1. Steven J. Matcher

    0 Comments Leave a Comment

    61-74 of 74 « 1 2 3 4 5
    1. Mentioned In 74 Articles

    2. Using swept-source optical coherence tomography to monitor the formation of neo-epidermis in tissue-engineered skin

      Using swept-source optical coherence tomography to monitor the formation of neo-epidermis in tissue-engineered skin
      There is an increasing need for a robust, simple to use, non-invasive imaging technology to follow tissue-engineered constructs as they develop. Our aim was to evaluate the use of swept-source optical coherence tomography (SS-OCT) to image tissue-engineered skin as it developed over several weeks. Tissue-engineered skin was produced using both de-epithelialized acellular dermis (DED) and amorphous collagen gels. In both cases the epidermis could be readily distinguished from the neodermis ...
      Read Full Article
    3. Doppler optical coherence tomography in cardiovascular applications

      Doppler optical coherence tomography in cardiovascular applications
      Abstract  The study of flow dynamics in complex geometry vessels is highly important in various biomedical applications where the knowledge of the mechanic interactions between the moving fluid and the housing media plays a key role for the determination of the parameters of interest, including the effect of blood flow on the possible rupture of atherosclerotic plaques. Doppler Optical Coherence Tomography (DOCT), as a functional extension of Optical Coherence Tomography ...
      Read Full Article
    4. Application of Doppler Optical Coherence Tomography in rheological studies: Blood flow and vessels mechanical properties evaluation

      Doppler Optical Coherence Tomography (DOCT) is a noninvasive optical diagnostic technique, which is well suited for the quantitative mapping of microflow velocity profiles and the analysis of flow-vessel interactions. The noninvasive imaging and quantitative analysis of blood flow in the complex-structured vascular bed is required in many biomedical applications, including those where the determination of mechanical properties of vessels or the knowledge of the mechanic interactions between the flow and ...
      Read Full Article
    5. Evaluation of a cheap ultrasonic stage for light source coherence function measurement, optical coherence tomography and dynamic focusing

      We evaluate the performance of a cheap ultrasonic stage in setups related to optical coherence tomography. The stage was used in several configurations: (1) optical delay line in an optical coherence tomography (OCT) setup; (2) as a delay line measuring coherence function of a low coherence source (e.g. superluminescent diode) and (3) in a dynamic focusing arrangement. The results are as follows: the stage is suitable for coherence function ...
      Read Full Article
    6. Evaluation of a cheap ultrasonic stage for light source coherence function measurement, optical coherence tomography, optical coherence microscopy, and dynamic focusing

      ... Techniques IV Conference Chairs: Peter E. Andersen, Brett E. Bouma ABSTRACT REFERENCES (43) Nikola Krstajic, Stephen J. Matcher, and David Childs The Univ. of Sheffield (United Kingdom) Wiendelt Steenbergen The Univ. of...
      Read Full Article
    7. Novel optical imaging technique to determine the 3-D orientation of collagen fibers in cartilage: variable-incidence angle polarization-sensitive optical coherence tomography

      Objective To investigate a novel optical method to determine the three dimensional (3-D) structure of articular cartilage collagen non-destructively. Methods Polarization-sensitive optical coherence tomography was used to determine the apparent optical birefringence of articular cartilage for a number of different illumination directions. A quantitative method based on the theory of light propagation in uniaxial crystalline materials was validated on equine flexor tendon. Qualitative maps of fiber polar and azimuthal orientation ...
      Read Full Article
    8. 61-74 of 74 « 1 2 3 4 5
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Steven J. Matcher

    Steven J. Matcher

    Stephen Matcher graduated from Imperial College London with a BSc in Physics and subsequently a PhD in optical astronomy, where he used high-speed, low-light-level imaging to overcome atmospheric turbulence and achieve diffraction-limited ground-based imaging. He translated his expertise in low-light-level imaging into medicine at University College London, where he developed near-infrared spectroscopy techniques to study tissue oxygen delivery, especially in newborn infants at risk from birth asphyxia. He then joined the staff of the Physics department at the University of Exeter, where he established research programmes in visible light spectroscopy of skin and optical coherence tomography (OCT). In 2006 he joined the University of Sheffield where he is currently Reader in Biomedical Engineering. His chief research interest lies in the development and application of novel biophotonic imaging tools to aid the characterisation of native and engineered biological tissues. Primarily he works with OCT, including novel variants such as polarization-sensitive OCT for the non-invasive assessment of collagen organization and Doppler OCT for the measurement of fluid flow. He is currently collaborating with clinical colleagues to improve the detection of corneal stem cells post-implantation, to provide tools for the early detection and staging of epithelial cancer and to develop non-invasive tools to characterise skin barrier function. He also actively collaborates with the National Centre for III-V Technologies to develop improved light sources for biophotonic imaging.


    1. I am very pleased that the RAE is supporting my secondment to Michelson Diagnostics, a world leader in OCT imaging and I hope that my skills and expertise will be of practical benefit to the company
      In Dr Stephen Matcher Biomedical Imaging Expert Seconded to Michelson Diagnostics