1. Technical University of Denmark (DTU)

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    1. Mentioned In 106 Articles

    2. High-resolution mid-infrared optical coherence tomography with kHz line rate

      High-resolution mid-infrared optical coherence tomography with kHz line rate
      We report on mid-infrared optical coherence tomography (OCT) at 4 m based on collinear sum-frequency upconversion and promote the A-scan scan rate to 3 kHz. We demonstrate the increased imaging speed for two spectral realizations, one providing an axial resolution of 8.6 m, and one providing a record axial resolution of 5.8 m. Image performance is evaluated by sub-surface micro-mapping of a plastic glove and real-time monitoring of ...
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    3. New imaging system to detect bowel cancer at the earliest stages using photonics

      New imaging system to detect bowel cancer at the earliest stages using photonics
      Early intervention could prevent many of the 160,000 deaths from colon cancer in Europe each year. Colonoscopies, the gold standard for spotting bowel cancer early, can still miss up to 20% of precancerous cells. But now, thanks to a pan-European health consortium, a new concept that uses photonics to help doctors spot bowel cancer could soon prevent up to half of these deaths and save 9 billion in reduced ...
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    4. Non-Destructive Subsurface Inspection of Marine and Protective Coatings Using Near- and Mid-Infrared Optical Coherence Tomography

      Non-Destructive Subsurface Inspection of Marine and Protective Coatings Using Near- and Mid-Infrared Optical Coherence Tomography
      Near- and mid-infrared optical coherence tomography (OCT) is evaluated as a non-destructive and non-contact reflection imaging modality for inspection of industrial and marine coatings. Near-infrared OCT was used to obtain high-resolution images (~6/2 m lateral/axial) of hidden subsurface cracks and defects in a resin base coating, which had been exposed to high pressure and high temperature to study coating degradation in hostile environments. Mid-infrared OCT was employed for ...
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    5. Delineating papillary dermis around basal cell carcinomas by high and ultrahigh resolution optical coherence tomography

      Delineating papillary dermis around basal cell carcinomas by high and ultrahigh resolution optical coherence tomography
      Bedside diagnosis of skin cancer remains a challenging task. The real-time non-invasive technology of optical coherence tomography (OCT) masters a high diagnostic accuracy in basal cell carcinoma (BCC) but a lower specificity in recognizing imitators and other carcinomas. We investigate the delicate signal of papillary dermis using an in-house developed ultrahigh resolution OCT (UHR-OCT) system with shadow compensation and a commercial multi-focus high resolution OCT (HR-OCT) system for clinical BCC ...
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    6. Shot-noise limited, supercontinuum-based optical coherence tomography

      Shot-noise limited, supercontinuum-based optical coherence tomography
      We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with an axial resolution of 5.9 m at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-to-pulse relative intensity noise of the supercontinuum source. To overcome this disadvantage, we have developed a low-noise supercontinuum source based on an all-normal dispersion ...
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    7. High-speed Time-stretch Optical Coherence Tomography (Thesis)

      High-speed Time-stretch Optical Coherence Tomography (Thesis)
      Supercontinuum sources have great potential in optical coherence tomography due to their ultrabroad spectra, which provide ultrahigh resolution images. High intensity noise of conventional supercontinuum sources, however, has been the limiting factor of widespread adoption, but the emergence of low noise supercontinuum sources promise to change this. In this thesis, both types of supercontinuum sources are tested in a spectrometer-based optical coherence tomography setup, where it is found that the ...
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    8. Postdoc Opening at The Department of Health Technology at the Technical University of Denmark (DTU)

      Postdoc Opening at The Department of Health Technology at the Technical University of Denmark (DTU)
      The Postdoc will join the Biophotonic Imaging group at the Department of Health Technology (DTU Health Tech) consisting of ca 10 employees, including several PhD students and postdocs. Within the group, we are working on the advancement of optical imaging technologies for clinical and biological applications. Currently we have research projects on multimodal imaging combining optical coherence tomography, two-photon excitation fluorescence microscopy, lightsheet microscopy, fibre delivery of ultrashort pulses, as ...
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    9. Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography

      Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography
      Optical coherence tomography angiography (OCTA) is a rapidly developing technique which generates angiographic images non-invasively. This study proposes a method to determine the vessel density in OCTA scans in general and especially the local peripapillary vessel density. The method produces vessel density heatmaps that contain information about the local vessel density. We apply the method in a small study to demonstrate its applicability and its potential to investigate the influence ...
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    10. Chalcogenide-glass polarization-maintaining photonic crystal fiber for mid-infrared supercontinuum generation

      Chalcogenide-glass polarization-maintaining photonic crystal fiber for mid-infrared supercontinuum generation
      In this paper, we report the design and fabrication of a highly birefringent polarization-maintaining photonic crystal fiber (PM-PCF) made from chalcogenide glass, and its application to linearly-polarized supercontinuum (SC) generation in the mid-infrared region. The fiber was drawn using the casting method from As38Se62 glass which features a transmission window from 2 to 10 m and a high nonlinear index of 1.1310-17 m2 /W. It has a zero-dispersion wavelength ...
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    11. Feature Of The Week 04/28/2019: Real-Time High-Resolution Mid-Infrared OCT

      Feature Of The Week 04/28/2019: Real-Time High-ResolutionMid-Infrared OCT
      The potential for improving the penetration depth of optical coherence tomography systems by using light sources with longer wavelengths has been known since the inception of the technique in the early 1990s. Nevertheless, the development of mid-infrared optical coherence tomography has long been challenged by the maturity and fidelity of optical components in this spectral region, resulting in slow acquisition, low sensitivity, and poor axial resolution. In this work, a ...
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    12. Supercontinuum noise reduction by fiber undertapering

      Supercontinuum noise reduction by fiber undertapering
      We demonstrate that the Relative Intensity Noise (RIN) of a supercontinuum source can be significantly reduced using the new concept of undertapering, where the fiber is tapered to a diameter that is smaller than the diameter that gives the shortest blue edge, which is typically regarded as the optimum. We show that undertapering allows to control the second zero dispersion wavelength and use it as a soliton barrier to stop ...
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  2. About Technical University of Denmark (DTU)

    Technical University of Denmark (DTU)

    Technical University of Denmark (DTU) was founded in 1829.  The university was merged with the following Danish research centers: Forskningscenter Risø, Danmarks Fødevareforskning, Danmarks Fiskeriundersøgelser; National Institute for Aquatic Resources; Danmarks Rumcenter, and Danmarks Transport-Forskning. DTU Fotonik, Department of Photonics Engineering is a department at the Technical University of Denmark.