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2. Comparison of vascular parameters between normal cynomolgus macaques and healthy humans by optical coherence tomography angiography
  
  Explore BMC Ophthalmology Oct 15 2019 Ophthalmology
  
  Background The metabolic activity of retina is higher than other human tissues and is crucial to the vision. Cynomolgus macaques is widely used in ophthalmic disease research. The evaluation and comparison of macular and optic disc vascular circulation parameters between normal adult cynomolgus macaques and healthy adult humans using OCT-A can promote better use of nonhuman primate models in studies of ophthalmic vascular disease. Methods Twelve normal adult cynomolgus macaques ...
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  Mentions: Optovue Sun Yat-Sen University
3. Comparison of clinical outcomes of different components of diabetic macular edema on optical coherence tomography
  
  Explore Home - Springer Sep 22 2019 Ophthalmology
  
  To evaluate the edema reduction after intravitreal injection of ranibizumab (IVR) in two diabetic macular edema (DME) components in the same eye using optical coherence tomography (OCT). Methods Totally 113 eyes with mixed OCT pattern of DME were included. All the eyes underwent best-corrected visual acuity (BCVA) examination and OCT scanning at baseline and follow-up visits (1, 3, and 6 months after 3 monthly consecutive IVR). The mixed OCT pattern ...
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4. Comparison between non-visualized polyps and visualized polyps on optical coherence tomography angiography in polypoidal choroidal vasculopathy
  
  Explore Home - Springer Aug 30 2019 Ophthalmology
  
  Purpose To determine the underlying reasons for the non-visualization of polyps on en face optical coherence tomography angiography (OCTA) in patients with polypoidal choroidal vasculopathy (PCV). Methods A cross-sectional study of consecutive treatment-nave 30 eyes with active PCV was included. Results of fundus photography, fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), spectral domain optical coherence tomography (SD-OCT), and en face OCTA were analyzed. Results A total of 64 active ...
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  Mentions: Sun Yat-Sen University
5. Microvascular changes after conbercept therapy in central retinal vein occlusion analyzed by optical coherence tomography angiography
  
  Explore 欢迎访问国际眼科杂志编辑部 May 28 2019 Ophthalmology
  
  AIM : To investigate microvascular changes in eyes with central retinal vein occlusion (CRVO) complicated by macular edema before and after intravitreal conbercept injection and evaluate correlations between these changes and best-corrected visual acuity (BCVA) and retinal thickness. METHODS : Twenty-eight eyes of 28 patients with macular edema caused by CRVO were included in this retrospective study. All patients received a single intravitreal conbercept injection to treat macular edema. BCVA and the ...
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  Mentions: Sun Yat-Sen University
6. Quantitative Analysis of Retinal Microvascular Changes after Conbercept Therapy in Branch Retinal Vein Occlusion Using Optical Coherence Tomography Angiography
  
  Explore Karger Publishers May 28 2019 Ophthalmology
  
  Purpose: To quantitatively evaluate microvascular changes in eyes with macular oedema due to branch retinal vein occlusion (BRVO) using optical coherence tomography angiography (OCTA) before and after intravitreal conbercept injection and the correlation of such changes with best-corrected visual acuity (BCVA) and retinal thickness. Methods: Twenty-eight eyes of 28 patients treated with a single intravitreal injection of conbercept for macular oedema due to BRVO were included in this study. The ...
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7. Automatic detection of retinal regions using fully convolutional networks for diagnosis of abnormal maculae in optical coherence tomography images
  
  Explore SPIE Digital Library May 25 2019 Ophthalmology
  
  In conventional retinal region detection methods for optical coherence tomography (OCT) images, many parameters need to be set manually, which is often detrimental to their generalizability. We present a scheme to detect retinal regions based on fully convolutional networks (FCN) for automatic diagnosis of abnormal maculae in OCT images. The FCN model is trained on 900 labeled age-related macular degeneration (AMD), diabetic macular edema (DME) and normal (NOR) OCT images ...
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  Mentions: Sun Yat-Sen University Tsinghua University
8. Peripapillary and Macular Vessel Density in Dysthyroid Optic Neuropathy: An Optical Coherence Tomography Angiography Study
  
  Explore IOVS Journal May 7 2019 Ophthalmology
  
  Purpose : To evaluate peripapillary and macular vessel density in eyes with dysthyroid optic neuropathy (DON) and its correlation with visual function. Methods : Patients diagnosed as thyroid-associated ophthalmopathy (TAO) with or without DON and healthy participants were recruited. All subjects underwent a complete ophthalmic examination and optical coherence tomography angiography centered on the fovea and the optic nerve head. Microvascular measurements were summarized as vessel density in the whole image and ...
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9. Effects of chronic elevated intraocular pressure on parameters of optical coherence tomography in rhesus monkeys
  
  Explore 欢迎访问国际眼科杂志编辑部 Apr 30 2019 Ophthalmology
  
  AIM : To determine the progression of parameters from optical coherence tomography (OCT) in chronic elevated intraocular pressure (IOP) monkeys. METHODS : A chronic elevated IOP model of rhesus monkeys was induced by laser photocoagulation. Representative OCT parameters, including the average and four-quadrant retinal nerve fiber layer (RNFL) thickness, and parameters from optic nerve head (ONH) analysis were collected before and after laser treatments biweekly for up to 28wk. The performance of ...
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10. In vivo detecting mouse persistent hyperplastic primary vitreous by Spectralis Optical Coherence Tomography
  
  Explore ScienceDirect Feb 28 2019 Ophthalmology
  
  To identify imaging characteristics of mouse persistent hyperplastic primary vitreous (PHPV) by Spectralis Optical Coherence Tomography (OCT), as well as to assess and compare the sensitivity and precision of OCT with color photography and Fundus Fluorescein Angiography (FFA) imaging in detecting mouse PHPV. NOTCH4 / C57BL/6J mice (224 eyes) aged from 3 months to 7 months were examined in this study. Color photography (CP), FFA and OCT imaging were utilized ...
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11. Optimized Deep Convolutional Neural Networks for Identification of Macular Diseases from Optical Coherence Tomography Images
  
  Explore MDPI Open Access Journals Platform Feb 26 2019 Ophthalmology
  
  Finetuning pre-trained deep neural networks (DNN) delicately designed for large-scale natural images may not be suitable for medical images due to the intrinsic difference between the datasets. We propose a strategy to modify DNNs, which improves their performance on retinal optical coherence tomography (OCT) images. Deep features of pre-trained DNN are high-level features of natural images. These features harm the training of transfer learning. Our strategy is to remove some ...
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  Mentions: Sun Yat-Sen University Tsinghua University
12. Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT
  
  Explore OSA | OSA Publishing Jan 29 2019 Ophthalmology
  
  We describe recent technological progress in multimodal en face full-field optical coherence tomography that has allowed detection of slow and fast dynamic processes in the eye. We show that by combining static, dynamic and fluorescence contrasts we can achieve label-free high-resolution imaging of the retina and anterior eye with temporal resolution from milliseconds to several hours, allowing us to probe biological activity at subcellular scales inside 3D bulk tissue. Our ...
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  Mentions: University of Pittsburgh Claude Boccara Sun Yat-Sen University
13. Evaluation of spectral domain optical coherence tomography parameters in discriminating preperimetric glaucoma from high myopia
  
  Explore 欢迎访问国际眼科杂志编辑部 Jan 28 2019 Ophthalmology
  
  AIM : To evaluate the diagnostic ability of macular ganglion cell-inner plexiform layer (GCIPL) thickness obtained by spectral-domain optical coherence tomography (SD-OCT) in discriminating non-highly myopic eyes with preperimetric glaucoma (PPG) from highly myopic healthy eyes. METHODS : A total of 254 eyes, including 76 normal controls (NC), 116 eyes with high myopia (HM) and 62 non-highly myopic eyes with PPG were enrolled. The diagnostic ability of OCT parameters was accessed by ...
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14. Do microvascular changes occur preceding neural impairment in early-stage diabetic retinopathy? Evidence based on the optic nerve head using optical coherence tomography angiography
  
  Explore Home - Springer Jan 28 2019 Ophthalmology
  
  Aims To evaluate the microvascular and neural differences of the optic nerve head (ONH) between type 2 diabetes mellitus (T2DM) subjects and controls. Methods This was a cross-sectional observational study. One hundred and eight eyes of 108 T2DM subjects with or without diabetic retinopathy (DR) (54 preclinical DR and 54 mild-to-moderate DR) were included. Fifty-two eyes of 52 healthy subjects were included as controls. The 4.5-mm Angio Disc scan ...
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  Mentions: Sun Yat-Sen University
15. Optical Coherence Tomography Angiography in Familial Exudative Vitreoretinopathy: Clinical Features and Phenotype-Genotype Correlatio
  
  Explore IOVS Journal Dec 8 2018 Ophthalmology
  
  Purpose : To evaluate the microstructure of the fovea in patients with familial exudative vitreoretinopathy (FEVR) compared to healthy controls using optical coherence tomography angiography (OCTA). Methods : In this consecutive, cross-sectional, observational case series, 41 eyes of 41 patients diagnosed as FEVR and 37 eyes in 37 control subjects were studied. OCTA was utilized to automatically measure the foveal avascular zone (FAZ) and the vessel density (VD). Inner retinal thicknesses (IRT ...
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16. Macular microvasculature features before and after vitrectomy in idiopathic macular epiretinal membrane: an OCT angiography analysis
  
  Explore Nature Publishing Group Nov 22 2018 Ophthalmology
  
  Purpose To evaluate pre-operative and post-operative morphologic characteristics in idiopathic macular epiretinal membrane (ERM) by optical coherence tomography angiography (OCTA). Methods Thirty-three subjects with unilateral idiopathic ERM were enrolled and the contralateral eyes served as controls. Vascular parameters including superficial capillary plexus (SCP), deep capillary plexus (DCP), outer capillary plexus (OCP), and choroidal capillary plexus (CCP) were evaluated by OCTA. Results The superficial foveal avascular zone (FAZ) was significantly smaller ...
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  Mentions: Sun Yat-Sen University
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