1. The Chinese University of Hong Kong

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    1. Mentioned In 107 Articles

    2. A 3D Deep Learning System for Detecting Referable Glaucoma Using Full OCT Macular Cube Scans

      A 3D Deep Learning System for Detecting Referable Glaucoma Using Full OCT Macular Cube Scans
      Purpose : The purpose of this study was to develop a 3D deep learning system from spectral domain optical coherence tomography (SD-OCT) macular cubes to differentiate between referable and nonreferable cases for glaucoma applied to real-world datasets to understand how this would affect the performance. Methods : There were 2805 Cirrus optical coherence tomography (OCT) macula volumes (Macula protocol 512 128) of 1095 eyes from 586 patients at a single site that ...
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    3. Clinically relevant factors associated with quantitative optical coherence tomography angiography metrics in deep capillary plexus in patients with diabetes

      Clinically relevant factors associated with quantitative optical coherence tomography angiography metrics in deep capillary plexus in patients with diabetes
      Background To test clinically relevant factors associated with quantitative artifact-free deep capillary plexus (DCP) metrics in patients with diabetes mellitus (DM). Methods 563 eligible eyes (221 with no diabetic retinopathy [DR], 135 with mild DR, 130 with moderate DR, and 77 with severe DR) from 334 subjects underwent optical coherence tomography-angiography (OCT-A) with a swept-source OCT (Triton DRI-OCT, Topcon, Inc., Tokyo, Japan). Strict criteria were applied to exclude from analysis ...
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    4. Longitudinal evaluation of immediate inflammatory responses after intravitreal AAV2 injection in normal rats by optical coherence tomography

      Longitudinal evaluation of immediate inflammatory responses after intravitreal AAV2 injection in normal rats by optical coherence tomography
      Gene therapy has been proposed as a feasible strategy for RGC survival and optic nerve regeneration. Some preclinical and clinical studies revealed intraocular inflammation after intravitreal injection of adeno-associated virus (AAV) by slit-lamp or indirect ophthalmoscope. Here we evaluate the longitudinal profile of immediate inflammatory responses after AAV2 injection in rat retina and vitreous body by optical coherence tomography (OCT). Adult Fischer F344 rats were intravitreally injected once with saline ...
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    5. Repeatability and Agreement of a Swept-Source Optical Coherence Tomography–Based Biometer IOLMaster 700 Versus a Scheimpflug Imaging–Based Biometer AL-Scan in Cataract Patients

      Repeatability and Agreement of a Swept-Source Optical Coherence Tomography–Based Biometer IOLMaster 700 Versus a Scheimpflug Imaging–Based Biometer AL-Scan in Cataract Patients
      Purpose: To compare the repeatability and agreement between a swept-source biometer and a Scheimpflug biometer in cataract patients. Methods: Three consecutive measurements were obtained using a swept-source biometer (IOLMaster 700) and a Scheimpflug biometer (AL-Scan) in 52 eyes of 52 patients. Keratometry, central corneal thickness (CCT), anterior chamber depth (ACD), axial length , and white-to-white (WTW) distance were recorded. Astigmatism values were transformed into vector components of J0 and J45. Intraoperator ...
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    6. Endometrium imaging using real-time rotational optical coherence tomography imaging system A pilot, prospective and ex-vivo study

      Endometrium imaging using real-time rotational optical coherence tomography imaging system A pilot, prospective and ex-vivo study
      This study aimed to evaluate a novel real-time rotational optical coherence tomography (OCT) imaging system (OCTIS) with a fiber-optic probe to look at endometrium and to correlate the OCTIS images with standard histology. OCT could obtain real-time images resembling histological examination. With recent development of customized probes, it allows OCT to be used in the field of gynecology . This is a pilot, prospective, ex-vivo and observational study. Women underwent hysterectomy ...
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    7. Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis

      Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis
      ...r training (60%), testing (20%), and primary validation (20%) from electronic medical and research records at the Chinese University of Hong Kong Eye Centre (Hong Kong, China) and the Hong Kong Eye Hospital (Hong Kong, C...
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    8. Unifying Structure Analysis and Surrogate-driven Function Regression for Glaucoma OCT Image Screening

      Unifying Structure Analysis and Surrogate-driven Function Regression for Glaucoma OCT Image Screening
      Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of automated methods has been developed based on OCT images for glaucoma study. In this paper, we present a novel framework to effectively classify glaucoma OCT images from normal ones. A semi-supervised learning strategy with smoothness assumption is ...
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    9. Retinal Optical Coherence Tomography Image Analysis (Textbook)

      Retinal Optical Coherence Tomography Image Analysis (Textbook)
      This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in the diagnosis and treatment of retinal diseases. Discussing the basic principles and the clinical applications of OCT imaging, OCT image preprocessing, as well as the automatic detection and quantitative analysis of retinal anatomy and pathology, it includes a wealth of clinical OCT images, and state-of-the-art research that applies novel image ...
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    10. Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders

      Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders
      Background/Aims To compensate the retinal nerve fibre layer (RNFL) thickness assessed by spectral-domain optical coherence tomography (SD-OCT) for anatomical confounders. Methods The Singapore Epidemiology of Eye Diseases is a population-based study, where 2698 eyes (1076 Chinese, 704 Malays and 918 Indians) with high-quality SD-OCT images from individuals without eye diseases were identified. Optic disc and macular cube scans were registered to determine the distance between fovea and optic disc ...
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    11. Optical Coherence Tomography Evaluation of Superficial Femoral Artery Directional Atherectomy

      Optical Coherence Tomography Evaluation of Superficial Femoral Artery Directional Atherectomy
      A 70-year-old man presented with lifestyle-limiting intermittent claudication (Rutherford stage III) affecting the right lower extremity. Physical examination of the right lower limb revealed weak distal pulses and a diminished ankle-brachial index of 0.6. Peripheral angiogram showed diffuse 80% stenosis over the right distal superficial femoral artery (SFA). The HawkOne directional atherectomy system (Medtronic Peripheral) was used to restore blood flow by removing plaque. After placing a 7 mm ...
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    12. Effect Of Optic Disk—Fovea Distance On Measurements Of Individual Macular Intraretinal Layers In Normal Subjects

      Effect Of Optic Disk—Fovea Distance On Measurements Of Individual Macular Intraretinal Layers In Normal Subjects
      Purpose: To investigate the effect of optic diskfovea distance (DFD) on measurements of macular intraretinal layers using spectral domain optical coherence tomography in normal subjects. Methods: One hundred and eighty-two eyes from 182 normal subjects were imaged using spectral domain optical coherence tomography. The average thicknesses of eight macular intraretinal layers were measured using an automatic segmentation algorithm. Partial correlation test and multiple regression analysis were used to determine the ...
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    13. Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment

      Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment
      Background and objective: Endometrial angiogenesis is a prerequisite for successful pregnancy. Optical coherence tomography (OCT) is a non-invasive physically optical imaging technique widely used in ophthalmology and cardiology. However, there is no study using OCT to evaluate endometrium. The aim of this study was to use OCT and traditionally histological methods to investigate endometrial vascularization in women undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment and to determine the association with ...
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    14. Layered Neointimal Pattern Secondary to Intraluminal Clot Organization in an Optical Coherence Tomography Longitudinal Study

      Layered Neointimal Pattern Secondary to Intraluminal Clot Organization in an Optical Coherence Tomography Longitudinal Study
      We present a case of follow-up optical coherence tomography (OCT) in a patient with non-obstructive intraluminal clot protrusion treated with medical therapy. The follow-up OCT scan showed layered neointimal changes similar to images observed in stent failure. A 37-year-old male presented with self-aborted anterior ST-elevation myocardial infarction. Urgent coronary angiogram showed thrombotic lesion in the proximal left anterior descending (LAD) artery (Figure 1). Multiple passes of aspiration thrombectomy retrieved a ...
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    15. Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects

      Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects
      Purpose To determine the influence of the optic discfovea distance (DFD) on the normative classifications based on thickness measurements of macular inner retinal layers with spectral-domain optical coherence tomography (OCT) in healthy subjects. Methods A total of 182 eyes from 182 healthy subjects were included (mean (SD) spherical equivalent 0.8 (1.9) dioptres). We performed macula and optic disc imaging with the Topcon 3D OCT 2000. The thickness of ...
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    16. Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis

      Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis
      Topic Optical coherence tomography (OCT) is a non-invasive tool to measure specific retinal layers in the eye. The relationship of retinal spectral domain-OCT (SD-OCT) measurements with Alzheimers Disease (AD) and mild cognitive impairment (MCI) remains unclear. Hence, we conducted a systematic review and meta-analysis to examine the SD-OCT measurements in AD and MCI. Clinical Relevance Current methods of diagnosing early AD are expensive and invasive. Retinal measurements of SD-OCT, which ...
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  2. About The Chinese University of Hong Kong

    The Chinese University of Hong Kong

    The Chinese University of Hong Kong, commonly referred to as CUHK, is the second oldest university in Hong Kong; it is campus-based and also the only collegiate university in the territory. Despite its name, the Chinese University does not conduct its classes solely in Chinese. Both Chinese (Mandarin and Cantonese) and English are languages of instruction.

    The university's founders hoped that it would become the bridge that connects China and the West, and to combine tradition with modernity. The collegiate system CUHK comprises four colleges: Chung Chi College, New Asia College, United College, and Shaw College. All undergraduates are affiliated to one of them. Currently, five new colleges are to be established in the near future; namely Morningside College, S. H. Ho College, C. W. Chu College, Wu Yee Sun College and Lee Woo Sing College.

    Founded in 1963, The Chinese University of Hong Kong (CUHK) is a forward looking comprehensive research university with a global vision and a mission to combine tradition with modernity, and to bring together China and the West. CUHK teachers and students hail from all corners of the world. In 2007, we have more than 5,800 staff members, some 20,000 undergraduate and postgraduate students. Of these students, about 3,000 are from 45 countries and regions outside Hong Kong. The 100,000 alumni are connected through some 80 alumni associations both within and outside Hong Kong.