1. Technical University of Munich

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    1. Mentioned In 29 Articles

    2. Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery

      Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery
      Needle segmentation is a fundamental step for needle reconstruction and image-guided surgery. Although there has been success stories in needle segmentation for non-microsurgeries, the methods cannot be directly extended to ophthalmic surgery due to the challenges bounded to required spatial resolution. As the ophthalmic surgery is performed by finer and smaller surgical instruments in micro-structural anatomies, specifically in retinal domains, difficulties are raised for delicate operation and sensitive perception. To ...
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    3. Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium

      Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium
      Background Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed ...
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    4. Optical coherence tomography in drug-eluting stent restenosis: a technique in need of a strategy

      Optical coherence tomography in drug-eluting stent restenosis: a technique in need of a strategy
      Despite the high anti-restenotic efficacy of contemporary percutaneous interventional techniques, a substantial number of patients who undergo percutaneous coronary intervention (PCI) still present with restenosis. Despite iterations of devices from plain balloon angioplasty to bare metal stenting (BMS) to drug-eluting stent (DES) therapy have granted a progressive decline in the rate of this complication, in-stent restenosis remains a critical issue encountered in clinical practice. Owing to the overall increase in ...
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    5. Markedly different tissue types on optical coherence tomography imaging in a patient with multiple lesion drug-eluting stent in-stent restenosis

      Markedly different tissue types on optical coherence tomography imaging in a patient with multiple lesion drug-eluting stent in-stent restenosis
      The treatment of in-stent restenosis after drug-eluting stent (DES) implantation remains a major clinical challenge. Optical coherence tomography (OCT) imaging at the time of presentation can provide important information on mechanical factors contributing to stent failure as well as on tissue characteristics of the in-stent neointimal tissue. We report a case of markedly different tissue typescharacterized by heterogeneous and homogeneous signal intensityobserved in a patient with multiple lesion DES in-stent ...
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    6. Malapposition: is it a major cause of stent thrombosis?

      Malapposition: is it a major cause of stent thrombosis?
      Stent thrombosis (ST) is a devastating complication associated with a high morbidity and mortality in patients who have undergone percutaneous coronary intervention (PCI) for coronary heart disease (CHD). In-hospital mortalities of patients suffering from ST have been reported to be as high as 7.9% for acute ST (AST; occurring 24 h after PCI) and subacute ST (SAST; occurring within 30 days after PCI), 3.8% for late ST (LST ...
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    7. OCT Angiography Findings in Acute Central Serous Chorioretinopathy

      OCT Angiography Findings in Acute Central Serous Chorioretinopathy
      BACKGROUND AND OBJECTIVE: To describe optical coherence tomography angiography (OCTA) findings in patients with acute central serous chorioretinopathy (CSC) compared to conventional imaging methods. PATIENTS AND METHODS: A consecutive series of 11 eyes from 10 healthy patients with acute CSC were included and underwent fluorescein angiography (FA), indocyanine green angiography (ICGA), OCT, fundus autofluorescence (FAF), and OCTA. Obtained OCTA images were evaluated for the presence of serous detachments of the ...
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    8. Catheter-based intraluminal optical coherence tomography of the normal human upper urinary tract in vivo: proof of concept and comparison with an ex-vivo porcine model

      Catheter-based intraluminal optical coherence tomography of the normal human upper urinary tract in vivo: proof of concept and comparison with an ex-vivo porcine model
      Objective : Single-slice, cross-sectional, intraluminal optical-coherence-tomography (OCT) is a new destruction-free optical imaging method that could be applied clinically to examine the upper urinary tract from within. In-vivo access to the human upper urinary tract (UUT) was attempted. Similar performance statistics as in ex-vivo porcine UUT were expected for delineation of different wall layers by in-vivo OCT of human UUTs. MATERIALS AND METHODS : Institutional ethics committee approved OCT in a volunteer ...
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    9. Molecular multimodality imaging: has a long-standing dream come true?

      Molecular multimodality imaging: has a long-standing dream come true?
      Intravascular imaging has incrementally gained in clinical relevance in recent years. First triggered by the introduction of intravascular ultrasound 25 years ago, 1 interest has recently been augmented by the widespread implementation of optical coherence tomography (OCT) in cardiac catheterization laboratories. OCT, because of its outstanding spatial resolution in the range of 1020 m relative to comparative invasive and non-invasive imaging modalities, has been charged with great expectations regarding its ...
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    10. Temporal Trends in Strut-Level Optical Coherence Tomography Evaluation of Coronary Stent Coverage

      Temporal Trends in Strut-Level Optical Coherence Tomography Evaluation of Coronary Stent Coverage
      Objectives We sought to pool data from all studies with reported strut-level data in human subjects evaluated by optical coherence tomography (OCT) surveillance and to compare the aggregate data of stent strut coverage on a longitudinal temporal timeline from initial implantation for different coronary stent subtypes. Background Delayed strut coverage following drug-eluting stent (DES) implantation is an important contributor to late stent thrombosis (LST). OCT can detect stent strut coverage ...
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    11. Introducing Augmented Reality to Optical Coherence Tomography in Ophthalmic Microsurgery

      Introducing Augmented Reality to Optical Coherence Tomography in Ophthalmic Microsurgery
      Augmented Reality (AR) in microscopic surgery has been subject of several studies in the past two decades. Nevertheless, AR has not found its way into everyday microsurgical workflows. The introduction of new surgical microscopes equipped with Optical Coherence Tomography (OCT) enables the surgeons to perform multimodal (optical and OCT) imaging in the operating room. Taking full advantage of such elaborate source of information requires sophisticated intraoperative image fusion, information extraction ...
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    12. Optical coherence tomography indicates disease activity prior to clinical onset of central nervous system demyelination

      Optical coherence tomography indicates disease activity prior to clinical onset of central nervous system demyelination
      Background: Establishing biomarkers for predicting disease activity in demyelinating disease of the central nervous system is crucial for designing appropriate disease modifiying treatment strategies. Objective: To investigate retinal findings and disease activity in patients with radiologically isolated and clinically isolated syndromes. Methods: We performed retinal optical coherence tomography and cerebral magnetic resonance imaging in healthy control individuals ( n =19), in individuals with non-specific white matter lesions ( n =18), and in ...
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    13. Multiple Simultaneous Plaque Erosion in 3 Coronary Arteries

      Multiple Simultaneous Plaque Erosion in 3 Coronary Arteries
      We performed optical coherence tomography (OCT) imaging with matched histology in a 34-year-old man with history of smoking and untreated hyperlipidemia who had suffered from epigastric pain and was found dead at home. Multiple plaque erosions in 3 major coronary arteries were discovered (Figure 1 )
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    14. International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014

      International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014
      ...ini, Tufts University Heidrun Wabnitz, Physikalisch-Technische Bundesanstalt, Germany Vassilis Ntziachristos, Technische Universität München, Germany Maritoni Litorja, NIST Gadi Wollstein, University of Pittsburgh School...
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  2. About Technical University of Munich

    Technical University of Munich

    Technische Universität München ( TUM ; University of Technology, Munich ; Technical University of Munich ) is a research university with campuses in Munich , Garching and Freising - Weihenstephan . It is a member of TU9 , an incorporated society of the largest and most notable German institutes of technology.