1. The Ohio State University

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    1. Mentioned In 37 Articles

    2. DEVELOPMENT OF PHASE DECORRELATION OPTICAL COHERENCE TOMOGRAPHY FOR ASSESSMENT OF THE OCULAR LENS AND CORNEA

      DEVELOPMENT OF PHASE DECORRELATION OPTICAL COHERENCE TOMOGRAPHY FOR ASSESSMENT OF THE OCULAR LENS AND CORNEA
      The human ocular system is tightly maintained in order to sharply focus images onto the retina. Our understanding of the ocular system has benefited from the study of biomechanical phenomena. For instance, the field has begun to understand a range of diseases as biomechanical in origin such as keratoconus, glaucoma, and myopia. This mechanical understanding of disease has led to the development of new treatments, primarily crosslinking, which directly address ...
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    3. Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma

      Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma
      The invasive, locally aggressive nature of feline injection-site sarcomas (FISS) pose a unique challenge for surgeons to obtain complete margins with surgical excision. Optical coherence tomography (OCT), an imaging technology that uses light waves to generate real-time views of tissue architecture, provides an emerging solution to this dilemma by allowing fast, high-resolution scanning of surgical margins. The purpose of this study was to use OCT to assess surgical margins of ...
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    4. Exploring optical coherence tomography imaging depth to differentiate tissues at surgical margins

      Exploring optical coherence tomography imaging depth to differentiate tissues at surgical margins
      Optical coherence tomography (OCT) is an imaging modality that provides real-time visualization of tissue microstructure. The goals of this study were to assess OCT image tissue depths (TD) with image processing, and other objective characteristics of tissue types at surgical margins in canine soft tissue sarcoma (STS). In this study, a single observer reviewed 248 images of four tissue types (sarcoma, skeletal muscle, adipose and fascia) collected from 24 dogs ...
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    5. Intraoperative assessment of canine soft tissue sarcoma by deep learning enhanced optical coherence tomography

      Intraoperative assessment of canine soft tissue sarcoma by deep learning enhanced optical coherence tomography
      Soft tissue sarcoma (STS) is a locally aggressive and infiltrative tumor in dogs. Surgical resection is the treatment of choice for local tumor control. Currently, post-operative pathology is performed for surgical margin assessment. Spectral-domain optical coherence tomography (OCT) has recently been evaluated for its value for surgical margin assessment in some tumor types in dogs. The purpose of this study was to develop an automatic diagnosis system that can assist ...
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    6. Using Endoscopic Optical Coherence Tomography to Detect and Treat Early-Stage Pancreatic Cancers

      Using Endoscopic Optical Coherence Tomography to Detect and Treat Early-Stage Pancreatic Cancers
      We developed a novel technology capable of detecting early-stage pancreatic cancers using high-resolution three-dimensional endoscopic optical coherence tomography (Endo-OCT), and treating them using high dose rate brachytherapy (HDR) under the Endo-OCT image guidance. This technology integrates our custom-built ultra-high resolution endoscopic three-dimensional OCT diagnostic imaging device with a commercial high dose rate brachytherapy system (HDR), resulting in a compact, portable, easy-to-operate, and low-cost Endo-OCT image-guided high dose rate brachytherapy (OCT-IGHDR ...
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    7. Quantifying the Pattern of Retinal Vascular Orientation in Diabetic Retinopathy Using Optical Coherence Tomography Angiography

      Quantifying the Pattern of Retinal Vascular Orientation in Diabetic Retinopathy Using Optical Coherence Tomography Angiography
      Quantitative imaging using optical coherence tomography angiography (OCTA) could provide objective tools for the detection and characterization of diabetic retinopathy (DR). In this study, we developed a novel quantitative approach using OCTA images to delineate the vessel orientation pattern of a specific region of interest, which is an orientation distribution curve depicting the probability of vessels at each angle from 0 to 360 degrees. Three quantitative metrics including vessel preferred ...
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    8. The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumors

      The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumors
      Histopathologic surgical margin assessment in veterinary patients is an imprecise science with assessment limited to a small proportion of the surgical margin due to time and finances. Incomplete excision of canine mast cell tumors (MCTs) alters treatment recommendations and prognosis. Optical coherence tomography (OCT) is a novel imaging modality that has been reported in a single veterinary study for surgical margin assessment. Twenty‐five dogs with 34 MCTs were enrolled ...
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    9. Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University

      Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University
      ...s. Nathan Doble and Stacey Choi in the College of Optometry/Department of Ophthalmology and Visual Science at The Ohio State University (OSU). The successful candidate will work within a highly collaborative research env...
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    10. Cone Photoreceptor Integrity assessed with Adaptive Optics Imaging after Laser-Pointer-Induced Retinal Injury

      Cone Photoreceptor Integrity assessed with Adaptive Optics Imaging after Laser-Pointer-Induced Retinal Injury
      Purpose: To examine the three-dimensional foveal cone photoreceptor structure in a patient who had suffered laser pointer induced retinal injury . Methods: Patient underwent standard fundus photography and clinical spectral domain optical coherence tomography (SD-OCT) imaging. High-resolution imaging was performed using an Adaptive Optics -OCT-Scanning Laser Ophthalmoscope (AO-OCT-SLO). Results: AO imaging revealed loss of inner and outer segments of cone photoreceptors while the anterior retinal layers appeared healthy. Analysis of cone ...
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    11. Near‐infrared imaging and optical coherence tomography for intraoperative visualization of tumors

      Near‐infrared imaging and optical coherence tomography for intraoperative visualization of tumors
      Surgical excision is the foundation of treatment for early‐stage solid tumors in man and companion animals. Complete excision with appropriate margins of surrounding tumor‐free tissue is crucial to survival. Intraoperative imaging allows real‐time visualization of tumors, assessment of surgical margins, and, potentially, lymph nodes and satellite metastatic lesions, allowing surgeons to perform complete tumor resections while sparing surrounding vital anatomic structures. This Review will focus on the ...
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    12. A marine biofilm flow cell for in situ screening marine fouling control coatings using optical coherence tomography

      A marine biofilm flow cell for in situ screening marine fouling control coatings using optical coherence tomography
      A novel fouling marine flow cell was designed and fitted with a clear plastic lid to allow real-time imaging of biofilms using optical coherence tomography (OCT). Marine biofilms were grown under controlled shear flow on coupons coated with 6 different biocidal antifouling coatings (SPC1, SPC2, SPC3, SPC4, CDP1 and CDP2, AkzoNobel) and one inert coating which contained no biocidal actives (NB-D) for 8 weeks. One set of coupons coated with ...
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    13. Inner Retinal Changes in Primary Open-Angle Glaucoma Revealed Through Adaptive Optics-Optical Coherence Tomography

      Inner Retinal Changes in Primary Open-Angle Glaucoma Revealed Through Adaptive Optics-Optical Coherence Tomography
      Purpose: To examine the microstructural changes in the inner nuclear layer (INL) and ganglion cell layer (GCL) in a primary open-angle glaucoma (POAG) subject at 2 timepoints, 4 months apart. Patients and Methods: This case-control study (1 POAG subject and 1 normal control) used the single cell, 3-dimensional volumetric imaging capability of an adaptive optics - optical coherence tomography -scanning laser ophthalmoscopy system to examine the inner retina. Results: At the ...
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    14. 1-15 of 37 1 2 3 »
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  2. About The Ohio State University

    The Ohio State University

    The Ohio State University (OSU) is a public research university located in Columbus, Ohio. It was founded in 1870 as a land-grant university and is currently the second largest university campus in the United States. Ohio State is currently ranked by U.S. News & World Report as the best public university in Ohio, among the top 150 universities in the world, among the top 60 universities in the United States, and among the top 20 public universities in the United States. Ohio State has been officially designated as the flagship institution of the state's public system of higher education by the newly centralized University System of Ohio.