1. Thomas E. Milner

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    1. Mentioned In 103 Articles

    2. Virtual Histology Optical Coherence Tomography Imaging of Orbital Rotational Atherectomy for Calcified Peripheral Arterial Disease

      Explore Invasive Cardiology Cardiology
      Virtual Histology Optical Coherence Tomography Imaging of Orbital Rotational Atherectomy for Calcified Peripheral Arterial Disease
      A 72-year-old man with critical limb ischemia of the right lower extremity was referred for revascularization. His peripheral angiography showed severely calcified total occlusions of the right posterior tibial artery, peroneal arteries, and dorsalis pedis, with severe stenosis of the anterior tibial artery with collaterals (Figures 1A-1D). In order to assess the vascular effects of rotational orbital atherectomy, we performed intravascular imaging with virtual histology intravascular optical coherence tomography (VH-IVOCT ...
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      Mentions: Thomas E. Milner Marc D. Feldman University of Texas at Austin

    3. Scattering Angle Resolved Optical Coherence Tomography Detects Early Changes in 3xTg Alzheimer's Disease Mouse Model

      Explore TVST Journal Ophthalmology
      Scattering Angle Resolved Optical Coherence Tomography Detects Early Changes in 3xTg Alzheimer's Disease Mouse Model
      Purpose : Clinical intensity-based optical coherence tomographic retinal imaging is unable to resolve some of the earliest changes to Alzheimer's disease (AD) neurons. The aim of this pilot study was to demonstrate that scattering-angle-resolved optical coherence tomography (SAR - OCT), which is sensitive to changes in light scattering angle, is a candidate retinal imaging modality for early AD detection. SAR-OCT signal data may be sensitive to changes in intracellular constituent morphology ...
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      Mentions: Massoud Motamedi Thomas E. Milner University of Texas at Austin

    5. Apparatus and methods for optical coherence tomography and two-photon luminescence imaging

      Explore uspto.gov Patents
      Apparatus and methods for optical coherence tomography and two-photon luminescence imaging
      Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (OCT-TPL) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo.
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      Mentions: Thomas E. Milner Marc D. Feldman University of Texas at Austin

    6. Assessment of Vascular Patency and Inflammation with Intravascular Optical Coherence Tomography in Patients with Superficial Femoral Artery Disease Treated with Zilver PTX Stents

      Explore ScienceDirect Cardiology
      Assessment of Vascular Patency and Inflammation with Intravascular Optical Coherence Tomography in Patients with Superficial Femoral Artery Disease Treated with Zilver PTX Stents
      Purpose Zilver PTX nitinol self-expanding drug-eluting stent with paclitaxel coating is effective for treatment of superficial femoral artery (SFA) disease. However, as with any stent, it induces a measure of vascular inflammatory response. The current clinical trial (NCT02734836) aimed to assess vascular patency, remodeling, and inflammatory markers with intravascular optical coherence tomography (OCT) in patients with SFA disease treated with Zilver PTX stents. Methods Serial OCT examinations were performed in ...
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      Mentions: Leiden University Thomas E. Milner Marc D. Feldman

    7. Laser brain cancer surgery in a xenograft model guided by optical coherence tomography

      Explore Theranostics
      Laser brain cancer surgery in a xenograft model guided by optical coherence tomography
      Higher precision surgical devices are needed for tumor resections near critical brain structures. The goal of this study is to demonstrate feasibility of a system capable of precise and bloodless tumor ablation. An image-guided laser surgical system is presented for excision of brain tumors in vivo in a murine xenograft model. The system combines optical coherence tomography (OCT) guidance with surgical lasers for high-precision tumor ablation (Er:YAG) and microcirculation ...
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      Mentions: Thomas E. Milner Marc D. Feldman University of Texas at Austin

    8. Scattering-Angle-Resolved Optical Coherence Tomography of a Hypoxic Mouse Retina Model

      Explore SAGE Journals Ophthalmology
      Scattering-Angle-Resolved Optical Coherence Tomography of a Hypoxic Mouse Retina Model
      Several studies have noted a correlation between retinal degeneration and traumatic encephalopathy (TE) making the retina a leading candidate for detection and assessment. Scattering-angle-resolved optical coherence tomography (SAR-OCT) is a candidate imaging modality to detect sub-resolution changes in retinal microstructure. SAR-OCT images of murine retinas that experience a hypoxic insult euthanasia by isoflurane overdoseare presented. A total of 4 SAR-OCT measurement parameters are reported in 6 longitudinal experiments: blood flow ...
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      Mentions: Thomas E. Milner University of Texas at Austin

    9. OCT-IVUS catheter for concurrent luminal imaging

      Explore uspto.gov Cardiology , Patents , Probes
      OCT-IVUS catheter for concurrent luminal imaging
      The invention relates to an apparatus for in vivo imaging. More specifically, the present invention relates to a catheter that incorporates an Optical Coherence Tomography (OCT) system and an Intravascular Ultrasound ("IVUS) system for concurrent imaging of luminal systems, such as imaging the vasculature system, including, without limitation, cardiac vasculature, peripheral vasculature and neural vasculature.
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      Mentions: Thomas E. Milner Paul Castella University of Texas at Austin

    10. Design Considerations for Murine Retinal Imaging Using Scattering Angle Resolved Optical Coherence Tomography

      Explore MDPI Open Access Journals Platform Ophthalmology
      Design Considerations for Murine Retinal Imaging Using Scattering Angle Resolved Optical Coherence Tomography
      Optical coherence tomography (OCT), an optical imaging approach enabling cross-sectional analysis of turbid samples, is routinely used for retinal imaging in human and animal models of diseases affecting the retina. Scattering angle resolved (SAR-)OCT has previously been demonstrated as offering additional contrast in human studies, but no SAR-OCT system has been reported in detail for imaging the retinas of mice. An optical model of a mouse eye was designed ...
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      Mentions: Thomas E. Milner University of Texas at Austin

    12. Understanding and improving optical coherence tomography imaging depth in selective laser sintering nylon 12 parts and powder

      Explore SPIE Digital Library NDE/NDT
      Understanding and improving optical coherence tomography imaging depth in selective laser sintering nylon 12 parts and powder
      Optical coherence tomography (OCT) has shown promise as a process sensor in selective laser sintering (SLS) due to its ability to yield depth-resolved data not attainable with conventional sensors. However, OCT images of nylon 12 powder and nylon 12 components fabricated via SLS contain artifacts that have not been previously investigated in the literature. A better understanding of light interactions with SLS powder and components is foundational for further research ...
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      Mentions: Thomas E. Milner University of Texas at Austin

    13. In situ process monitoring in selective laser sintering using optical coherence tomography

      Explore SPIE Digital Library
      In situ process monitoring in selective laser sintering using optical coherence tomography
      Selective laser sintering (SLS) is an efficient process in additive manufacturing that enables rapid part production from computer-based designs. However, SLS is limited by its notable lack ofin situprocess monitoring when compared with other manufacturing processes. We report the incorporation of optical coherence tomography (OCT) into an SLS system in detail and demonstrate access to surface and subsurface features. Video frame rate cross-sectional imaging reveals areas of sintering uniformity and ...
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      Mentions: Thomas E. Milner University of Texas at Austin

    15. Optical coherence tomography image-guided smart laser knife for surgery

      Explore Wiley Online Library
      Optical coherence tomography image-guided smart laser knife for surgery
      Background and Objective Surgical oncology can benefit from specialized tools that enhance imaging and enable precise cutting and removal of tissue without damage to adjacent structures. The combination of high-resolution, fast optical coherence tomography (OCT) co-aligned with a nanosecond pulsed thulium (Tm) laser offers advantages over conventional surgical laser systems. Tm lasers provide superior beam quality, high volumetric tissue removal rates with minimal residual thermal footprint in tissue, enabling a ...
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      Mentions: Thomas E. Milner University of Texas at Austin

    16. Apparatus and methods for identifying and evaluating bright spot indications observed through optical coherence tomography

      Explore uspto.gov Patents
      Apparatus and methods for identifying and evaluating bright spot indications observed through optical coherence tomography
      Exemplary embodiments of the present disclosure include apparatus and methods for identifying bright spot indications observed through optical coherence tomography. The indications can be evaluated, for example, to link risk factors or other conditions to clinically relevant outcomes
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      Mentions: Thomas E. Milner Marc D. Feldman University of Texas at Austin
    17. 1-15 of 103 1 2 3 4 5 6 7 »
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  4. About Thomas E. Milner

    Thomas E. Milner

    Thomas E. Milner, Ph.D, is an Associate Professor at the University of Texas Biomedical Engineering Department, and co-founder of CardioSpectra acquired by Volcano. Research Focus: Optical-based therapeutics and diagnostic imaging, biomedical fiber sensors, infrared imaging radiometry.

  5. Related Topics

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      88 articles also mentioned University of Texas at Austin
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    4. Speckle noise reduction algorithm for optical coherence tomography based on interval type II fuzzy set
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    5. Detection of multiple scattering in optical coherence tomography using the spatial distribution of Stokes vectors
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  6. Quotes

    1. OCT is one of the most promising and exciting medical imaging technologies available today...The detail of information OCT can provide is simply astonishing and will continue to impact not only cardiology but other medical disciplines, such as ophthalmology.
      In Researchers Receive $300,000 Award to Advance Technology With Potential to Predict Heart Attacks