1. Sun Yat-Sen University

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    1. Mentioned In 130 Articles

    2. Quantitative Evaluation of Parafoveal Microvasculature Changes in Eyes with Exudative Circumscribed Choroidal Haemangioma : An Optical Coherence Tomography Angiography Study

      Quantitative Evaluation of Parafoveal Microvasculature Changes in Eyes with Exudative Circumscribed Choroidal Haemangioma : An Optical Coherence Tomography Angiography Study
      Background : To quantitative evaluation of parafoveal microvasculature changes in eyes with exudative circumscribed choroidal haemangioma (CCH) compared with age- and gender-controlled healthy eyes. Methods : This was a cross-sectional, case-control study. 82 eyes of eighty-two subjects including 41 eyes of forty-one subjects in the exudative CCH group and 41 eyes of forty-one subjects in the age- and gender-controlled healthy eye group were enrolled in this study. Optical coherence tomography angiography (OCTA ...
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    3. OCT-Angiography comparison between obstructive sleep apnea children and normal subjects in China

      OCT-Angiography comparison between obstructive sleep apnea children and normal subjects in China
      Purpose Using optical coherence tomography angiography (OCT-A) to compare the retinal micro vessel alteration between obstructive sleep apnea (OSA) children and normal subjects. Methods One hundred-thirty-two eyes (132 participants) were recruited in this study. The average age of OSA group (66 eyes) and healthy control group (66 eyes) were 6.23 1.73 and 6.76 1.89 years, respectively). The retinal vascular network density indices and the fovea avascular ...
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    4. Macular vessel density in diabetes and diabetic retinopathy with swept-source optical coherence tomography angiography

      Macular vessel density in diabetes and diabetic retinopathy with swept-source optical coherence tomography angiography
      Purpose Previous studies on the association between macular vessel density (VD) and diabetic retinopathy had conflicting conclusions. This study assessed the alterations of macular VD, as well as other factors, in diabetic patients using swept-source optical coherence tomography angiography (SS-OCTA) in a large-scale sample from Chinese communities. Methods Patients with type 2 diabetes without history of ocular treatment were recruited from 2017 to 2018. The average and quadrant parafoveal vessel ...
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    5. Quantitative Evaluation of Parafoveal Microvasculature Changes in Eyes With Exudative Circumscribed Choroidal Haemangioma: An Optical Coherence Tomography Angiography Study

      Quantitative Evaluation of Parafoveal Microvasculature Changes in Eyes With Exudative Circumscribed Choroidal Haemangioma: An Optical Coherence Tomography Angiography Study
      Circumscribed choroidal haemangioma (CCH) is an uncommon, potentially congenital benign vascular hamartomas which typically manifests as an elevated mass with reddish-orange pigmentation located posteriorly to the equator, mostly in the macular and peripapillary region. Despite its benign nature, cystoid macular edema (CME) or SRF due to the exudations from the exudative CCH can cause visual impairment. Diagnosis is often suspected clinically, and multimodal imaging is useful for the differential diagnosis ...
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    6. Comparison of a New Swept-Source Anterior Segment Optical Coherence Tomography and a Scheimpflug Camera for Measurement of Corneal Curvature

      Comparison of a New Swept-Source Anterior Segment Optical Coherence Tomography and a Scheimpflug Camera for Measurement of Corneal Curvature
      Purpose: To evaluate the agreement of corneal curvature measured by a newly introduced swept-source anterior segment optical coherence tomography (CASIA2) and Pentacam (Oculus, Wetzlar, Germany). Methods: Corneal curvature was measured in 49 healthy subjects (age: 24.8 4.36) by using CASIA2 and Pentacam . Repeatability was evaluated for CASIA2, and agreement between the CASIA2 and Pentacam was assessed. The coefficient of repeatability, the relative coefficient of repeatability, the range of ...
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    7. AGE Challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomography

      AGE Challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomography
      Angle closure glaucoma (ACG) is a more aggressive disease than open-angle glaucoma, where the abnormal anatomical structures of the anterior chamber angle (ACA) may cause an elevated intraocular pressure and gradually leads to glaucomatous optic neuropathy and eventually to visual impairment and blindness. Anterior Segment Optical Coherence Tomography (AS-OCT) imaging provides a fast and contactless way to discriminate angle closure from open angle. Although many medical image analysis algorithms have ...
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    8. Relationship Between Renal Function and Choroidal Thickness in Type 2 Diabetic Patients Detected by Swept-Source Optical Coherence Tomography

      Relationship Between Renal Function and Choroidal Thickness in Type 2 Diabetic Patients Detected by Swept-Source Optical Coherence Tomography
      Purpose : To investigate the relationship between renal function and choroidal thickness (CT) in ocular treatment-nave patients with diabetes mellitus using swept-source optical coherence tomography (SS-OCT). Methods : This cross-sectional study recruited type 2 diabetes mellitus (T2DM) patients with no history of ocular treatment from communities in Guangzhou, China. The estimated glomerular filtration rates (eGFR) were calculated by using the Xiangya formula. The impaired renal function was defined as eGFR 60 mL ...
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    9. Comparison of radius of anterior lens surface curvature measurements in vivo using the anterior segment optical coherence tomography and Scheimpflug imaging

      Comparison of radius of anterior lens surface curvature measurements in vivo using the anterior segment optical coherence tomography and Scheimpflug imaging
      Background: To assess the radius of anterior lens surface curvature (RAL) measurements with anterior segment optical coherence tomography (AS-OCT) in comparison with Scheimpflug imaging. Methods: This prospective, cross-sectional study was carried out at Zhongshan Ophthalmic Center, Guangzhou, China. We enrolled 59 eyes, including 30 eyes from 30 cataractous volunteers (59 to 87 years) and 29 eyes from 29 young participants (19 to 49 years). After mydriasis, the RAL was measured ...
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    10. Features of the Choroidal Structures in Myopic Children Based on Image Binarization of Optical Coherence Tomography

      Features of the Choroidal Structures in Myopic Children Based on Image Binarization of Optical Coherence Tomography
      Purpose : To evaluate the features of the choroidal structures in the eyes of myopic children obtained by enhanced depth imaging optical coherence tomography (EDI-OCT). Methods : Ninety-six myopic children with low to moderate myopia (spherical equivalent refractive error [SER], 5.75 to 1.00 diopter) were included in this cross-sectional study. Ocular biometrics were measured using an optical low-coherence reflectometry device. Data of the choroidal structures extracted from a 7500-m cross-sectional ...
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    11. Multi-modal Anterior Eye Imager Combining Ultra-High Resolution OCT and Microvascular Imaging for Structural and Functional Evaluation of the Human Eye

      Multi-modal Anterior Eye Imager Combining Ultra-High Resolution OCT and Microvascular Imaging for Structural and Functional Evaluation of the Human Eye
      To establish complementary information for the diagnosis and evaluation of ocular surface diseases, we developed a multi-modal, non-invasive optical imaging platform by combining ultra-high resolution optical coherence tomography (UHR-OCT) with a microvascular imaging system based on slit-lamp biomicroscopy. Our customized UHR-OCT module achieves an axial resolution of 2.9 m in corneal tissue with a broadband light source and an A-line acquisition rate of 24 kHz with a line array ...
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    12. MDAN-UNet: Multi-Scale and Dual Attention Enhanced Nested U-Net Architecture for Segmentation of Optical Coherence Tomography Images

      MDAN-UNet: Multi-Scale and Dual Attention Enhanced Nested U-Net Architecture for Segmentation of Optical Coherence Tomography Images
      Optical coherence tomography (OCT) is an optical high-resolution imaging technique for ophthalmic diagnosis. In this paper, we take advantages of multi-scale input, multi-scale side output and dual attention mechanism and present an enhanced nested U-Net architecture (MDAN-UNet), a new powerful fully convolutional network for automatic end-to-end segmentation of OCT images. We have evaluated two versions of MDAN-UNet (MDAN-UNet-16 and MDAN-UNet-32) on two publicly available benchmark datasets which are the Duke ...
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    13. Association of renal function with retinal vessel density in patients with type 2 diabetes by using swept-source optical coherence tomographic angiography

      Association of renal function with retinal vessel density in patients with type 2 diabetes by using swept-source optical coherence tomographic angiography
      Aims To investigate the relationship between retinal vessel density and renal function in patients with diabetes mellitus (DM) using non-invasive optical coherence tomographic angiography (OCTA). Methods This prospective cross-sectional study recruited ocular-treatment-nave patients with DM registered in the community of Guangzhou, China. The retinal vessel density of the superficial capillary plexus in the macula was obtained by using swept-source OCTA imaging. The Xiangya equation was used to calculate the estimated ...
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    14. Macular vessel density in diabetes and diabetic retinopathy with swept-source optical coherence tomography angiography

      Macular vessel density in diabetes and diabetic retinopathy with swept-source optical coherence tomography angiography
      Purpose: Previous studies on the association between macular vessel density (VD) and diabetic retinopathy had conflicting conclusions. This study assessed the alterations of macular VD, as well as other factors, in diabetic patients using swept-source optical coherence tomography angiography (SS-OCTA) in a large-scale sample from Chinese communities. Methods: Patients with type 2 diabetes without history of ocular treatment were recruited from 2017 to 2018. The average and quadrant parafoveal vessel ...
      Read Full Article
    15. Automatic Segmentation and Visualization of Choroid in OCT with Knowledge Infused Deep Learning

      Automatic Segmentation and Visualization of Choroid in OCT with Knowledge Infused Deep Learning
      The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo, because it does not suffer from the information contamination of the outer retina in fundus photography and scanning laser ophthalmoscopy and the resolution deficiency in ocular ultrasound. We propose a biomarker infused global-to-local network, for the ...
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  2. About Sun Yat-Sen University

    Sun Yat-Sen University

    Sun Yat-Sen University is located in Guangdong Province, the frontal of reform and opening. At present the University has 4 campuses with a total area of 6.17 square kilometers sitting respectively on both sides of the Pearl River or facing the South China Sea.  Zhongshan Ophthalmic Center is at the Sun Yat-Sen University of Medical Sciences, Guangzhou, China