with gravity-fluidics and Centurion group (26 patients) using the Centurion phacoemulsification system with active-fluidics. The peripapillary vessel density (PVD) and ...
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    10. Diagnostic Value of Spectral-Domain Optical Coherence Tomography for Polypoidal Choroidal Vasculopathy: A Systematic Review and Meta-Analysis

      Diagnostic Value of Spectral-Domain Optical Coherence Tomography for Polypoidal Choroidal Vasculopathy: A Systematic Review and Meta-Analysis
      Purpose: To evaluate the diagnostic value of spectral-domain optical coherence tomography (SD-OCT) for polypoidal choroidal vasculopathy (PCV). Methods: A search of electronic databases was conducted from 2010 to 2021 to review the relevant literature on SD-OCT to identify PCV and other lesions causing serious or serosanguinous retinal pigment epithelial detachment (PED), specifically neovascular age-related macular degeneration (nvAMD). The QUADAS-2 scale was used to evaluate the quality of the literature. We ...
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    11. Measurement of Layer-Specific Mechanical Properties of Intact Blood Vessels Based on Intravascular Optical Coherence Tomography

      Measurement of Layer-Specific Mechanical Properties of Intact Blood Vessels Based on Intravascular Optical Coherence Tomography
      Purpose: The biomechanical analysis of stress and strain state of multilayered blood vessels has shown great importance in vascular pathology and physiology. However, there is a lack of method in measuring the mechanical property of each layer of a vascular sample without splitting up the wall. Methods: Here we develop a vascular inflation test method based on intravascular optical coherence tomography (IVOCT) imaging and inverse parametric estimation. We propose a ...
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    12. Measuring Human Corneal Stromal Biomechanical Properties Using Tensile Testing Combined With Optical Coherence Tomography

      Measuring Human Corneal Stromal Biomechanical Properties Using Tensile Testing Combined With Optical Coherence Tomography
      Purpose: To investigate the ex vivo elastic modulus of human corneal stroma using tensile testing with optical coherence tomography (OCT) imaging and its correlation with in vivo measurements using corneal visualization Scheimpflug technology. Methods: Twenty-four corneal specimens extracted from stromal lenticules through small incision lenticule extraction were cut into strips for uniaxial tensile tests. In vivo corneal biomechanical responses were evaluated preoperatively using the corneal visualization Scheimpflug technology (CorVis ST ...
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    13. Analysis and reduction of noise-induced depolarization in catheter based polarization sensitive optical coherence tomography

      Analysis and reduction of noise-induced depolarization in catheter based polarization sensitive optical coherence tomography
      In catheter based polarization sensitive optical coherence tomography (PS-OCT), a optical fiber with a rapid rotation in the catheter can cause low signal-to-noise ratio (SNR), polarization state instability, phase change of PS-OCT signals and then heavy noise-induced depolarization, which has a strong impact on the phase retardation measurement of the sample. In this paper, we analyze the noise-induced depolarization and find that the effect of depolarization can be reduced by ...
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    14. In Vivo Intravascular Optical Coherence Tomography (IVOCT) Structural and Blood Flow Imaging Based Mechanical Simulation Analysis of a Blood Vessel

      In Vivo Intravascular Optical Coherence Tomography (IVOCT) Structural and Blood Flow Imaging Based Mechanical Simulation Analysis of a Blood Vessel
      Introduction: Computer modelling of blood vessels based on biomedical imaging provides important hemodynamic and biomechanical information for vascular disease studies and diagnosis. However due to lacking well-defined physiological blood flow profiles, the accuracy of the simulation results is often not guaranteed. Flow velocity profiles of a specific cross section of a blood vessel were obtained by in vivo Doppler intravascular optical coherence tomography (IVOCT) lately. However due to the influence ...
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    15. Biometric Indicators of Anterior Segment Parameters Before and After Laser Peripheral Iridotomy by Swept-Source Optical Coherent Tomography

      Biometric Indicators of Anterior Segment Parameters Before and After Laser Peripheral Iridotomy by Swept-Source Optical Coherent Tomography
      Background Primary angle closure glaucoma (PACG) is the most common type of glaucoma in China. Laser peripheral iridotomy (LPI) is the primary choice to treat PAC. We aim to evaluate the changes and to find the biometric indicators of anterior segment parameters before and after laser peripheral iridotomy (LPI) in primary angle closure (PAC) eyes using swept-source optical coherent tomography (OCT). Methods LPI was performed in 52 PAC eyes of ...
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    16. Comparison of similar Mueller and Jones matrix method in catheter based polarization sensitive optical coherence tomography

      Comparison of similar Mueller and Jones matrix method in catheter based polarization sensitive optical coherence tomography
      Catheter based polarization sensitive optical coherence tomography (PS-OCT) can provide composition information of coronary atherosclerotic plaque beyond the intensity based OCT, but it encounters a notable challenge that is how to reduce polarization properties variations owing to a rapidly rotating optical fiber in the catheter. Similar Jones matrix (SJM) and similar Mueller matrix (SMM) based polarization determination methods can provide a stable phase retardation imaging in a catheter based PS-OCT ...
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  2. About Tianjin University

    Tianjin University

    Tianjin University  is a national university under the direct administration of the Ministry of Education of China. It is the first university in modern Chinese education history.