1. The Chinese University of Hong Kong

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    1. Mentioned In 141 Articles

    2. Algorithm for Detection and Quantification of Hyperreflective Dots on Optical Coherence Tomography in Diabetic Macular Edema

      Algorithm for Detection and Quantification of Hyperreflective Dots on Optical Coherence Tomography in Diabetic Macular Edema
      Purpose: To develop an algorithm to detect and quantify hyperreflective dots (HRDs) on optical coherence tomography (OCT) in patients with diabetic macular edema (DME). Materials and Methods: Twenty OCTs (each OCT contains 128 b scans) from 20 patients diagnosed with DME were included in this study. Two types of HRDs, hard exudates and small HRDs (hypothesized to be activated microglia), were identified and labeled independently by two raters. An algorithm ...
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    3. A multi-task deep-learning system for assessment of diabetic macular ischemia on optical coherence tomography angiography images

      A multi-task deep-learning system for assessment of diabetic macular ischemia on optical coherence tomography angiography images
      Purpose: We aimed to develop and test a deep-learning (DL) system to perform image quality and diabetic macular ischemia (DMI) assessment on OCTA images. Methods: This study included 7,194 OCTA images with diabetes mellitus for training and primary validation, and 960 images from three independent datasets for external testing. A trinary classification for image quality assessment and presence or absence of DMI for DMI assessment were labelled on all ...
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    4. Semi-supervised generative adversarial networks for closed-angle detection on anterior segment optical coherence tomography images: an empirical study with a small training dataset

      Semi-supervised generative adversarial networks for closed-angle detection on anterior segment optical coherence tomography images: an empirical study with a small training dataset
      ...pervised training dataset collected from the Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong (JSIEC). The closed-angle was defined as iris-trabecular contact beyond th...
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    5. Endometrium optical coherence tomography (OCT) and histomorphometry in implantation window and their relationships with reproductive failure and implantation outcome

      Endometrium optical coherence tomography (OCT) and histomorphometry in implantation window and their relationships with reproductive failure and implantation outcome
      ...ntation outcomes. Study design, size, duration This was a prospective study conducted at teaching hospital of The Chinese University of Hong Kong from Jan 2018 to Dec 2019. 46 infertile women with or without recurrent mi...
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    6. Deep Learning-Based Optical Coherence Tomography and Optical Coherence Tomography Angiography Image Analysis: An Updated Summary

      Deep Learning-Based Optical Coherence Tomography and Optical Coherence Tomography Angiography Image Analysis: An Updated Summary
      Deep learning (DL) is a subset of artificial intelligence based on deep neural networks. It has made remarkable breakthroughs in medical imaging, particularly for image classification and pattern recognition. In ophthalmology, there are rising interests in applying DL methods to analyze optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images. Studies showed that OCT and OCTA image evaluation by DL algorithms achieved good performance for disease detection, prognosis ...
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    7. Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children

      Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
      Choroidal thickness is associated with many ocular conditions, interchangeability among different generations of optical coherence tomography is therefore important for both research purpose and clinical application. Hence, we compared choroidal thickness measurements between spectral-domain optical coherence tomography (SD-OCT) and swept-source optical coherence tomography (SS-OCT) in healthy paediatric eyes. A total of 114 children from the population-based Hong Kong Children Eye Study with mean age of 7.380.82 years were ...
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    8. Fundus Autofluorescence and Optical Coherence Tomography Characteristics in Different Stages of Central Serous Chorioretinopathy

      Fundus Autofluorescence and Optical Coherence Tomography Characteristics in Different Stages of Central Serous Chorioretinopathy
      Objective . To describe the morphological changes on fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT) imaging at different chronicity of central serous chorioretinopathy (CSC). Methods . This cross-sectional study included patients with CSC of different chronicity. Changes in FAF scans and morphological changes on SD-OCT were evaluated and compared at different stages of CSC. Results . Sixty-nine patients were enrolled in the study, with a mean age of 52.111.8 ...
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    9. Optical Coherence Tomography Angiography Compared with Multimodal Imaging for Diagnosing Neovascular Central Serous Chorioretinopathy

      Optical Coherence Tomography Angiography Compared with Multimodal Imaging for Diagnosing Neovascular Central Serous Chorioretinopathy
      Purpose: To assess the diagnostic accuracy of optical coherence tomography angiography (OCTA) compared with multimodal imaging for CNV in CSC eyes and to determine the features that predicted CNV. Design: Prospective cross-sectional study. Methods: Consecutive CSC patients were recruited from retina clinic. The reference standard for CNV was determined by interpretation of multimodal imaging with OCTA, structural OCT line scan, fluorescein angiography (FA), indocyanine green angiography (ICGA), ultra-widefield fundus photography ...
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    10. The association between attention-deficit/hyperactivity disorder and retinal nerve fiber/ganglion cell layer thickness measured by optical coherence tomography: a systematic review and meta-analysis

      The association between attention-deficit/hyperactivity disorder and retinal nerve fiber/ganglion cell layer thickness measured by optical coherence tomography: a systematic review and meta-analysis
      Purpose: Retinal nerve fiber/ganglion cell layer (RNFL/GCL) thickness measured using optical coherence tomography has been proposed as an ocular biomarker for children with attention-deficit/hyperactivity disorder (ADHD), but findings varied in different studies. This study aims to determine the association between RNFL/GCL thickness and ADHD in children by systematic review and meta-analysis. Methods: We performed a literature search in Embase, PubMed, Medline, Web of Science, and PsycINFO ...
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    11. Assessment of Generative Adversarial Networks for Synthetic Anterior Segment Optical Coherence Tomography Images in Closed-Angle Detection

      Assessment of Generative Adversarial Networks for Synthetic Anterior Segment Optical Coherence Tomography Images in Closed-Angle Detection
      ...ataset with AS-OCT images collected from the Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, synthesizing open- and closed-angle AS-OCT images. A visual Turing test w...
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    12. Determinants of peripapillary retinal nerve fiber layer’s grayscale value in normal eyes by spectral domain optical coherence tomography

      Determinants of peripapillary retinal nerve fiber layer’s grayscale value in normal eyes by spectral domain optical coherence tomography
      To determine and evaluate the distribution, variation, and determinants of peripapillary retinal nerve fiber layer (pRNFL) grayscale value with spectral-domain optical coherence tomography (SD-OCT) in normal eyes. In this cross-sectional study, three hundred ninety-seven normal eyes from 397 healthy Chinese adults aged 18-80 were consecutively recruited from a tertiary eye care center. An SD-OCT instrument took pRNFL imaging. We used a customized software to measure pRNFL parameters, including thickness and ...
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    13. Understanding Visual Acuity Outcomes After Retinal Detachment Repair by Assessing Photoreceptor Integrity on Spectral-Domain Optical Coherence Tomography

      Understanding Visual Acuity Outcomes After Retinal Detachment Repair by Assessing Photoreceptor Integrity on Spectral-Domain Optical Coherence Tomography
      The annual incidence of rhegmatogenous retinal detachment is approximately 18 to 22 per 100 000 population1,2and reported techniques for reattaching the retina include pneumatic retinopexy (PnR), scleral buckle, and pars plana vitrectomy (PPV). Recently, it has become increasingly common to repair a retinal detachment using vitrectomy and gas, given the higher anatomical success rate of this procedure. However, the Pneumatic Retinopexy Versus Vitrectomy for the Management of Primary Rhegmatogenous ...
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    14. Comparison of Two Novel Swept-Source OpticalCoherence Tomography Devices to A PartialCoherence Interferometry-Based Biometer

      Comparison of Two Novel Swept-Source OpticalCoherence Tomography Devices to A PartialCoherence Interferometry-Based Biometer
      Purpose To evaluate the repeatability and agreement of cornea and biometry measurements obtained with two swept-source optical coherence tomography (SSOCT) and a partial coherence interferometry-based device. METHODS This is a cross-sectional study. Forty-eight eyes of 48 patients had three consecutive measurements for ANTERION (Heidelberg Engineering, Germany), CASIAII (Tomey, Japan) and IOLMaster500 (Carl Zeiss Meditec, USA) on the same visit. Mean keratometry (Km), central cornea thickness (CCT), anterior chamber depth (ACD ...
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    15. Characterization of macular choroid in normal-tension glaucoma: a swept-source optical coherence tomography study

      Characterization of macular choroid in normal-tension glaucoma: a swept-source optical coherence tomography study
      Purpose: To investigate the features of the small-to-medium (choriocapillaris and Sattler's layer) and large (Haller's layer) sized vessel layers of the macular choroid in normal-tension glaucoma (NTG) patients using swept-source optical coherence tomography (SS-OCT). Methods: We conducted an observational cross-sectional study in 234 NTG eyes from 134 patients, and 203 normal eyes from 109 non-glaucomatous control subjects. We used Image J to segment the choroidal layer and then ...
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    16. Utilisation of poor-quality optical coherence tomography scans: adjustment algorithm from the Singapore Epidemiology of Eye Diseases (SEED) study

      Utilisation of poor-quality optical coherence tomography scans: adjustment algorithm from the Singapore Epidemiology of Eye Diseases (SEED) study
      Purpose To evaluate the effect of signal strength (SS) on optical coherence tomography (OCT) parameters, and devise an algorithm to adjust the effect, when acceptable SS cannot be obtained. Methods 5085 individuals (9582 eyes), aged 40 years from the Singapore Epidemiology of Eye Diseases population-based study were included. Everyone underwent a standardised ocular examination and imaging with Cirrus HD-OCT. Effect of SS was evaluated using multiple structural breaks linear mixed-effect ...
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  2. About The Chinese University of Hong Kong

    The Chinese University of Hong Kong

    The Chinese University of Hong Kong, commonly referred to as CUHK, is the second oldest university in Hong Kong; it is campus-based and also the only collegiate university in the territory. Despite its name, the Chinese University does not conduct its classes solely in Chinese. Both Chinese (Mandarin and Cantonese) and English are languages of instruction.

    The university's founders hoped that it would become the bridge that connects China and the West, and to combine tradition with modernity. The collegiate system CUHK comprises four colleges: Chung Chi College, New Asia College, United College, and Shaw College. All undergraduates are affiliated to one of them. Currently, five new colleges are to be established in the near future; namely Morningside College, S. H. Ho College, C. W. Chu College, Wu Yee Sun College and Lee Woo Sing College.

    Founded in 1963, The Chinese University of Hong Kong (CUHK) is a forward looking comprehensive research university with a global vision and a mission to combine tradition with modernity, and to bring together China and the West. CUHK teachers and students hail from all corners of the world. In 2007, we have more than 5,800 staff members, some 20,000 undergraduate and postgraduate students. Of these students, about 3,000 are from 45 countries and regions outside Hong Kong. The 100,000 alumni are connected through some 80 alumni associations both within and outside Hong Kong.