1. Sun Yat-Sen University

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    1. Mentioned In 116 Articles

    2. Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT

      Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT
      The potential of OCT applied for early breast cancer detection attracted significant efforts. The permeability coefficients and the percentages of OCT signal enhancement for normal and cancerous breast tissues have been investigated from the experiments of 20% glucose, 40% glucose, and 20% mannitol in vitro. Obtained results indicate that the permeability coefficient in breast cancer tissue is prominently larger than that in normal breast tissue, while the optical clearing effect ...
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    3. Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography
      ... Ophthalmic Center, 54 S. Xianlie Road, Guangzhou, 510060, China 1. ↵* State Key Laboratory of Ophthalmology, Sun Yat-sen University, Zhongshan Ophthalmic Center, 54 S. Xianlie Road, Guangzhou, 510060, China zhangxl2{at}...
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    4. Noninvasive blood glucose monitoring during oral intake of different sugars with optical coherence tomography in human subjects

      Noninvasive blood glucose monitoring during oral intake of different sugars with optical coherence tomography in human subjects
      The potential of OCT applied to noninvasive blood glucose monitoring has attracted significant efforts. In this work we investigated the feasibility of OCT in monitoring blood glucose during oral intake of different sugars in humans. Five groups of experiments were performed, in which different sugars were used. The OCT signal slope (OCTSS) changed with variation of blood glucose concentration (BGC). A good correlation between OCTSS and BGC was observed in ...
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    5. Assessment of the effects of ultrasound-mediated glucose on permeability of normal, benign, and cancerous human lung tissues with the Fourier-domain optical coherence tomography

      Assessment of the effects of ultrasound-mediated glucose on permeability of normal, benign, and cancerous human lung tissues with the Fourier-domain optical coherence tomography
      The objective of this study was to evaluate the effects of ultrasound-mediated analyte diffusion on permeability of normal, benign, and cancerous human lung tissue in vitro and to find more effective sonophoretic (SP) delivery in combination with the optical clearing agents (OCAs) method to distinguish normal and diseased lung tissues. The permeability coefficients of SP in combination with OCAs diffusion in lung tissue were measured with Fourier-domain optical coherence tomography ...
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    6. Quantitative measurement on optical attenuation coefficient of cell lines 5-8F and 6-10B using optical coherence tomography

      Quantitative measurement on optical attenuation coefficient of cell lines 5-8F and 6-10B using optical coherence tomography
      Oncogenesis and metastasis of tumor are difficult to detect during the clinic therapy. To explore the optical properties of tumorigenesis and metastasis in nasopharyngeal carcinoma (NPC), we assessed the NPC cell lines 5-8F and 6-10B by optical coherence tomography (OCT): first, the OCT images of the two different types of cell pellets were captured. Second, by fitting Beers law to the averaged A-scans in these OCT datasets, the attenuation coefficients ...
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    7. Classification Algorithms Based on Anterior Segment Optical Coherence Tomography Measurements for Detection of Angle Closure

      Classification Algorithms Based on Anterior Segment Optical Coherence Tomography Measurements for Detection of Angle Closure
      ... , * Mingguang He, MD, PhD Affiliations + State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China , * Li-Lian Foo, BEng(Hons) Affiliations + Duke-NUS Graduate Medical ...
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    8. Synergistic effect of hyperosmotic agents and sonophoresis on breast tissue optical properties and permeability studied with spectral domain optical coherence tomography

      Synergistic effect of hyperosmotic agents and sonophoresis on breast tissue optical properties and permeability studied with spectral domain optical coherence tomography
      Hyperosmotic agents have shown great potential in tissue optical clearing. However, the low efficiency of the permeation in biological tissues seriously restricts its application in reality. The synergy of sonophoresis as a penetration enhancer and hyperosmotic agents, 20% glucose (G) and 20% mannitol (M), in optical clearing has been investigated by analyzing the variation of the attenuation coefficients and the permeability coefficients. In the sonophoresis experiments, ultrasound (US) was applied ...
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    9. Characteristics of the macula in amblyopic eyes by optical coherence tomography

      Characteristics of the macula in amblyopic eyes by optical coherence tomography
      AIM: To test the hypothesis that amblyopic neuroretina may have an altered thickness when compared to the normal. METHODS: Twenty-five amblyopic, young patients between the ages of 7 and 11 years old were studied. The interested neuroretina areas are defined into 10 sub-regions according to superior-inferior, nasal-temoral, and peri-para axis, which cross the fovela structure. The thicknesses of ten, defined macular regions were separately measured by optical coherence tomography (OCT ...
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    10. Comparison of anterior ocular biometry between optical low-coherence reflectometry and anterior segment optical coherence tomography in an adult Chinese population

      Comparison of anterior ocular biometry between optical low-coherence reflectometry and anterior segment optical coherence tomography in an adult Chinese population
      ...hou 510060, China. email address From the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China Received 30 October 2011; received in revised form 23 November 2011...
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    11. Quantitative measurement of optical parameters of cell lines 5-8F and 6-10B using polarization sensitive optical coherence tomography

      Quantitative measurement of optical parameters of cell lines 5-8F and 6-10B using polarization sensitive optical coherence tomography
      ...uth China Normal University, Guangzhou 510006, China * ^b Department of Radiation Oncology, Cancer Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China * ^c Laboratory of Optical Imaging and S...
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    12. Quantitative discrimination of NPC cell lines using optical coherence tomography

      Quantitative discrimination of NPC cell lines using optical coherence tomography
      We tried to explore the intrinsic differences in the optical properties of the four representative NPC cell lines on the models of radiobiology and metastasis by OCT. The scattering coefficients and anisotropies were extracted by fitting the average a-scan attenuation curves based on the multiple scatter effect. The values of scattering coefficients and anisotropy factors were 5.21 ± 0.11, 5.30 ± 0.09, 5.92 ± 0.21, 6.97 ...
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    13. 76-90 of 116 « 1 2 3 4 5 6 7 8 »
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  2. About Sun Yat-Sen University

    Sun Yat-Sen University

    Sun Yat-Sen University is located in Guangdong Province, the frontal of reform and opening. At present the University has 4 campuses with a total area of 6.17 square kilometers sitting respectively on both sides of the Pearl River or facing the South China Sea.  Zhongshan Ophthalmic Center is at the Sun Yat-Sen University of Medical Sciences, Guangzhou, China