1. Steven J. Matcher

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    1. Mentioned In 74 Articles

    2. Feature Of The Week 5/6/12: University of Sheffield investigates models to study the 3D structural orientation of the collagen fibers in articular cartilage using PS-OCT

      Feature Of The Week 5/6/12: University of Sheffield investigates models to study the 3D structural orientation of the collagen fibers in articular cartilage using PS-OCT
      Researchers from the University of Sheffield recently showed the applicability of an extended Jones matrix calculus approach to understand the 3D orientation information of collagen fiber in articular cartilage using multi-angle polarization sensitive optical coherence tomography OCT imaging.  The work could potentially advance the use of OCT imaging in orthopaedics and improve our understanding of the biomechanics and pathological changes occurring in articular cartilage during osteoarthritis.For more information see ...
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    3. Experimental validation of an extended Jones matrix calculus model to study the 3D structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography

      Experimental validation of an extended Jones matrix calculus model to study the 3D structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography
      ...maging ToC Category: Optical Coherence Tomography Citation Deepa K. Kasaragod, Zenghai Lu, James Jacobs, and Stephen J. Matcher, "Experimental validation of an extended Jones matrix calculus model to study the 3D struct...
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    4. Polarization-sensitive optical coherence tomography using continuous polarization modulation with arbitrary phase modulation amplitude

      Polarization-sensitive optical coherence tomography using continuous polarization modulation with arbitrary phase modulation amplitude
      We demonstrate theoretically and experimentally that the phase retardance and relative optic-axis orientation of a sample can be calculated without prior knowledge of the actual value of the phase modulation amplitude when using a polarization-sensitive optical coherence tomography system based on continuous polarization modulation (CPM-PS-OCT). We also demonstrate that the sample Jones matrix can be calculated at any values of the phase modulation amplitude in a reasonable range depending on ...
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    5. Polarization-sensitive optical coherence tomography measurements with different phase modulation amplitude when using continuous polarization modulation

      Polarization-sensitive optical coherence tomography measurements with different phase modulation amplitude when using continuous polarization modulation
      We demonstrate theoretically and experimentally that the phase retardance and relative optic-axis orientation of a sample can be calculated without prior knowledge of the actual value of the phase modulation amplitude when using a polarization-sensitive optical coherence tomography system based on continuous polarization modulation (CPM-PS-OCT). We also demonstrate that the sample Jones matrix can be calculated at any values of the phase modulation amplitude in a reasonable range depending on ...
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    6. Optical coherence tomography based angle-resolved backscattering studies on bovine tendon and cartilage

      Optical coherence tomography based angle-resolved backscattering studies on bovine tendon and cartilage
      The difference in the genetic make up of the constituent molecules in collagen fibers in tendon and articular cartilage is what makes them mechanically and functionally different. A comparative study carried out on the differences in the angle-resolved back-scattering properties obtained from optical coherence tomography based studies on the two different types of scatterers: collagen I and collagen II fibers in bovine tendon and bovine articular cartilage sample, respectively, is ...
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    7. Evaluating the use of optical coherence tomography for the detection of epithelial cancers in vitro

      Evaluating the use of optical coherence tomography for the detection of epithelial cancers in vitro
      ...ad penetrated into the dermis. Louise E. Smith, Vanessa Hearnden, Zenghai Lu, Rod Smallwood, Keith D. Hunter, Stephen J. Matcher, Martin H. Thornhill, Craig Murdoch and Sheila MacNeil, "Evaluating the use of optical cohe...
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    8. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      ... have received about $1M in funding.  Ralph Tatam, Richard Hogg, Adrian Podoleanu, Ruikang Wang, Harry Coles, Steve Matcher, Rodney Smallwood, and Haida Liang are the top UK funding recipients and all received in excess ...
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    9. Feature Of The Week 7/3/11: Swept-Source Laser Based on a Quantum Dot Semiconductor Optical Amplifier

      Feature Of The Week 7/3/11: Swept-Source Laser Based on a Quantum Dot Semiconductor Optical Amplifier
      Researchers at the University of Sheffield have been very active in publishing novel results on high performance semiconductors for Optical Coherence Tomography. Recently in collaboration with Innolume they published on a swept-source laser based on a quantum-dot semiconductor optical amplifier. Below is a summary of that work.Swept source lasers (SSL) are a crucial component in Fourier domain optical coherence tomography (OCT) systems. Most SSLs use semiconductor optical amplifiers (SOA ...
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    10. 31-45 of 74 « 1 2 3 4 5 »
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  2. About Steven J. Matcher

    Steven J. Matcher

    Stephen Matcher graduated from Imperial College London with a BSc in Physics and subsequently a PhD in optical astronomy, where he used high-speed, low-light-level imaging to overcome atmospheric turbulence and achieve diffraction-limited ground-based imaging. He translated his expertise in low-light-level imaging into medicine at University College London, where he developed near-infrared spectroscopy techniques to study tissue oxygen delivery, especially in newborn infants at risk from birth asphyxia. He then joined the staff of the Physics department at the University of Exeter, where he established research programmes in visible light spectroscopy of skin and optical coherence tomography (OCT). In 2006 he joined the University of Sheffield where he is currently Reader in Biomedical Engineering. His chief research interest lies in the development and application of novel biophotonic imaging tools to aid the characterisation of native and engineered biological tissues. Primarily he works with OCT, including novel variants such as polarization-sensitive OCT for the non-invasive assessment of collagen organization and Doppler OCT for the measurement of fluid flow. He is currently collaborating with clinical colleagues to improve the detection of corneal stem cells post-implantation, to provide tools for the early detection and staging of epithelial cancer and to develop non-invasive tools to characterise skin barrier function. He also actively collaborates with the National Centre for III-V Technologies to develop improved light sources for biophotonic imaging.

  3. Quotes

    1. I am very pleased that the RAE is supporting my secondment to Michelson Diagnostics, a world leader in OCT imaging and I hope that my skills and expertise will be of practical benefit to the company
      In Dr Stephen Matcher Biomedical Imaging Expert Seconded to Michelson Diagnostics