1. Sun Yat-Sen University

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    1. Mentioned In 200 Articles

    2. Macrophage-like Cells Characterized by En Face Optical Coherence Tomography was Associated with Fluorescein Vascular Leakage in Behçet's Uveitis

      Macrophage-like Cells Characterized by En Face Optical Coherence Tomography was Associated with Fluorescein Vascular Leakage in Behçet's Uveitis
      Purpose: To investigate the features of macrophage-like cell (MLC) characterized by en face optical coherence tomography (OCT) in Behet's uveitis (BU). Methods: The extent of fluorescein vascular leakage (FVL) was graded on a scale of 0-3 (0=none, 1=mild, 2=moderate, 3=severe) for the optic nerve head (ONH), macula and peripheral retina. The 3m en face OCT slabs on inner limiting membrane of ONH or macular region ...
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    3. Prediction of the Short-Term Therapeutic Effect of Anti-VEGF Therapy for Diabetic Macular Edema Using a Generative Adversarial Network with OCT Images

      Prediction of the Short-Term Therapeutic Effect of Anti-VEGF Therapy for Diabetic Macular Edema Using a Generative Adversarial Network with OCT Images
      Purpose: To generate and evaluate individualized post-therapeutic optical coherence tomography (OCT) images that could predict the short-term response of anti-vascular endothelial growth factor (VEGF) therapy for diabetic macular edema (DME) based on pre-therapeutic images using generative adversarial network (GAN). Methods: Real-world imaging data were collected at the Department of Ophthalmology, Qilu Hospital. A total of 561 pairs of pre-therapeutic and post-therapeutic OCT images of patients with DME were retrospectively included ...
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    4. Choriocapillaris flow deficit and the risk of referable diabetic retinopathy: a longitudinal SS-OCTA study

      Choriocapillaris flow deficit and the risk of referable diabetic retinopathy: a longitudinal SS-OCTA study
      Aims To investigate the association between the choriocapillaris flow deficit percentage (CC FD%) and the 1-year incidence of referable diabetic retinopathy (RDR) in participants with type 2 diabetes mellitus (DM). Methods This prospective cohort study included participants with type 2DM. The DR status was graded based on the ETDRS-7 photography. The CC FD% in the central 1mm area, inner circle (1.5mm to 2.5mm), outer circle (2.5mm to ...
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    5. Ocular Factors of Fractal Dimension and Blood Vessel Tortuosity Derived From OCTA in a Healthy Chinese Population

      Ocular Factors of Fractal Dimension and Blood Vessel Tortuosity Derived From OCTA in a Healthy Chinese Population
      Purpose: To identify the ocular factors of microvascular fractal dimension (FD) and blood vessel tortuosity (BVT) of macula measured with optical coherence tomography angiography (OCTA) in a healthy Chinese population. Methods: Healthy subjects without ocular disorders were recruited at Zhongshan Ophthalmic Center. The FD and BVT in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) at the macula were obtained from OCTA images. The FD was calculated using ...
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    6. Mixed pyramid attention network for nuclear cataract classification based on anterior segment OCT images

      Mixed pyramid attention network for nuclear cataract classification based on anterior segment OCT images
      Nuclear cataract (NC) is a leading ocular disease globally for blindness and vision impairment. NC patients can improve their vision through cataract surgery or slow the opacity development with early intervention. Anterior segment optical coherence tomography (AS-OCT) image is an emerging ophthalmic image type, which can clearly observe the whole lens structure. Recently, clinicians have been increasingly studying the correlation between NC severity levels and clinical features from the nucleus ...
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    7. CHANGES IN MYOPIC MACULOPATHY BASED ON ATN CLASSIFICATION SYSTEM: An Optical Coherence Tomography Angiography Study

      CHANGES IN MYOPIC MACULOPATHY BASED ON ATN CLASSIFICATION SYSTEM: An Optical Coherence Tomography Angiography Study
      Purpose: To assess changes in myopic maculopathy based on the ATN classification system with optical coherence tomography angiography . Methods: This was a cross-sectional study. The macular choroidal thickness (MCT) and the choriocapillaris flow (CC) were measured with optical coherence tomography angiography . The relationship of MCT and CC with different chorioretinal atrophy (A), myopic foveoschisis (T), and myopic neovascularization (N) grades was investigated. Results: One hundred and fifty-three participates (219 eyes ...
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    8. Today’s Mistakes and Tomorrow’s Wisdom in Endoscopic Imaging of Barrett’s Esophagus

      Today’s Mistakes and Tomorrow’s Wisdom in Endoscopic Imaging of Barrett’s Esophagus
      Background:Esophageal adenocarcinoma (EAC) is one of the main causes of cancer-related deaths worldwide and its incidence is rising. Barretts esophagus (BE) can develop low- and high-grade dysplasia which can progress to EAC overtime. The golden standard to detect dysplastic BE (DBE) or EAC is surveillance with high-definition white-light endoscopy (HD-WLE) and random biopsies according to the Seattle protocol. However, this method is time-consuming and associated with a remarkable miss ...
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    9. Characteristic Assessment of Angiographies at Different Depths with AS-OCTA: Implication for Functions of Post-Trabeculectomy Filtering Bleb

      Characteristic Assessment of Angiographies at Different Depths with AS-OCTA: Implication for Functions of Post-Trabeculectomy Filtering Bleb
      This study aimed to analyze the quantitative vascular biomarkers of filtering bleb function at different depths using anterior segment optical coherence tomography angiography (AS-OCTA). This cross-sectional study is registered on Clinicaltrails.gov ( NCT04515017 ). Forty-six eyes with primary open-angle glaucoma that had undergone trabeculectomy with mitomycin-C for more than six months were included. Vessel density (VD) and vessel diameter index (VDI) in the superficial layer (SL), Tenon's layer (TL), and ...
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    10. Predicting Optical Coherence Tomography-Derived High Myopia Grades From Fundus Photographs Using Deep Learning

      Predicting Optical Coherence Tomography-Derived High Myopia Grades From Fundus Photographs Using Deep Learning
      Purpose: To develop an artificial intelligence (AI) system that can predict optical coherence tomography (OCT)-derived high myopia grades based on fundus photographs. Methods: In this retrospective study, 1,853 qualified fundus photographs obtained from the Zhongshan Ophthalmic Center (ZOC) were selected to develop an AI system. Three retinal specialists assessed corresponding OCT images to label the fundus photographs. We developed a novel deep learning model to detect and predict ...
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    11. Characterization of Macrophage-Like Cells in Retinal Vein Occlusion Using En Face Optical Coherence Tomography

      Characterization of Macrophage-Like Cells in Retinal Vein Occlusion Using En Face Optical Coherence Tomography
      Purpose: To investigate the clinical features of a macrophage-like cell (MLC) obtained by en face optical coherence tomography (OCT) in retinal vein occlusion (RVO). Methods: The study involved 36 patients with treatment-nave unilateral acute RVO, including 21 branch RVO (BRVO) and 15 central RVO. Vessel density and macular thickness were quantified using OCT angiography. A 3-m en face OCT slab on the inner limiting membrane in the optic nerve head ...
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    12. Radiation optic neuropathy diagnosis in nasopharyngeal carcinoma patients with radiation encephalopathy

      Radiation optic neuropathy diagnosis in nasopharyngeal carcinoma patients with radiation encephalopathy
      Aim To develop a suitable radiation optic neuropathy (RON) diagnostic model based on optical coherence tomography angiography (OCTA) and to reveal the correlation between endocrine and OCTA indexes in nasopharyngeal carcinoma (NPC) patients with radiation encephalopathy (RE). Methods This retrospective cross-sectional study included seventy-seven male NPC patients with RE following radiotherapy (41 non-RON and 36 RON). Endocrine and OCTA indexes were collected. The macular and peripapillary vessel density (VD) were ...
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    13. Optical phase modulation by natural eye movements: application to time-domain FF-OCT image retrieval

      Optical phase modulation by natural eye movements: application to time-domain FF-OCT image retrieval
      Eye movements are commonly seen as an obstacle to high-resolution ophthalmic imaging. In this context we study the natural axial movements of the in vivo human eye and show that they can be used to modulate the optical phase and retrieve tomographic images via time-domain full-field optical coherence tomography (TD-FF-OCT). This approach opens a path to a simplified ophthalmic TD-FF-OCT device, operating without the usual piezo motor-camera synchronization. The device ...
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    14. Adaptive feature squeeze network for nuclear cataract classification in AS-OCT image

      Adaptive feature squeeze network for nuclear cataract classification in AS-OCT image
      Nuclear cataract (NC) is an age-related cataract disease. Cataract surgery is an effective method to improve the vision and life quality of NC patients. Anterior segment optical coherence tomography (AS-OCT) images are noninvasive, reproductive, and easy-measured, which can capture opacity clearly on the lens nucleus region. However, automatic AS-OCT-based NC classification research has not been extensively studied. This paper proposes a novel convolutional neural network (CNN) framework named Adaptive Feature ...
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    15. Evaluation of Wide Corneal Epithelial Remodeling after Small Incision Lenticule Extraction (SMILE) with Wide-Field Optical Coherence Tomography

      Evaluation of Wide Corneal Epithelial Remodeling after Small Incision Lenticule Extraction (SMILE) with Wide-Field Optical Coherence Tomography
      ...n reasonable request. This study was approved by the Medical Ethics Committee of Zhongshan Ophthalmic Center, Sun Yat-sen University (2017KYPJ087). Written informed consent was obtained from each patient before the study...
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    16. 1-15 of 200 1 2 3 4 ... 12 13 14 »
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  2. About Sun Yat-Sen University

    Sun Yat-Sen University

    Sun Yat-Sen University is located in Guangdong Province, the frontal of reform and opening. At present the University has 4 campuses with a total area of 6.17 square kilometers sitting respectively on both sides of the Pearl River or facing the South China Sea.  Zhongshan Ophthalmic Center is at the Sun Yat-Sen University of Medical Sciences, Guangzhou, China