1. Thomas M. Jørgensen

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    1. Mentioned In 20 Articles

    2. Quantitatively Measured Anatomic Location and Volume of Optic Disc Drusen: An Enhanced Depth Imaging Optical Coherence Tomography Study

      Quantitatively Measured Anatomic Location and Volume of Optic Disc Drusen: An Enhanced Depth Imaging Optical Coherence Tomography Study
      Purpose : Optic disc drusen (ODD) are found in up to 2.4% of the population and are known to cause visual field defects. The purpose of the current study was to investigate how quantitatively estimated volume and anatomic location of ODD influence optic nerve function. Methods : Anatomic location, volume of ODD, and peripapillary retinal nerve fiber layer and macular ganglion cell layer thickness were assessed in 37 ODD patients using ...
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    3. Optical tissue clearing improves usability of optical coherence tomography (OCT) for high-throughput analysis of the internal structure and 3D morphology of small biological objects such as vertebrate embryos

      Optical tissue clearing improves usability of optical coherence tomography (OCT) for high-throughput analysis of the internal structure and 3D morphology of small biological objects such as vertebrate embryos
      ...he internal structure and 3D morphology of small biological objects such as vertebrate embryos Lars Thrane ; Thomas M. Jørgensen ; Jörg Männer; Optical tissue clearing improves usability of optical coherence tomography ...
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    4. An elegant technique for ex vivo imaging in experimental research - optical coherence tomography (OCT)

      An elegant technique for ex vivo imaging in experimental research - optical coherence tomography (OCT)
      Optical coherence tomography (OCT) is an elegant technology for imaging of tissues and organs and has been established for clinical use for around a decade. Thus, it is used in vivo but can also serve as a valuable ex vivo imaging tool in experimental research. Here, a brief overview is given with a focus on an ex vivo application of OCT. Image and video examples of freshly obtained murine lungs ...
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    5. Feature Of The Week 12/4/11: Technical University of Denmark Demonstrates First OCT Imaging of Polymer Solar Cell Modules

      Feature Of The Week 12/4/11: Technical University of Denmark Demonstrates First OCT Imaging of Polymer Solar Cell Modules
      The Technical University of Denmark (DTU) has demonstrated the first application of optical coherence tomography (OCT) as a 3-dimensional (3D) imaging technique to visualize the internal structure of complete multilayered polymer solar cell modules. The work has been carried out in a cross-disciplinary collaboration between DTU Fotonik/Department of Photonics Engineering and Risø National Laboratory for Sustainable Energy, both part of DTU.The 3D imaging of complete polymer solar cells ...
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    6. Application of optical coherence tomography (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells

      Application of optical coherence tomography (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells
      ...graphy (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells Lars Thrane^a, Thomas M. Jørgensen^a, Mikkel Jørgensen^b, Frederik C. Krebs^b^, Corresponding Author Contact Information ^, ...
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    7. How histological features of basal cell carcinomas influence image quality in optical coherence tomography

      How histological features of basal cell carcinomas influence image quality in optical coherence tomography
      Optical coherence tomography (OCT) has the potential to diagnose and measure the depth of nonmelanoma skin cancer (NMSC) in skin, but some lesions appear blurred in OCT images. The aim of this study is to identify histological characteristics of basal cell carcinomas (BCC) that correlate with good quality OCT images of the same lesions. A total of 34 patients with BCC were OCT scanned. The influence of histology parameters (e ...
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    8. Open Post Doc/Research Assistant position: Swept-source optical coherence tomography system for ophthalmic use at Technical University of Denmark

      Open Post Doc/Research Assistant position: Swept-source optical coherence tomography system for ophthalmic use at Technical University of Denmark
      Optical coherence tomography (OCT) is an emerging imaging technology that enables high-resolution, cross-sectional imaging in biological tissues. OCT has been especially powerful for ophthalmic imaging, where it can provide images of retinal pathology with unprecedented resolutions. We seek a Post Doc/Research Assistant to finalize a project on the development of a 1050nm swept-source OCT system for ophthalmic use. The project is part of an existing collaboration with the major ...
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    9. Optical Coherence Tomography for Imaging of Skin and Skin Diseases

      Optical coherence tomography (OCT) is an emerging imaging technology based on light reflection. It provides real-time images with up to 2-mm penetration into the skin and a resolution of approximately 10 μm. It is routinely used in ophthalmology. The normal skin and its appendages have been studied, as have many diseases. The method can provide accurate measures of epidermal and nail changes in normal tissue. Skin cancer and other tumors ...
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    10. Macular morphology and visual acuity after macular hole surgery with or without internal limiting membrane peeling

      Aim: To examine postoperative macular morphology and visual outcome after 12 months in relation to internal limiting membrane (ILM) peeling versus no peeling, indocyanine green (ICG)-staining, and reoperation in eyes that achieved macular hole closure after surgery. Methods: Seventy-four eyes with closed stage 2 or 3 macular holes were recruited from a randomized clinical trial comparing (1) vitrectomy without ILM peeling, (2) vitrectomy with 0.05 % isotonic ICG-assisted ILM ...
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    11. Which histological characteristics of basal cell carcinomas influence the quality of optical coherence tomography imaging?

      ...ce Chairs: Peter E. Andersen, Brett E. Bouma ABSTRACT M. Mogensen Univ. of Copenhagen (Denmark) L. Thrane and T. M. Joergensen Technical Univ. of Denmark (Denmark) B. M. Nürnberg and G. B. E. Jemec Univ. of Copenhagen (D...
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    12. OCT imaging of skin cancer and other dermatological diseases

      Optical coherence tomography (OCT) provides clinicians and researchers with micrometer-resolution, in vivo, cross-sectional images of human skin up to several millimeter depth. This review of OCT imaging applied within dermatology covers the application of OCT to normal skin, and reports on a large number of applications in the fields of non-melanoma skin cancer, malignant melanomas, psoriasis and dermatitis, infestations, bullous skin diseases, tattoos, nails, haemangiomas, and other skin diseases
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    13. Assessment of Optical Coherence Tomography Imaging in the Diagnosis of Non-Melanoma Skin Cancer and Benign Lesions Versus Normal Skin: Observer-Blinded Evaluation by Dermatologists and Pathologists

      BACKGROUND Optical coherence tomography (OCT) is an optical imaging technique that may be useful in diagnosis of non-melanoma skin cancer (NMSC). OBJECTIVES To describe OCT features in NMSC such as actinic keratosis (AK) and basal cell carcinoma (BCC) and in benign lesions and to assess the diagnostic accuracy of OCT in differentiating NMSC from benign lesions and normal skin. METHODS AND MATERIALS OCT and polarization-sensitive (PS) OCT from 104 patients ...
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    14. Axonal loss occurs early in dominant optic atrophy

      Purpose: This study set out to investigate retinal nerve fibre layer (RNFL) thickness and best corrected visual acuity (BCVA) in relation to age in healthy subjects and patients with OPA1 autosomal dominant optic atrophy (DOA).Methods: We carried out a cross-sectional investigation of RNFL thickness and ganglion cell layer density in 30 healthy subjects and 10 patients with OPA1 DOA using optical coherence tomography (OCT). We then performed a regression ...
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    15. Optical Coherence Tomography: Technique and Applications (Book Chapter)

      Optical Coherence Tomography: Technique and Applications (Book Chapter)
      Optical coherence tomography (OCT) is a noninvasive optical imaging modality providing real-time video rate images in two and three dimensions of biological tissues with micrometer resolution. OCT fills the gap between ultrasound and confocal microscopy, since it has a higher resolution than ultrasound and a higher penetration than confocal microcopy. Functional extensions are also possible, i.e., flow, birefringence or spectroscopic measurements with high spatial resolution. In ophthalmology, OCT is ...
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  2. About Thomas M. Jørgensen

    Thomas M. Jørgensen

    Thomas M. Jørgensen is a Senior Researcher at DTU Fotonik, Department of Photonics Engineering at the Technical University of Denmark (DTU).