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1. Mentioned In 87 Articles
2. Jefferson and Wills Eye Launch World's First Center Focused on Connections Between the Eye and the Brain
  
  Explore PR Newswire May 10 2019 Neurology , Ophthalmology
  
  ...ry careers, and discovering new treatments to define the future of care. Jefferson (Philadelphia University + Thomas Jefferson University), home of Sidney Kimmel Medical College, dates back to 1824 and today comprises 10...
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3. Peripapillary versus macular combined hamartoma of the retina and retinal pigment epithelium: Imaging characteristics
  
  Explore American Journal of Ophthalmology Jan 26 2019 Ophthalmology
  
  Purpose To compare clinical, optical coherence tomography (OCT), and fundus autofluorescence (FAF) characteristics of peripapillary versus (vs.) macular variants of combined hamartoma of the retina and retinal pigment epithelium (combined hamartoma). Design Retrospective observational, comparative case series Methods:Setting Multicentre collaborative study Study Population 50 eyes with a clinical diagnosis of combined hamartoma Observational Analysis A comparative analysis of color fundus photographs (CFPs), OCT and FAF was performed for peripapillary ...
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  Mentions: Columbia University Thomas Jefferson University Lawrence A. Yannuzzi
4. Optical Coherence Tomography to Assess Anatomic Changes in Recipients of Electronic Retinal Implants Getting Closer to the Promised Land of Sight for All
  
  Explore The JAMA Network Jan 4 2019 Ophthalmology
  
  They came to Bethsaida. Some people brought a blind man to him and begged him to touch him. 23 He took the blind man by the hand and led him out of the village; and when he had put saliva on his eyes and laid his hands on him, he asked him, Can you see anything? 24 And the man looked up and said, I can see people, but they ...
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  Mentions: Thomas Jefferson University
5. Microvascular Capillary Plexus Findings of Commotio Retinae on Optical Coherence Tomography Angiography
  
  Explore Karger Publishers Dec 4 2018 Ophthalmology
  
  Optical coherence tomography (OCT) and histopathology features of commotio retinae (CR) have been established, but alterations of the microvascular macular capillary plexus on OCT angiography (OCTA) has not been previously studied. We present a 46-year-old man who sustained a tennis ball injury to the right eye with visual acuity reduction to 20/30 and grey-white deep macular discoloration, suggestive of CR. Spectral-domain OCT (SD-OCT) showed increased reflectivity and thickness of ...
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  Mentions: Thomas Jefferson University Carol L. Shields
6. Optical coherence tomography of iris mammillations
  
  Explore casereports.bmj.com Aug 29 2018 Ophthalmology
  
  A 10-year-old girl presented with blurred vision of 2 months. Uncorrected visual acuity was 20/20 in both eyes (OU). Refraction revealed 0.75 diopters of astigmatism OU. Visual blur was related to a moderate convergence insufficiency. The superior 90% of the left iris was darkly pigmented and velvety in consistency with regularly spaced protuberances (mammillations) (figure 1).
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  Mentions: Thomas Jefferson University Carol L. Shields
7. Hand-held optical coherence tomography monitoring of submillimeter retinoblastoma treated with indocyanine green-enhanced transpupillary therapy
  
  Explore meajo.org Aug 21 2018 Ophthalmology
  
  Over recent years, hand-held optical coherence tomography (HH-OCT) has become critical for retinoblastoma diagnosis and management. We report precise HH-OCT findings in a case of sub-millimeter retinoblastoma treated with foveal-sparing indocyanine green-enhanced transpupillary thermotherapy (ICG-TTT). A 2-month-old Caucasian female with bilateral Group B retinoblastoma showed two recurrent macular tumors in the right eye, demonstrating 88 m and 37 m of growth to 344 m and 413 m in thickness, respectively ...
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  Mentions: Thomas Jefferson University Carol L. Shields
8. Iris microhemangiomatosis: Clinical, fluorescein angiography, and optical coherence tomography angiography in 14 consecutive patients
  
  Explore American Journal of Ophthalmology Aug 14 2018 Ophthalmology
  
  Purpose To describe the clinical and imaging findings and treatment options in a series of patients with iris microhemangiomatosis. Design: Retrospective observational case series. Methods Setting : Single institution. Study Population : Twenty-two eyes of 14 consecutive patients with iris microhemangiomatosis were reviewed. Observation Procedures : Clinical examination and slit lamp photography were performed on every patient. Anterior segment optical coherence tomography (AS-OCT), anterior segment optical coherence tomography angiography (AS-OCTA), anterior segment intravenous ...
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  Mentions: Thomas Jefferson University Jerry A. Shields Carol L. Shields
9. MULTIMODAL IMAGING OF MACULAR CHOROIDAL MACROVESSEL: A REPORT OF TWO CASES
  
  Explore LWW Online Jul 21 2018 Ophthalmology
  
  Purpose: To report two cases of macular choroidal macrovessel with description of multimodal imaging and review of published cases. Methods: Medical and imaging records were retrospectively reviewed. A literature review was performed to identify other cases of macular choroidal macrovessel published between 1990 and 2018. Results: There were 2 patients referred for evaluation of a potential choroidal tumor , including a 55-year-old white woman with no visual symptoms and a 68-year-old ...
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  Mentions: Thomas Jefferson University Carol L. Shields
10. Optical Coherence Tomography of Small Retinoblastoma
  
  Explore Asia-Pacific Academy of Ophthalmology Jul 14 2018 Ophthalmology
  
  Purpose: To investigate hand-held optical coherence tomography (HHOCT) characteristics of small (1 mm thickness) retinoblastoma. Design: Retrospective observational case series. Methods: Patient and tumor data were extracted from the medical record and analyzed along with HH-OCT scans. Determination of tumor layer of origin was performed using a layer-by-layer analysis of HH-OCT data and specific HH-OCTrelated features were described. Results: There were 20 sub-millimeter retinoblastomas from 16 eyes of 15 patients ...
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  Mentions: Thomas Jefferson University Carol L. Shields
11. Submillimeter retinoblastoma monitoring following transpupillary thermotherapy using hand-held optical coherence tomography
  
  Explore journalretinavitreous.biomedcentral.com Mar 4 2018 Ophthalmology
  
  Background Precise, submillimeter visualization of retinal microstructures is useful for treatment monitoring of retinoblastoma. Herein, we report the use of hand-held optical coherence tomography (HH-OCT) to document a nearly-invisible retinoblastoma and monitor tumor response to transpupillary thermotherapy (TTT). Case presentation A 3-week-old boy was diagnosed with unilateral familial retinoblastoma in the left eye, classified as group B, and treated with intravenous chemoreduction. At 13-month follow-up, the tumor in the left ...
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  Mentions: Thomas Jefferson University Carol L. Shields
12. HAND-HELD OPTICAL COHERENCE TOMOGRAPHY MONITORING OF CHEMORESISTANT RETINOBLASTOMA
  
  Explore LWW Online Feb 27 2018 Ophthalmology
  
  Purpose: Retinoblastoma (Rb) is a potentially fatal intraocular malignancy in children, and hand-held optical coherence tomography (HH-OCT) can assist in submillimeter detection and monitoring after treatment of Rb. Retinoblastoma located in the macula, or those with chemoresistance, can be among the most difficult to manage. We describe HH-OCT features in a case of chemoresistant macular Rb that eventually responded to plaque radiotherapy after failing intravenous chemotherapy and intraarterial chemotherapy. Methods ...
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  Mentions: Thomas Jefferson University Carol L. Shields
13. Optical Coherence Tomography: Clinicopathologic Correlations - The 2016 Gordon K. Klintworth Lecture
  
  Explore Karger Publishers Dec 16 2017 Ophthalmology
  
  Background/Aims: Spectral domain optical coherence tomography (SD-OCT) has become a mainstay of ophthalmic practice that has revolutionized the assessment and treatment of a variety of ocular disorders. Studies that directly correlate SD-OCT and histopathology are necessary to demonstrate the actual nature of the retinal pathology responsible for the images that resemble histologic sections, but are generated by mathematical algorithms. Methods: Careful correlative light microscopy was performed on a small ...
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  Mentions: Thomas Jefferson University
14. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS OF DEEP CAPILLARY PLEXUS MICROISCHEMIA AFTER INTRAVENOUS CHEMOTHERAPY FOR RETINOBLASTOMA
  
  Explore LWW Online Dec 2 2017 Ophthalmology
  
  Purpose: To study changes in the foveal microvascular anatomy using optical coherence tomography angiography (OCTA) after intravenous chemotherapy (IVC) for retinoblastoma (RB). Methods: A retrospective comparative casecontrol series included 10 age-matched normal eyes with no documented ocular pathology (control), 10 fellow eyes of patients with unilateral RB treated with IVC (RB fellow), and 10 eyes with extramacular RB in patients with bilateral RB treated with IVC (RB tumor). All eyes ...
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  Mentions: Thomas Jefferson University Carol L. Shields
15. Parafoveolar retinoblastoma regression with foveal preservation following intra-arterial chemotherapy documented on hand-held optical coherence tomography in a newborn
  
  Explore journalretinavitreous.biomedcentral.com Nov 18 2017 Ophthalmology
  
  Background Optical coherence tomography (OCT) has become an invaluable tool in retinoblastoma management, providing submillimeter visualization of tumor control following treatment. Herein, we document OCT-detection of a subtle tumor recurrence, allowing early intervention and achieving foveal microanatomy preservation. Case presentation A 3-week-old girl was diagnosed with bilateral familial retinoblastoma, classified as group D in the right eye (OD) and group B in the left eye (OS), and treated with intravenous ...
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  Mentions: Thomas Jefferson University Carol L. Shields
16. En Face Optical Coherence Tomography of Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis
  
  Explore The JAMA Network Nov 15 2017 Ophthalmology
  
  A woman in her 60s presented with 2 months of blurred vision in the left eye, with visual acuity of 20/40. Examination of the left ocular fundus revealed spokelike foveal cysts. Fluorescein angiography showed no foveal leakage. En face optical coherence tomography (Optovue Inc) in the left eye revealed stellate hyporeflectivity ( Figure , A). A retinal cross-section scan revealed foveomacular retinoschisis involving the outer plexiform layer ( Figure , B). The fellow ...
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  Mentions: Optovue Thomas Jefferson University Drexel University
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