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    1. Mentioned In 102 Articles

    2. ADVANCED OCT ANALYSIS OF BIOPSY PROVEN VITREORETINAL LYMPHOMA: OCT findings in vitreo-retinal lymphoma

      ADVANCED OCT ANALYSIS OF BIOPSY PROVEN VITREORETINAL LYMPHOMA: OCT findings in vitreo-retinal lymphoma
      Importance: Although the diagnosis of vitreoretinal lymphoma (VRL) can be challenging, early detection is critical for visual prognosis. Objective: To analyze the spectrum of optical coherence tomography (OCT) findings in patients with biopsy-proven VRL and correlate these features with clinical parameters. Design: Retrospective cross-sectional study SETTING: Multicenter chart review from 13 retina, uveitis and ocular oncology clinics worldwide over an 11-year period (2008-2019). Participants: Patients with a diagnosis of biopsy-proven ...
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    3. Pars Plana Vitrectomy for Idiopathic Epiretinal Membrane: Optical Coherence Tomography Biomarkers of Visual Outcomes in 322 Eyes

      Pars Plana Vitrectomy for Idiopathic Epiretinal Membrane: Optical Coherence Tomography Biomarkers of Visual Outcomes in 322 Eyes
      Objective: To investigate optical coherence tomography (OCT)-based biomarkers of visual acuity (VA) in eyes with idiopathic epiretinal membranes (ERM) undergoing surgical intervention. Purpose: To assess surgical outcomes of pars plana vitrectomy (PPV) and membrane peel (MP) surgery in eyes with idiopathic ERM and identify potential imaging-based biomarkers of vision outcomes. Methods: Retrospective, consecutive case series of eyes with idiopathic ERM that underwent PPV and MP surgery between 1/1 ...
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    4. The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies

      The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies
      Objective: To update the consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results, thus revising the previously published Advised Protocol for OCT Study Terminology and Elements (APOSTEL) recommendations. Methods: To identify studies reporting quantitative OCT results, we performed a PubMed search for the terms "quantitative" and "optical coherence tomography" from 2015 to 2017. Corresponding authors of the identified publications were invited to provide feedback on the initial ...
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    5. Comparison of two spectral-domain optical coherence tomography scan modes for measuring retinal vessel diameter

      Comparison of two spectral-domain optical coherence tomography scan modes for measuring retinal vessel diameter
      Purpose : To assess the agreement between Line 3-5 raster scan mode and circular scan mode for measuring retinal vessel diameter, and to analyze the influence of scanning distance on retinal vessel diameter and agreement. Methods : 79 healthy participants (79 eyes) were scanned with two modes. The scanning distance was defined as the distance from the center of the optic disc to the intersection of the blood vessel and the scan ...
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    6. Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and Optical Coherence Tomography Analysis

      Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and Optical Coherence Tomography Analysis
      Purpose: To assess visual acuity (VA) outcomes of epiretinal membrane (ERM) surgery following primary rhegmatogenous retinal detachment (RD) repair. Design: Retrospective, consecutive case series. Subjects: Eyes undergoing pars plana vitrectomy (PPV) with membrane peel (MP) surgery for ERM following primary RD repair (PPV with or without scleral buckle (SB) and gas tamponade). Methods: Retrospective chart review from 2015 to 2018. A previously described ERM grading scale was utilized for OCT ...
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    7. Retinal Optical Coherence Tomography Metrics are Unchanged in Verubecestat Alzheimer's Disease Clinical Trial but Correlate with Baseline Regional Brain Atrophy

      Retinal Optical Coherence Tomography Metrics are Unchanged in Verubecestat Alzheimer's Disease Clinical Trial but Correlate with Baseline Regional Brain Atrophy
      Background: We performed exploratory analyses of retinal thickness data from a clinical trial of the APP cleaving enzyme (BACE) inhibitor verubecestat in patients with Alzheimer's disease (AD). Objective: To evaluate: 1) possible retinal thickness changes following BACE inhibition; and 2) possible association between retinal thickness and brain atrophy. Methods: Retinal thickness was measured using spectral-domain optical coherence tomography in a 78-week randomized placebo-controlled trial of verubecestat in 1,785 ...
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    8. A pilot exploration using optical coherence tomography angiography analysis of capillary vascular density and foveal avascular zone for the diagnosis of uveal melanoma

      A pilot exploration using optical coherence tomography angiography analysis of capillary vascular density and foveal avascular zone for the diagnosis of uveal melanoma
      Dear Editor, Choroidal melanoma is a rare malignancy, and in one study from the United Kingdom, up to 30% of patients referred by the general ophthalmologist to an ocular oncology center were misdiagnosed. [1] Later, the mnemonic To find small ocular melanoma using helpful hints daily [2] was established to aid in the detection of this malignancy at an early point. With the rapid advancements in ocular imaging technology, quantifiable ...
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    9. Overhead Mounted Optical Coherence Tomography in Childhood Glaucoma Evaluation

      Overhead Mounted Optical Coherence Tomography in Childhood Glaucoma Evaluation
      Prcis: Overhead mounted spectral-domain optical coherence tomography enables high quality imaging of the optic nerve and macula in childhood glaucoma and is particularly useful when standard tabletop optical coherence tomography has failed or is not possible. Purpose: Tabletop optical coherence tomography, integral to adult glaucoma management, can be limited in childhood glaucoma patients due to young age, poor cooperation, and/or technical challenges. To address these imaging difficulties, we determined ...
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    10. Wide-Field (15 × 9 mm) Swept-Source Optical Coherence Tomography Angiography Following Plaque Radiotherapy of Choroidal Melanoma: An Analysis of 105 eyes

      Wide-Field (15 × 9 mm) Swept-Source Optical Coherence Tomography Angiography Following Plaque Radiotherapy of Choroidal Melanoma: An Analysis of 105 eyes
      Purpose: The aim of this study was to evaluate retinal microvascular abnormalities following plaque radiotherapy of choroidal melanoma (CM) using wide-field swept-source optical coherence tomography angiography (OCTA). Design: Single-centre retrospective review. Methods: Retrospective case series of 105 CM patients treated with I-125 plaque radiotherapy and imaged with wide-field (15 9 mm) SS-OCTA from March 2018 to August 2018 at the Ocular Oncology Service, Wills Eye Hospital (Philadelphia, PA). Results: At ...
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    11. SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FEATURES OF VITREORETINAL LYMPHOMA IN 55 EYES

      SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FEATURES OF VITREORETINAL LYMPHOMA IN 55 EYES
      Purpose: To evaluate spectral domain optical coherence tomography (SD- OCT ) features of vitreoretinal lymphoma (VRL). Methods: Review of records and SD- OCT images of vitreoretinal lymphoma evaluated at Ocular Oncology Service, Wills Eye Hospital between July 1, 2000, and April 1, 2019. Results: There were 55 eyes of 32 patients included. At presentation, SD- OCT features included vitreous opacities (n = 36, 65%), preretinal deposits (n = 7, 13%), intraretinal deposits (n ...
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    12. Utility of Optical Coherence Tomography (OCT) in Centers For Medicare and Medicaid Services (CMS)-defined Severe Glaucoma Patients

      Utility of Optical Coherence Tomography (OCT) in Centers For Medicare and Medicaid Services (CMS)-defined Severe Glaucoma Patients
      Precis: Patients with Centers For Medicare and Medicaid Services (CMS)-defined severe glaucoma often have clinically useful remaining retinal nerve fiber layer (RNFL), suggesting that structurally based rather than functionally based criteria would be more appropriate to use as guidelines for the utilization of optical coherence tomography (OCT) imaging. Purpose: RNFL OCT in glaucomatous eyes with advanced structural damage can reach a floor after which there is no further detectable ...
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    13. Optical Coherence Tomography Monitoring in a Patient With Retinoblastoma

      Optical Coherence Tomography Monitoring in a Patient With Retinoblastoma
      A 17-month-old girl with group B retinoblastoma in her right eye developed recurrence of a parafoveal tumor ( Figure , A) after 6 cycles of intravenous chemotherapy. Despite treatment with indocyanine greenenhanced transpupillary thermotherapy, optical coherence tomography (vertical orientation) demonstrated continued tumor growth toward the foveola. The patient was subsequently treated with 2 cycles of intra-arterial chemotherapy, after which complete tumor regression to a flat scar was documented clinically and by optical ...
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    14. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DETECTS SUBCLINICAL RADIAL PERIPAPILLARY CAPILLARY DENSITY REDUCTION AFTER PLAQUE RADIOTHERAPY FOR CHOROIDAL MELANOMA

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DETECTS SUBCLINICAL RADIAL PERIPAPILLARY CAPILLARY DENSITY REDUCTION AFTER PLAQUE RADIOTHERAPY FOR CHOROIDAL MELANOMA
      Purpose: To evaluate radial peripapillary capillary density (RPCD) in irradiated eyes without radiation papillopathy clinically. Methods: Patients treated with plaque radiotherapy for unilateral choroidal melanoma without radiation papillopathy clinically received optical coherence tomography and optical coherence tomography angiography imaging at 12- to 24-month follow-up. Comparison of RPCD globally and meridian closest to plaque and meridian farthest to plaque of irradiated versus nonirradiated eyes was performed. Results: Mean age was 55 ...
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    15. Utility of Optical Coherence Tomography (OCT) in Centers for Medicare and Medicaid Services (CMS) Defined Severe Glaucoma Patients

      Utility of Optical Coherence Tomography (OCT) in Centers for Medicare and Medicaid Services (CMS) Defined Severe Glaucoma Patients
      Prcis: Patients with CMS defined severe glaucoma often have clinically useful remaining RNFL, suggesting that structurally-based rather than functionally-based criteria would be more appropriate to use as guidelines for the utilization of OCT imaging. Purpose: RNFL OCT in glaucomatous eyes with advanced structural damage can reach a floor after which there is no further detectable thinning of RNFL. Insurers are considering limiting coverage for OCT in severe stage glaucoma defined ...
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  2. About Thomas Jefferson University

    Thomas Jefferson University

    Thomas Jefferson University is an independent medical school, health professions and medical research institution. Founded in 1824, it is located in Center City, Philadelphia, Pennsylvania. The university takes an active role in medical research.  It began as Jefferson Medical College in 1824. On July 1, 1969 the institution officially became Thomas Jefferson University.  The university is made up of three colleges:  Jefferson Medical College, Jefferson College of Graduate Studies, Jefferson College of Health Professions".