1. The Ohio State University

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    1. Mentioned In 43 Articles

    2. Novel High-Resolution Imaging Using ANTERION Optical Coherence Tomography to Assess Fluid Reservoir Change in Scleral Lens Periphery

      Novel High-Resolution Imaging Using ANTERION Optical Coherence Tomography to Assess Fluid Reservoir Change in Scleral Lens Periphery
      Objectives: To assess scleral lens fluid reservoir (FR) change simultaneously in four quadrants with single acquisition using novel ANTERION anterior segment swept-source optical coherence tomography (SS-OCT). Methods: A prospective, observational, clinical study of 18 subjects (30 eyes) was performed on adults fitted with a scleral lens for ocular surface disease (n=8), irregular cornea/scar (n=7), and corneal ectasia (n=15). ANTERION anterior segment SS-OCT imaging was obtained at ...
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    3. Ohio State University Receives NIH Grant for Full Field OCT for Cellular Level Structural and Functional Retinal Imaging

      Ohio State University Receives NIH Grant for Full Field OCT for Cellular Level Structural and Functional Retinal Imaging
      ...ly determine whether the neurons are structurally intact but importantly are also exhibiting normal function. Ohio State University Received a 2022 NIH Grant for $548,978 for Full Field OCT for Cellular Level Structural ...
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    4. Preliminary Results of Noninvasive Ocular Rigidity in Diabetic Retinopathy Using Optical Coherence Tomography

      Preliminary Results of Noninvasive Ocular Rigidity in Diabetic Retinopathy Using Optical Coherence Tomography
      The pathologic mechanism of diabetic retinopathy is directly related to the underlying hyperglycemia associated with diabetes. Hyperglycemia causes non-enzymatic cross-linking of collagen fibrils which contributes mechanistically to tissue stiffening. However, investigations on diabetic retinopathy-associated alteration in ocular biomechanics remain scarce, especially in living human eyes. Ocular rigidity is classically defined as a measure of the change in intraocular pressure produced by a change in ocular volume. We recently implemented an ...
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    5. Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumors

      Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumors
      Currently, intraoperative tumor margin imaging is not routinely utilized in veterinary medicine. Optical coherence tomography (OCT) allows for real-time assessment of tissue morphology of 1-2 mm depth. The aims of this study were 1) to compare the histologic and OCT features of excised canine skin and subcutaneous specimens, and 2) to determine the diagnostic accuracy of OCT for surgical margin evaluation. The authors hypothesized that OCT imaging would correlate well ...
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    6. Indoor localization of hand-held OCT probe using visual odometry and real-time segmentation using deep learning

      Indoor localization of hand-held OCT probe using visual odometry and real-time segmentation using deep learning
      Objective: Optical coherence tomography (OCT) is an established medical imaging modality that has found widespread use due to its ability to visualize tissue structures at a high resolution. Currently, OCT hand-held imaging probes lack positional information, making it difficult or even impossible to link a specific image to the location it was originally obtained. In this study, we propose a camera-based localization method to track and record the scanner position ...
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    7. DEVELOPMENT OF PHASE DECORRELATION OPTICAL COHERENCE TOMOGRAPHY FOR ASSESSMENT OF THE OCULAR LENS AND CORNEA

      DEVELOPMENT OF PHASE DECORRELATION OPTICAL COHERENCE TOMOGRAPHY FOR ASSESSMENT OF THE OCULAR LENS AND CORNEA
      The human ocular system is tightly maintained in order to sharply focus images onto the retina. Our understanding of the ocular system has benefited from the study of biomechanical phenomena. For instance, the field has begun to understand a range of diseases as biomechanical in origin such as keratoconus, glaucoma, and myopia. This mechanical understanding of disease has led to the development of new treatments, primarily crosslinking, which directly address ...
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    8. Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma

      Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma
      The invasive, locally aggressive nature of feline injection-site sarcomas (FISS) pose a unique challenge for surgeons to obtain complete margins with surgical excision. Optical coherence tomography (OCT), an imaging technology that uses light waves to generate real-time views of tissue architecture, provides an emerging solution to this dilemma by allowing fast, high-resolution scanning of surgical margins. The purpose of this study was to use OCT to assess surgical margins of ...
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    9. Exploring optical coherence tomography imaging depth to differentiate tissues at surgical margins

      Exploring optical coherence tomography imaging depth to differentiate tissues at surgical margins
      Optical coherence tomography (OCT) is an imaging modality that provides real-time visualization of tissue microstructure. The goals of this study were to assess OCT image tissue depths (TD) with image processing, and other objective characteristics of tissue types at surgical margins in canine soft tissue sarcoma (STS). In this study, a single observer reviewed 248 images of four tissue types (sarcoma, skeletal muscle, adipose and fascia) collected from 24 dogs ...
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    10. Intraoperative assessment of canine soft tissue sarcoma by deep learning enhanced optical coherence tomography

      Intraoperative assessment of canine soft tissue sarcoma by deep learning enhanced optical coherence tomography
      Soft tissue sarcoma (STS) is a locally aggressive and infiltrative tumor in dogs. Surgical resection is the treatment of choice for local tumor control. Currently, post-operative pathology is performed for surgical margin assessment. Spectral-domain optical coherence tomography (OCT) has recently been evaluated for its value for surgical margin assessment in some tumor types in dogs. The purpose of this study was to develop an automatic diagnosis system that can assist ...
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    11. Using Endoscopic Optical Coherence Tomography to Detect and Treat Early-Stage Pancreatic Cancers

      Using Endoscopic Optical Coherence Tomography to Detect and Treat Early-Stage Pancreatic Cancers
      We developed a novel technology capable of detecting early-stage pancreatic cancers using high-resolution three-dimensional endoscopic optical coherence tomography (Endo-OCT), and treating them using high dose rate brachytherapy (HDR) under the Endo-OCT image guidance. This technology integrates our custom-built ultra-high resolution endoscopic three-dimensional OCT diagnostic imaging device with a commercial high dose rate brachytherapy system (HDR), resulting in a compact, portable, easy-to-operate, and low-cost Endo-OCT image-guided high dose rate brachytherapy (OCT-IGHDR ...
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    12. Quantifying the Pattern of Retinal Vascular Orientation in Diabetic Retinopathy Using Optical Coherence Tomography Angiography

      Quantifying the Pattern of Retinal Vascular Orientation in Diabetic Retinopathy Using Optical Coherence Tomography Angiography
      Quantitative imaging using optical coherence tomography angiography (OCTA) could provide objective tools for the detection and characterization of diabetic retinopathy (DR). In this study, we developed a novel quantitative approach using OCTA images to delineate the vessel orientation pattern of a specific region of interest, which is an orientation distribution curve depicting the probability of vessels at each angle from 0 to 360 degrees. Three quantitative metrics including vessel preferred ...
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    13. The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumors

      The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumors
      Histopathologic surgical margin assessment in veterinary patients is an imprecise science with assessment limited to a small proportion of the surgical margin due to time and finances. Incomplete excision of canine mast cell tumors (MCTs) alters treatment recommendations and prognosis. Optical coherence tomography (OCT) is a novel imaging modality that has been reported in a single veterinary study for surgical margin assessment. Twenty‐five dogs with 34 MCTs were enrolled ...
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    14. 1-15 of 43 1 2 3 »
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  2. About The Ohio State University

    The Ohio State University

    The Ohio State University (OSU) is a public research university located in Columbus, Ohio. It was founded in 1870 as a land-grant university and is currently the second largest university campus in the United States. Ohio State is currently ranked by U.S. News & World Report as the best public university in Ohio, among the top 150 universities in the world, among the top 60 universities in the United States, and among the top 20 public universities in the United States. Ohio State has been officially designated as the flagship institution of the state's public system of higher education by the newly centralized University System of Ohio.